46 completed, 16 unknown, 10 not yet recruiting, 4 recruiting. 19 Not applicable, 15 Phase 4, 12 Phase 2, 11 Phase 3, 3 Phase 1.
Follow Vascular Calcification: new trials by email Literature Review of Vascular Calcification trials Research Report on Vascular Calcification
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Analysis of the Influence of Dialysis Fluid Composition on Vascular Calcification in Patients With Chronic Kidney Disease Undergoing Hemodialysis Citrate dialysate with magensium supplementation, Acetate dialysate - Vascular Calcification, Hemodialysis | Not applicable | Not yet recruiting | Hospital Clinic of Barcelona | 80 | 2027-01-02 | 2026-09-16 |
| Relationship Between Insulin Dose and Complications in Type 1 Diabetes Routine/prescribed exogenous insulin dose - Diabetes Mellitus, Type 1 Diabetes, Cardiovascular Diseases (CVD) | Not yet recruiting | Rachel Miller | 80 | 2027-01-01 | 2026-11-02 | |
| Ramipril vs. Amlodipine in Pediatric Hemodialysis Patients Ramipril tablet, Amlodipine tablet - Endothelial Dysfunction, End-Stage Renal Disease | Phase 3 | Not yet recruiting | Ain Shams University | 50 | 2026-11-01 | 2026-10-21 |
| REducing Systemic Inflammation With LOw-dose Colchicine to ImproVE Cardiovascular Calcification in Chronic Kidney Disease: A Pilot Randomized Open-Label Trial Low-dose Colchicine at 0.5mg daily, Usual Care - Chronic Kidney Disease Mineral and Bone Disorder, Cognitive Function | Phase 2 | Not yet recruiting | University of Texas Southwestern Medical Center | 60 | 2026-10-30 | 2026-11-04 |
| Tissue Validation of Mammographic Breast Arterial Calcification in Mastectomy Specimens Breast Cancer, Vascular Calcification | Not yet recruiting | Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital | 100 | 2026-10-15 | 2026-10-15 | |
| an Observational Study Evaluting the Effectiveness and Safety of DKutting LL Noval Scoring Balloon Angioplasty for Vessel Preparation Facilitated by IVUS on the Lower Limb Ischemia Patients With Calcified Lesions DKutting LL scoring balloon angioplasty - Femoral Artery Stenosis, Angioplasty | Enrolling by invitation | The First Affiliated Hospital of Dalian Medical University | 58 | 2026-03-17 | 2026-04-03 | |
| Ultrasound Assessment of Arterial Medial Calcification in Endurance Athletes: A Prevalence Study Calcifications, Vascular | Not yet recruiting | University Hospital, Grenoble | 60 | 2026-02-01 | 2026-02-18 | |
| Comparison of RA-IVL and RA-SHP in Calcified Coronary Lesions Super High-Pressure Non-Compliant Balloon, Intravascular Lithotripsy System - Vascular Calcification | Not applicable | Not yet recruiting | Lin Zhao | 162 | 2026-01-01 | 2025-12-29 |
| A Study to Evaluate the Safety and Effectiveness of the FastWave Artero™ Peripheral Intravascular Lithotripsy (IVL) System in Adults With Peripheral Artery Disease (PAD) FastWave Artero™ Peripheral IVL System - Peripheral Artery Disease (PAD) | Not applicable | Not yet recruiting | FastWave Medical | 110 | 2025-12-01 | 2025-10-09 |
| GUIDE-CAC: Statin-Ezetimibe Without Aspirin vs. Statin Monotherapy With Aspirin in High Coronary Calcification Pitavastatin 4mg and ezetimibe 10mg, taken once daily, Pitavastatin 2 mg with aspirin 100 mg, taken once daily. - Primary Prevention, Vascular Calcification | Phase 4 | Recruiting | Asan Medical Center | 7435 | 2025-07-09 | 2025-08-07 |
| Pentoxifylline for Vascular Calcification in Kidney Disease Pentoxifylline 400 MG Oral Tablet, Conventional Medications for Chronic Kidney Disease - Chronic Kidney Disease, Vascular Calcification | Phase 1 / Phase 2 | Not yet recruiting | Mansoura University | 80 | 2025-04-15 | 2025-04-01 |
| Use of ETElcalcetidefor pReserving vitamiN K-dependent proteIn activiTY ITAlian Study Hemodialysis | Not yet recruiting | Istituto di Fisiologia Clinica CNR | 160 | 2024-05-01 | 2024-04-08 | |
| Immunomodulatory Effects of PCSK9 Inhibition 99mTc-tilmanocept SPECT/CT scanning - Atherosclerotic Cardiovascular Disease, Cardiovascular Diseases | Withdrawn | Massachusetts General Hospital | 2024-04-04 | 2025-09-26 | ||
| Calcium Reduction by Orbital Atherectomy in Western Europe Orbital Atherectomy - Vascular Calcification* / Diagnostic Imaging, Atherectomies, Coronary | Unknown | Erasmus Medical Center | 100 | 2024-03-15 | 2024-02-29 | |
| SEAPORT 1: Study of INZ-701 in Adults With Hemodialysis-Dependent End-Stage Kidney Disease INZ-701 - Calciphylaxis | Phase 1 | Completed | Inozyme Pharma | 11 | 2024-02-12 | 2026-08-24 |
| Potential Cross-Talk Between Arterial Calcifications Vascular Calcification, Atherosclerosis of Artery | Completed | Ankara Ataturk Sanatorium Training and Research Hospital | 921 | 2024-02-02 | 2025-03-26 | |
| Neutrophil Gelatinase-associated Lipocalin VS Vascular Calcification in Maintenance Hemodialysis Patients palicalcitol - Chronic Kidney Disease-Mineral and Bone Disorder | Phase 4 | Unknown | Xiaoyan Jia | 80 | 2023-04-01 | 2024-03-08 |
| SGLT2 Inhibitors in Non-Diabetic CKD: Effects on Vascular Calcification and Anemia Dapagliflozin (10Mg Tab) along with standard medical therapy, Placebo - Chronic Kidney Disease, Anemia | Phase 3 | Completed | Mansoura University | 100 | 2022-09-01 | 2026-01-15 |
| Shockwave IVL + DES Peripheral lithotripsy system (Shockwave Medical) - Peripheral Arterial Disease, Superficial Femoral Artery Stenosis | Completed | Marc Bosiers, MD | 50 | 2022-07-22 | 2026-04-27 | |
| Mammography and Breast Arterial Calcification: An Information-Sharing Trial BAC-Enhanced Letter, Waitlist Control - Mammography, Vascular Calcification | Not applicable | Active not recruiting | Icahn School of Medicine at Mount Sinai | 5492 | 2021-09-29 | 2026-04-16 |
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Renal Insufficiency, Chronic (18) · Kidney Failure, Chronic (12) · Cardiovascular Diseases (8) · Peripheral Arterial Disease (7) · Chronic Kidney Disease-Mineral and Bone Disorder (6) · Kidney Diseases (6) · Atherosclerosis (5) · Calcinosis (5) · Hyperparathyroidism, Secondary (5) · Inflammation (4) · Renal Insufficiency (4) · Vascular Diseases (4) · Coronary Artery Disease (3) · Hyperparathyroidism (3)
Metabolic Diseases (84) · Nutritional and Metabolic Diseases (84) · Calcium Metabolism Disorders (83) · Calcinosis (79) · Female Urogenital Diseases (37) · Female Urogenital Diseases and Pregnancy Complications (37) · Male Urogenital Diseases (37) · Urogenital Diseases (37) · Urologic Diseases (37) · Pathological Conditions, Signs and Symptoms (36) · Pathologic Processes (33) · Kidney Diseases (31) · Chronic Disease (29) · Disease Attributes (29) · Renal Insufficiency (25)
Calcitriol (3) · Cholecalciferol (3) · Cinacalcet (3) · Sevelamer (3) · Tablets (3) · Vitamin K 2 (3) · calcium acetate (3) · lanthanum carbonate (3) · Alendronate (2) · Calcium Carbonate (2) · Vitamin D (2) · Vitamin K 1 (2) · Amlodipine (1) · Aspirin (1) · Atorvastatin (1)
Assiut University (3) · Centre Hospitalier Universitaire, Amiens (3) · Ramathibodi Hospital (3) · Ain Shams University (2) · Genesis Medtech Corporation (2) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (2) · Mansoura University (2) · University Hospital, Montpellier (2) · University of California, San Francisco (2) · Abbott Medical Devices (1) · Ahmed Faisal Mohamed Mohamed Saleh (1) · Albany College of Pharmacy and Health Sciences (1) · Amgen (1) · Ankara Ataturk Sanatorium Training and Research Hospital (1) · Asan Medical Center (1)
United States (16) · China (7) · France (7) · Italy (5) · Egypt (4) · Germany (4) · Thailand (4) · Turkey (Türkiye) (3) · Belgium (2) · Canada (2) · Denmark (2) · Japan (2) · Spain (2) · Australia (1) · Austria (1)
Thomas Nickolas, MD, MS (2) · Abraham Rincon Bello, Dr. (1) · Alaattin Yildiz, MD (1) · Alessandra Brofferio, M.D. (1) · Alex Gold, MD (1) · Alex SR Souza, PhD (1) · Aluizio B Carvalho, PhD (1) · An Devriese, MD, PhD (1) · Ana Paula S Gueiros, MD (1) · Angela YM Wang, MD, PhD (1) · Antonia Perez Martin, MD (1)
PMID 34231877, PMID 40576086, PMID 22169620, PMID 38189593, PMID 10089993, PMID 10584989, PMID 10816185, PMID 11443763, PMID 12935835, PMID 12937218, PMID 14581387, PMID 14582032, PMID 15284307, PMID 15810001, PMID 16227647, PMID 16973975, PMID 17130273, PMID 17468488, PMID 18007136, PMID 18046319, PMID 18094365, PMID 18625626, PMID 18689371, PMID 18697901, PMID 18838561, PMID 19007931, PMID 19082528, PMID 19386744, PMID 19776145, PMID 20133489, PMID 20237066, PMID 20649879, PMID 20719580, PMID 21233416, PMID 21628633, PMID 21781006, PMID 22267443, PMID 22289649, PMID 22516722, PMID 22648294, PMID 22955514, PMID 23535831, PMID 23719555, PMID 24072176, PMID 24184249, PMID 24285428, PMID 24326161, PMID 24400802, PMID 24429407, PMID 24685669
R01AG019147 (1), R01CA251754 (1), R01HL069272 (1)