15 completed, 5 unknown, 4 active not recruiting, 3 recruiting. 8 Not applicable, 8 Phase 2, 6 Phase 3, 3 Phase 4, 1 Early Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Diagnostic Work-up of Nephrocalcinosis in Children Nephrocalcinosis | Not yet recruiting | Assiut University | 40 | 2026-10-20 | 2026-10-20 | |
| Treatment With Indapamide in Patients With Post-Surgical Hypoparathyroidism Indapamide 1.5 MG SR, Placebo - Hypoparathyroidism Post-surgical | Phase 4 | Recruiting | Lars Rejnmark | 24 | 2025-08-01 | 2025-08-11 |
| Prevelance of Hypercalciuria in Children With Steroid Dependent Nephrotic Syndrome Steroid-Dependent Nephrotic Syndrome; Hypercalciuria, Steroid Dependent Nephrotic Syndrome | Active not recruiting | Sohag University | 50 | 2024-01-01 | 2025-09-26 | |
| Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1 Encaleret, Standard of Care - Autosomal Dominant Hypocalcemia (ADH) | Phase 3 | Active not recruiting | Calcilytix Therapeutics, Inc., a BridgeBio company | 67 | 2023-01-06 | 2026-07-29 |
| ADH1 and ADH2 Disease Monitoring Study (DMS) Autosomal Dominant Hypocalcemia | Active not recruiting | Calcilytix Therapeutics, Inc., a BridgeBio company | 95 | 2022-01-20 | 2026-04-30 | |
| Multicenter, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Fluconazole in Hypercalcicuric Patients With Increased 1.25(OH) 2D Levels Fluconazole, Placebo - Nephrolithiasis, Nephrocalcinosis | Phase 2 | Completed | Hospices Civils de Lyon | 56 | 2021-01-13 | 2024-07-12 |
| Bone Mineral Density and Vascular Calcifications in the Population of Lithiasis Patients With Idiopathic Hypercalciuria Data extraction from medical files - Hypercalciuria; Idiopathic | Completed | Agnieszka Pozdzik | 22 | 2021-01-12 | 2023-02-09 | |
| Metabolic Workup in Patients Suffering From Kidney Stone Disease and Osteopenia CT scan, 24 hour urine collection - Urolithiasis, Renal Colic | Not applicable | Unknown | Ziv Hospital | 150 | 2019-10-01 | 2019-09-25 |
| Safety and Efficacy of Chlorthalidone in Type 1 Diabetes Chlorthalidone - Type 1 Diabetes Mellitus, Hypercalciuria | Phase 2 | Terminated | University of Rochester | 1 | 2019-06-28 | 2021-01-05 |
| The Impact of Phosphate Metabolism on Healthy Aging phosphate - Hypophosphatemia, Rickets | Early Phase 1 | Recruiting | Yale University | 30 | 2019-01-01 | 2026-05-27 |
| Vitamin D In the Prevention of Viral-induced Asthma in Preschoolers Vitamin D, Placebo - Asthma, Asthma Exacerbations | Phase 3 | Completed | Professor Francine Ducharme | 323 | 2018-10-01 | 2025-06-03 |
| Rifampin in CYP24A1-related Hypercalcemia and Hypercalciuria Rifampin - Idiopathic Infantile Hypercalcaemia - Severe Form, Genetic Disease | Phase 2 | Recruiting | Children's Hospital of Philadelphia | 60 | 2018-07-25 | 2026-10-13 |
| Comparison of the Impact of Diet vs Thiazide in BMD in Children With Idiopathic Hypercalciuria Diet for calciuria prevention, Hydrochlorothiazide - Hypercalciuria; Idiopathic, Nephrolithiasis | Not applicable | Unknown | Hospital Infantil de Mexico Federico Gomez | 90 | 2018-05-11 | 2019-05-15 |
| The Antibiotic Rifampin to Reduce High Levels of Blood and Urine Calcium in IIH Rifampin 150 mg, 300 mg capsules and 25 mg/mL oral suspension - Idiopathic Infantile Hypercalcemia - Mild Form | Phase 1 | Unknown | The Hospital for Sick Children | 5 | 2018-02-22 | 2021-08-31 |
| Recombinant Human rhPTH(1-34) VS Association Alfacalcidol/Hydrochlorothiazide in Severe Primary Hypoparathyroidism Teriparatide, Thiazide, Potassium sparing diuretic - Autosomal Dominant Hypocalcemia OR Primary Hypoparathyroidism Related to Other Cause But Complicated by Hypercalciuria Under Treatment | Phase 2 | Completed | Assistance Publique - Hôpitaux de Paris | 16 | 2017-06-06 | 2021-06-28 |
| Preterm Infants and Nephrocalcinosis Prematurity, Nephrocalcinosis | Completed | University of Utah | 56 | 2015-04-01 | 2017-03-13 | |
| ACTHAR GEL for Sarcoidosis-Associated Calcium Dysregulation: An Open-label Pilot Study ACTHAR Gel (adrenocorticotropic hormone) - Sarcoidosis, Hypercalcemia Due to Sarcoidosis | Phase 2 / Phase 3 | Unknown | Albany Medical College | 10 | 2015-02-01 | 2015-01-26 |
| Night Time Use of Thiazide Diuretics for Improved Reduction in Stone Risk in Stone Formers With Elevated Urine Calcium chlorthalidone, Hydrochlorothiazide - Kidney Stones | Not applicable | Completed | VA New York Harbor Healthcare System | 10 | 2014-02-01 | 2023-04-27 |
| The Effects of Estrogen Replacement Therapy in Postmenopausal Women With Hypercalciuria and Low Bone Mass Transdermal estradiol - Hypercalciuria, Hypercalciuria, Familial Idiopathic | Phase 2 | Terminated | University of Chicago | 1 | 2013-08-01 | 2018-12-10 |
| Treatment for Calcium Phosphate Kidney Stone Disease Placebo, Citric Acid, Potassium Citrate - Calcium Phosphate Kidney Stones | Phase 2 | Completed | University of Texas Southwestern Medical Center | 13 | 2012-07-01 | 2024-04-04 |
Showing 20 of 32. Sign in to see all of them.
Nephrolithiasis (10) · Nephrocalcinosis (9) · Hypercalcemia (7) · Hypoparathyroidism (6) · Kidney Calculi (6) · Bone Diseases, Metabolic (4) · Hypocalcemia (3) · Osteoporosis (3) · Urolithiasis (3) · Calcium Metabolism Disorders (2) · Hypercalciuric Hypocalcemia, Familial (2) · Metabolic Diseases (2) · Muscular Diseases (2) · Musculoskeletal Abnormalities (2)
Pathological Conditions, Signs and Symptoms (32) · Signs and Symptoms (32) · Urological Manifestations (32) · Female Urogenital Diseases and Pregnancy Complications (20) · Nutritional and Metabolic Diseases (20) · Female Urogenital Diseases (19) · Male Urogenital Diseases (19) · Urogenital Diseases (19) · Urologic Diseases (19) · Metabolic Diseases (18) · Kidney Diseases (17) · Calcium Metabolism Disorders (13) · Urolithiasis (11) · Water-Electrolyte Imbalance (11) · Calcinosis (9)
Cholecalciferol (3) · Hydrochlorothiazide (3) · Potassium Citrate (3) · Chlorthalidone (2) · Rifampin (2) · Vitamin D (2) · Acetazolamide (1) · Adrenocorticotropic Hormone (1) · Amiloride (1) · Calcium Citrate (1) · Citric Acid (1) · Diet (1) · Diet, Sodium-Restricted (1) · Ergocalciferols (1) · Estradiol (1)
Calcilytix Therapeutics, Inc., a BridgeBio company (2) · University of Texas Southwestern Medical Center (2) · VA New York Harbor Healthcare System (2) · Agnieszka Pozdzik (1) · Albany Medical College (1) · Assistance Publique - Hôpitaux de Paris (1) · Assiut University (1) · Children's Hospital of Philadelphia (1) · Children's Mercy Hospital Kansas City (1) · Columbia University (1) · Creighton University (1) · Hospices Civils de Lyon (1) · Hospital Infantil de Mexico Federico Gomez (1) · Indiana Kidney Stone Institute (1) · Indiana University (1)
United States (19) · Canada (4) · France (4) · Denmark (3) · Italy (3) · Australia (2) · Belgium (2) · Japan (2) · Netherlands (2) · United Kingdom (2) · Czechia (1) · Egypt (1) · Finland (1) · Germany (1) · Israel (1)
Agnes Linglart, MD, PhD (1) · Ahlam B Ali, prof (1) · Anne Blanchard, MD, PhD (1) · Ari Auron, MD (1) · Charles Y. C. Pak (1) · Clemens Bergwitz, MD (1) · David Goldfarb, MD (1) · David S Goldfarb, MD (1) · Elena Ortiz, Master (1) · Etienne Sochett, MD (1) · Francine M Ducharme, MD (1) · J C Gallagher, MD (1) · James Lingeman, MD (1)
PMID 20042524, PMID 22431675, PMID 23386641, PMID 24166866, PMID 24937025, PMID 30137647, PMID 31215092, PMID 35710560, PMID 36018496, PMID 40194294, PMID 41966354, PMID 42871976
1UL1TR001863-01 (1), 2016 (1), K23DK114477 (1), R01AG028168 (1), R01DK112955 (1), R21DK097476 (1)