25 unknown. 25 Phase 2, 5 Phase 3, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 25 | Unknown 25 |
| Phase 3 | 5 | Unknown 5 |
| Phase 1 | 3 | Unknown 3 |
Follow Brain Damage, Chronic: new trials by email Literature Review of Brain Damage, Chronic trials Research Report on Brain Damage, Chronic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lateral Cord Magnetic Stimulation For Refractory Spastic Cerebral Palsy Magnetic Spinal Stimulation - Spastic Cerebral Palsy, Dysarthria | Phase 2 / Phase 3 | Unknown | Sociedad Argenttina de Neuromodulación | 20 | 2024-11-18 | 2023-11-21 |
| Upper Limb Somatosensory Discrimination Therapy and Dose-matched Motor Therapy in Children and Adolescents With Unilateral Cerebral Palsy Upper limb somatosensory discrimination therapy, Upper limb motor therapy - Cerebral Palsy, Spastic, Hemiplegic Cerebral Palsy | Phase 2 | Unknown | Hilde Feys | 50 | 2023-12-09 | 2024-02-07 |
| Spinal Cord Innovation in Pediatrics (SCiP) to Treat SensoriMotor Function in Children Cerebral Palsy: Protocol for a Randomized Controlled Trial SCiP - Cerebral Palsy | Phase 2 | Unknown | SpineX Inc. | 60 | 2023-09-01 | 2023-02-09 |
| Magnesium Sulphate Neuroprotective Strategies for Preterm Deliveries Magnesium sulfate loading with maintenance dose, Magnesium sulfate loading dose only - Premature Birth, NEUROPROTECTION | Phase 2 / Phase 3 | Unknown | Zagazig University | 336 | 2023-01-20 | 2023-07-14 |
| INcobotulinumtoxina in ChIldren Upper and Lower Limb sPasticITy (INCIPIT) IncobotulinumtoxinA 100 UNT [Xeomin] - Spastic Cerebral Palsy | Phase 2 | Unknown | Universita di Verona | 30 | 2022-06-01 | 2022-04-22 |
| Treatment of Children With Cerebral Palsy With Autologous Umbilical Cord Blood, a Pilot Study Autologous umbilical cord blood transfusion, placebo - Cerebral Palsy | Phase 2 | Unknown | Sheba Medical Center | 72 | 2020-07-08 | 2021-01-20 |
| Estimation of the Safety and Efficiency Transfusion of HLA Matched CBU in Patients With CP Low HLA group CBU infusion, High HLA group CBU infusion, Standard therapy - Cerebral Palsy | Phase 2 | Unknown | State-Financed Health Facility "Samara Regional Medical Center Dinasty" | 150 | 2019-09-01 | 2023-01-18 |
| Outcomes Mandate National Integration With Cannabis as Medicine Cannabis, Medical, RYAH-Medtech Inhaler - Chronic Pain, Chronic Pain Syndrome | Phase 2 | Unknown | OMNI Medical Services, LLC | 200000 | 2018-12-01 | 2022-06-02 |
| Treating Severe Brain-injured Patients With Apomorphine Apomorphine Hydrochloride 50Mg/10mL Prefilled Syringe - Disorder of Consciousness | Phase 2 | Unknown | University of Liege | 8 | 2018-10-03 | 2022-02-09 |
| Allogenic Cord Blood Transfusion in Patients With Cerebral Palsy CP CB-MNC injection, Standard therapy - Cerebral Palsy | Phase 2 | Unknown | State-Financed Health Facility "Samara Regional Medical Center Dinasty" | 40 | 2018-01-12 | 2023-01-18 |
| Efficacy of Allogeneic Umbilical Cord Derived Hematopoietic and Mesenchymal Stem Cells in Cerebral Palsy MNC, MSC, Control - Cerebral Palsy, Spastic | Phase 2 | Unknown | Tehran University of Medical Sciences | 108 | 2017-07-23 | 2019-01-08 |
| A Trial Evaluating Effects of COMT Inhibition in Patients With Acquired Brain Injury Tolcapone 200 MG, Placebo - Brain Injuries, Brain Injuries, Traumatic | Phase 2 | Unknown | Sheppard Pratt Health System | 16 | 2017-07-20 | 2017-09-06 |
| Bone Marrow-Derived Stem Cell Transplantation for the Treatment of Cerebral Palsy Stem Cell Therapy - Cerebral Palsy | Phase 1 / Phase 2 | Unknown | Stem Cells Arabia | 50 | 2016-09-01 | 2020-03-17 |
| G-CSF and Autologous Cord Blood Infusion in Cerebral Palsy G-CSF (Leucostim), CB (autologous cord blood), Placebo (Normal saline) - Cerebral Palsy | Phase 2 | Unknown | Hanyang University Seoul Hospital | 88 | 2016-07-01 | 2016-08-15 |
| A Study of IBRF Disorders of Consciousness Advanced Care/MultiModal Care Protocol in Severe Disorders of Consciousness Polypharmacy using FDA-approved products, Median Nerve Stimulation (MNS), Nutraceutical Supplementation - Brain Injury | Phase 1 / Phase 2 | Unknown | International Brain Research Foundation | 30 | 2016-03-01 | 2016-09-02 |
| The Effects of Cannabis on Dystonia and Spasticity on Pediatric Patients Avidekel oil, Enriched Avidekel oil - Spasticity, Dystonia | Phase 2 | Unknown | Wolfson Medical Center | 40 | 2015-07-01 | 2015-08-18 |
| Intrathecal Stem Cells for Cerebral Palsy Phase II Autologous Stem Cell Transplantation - Cerebral Palsy | Phase 2 | Unknown | Hospital Universitario Dr. Jose E. Gonzalez | 60 | 2013-09-01 | 2014-09-04 |
| Application of Botulinum Toxin Type A in Salivary Glands in the Treatment of Drooling in Patients With Cerebral Palsy BOTULINUM NEUROTOXIN TYPE-A - Sialorrhea, Cerebral Palsy | Phase 2 / Phase 3 | Unknown | Hospital Vall d'Hebron | 60 | 2011-11-01 | 2012-10-30 |
| Establishment of Clinical Basis for Hematopoietic Growth Factors Therapy in Brain Injury Combination injection of EPO and G-CSF, Injection of normal saline - Neurological Diseases, Ischemic Stroke | Phase 1 / Phase 2 | Unknown | Yonsei University | 60 | 2011-07-05 | 2020-12-28 |
| Safety and Efficacy of Bone Marrow MNC for the Treatment of Cerebral Palsy in Subjects Below 15 Years Intra thecal inj of autologous MNC - Cerebral Palsy | Phase 2 / Phase 3 | Unknown | Chaitanya Hospital, Pune | 100 | 2011-03-01 | 2014-09-17 |
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Cerebral Palsy (20) · Muscle Spasticity (4) · Persistent Vegetative State (3) · Brain Injuries (2) · Brain Injuries, Traumatic (2) · Consciousness Disorders (2) · Ischemic Stroke (2) · Neurologic Manifestations (2) · Acquired Immunodeficiency Syndrome (1) · Amyotrophic Lateral Sclerosis (1) · Anemia, Sickle Cell (1) · Anxiety Disorders (1) · Autistic Disorder (1) · Bipolar Disorder (1) · Brain Injury, Chronic (1)
Brain Diseases (25) · Central Nervous System Diseases (25) · Nervous System Diseases (25) · Pathological Conditions, Signs and Symptoms (13) · Signs and Symptoms (11) · Neurologic Manifestations (9) · Muscular Diseases (5) · Musculoskeletal Diseases (5) · Muscle Hypertonia (4) · Neurobehavioral Manifestations (4) · Neuromuscular Manifestations (4) · Pathologic Processes (4) · Craniocerebral Trauma (3) · Disease Attributes (3)
Standard of Care (3) · Granulocyte Colony-Stimulating Factor (2) · Apomorphine (1) · Botulinum Toxins, Type A (1) · Constraint Induced Movement Therapy (1) · Control Groups (1) · Exercise Test (1) · Flumazenil (1) · Lacteol (1) · Lamotrigine (1) · Medical Marijuana (1) · Minocycline (1) · Physical Therapy Modalities (1) · Saline Solution (1) · Sensation (1)
State-Financed Health Facility "Samara Regional Medical Center Dinasty" (2) · Assaf-Harofeh Medical Center (1) · Chaitanya Hospital, Pune (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Fondazione IRCCS Policlinico San Matteo di Pavia (1) · Hanyang University Seoul Hospital (1) · Hilde Feys (1) · Hospital Universitario Dr. Jose E. Gonzalez (1) · Hospital Vall d'Hebron (1) · International Brain Research Foundation (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1) · OMNI Medical Services, LLC (1) · Sheba Medical Center (1) · Sheppard Pratt Health System (1) · Sociedad Argenttina de Neuromodulación (1)
United States (4) · Israel (3) · Belgium (2) · Russia (2) · South Korea (2) · Argentina (1) · Canada (1) · Egypt (1) · India (1) · Iran (1) · Italy (1) · Mexico (1) · Spain (1)
Adam Kirton, MD MSc FRCPC (1) · Ali Reza Moaeidi, MD (1) · Amirali Hamidieh, MD (1) · Amro Alnemr, M.D. (1) · Anahita Majma, MD (1) · Anant E Bagul, M.S. (1) · Consuelo Mancias-Guerra, MD (1) · Dr. Ryan O Lakin, MD JD (1) · Edward Taub, PhD (1) · Eli Lahat, MD Proffesor (1) · Hadi Montazerlotfelahi, MD (1) · Hilde Feys, MSc, PhD (1) · Hytham Atia, M.D. (1) · John F. McLaughlin (1)
PMID 12529557, PMID 15037681, PMID 16108461, PMID 19416339, PMID 24100132, PMID 24909743, PMID 25113573, PMID 25593079, PMID 26745476, PMID 27029628, PMID 30941094, PMID 34362453, PMID 35351020, PMID 37564370, PMID 38409060, PMID 39624459, PMID 42156830