2649 completed, 703 unknown, 469 recruiting, 289 terminated. 1665 Not applicable, 590 Phase 2, 519 Phase 4, 502 Phase 3, 360 Phase 1.
Follow Renal Insufficiency, Chronic: new trials by email Literature Review of Renal Insufficiency, Chronic trials Research Report on Renal Insufficiency, Chronic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MRI Technical Development and Applications in Kidney Disease Chronic Kidney Diseases, Kidney Transplantation | Not yet recruiting | University of Minnesota | 180 | 2028-06-30 | 2026-04-13 | |
| Veteran Centered Meal Intervention in Chronic Kidney Disease Medically tailored meals (MTMs) - Chronic Kidney Disease | Not applicable | Not yet recruiting | VA Office of Research and Development | 100 | 2027-10-01 | 2026-09-03 |
| Technology-enabled Social Network Intervention to Increase Live Donor Kidney Transplantation Digital education outreach intervention for kidney transplant access and human guide, Digital education outreach intervention for kidney transplant access only (unguided) - End-Stage Renal Disease, Chronic Kidney Diseases | Not applicable | Not yet recruiting | State University of New York at Buffalo | 550 | 2027-10-01 | 2026-10-20 |
| Anti-Interleukin-6 (IL6) in Calciphylaxis Tocilizumab - Calciphylaxis | Phase 1 | Not yet recruiting | Boston Medical Center | 10 | 2027-09-01 | 2026-07-16 |
| Kidney RISE: Randomized Integrated Supportive CarE Trial Kidney RISE - Chronic Kidney Disease (Stages 4 and 5) | Not applicable | Not yet recruiting | NYU Langone Health | 280 | 2027-05-01 | 2026-08-03 |
| Breakthrough - T1DM and Chronic Kidney Disease Tegoprubart, Islet Cell Transplant - Diabete Type 1, Chronic Kidney Disease | Phase 1 / Phase 2 | Recruiting | University of Chicago | 10 | 2027-04-29 | 2026-08-20 |
| PATH-03 Paraguay Feasibility Study ePATH System will be used to create an endoAVF - Kidney Disease, End-Stage | Not applicable | Not yet recruiting | Pathfinder Medical | 20 | 2027-03-01 | 2026-09-17 |
| Drone Transport of Deceased-Donor Kidney Grafts Between Two French Hospitals Before Transplantation: a Pilot Safety Study Kidney graft transport by autonomous unmanned aircraft (drone) between the procurement and transplantation centres - Kidney Failure, Chronic, Kidney Transplantation | Not applicable | Not yet recruiting | Nantes University Hospital | 5 | 2027-01-15 | 2026-10-01 |
| Potassium Containing Salt-Substitute in Hemodialysis-Dependent End Stage Kidney Disease Standard Table Salt, Salt Substitute - End Stage Kidney Disease | Not applicable | Not yet recruiting | NYU Langone Health | 20 | 2027-01-15 | 2026-03-12 |
| Patient-centred Intervention With Virtual Support for Obesity and Kidney Transplant Access Semaglutide, Virtual Weight Management Coaching - Obesity, Chronic Kidney Disease | Phase 4 | Not yet recruiting | Kristin Clemens | 880 | 2027-01-01 | 2026-10-05 |
| Finerenone for AKI: a Multicenter, Randomized, Placebo-Controlled Feasibility Pilot Trial Finerenone (BAY94-8862 ) 10 mg, Placebo - Acute Kidney Injury, Renal Insufficiency,Chronic | Not applicable | Not yet recruiting | Jean-Maxime Côté | 72 | 2027-01-01 | 2026-08-20 |
| Virtual Reality-Guided Imagery in Hemodialysis Patients ( VRGI-HD ) virtual reality-guided imagery (VRGI) - End-Stage Kidney Disease (ESKD) | Not applicable | Not yet recruiting | Islamic University of Najaf | 80 | 2027-01-01 | 2026-10-09 |
| Impact of Reducing the Dialysate Flow Rate in Chronic Hemodialysis on Dialysis Quality and Environmental Impact on Water Consumption Dialysate flow at 400mL/min, Dialysate flow at 500mL/min - Kidney Disease, Chronic | Not applicable | Not yet recruiting | Assistance Publique Hopitaux De Marseille | 250 | 2027-01-01 | 2026-07-22 |
| Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD) Endothelial cell collection - Obesity and Obesity-related Medical Conditions, Diabetes | Recruiting | Bettina Mittendorfer | 100 | 2027-01-01 | 2026-05-07 | |
| Left Atrial Appendage Occlusion in Dialysis Patients With Atrial Fibrillation: A Multicentre Pilot Study Dialysis, Chronic Kidney Disease (Stages 3b-5) | Not yet recruiting | Prince of Wales Hospital, Shatin, Hong Kong | 40 | 2026-12-05 | 2026-09-16 | |
| Study on Improving Blood Glucose Homeostasis With Dorzagliatin Tablets in the Treatment of Type 2 Diabetes Mellitus Patients With Moderate to Severe Chronic Renal Insufficiency Dorzagliatin, Linagliptin - Type 2 Diabetes Mellitus (T2DM), Chronic Renal Insufficiency | Not applicable | Withdrawn | Sun Yat-sen University | 2026-12-01 | 2026-10-16 | |
| Efficacy and Safety of Spironolactone in Pediatric Hemodialysis Patients With Anemia. Spironolactone (drug), Iron Supplement, Erythropoietin stimulating agent - Anemia | Phase 2 | Not yet recruiting | Ain Shams University | 40 | 2026-12-01 | 2026-07-20 |
| Clinical Performance of the Therapy Option FlexPoint of the PD Cycler Sleep•Safe Harmony PD cycler - Renal Failure, Chronic Kidney Disease | Not applicable | Not yet recruiting | Fresenius Medical Care Deutschland GmbH | 24 | 2026-12-01 | 2026-09-03 |
| Heart-Kidney-Diabetes Multidisciplinary Care MOdels for CardiovascuLar Health In Patients With Chronic Kidney DiSease and Diabetes: A PragmaTIC Cluster Randomized Controlled Trial (HOLISTIC) The intervention with the MCM is Kidney-Heart GDMT initiation and titration for dose optimization (as clinically tolerated), within 4 months of enrollment in the study. - Chronic Kidney Disease, Type II Diabetes | Phase 4 | Not yet recruiting | Baim Institute for Clinical Research | 570 | 2026-12-01 | 2026-09-10 |
| Unmasking Diabetes in Dialysis With Continuous Glucose Monitoring Continuous Glucose Monitoring (CGM) - End Stage Kidney Disease (ESKD), Hyperglycaemia | Not yet recruiting | Emory University | 180 | 2026-12-01 | 2026-10-19 |
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Kidney Failure, Chronic (1997) · Renal Insufficiency (282) · Kidney Diseases (262) · Hypertension (231) · Anemia (228) · Diabetes Mellitus (224) · Diabetes Mellitus, Type 2 (204) · Cardiovascular Diseases (180) · Heart Failure (131) · Acute Kidney Injury (124) · Inflammation (105) · Hyperparathyroidism, Secondary (95) · Motor Activity (94) · Diabetic Nephropathies (93)
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Exercise (67) · Darbepoetin alfa (54) · dapagliflozin (49) · paricalcitol (47) · Epoetin Alfa (46) · Sevelamer (46) · Blood Specimen Collection (45) · finerenone (39) · Tacrolimus (35) · Cholecalciferol (34) · Cinacalcet (34) · Mycophenolic Acid (33) · Standard of Care (32) · empagliflozin (32) · Spironolactone (29)
Amgen (68) · Bayer (54) · AstraZeneca (53) · Assiut University (45) · National Taiwan University Hospital (37) · Vantive Health LLC (34) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (33) · University of Pennsylvania (29) · VA Office of Research and Development (28) · Duke University (27) · University of Washington (27) · Novo Nordisk A/S (26) · Brigham and Women's Hospital (24) · Hospices Civils de Lyon (24) · Massachusetts General Hospital (24)
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Alp Ikizler, MD (17) · Jonathan Himmelfarb, MD (10)
PMID 36005278, PMID 40576086, PMID 35018639, PMID 36791280, PMID 35224730, PMID 37916745, PMID 33586138, PMID 37870148, PMID 32390133, PMID 38189593, PMID 33283264, PMID 34164803, PMID 36472416, PMID 37651553, PMID 32588430, PMID 33782940, PMID 38018702, PMID 38770818, PMID 33107592, PMID 39963952, PMID 23797006, PMID 41196655, PMID 19558344, PMID 23343061, PMID 23343062, PMID 32446407, PMID 32734207, PMID 36039153, PMID 38899545, PMID 39356039, PMID 39498822, PMID 40333016, PMID 40359056, PMID 41198855, PMID 41805697, PMID 18328118, PMID 20721651, PMID 23732715, PMID 27587605, PMID 28506446, PMID 28756065, PMID 28767349, PMID 30677788, PMID 31203241, PMID 33118160, PMID 34231877, PMID 36472884, PMID 36749544, PMID 37872654, PMID 37968132
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