14 completed. 14 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 14 | Completed 14 |
Follow Bradycardia: new trials by email Literature Review of Bradycardia trials Research Report on Bradycardia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hyoscine Butylbromide for Prevention of Bradycardia During Cesarean Section Hyoscine Butylbromide 20 Mg/mL Solution for Injection Ampoule, Normal saline - Bradycardia, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use | Phase 4 | Completed | Assiut University | 173 | 2019-10-10 | 2020-03-03 |
| Atropine or Ephedrine Pretreatment for Preventing Bradycardia in Elderly Patients normal saline, atropine 0.5mg, ephedrine 8mg - Anesthesia, Spinal, Dexmedetomidine | Phase 4 | Completed | Ajou University School of Medicine | 102 | 2019-06-25 | 2021-02-04 |
| Cardiac Rehabilitation After Pacemaker Implantation cardiac rehabilitation - Bradycardia, Pacemaker | Phase 4 | Completed | Pusan National University Hospital | 27 | 2018-04-10 | 2021-08-20 |
| Safety of Sugammadex for the Reversal of Neuromuscular Blockade in American Society of Anesthesiologists (ASA) Class 3 or 4 Participants (MK-8616-145) Sugammadex 2 mg/kg, Sugammadex 4 mg/kg, Sugammadex 16 mg/kg - Reversal of Neuromuscular Blockade | Phase 4 | Completed | Merck Sharp & Dohme LLC | 344 | 2017-12-20 | 2020-10-08 |
| Anticholinergic Premedication for Sedation With Dexmedetomidine During Spinal Anesthesia Atropine, Dexmedetomidine, Ephedrine - Bradycardia | Phase 4 | Completed | Sira Bang | 120 | 2015-08-01 | 2016-01-18 |
| Heart Rate Response to Atropine Doses Less Than 0.1mg IV to Anesthetized Infants Atropine - Bradycardia, Arrhythmias | Phase 4 | Completed | State University of New York at Buffalo | 60 | 2013-02-01 | 2023-04-06 |
| 0.6 vs. 1.2 mg Atropine Together With Neostigmine 2.5 mg on Heart Rate in Patient Receiving Muscle Relaxant Atropine 0.6 mg, Atropine 1.2 mg - Bradycardia, Neostigmine Adverse Reaction | Phase 4 | Completed | Mahidol University | 40 | 2012-03-01 | 2014-07-10 |
| Falls and Cardiovascular Events in Pacemaker Patients Fill out Questionnaire - Bradycardia | Phase 4 | Completed | Medtronic Cardiac Rhythm and Heart Failure | 87 | 2009-08-01 | 2025-07-03 |
| Avoid FFS - Use of the Atrial Pacemaker Lead 1699 With Very Short Tip Ring Spacing to Avoid Far Field Sensing pacemaker implantation - Atrial Fibrillation, Bradycardia | Phase 4 | Completed | Abbott Medical Devices | 204 | 2006-12-01 | 2019-02-04 |
| Effectiveness of Pacemaker With Closed Loop Stimulation Compared to Pacemakers With and Without Standard Rate Response Closed Loop Stimulation (CLS), Standard Rate Adaptive (R) Technology, Non-rate adaptive (DDD) pacing - Bradycardia | Phase 4 | Completed | Biotronik, Inc. | 1491 | 2006-05-01 | 2012-12-20 |
| ULTRA Study for Pacemaker Patients Pacemaker with Automatic Capture - Bradycardia | Phase 4 | Completed | Boston Scientific Corporation | 950 | 2005-07-01 | 2007-07-10 |
| Atropine for Prevention of Dysrhythmias Caused by Percutaneous Ethanol Instillation for Hepatoma Therapy Atropine, Placebo - Arrhythmia, Respiratory Arrest | Phase 4 | Completed | Medical University of Vienna | 31 | 2003-10-01 | 2008-01-25 |
| Austria Study - Analysis of Difference Between Active and Passive Fixation Leads Flextend II, Fineline 2, Fineline Atrial J, Selute Picotip - Bradycardia, Heart Block | Phase 4 | Completed | Guidant Corporation | 120 | 2003-09-01 | 2015-03-17 |
| LIFE Study - Limiting Chronotropic Incompetence for Pacemaker Recipients sensor programming - Bradycardia | Phase 4 | Completed | Boston Scientific Corporation | 1500 | 2003-07-01 | 2017-05-18 |
Arrhythmias, Cardiac (3) · Sick Sinus Syndrome (2) · Tachycardia (2) · Apnea (1) · Atrial Fibrillation (1) · Carcinoma, Hepatocellular (1) · Fractures, Bone (1) · Heart Block (1)
Cardiovascular Diseases (14) · Heart Diseases (14) · Pathologic Processes (14) · Pathological Conditions, Signs and Symptoms (14) · Arrhythmias, Cardiac (11) · Cardiac Conduction System Disease (4) · Arrhythmia, Sinus (2) · Adenocarcinoma (1) · Carcinoma (1) · Digestive System Diseases (1) · Digestive System Neoplasms (1) · Heart Block (1) · Liver Diseases (1) · Liver Neoplasms (1) · Neoplasms (1)
Atropine (5) · Ephedrine (2) · Saline Solution (2) · Butylscopolammonium Bromide (1) · Cardiac Rehabilitation (1) · Dexmedetomidine (1) · Glycopyrrolate (1) · Neostigmine (1) · Rocuronium (1) · Solutions (1) · Sugammadex (1) · Vecuronium Bromide (1)
Boston Scientific Corporation (2) · Abbott Medical Devices (1) · Ajou University School of Medicine (1) · Assiut University (1) · Biotronik, Inc. (1) · Guidant Corporation (1) · Mahidol University (1) · Medical University of Vienna (1) · Medtronic Cardiac Rhythm and Heart Failure (1) · Merck Sharp & Dohme LLC (1) · Pusan National University Hospital (1) · Sira Bang (1) · State University of New York at Buffalo (1)
United States (4) · Austria (3) · South Korea (3) · Germany (2) · Denmark (1) · Egypt (1) · Switzerland (1)
Arnulf Ferlitsch, MD (1) · Bruce Koplan, MD (1) · C Nimeth, MD (1) · Christof Kolb, MD (1) · Freddy Abi-Samra, MD (1) · James Coman, MD (1) · Jerrold Lerman, MD FRCPC (1) · Michael Kuehne, Dr. med. (1) · Ray Moser, PhD (1) · Sira Bang, MD PhD (1) · Sirilak Suksompong, MD (1)
PMID 19018977, PMID 22745661, PMID 22858177, PMID 23419655, PMID 25762533, PMID 29908371, PMID 34711192, PMID 35448942
2017 (1)