35 completed, 7 unknown, 3 recruiting, 1 not yet recruiting. 14 Not applicable, 12 Phase 4, 8 Phase 3, 7 Phase 1, 5 Phase 2.
Follow Butylscopolammonium Bromide: new trials by email Literature Review of Butylscopolammonium Bromide trials Research Report on Butylscopolammonium Bromide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Imaging of Endometriosis With Total-body PET-CT (PET-Endo) PET/CT, PET/MRI, Buscopan 20 MG/ML Injectable Solution - Endometriosis | Recruiting | University of Edinburgh | 30 | 2026-04-08 | 2026-05-27 | |
| A Clinical Study to Evaluate the Efficacy and Safety of Hyoscine Butylbromide Capsules for Preoperative Preparation in Painless Gastrointestinal Endoscopy Procedures Hyoscine Butylbromide - Painless Gastrointestinal Endoscopy | Not applicable | Not yet recruiting | Shanghai Jiao Tong University School of Medicine | 74 | 2026-02-01 | 2026-01-20 |
| Hyoscine Butylbromide During Transcystic Papillary Balloon Dilation for Choledocholithiasis Hyoscine Butylbromide - Choledocholithiasis, Common Bile Duct Stones | Not applicable | Recruiting | Riga East Clinical University Hospital | 50 | 2026-01-04 | 2026-09-11 |
| Oral Hyoscine vs Lidocaine-Prilocaine Spray vs Placebo for HSG Pain Relief Oral Hyoscine butylbromide and Placebo Spray, Topical lidocaine-prilocaine spray and placebo oral tablet, Double Placebo - Hysterosalpingography | Not applicable | Completed | Cairo University | 102 | 2025-10-03 | 2026-06-11 |
| Effect of Hyoscine- Bromide on Duration of the First Stage of Labor hyoscine butylbromide, normal saline - Labor | Not applicable | Unknown | Ain Shams University | 60 | 2023-09-27 | 2023-10-06 |
| Valethamate Bromide Versus Hyoscine Butyl Bromide in Reducing Labour Duration Among Primigravida Valethamate Bromide, Hyoscine butylbromide, Sterile water - Labour Duration, Primigravida | Not applicable | Completed | Federal Teaching Hospital Abakaliki | 165 | 2023-09-01 | 2026-03-16 |
| How to Reduce Pain in Patients Undergoing Office Hysteroscopy. Celecoxib 200 mg, Hyoscine-N-butyl bromide (HBB), placebo tablet - Pain | Not applicable | Unknown | Cairo University | 180 | 2023-06-13 | 2023-06-20 |
| SAINT: Safe Induction of Labor Trial Buscopan 20 MG/ML Injectable Solution, Sodium bicarbonate, Placebo - Labor Complication, Induced; Birth | Phase 3 | Recruiting | Oslo University Hospital | 3000 | 2023-01-03 | 2024-04-04 |
| Hyoscine Butyl-bromide Versus Ondansetron for Nausea and Vomiting During Cesarean Section Under Spinal Anesthesia Hyoscine N Butylbromide, Ondansetron, Saline - Vomiting | Phase 4 | Completed | Assiut University | 165 | 2021-10-01 | 2023-03-16 |
| Management of Abdominal Pain in Acute Gastroenteritis Patients With Hyoscine Butylbromide Hyoscine N Butylbromide, Placebo - Acute Gastroenteritis, Abdominal Pain | Phase 4 | Completed | Ankara City Hospital Bilkent | 50 | 2021-09-08 | 2022-01-04 |
| The Effect of Hyoscine-n-butylbromide on Nausea and Pain in Laparoscopic Cholecystectomy hyoscine-n-butylbromide, ondansetron, • hyoscine-n-butylbromide • ondansetron - Cholecystitis, Pain | Phase 4 | Completed | Saglik Bilimleri Universitesi | 134 | 2020-11-15 | 2025-04-17 |
| The Effect of Hyoscine-N-butylbromide (HBB, Buscopan) in Augmented Labour Among Primigravidae Hyoscine Butylbromide, Placebo - Labor Long | Phase 4 | Completed | National University of Malaysia | 110 | 2019-12-01 | 2022-04-06 |
| Hyoscine Butylbromide for Prevention of Bradycardia During Cesarean Section Hyoscine Butylbromide 20 Mg/mL Solution for Injection Ampoule, Normal saline - Bradycardia, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use | Phase 4 | Completed | Assiut University | 173 | 2019-10-10 | 2020-03-03 |
| Hyoscine Butylbromide Effect on Duration of Labor Hyoscine Butylbromide 20Mg/1mL Injection, Saline Solution - Labor | Not applicable | Completed | Saint Thomas Hospital, Panama | 218 | 2019-07-12 | 2019-12-06 |
| A Novel Usage of Transdermal Scopolamine in Reducing Narcotic Usage in Outpatient Hand Surgery Scopolamine Patch (Transderm V) - Post Operative Pain Management | Completed | Alexander M Spiess, MD | 74 | 2019-06-25 | 2022-09-08 | |
| BUSCLAB - Buscopan to Prevent Slow Progress in Labor Butylscopolamine Bromide 20 MG/ML, Sodium Chloride 9mg/mL - Labor (Obstetrics)--Complications, Labor; Prolonged, First Stage | Phase 3 | Completed | Oslo University Hospital | 250 | 2019-05-25 | 2022-12-20 |
| 4FMFES-PET Imaging of Endometrial and Ovarian Cancers Loperamide Pill, hyoscine-n-butylbromide - Endometrial Cancer, Ovarian Cancer | Phase 1 / Phase 2 | Completed | Centre de recherche du Centre hospitalier universitaire de Sherbrooke | 53 | 2018-09-01 | 2024-05-13 |
| A Trial for Peroperative Procedure and Postoperative Pain After Rectal Misoprostol or Rectal Hyoscine Administration Misoprostol, Hyoscine butyl bromide - Hysteroscopic Surgery, Pain, Postoperative | Not applicable | Completed | Bezmialem Vakif University | 120 | 2018-06-11 | 2018-12-27 |
| Efficacy of Hyoscine-n-butylbromide in Catheter-related Bladder Discomfort After Elective Cesarean Section. hyoscine-n-butylbromide, control group - Catheter Related Bladder Discomfort | Not applicable | Completed | Cairo University | 92 | 2018-05-30 | 2022-01-13 |
| Effect Of Intravenous Hyoscine -N-Butyl Bromide In Management Of Prolonged Labor In Nulliparous Hyoscine N Butylbromide, Normal Saline 0.9% - Prolonged Labor | Not applicable | Completed | Cairo University | 100 | 2018-03-02 | 2021-10-07 |
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Pain (5) · Abdominal Pain (2) · Colic (2) · Nausea (2) · Ovarian Neoplasms (2) · Vomiting (2) · Abdomen, Acute (1) · Acute Pain (1) · Alzheimer Disease (1) · Bile Duct Diseases (1) · Bradycardia (1) · Cholecystitis (1) · Choledocholithiasis (1) · Dysmenorrhea (1) · Dyspepsia (1)
Boehringer Ingelheim (8) · Assiut University (5) · Cairo University (5) · Ain Shams University (2) · Oslo University Hospital (2) · Ahmed M Maged, MD (1) · Alexander M Spiess, MD (1) · Ankara City Hospital Bilkent (1) · AstraZeneca (1) · Bezmialem Vakif University (1) · Centre de recherche du Centre hospitalier universitaire de Sherbrooke (1) · Changhai Hospital (1) · Chulalongkorn University (1) · Federal Teaching Hospital Abakaliki (1) · Kocaeli University (1)
Egypt (10) · Turkey (Türkiye) (4) · United Kingdom (4) · Canada (3) · China (3) · Norway (2) · Thailand (2) · United States (2) · Belgium (1) · Germany (1) · Latvia (1) · Malaysia (1) · Nigeria (1) · Panama (1) · Peru (1)
Ahmed Maged (2) · Ahmed Maged, MD (1) · Aida Hani Mohd Kalok (1) · Alexander Spiess, MD (1) · Assumpta N Nweke (1) · Dmitrijs Aleksandrovs, Dr. (1) · Eman A Hussein, MD (1) · Igors Ivanovs, Asoc.Prof. (1) · Inti Qurashi, MBChB (1) · Kaichun Wu, M.D., Prof. (1)
PMID 22463973, PMID 27871302, PMID 31236286, PMID 33257343, PMID 33983512, PMID 34002866, PMID 34413142, PMID 35448942, PMID 38547322, PMID 39438126, PMID 40032397