8 completed, 6 unknown, 2 recruiting, 2 terminated. 6 Not applicable, 3 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 3, Terminated 2, Recruiting 1 |
| Phase 3 | 3 | Completed 1, Recruiting 1, Withdrawn 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow Fever of Unknown Origin: new trials by email Literature Review of Fever of Unknown Origin trials Research Report on Fever of Unknown Origin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of FDG-PET/CT and CECT-CAP as Upfront Imaging Modality for the Diagnosis of Pyrexia of Unknown Origin FDG-PET, CECT, Standard care of therapy - Pyrexia | Not applicable | Recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 132 | 2026-04-09 | 2026-10-05 |
| The Investigators Will Evaluate the Diagnostic Performance of [18F]-AlF-FAPI-74 PET/CT in Inflammatory Disorders and Compare it With the Current Gold Standard for Inflammation, FDG PET/CT, in Three Patient Cohort: Patients Presenting With Fever of Unknown Origin, IgG4-RD and AxSpA. [18F]AlF-FAPI-74 PET/CT - Fever of Unknown Origin, IgG4 Related Disease | Phase 2 / Phase 3 | Recruiting | Universitaire Ziekenhuizen KU Leuven | 140 | 2025-09-17 | 2026-04-17 |
| Primary Care-Hospital Embedding: a Prospective, Multicentric, Observational Study Outpatient visit - Heart Failure, Chronic Obstructive Pulmonary Disease | Active not recruiting | Rovere Querini Patrizia | 246 | 2023-02-13 | 2025-06-22 | |
| Utility of 18F-FDG PET/CT for Suspected Infection in the Inpatient Setting: a Single Centre Retrospective Cohort Study 18F-FDG PET/CT - Fever of Unknown Origin, Inflammation of Unknown Origin | Completed | University of Adelaide | 266 | 2022-01-04 | 2026-02-24 | |
| Fever of Unknown Origin (FUO) in Elderly Patients observational study - Fever of Unknown Origin | Withdrawn | Universitair Ziekenhuis Brussel | 2021-10-01 | 2026-05-04 | ||
| PLACE OF THE 18F-FDG-PET/CT IN THE DIAGNOSTIC WORKUP IN PATIENTS WITH CLASSICAL FEVER OF UNKNOWN ORIGIN (FUO) Fever of Unknown Origin | Completed | University Hospital, Montpellier | 44 | 2020-12-08 | 2021-04-20 | |
| PEMF Therapy to Treat Lingering Symptoms of Lyme Disease After Treatment With Antibiotics Scientific Consciousness Interface Operations (SCIO) Class II FDA approved medical device - Lyme Disease, Lyme Neuroborreliosis | Not applicable | Terminated | Kasey Phifer | 20 | 2020-10-07 | 2022-04-13 |
| Causes of FUO in Infants and Children tuberculin test - Fever of Unknown Origin | Unknown | Assiut University | 50 | 2019-10-01 | 2019-08-29 | |
| Fever of Unknown Orgin Registry in Internal Medicine Unit and Infectious Disease Units not aplicable since it is a Registry - Fever of Unknown Origin | Unknown | Fadoi Foundation, Italy | 100 | 2019-09-19 | 2022-02-24 | |
| 68Ga Citrate PET/MRI for Evaluation of Fever of Unknown Origin (FUO) 68Ga-Citrate PET/MRI, 67Ga-Citrate SPECT, Positron Emission Tomography - Fever of Unknown Origin | Phase 3 | Withdrawn | Carina Mari Aparici | 2019-01-15 | 2022-08-22 | |
| Influence of Compound Qingre Granule on the Inflammatory Markers in Patient of FUO With Excess-heat Syndrome Compound Qingre Granule - Fever of Unknown Origin | Unknown | Beijing Friendship Hospital | 80 | 2016-01-01 | 2016-03-01 | |
| Evaluation of Diagnosis of Fever and Biologic Inflammatory Syndrome of Unknown Origin Fever of Unknown Origin | Completed | University Hospital, Grenoble | 39 | 2015-12-01 | 2018-10-10 | |
| Clinical Research for the Diagnosis of Tick-borne Diseases in Patients With Unexplained Acute Fever diagnostic methods - Fever of Unknown Origin, Tick-borne Diseases | Unknown | Beijing Friendship Hospital | 200 | 2015-03-01 | 2016-07-26 | |
| Rapid Viral Diagnostics in Adults to Reduce Antimicrobial Consumption and Duration of Hospitalization Rapid diagnostics using Anyplex TMII RV16 Detection, Delayed diagnostics Anyplex TMII RV16 Detection - Respiratory Virus Infection, Fever of Unknown Origin | Not applicable | Completed | University of Oulu | 900 | 2014-09-01 | 2016-01-11 |
| PET CT in Suspected CIED Infection, a Pilot Study - PET Guidance I PET CT - Complications, Infective Endocarditis | Unknown | National Institute of Cardiology, Warsaw, Poland | 40 | 2014-03-01 | 2015-05-28 | |
| A Two-step Method Apparently Improved the Physicians' Level of Diagnosis Decision-making for Adult Patients With FUO Two-step diagnostic strategy - Fever of Unknown Origin | Unknown | Tongji Hospital | 600 | 2014-01-01 | 2018-05-07 | |
| PET-MRI in Diagnosing Patients With Cancer, Cardiac Diseases, or Neurologic Diseases positron emission tomography, computed tomography, magnetic resonance imaging - Cardiac Disease, Dementia | Not applicable | Completed | Case Comprehensive Cancer Center | 72 | 2013-03-07 | 2019-10-29 |
| Impact of the PET in the Diagnosis Strategy of FUO or Inflammatory Syndrome in Immunocompetent Patients FUO-TEP TEP - Fever | Not applicable | Completed | University Hospital, Limoges | 116 | 2008-05-01 | 2025-07-20 |
| Procalcitonin in Fever of Unknown Etiology antibiotic discontinuation - Fever | Not applicable | Terminated | Changi General Hospital | 90 | 2007-01-01 | 2007-11-20 |
| Immediate vs. Deferred Empirical Antifungal Treatment With Voriconazole In Neutropenic Patients voriconazole (Vfend) - Possible Fungal Infection | Phase 3 | Completed | Pfizer | 147 | 2005-01-01 | 2012-01-19 |
Showing 20 of 21. Sign in to see all of them.
Fever (5) · Neutropenia (2) · Bacterial Infections (1) · Chest Pain (1) · Dementia (1) · Diabetes Mellitus (1) · Dyspnea (1) · Endocarditis (1) · Heart Diseases (1) · Heart Failure (1) · Hematologic Neoplasms (1) · Hypertension (1) · Immunoglobulin G4-Related Disease (1) · Inflammation (1)
Body Temperature Changes (21) · Pathological Conditions, Signs and Symptoms (21) · Signs and Symptoms (21) · Fever (16) · Infections (5) · Cardiovascular Diseases (3) · Pathologic Processes (3) · Agranulocytosis (2) · Bacterial Infections and Mycoses (2) · Central Nervous System Diseases (2) · Cytopenia (2) · Heart Diseases (2) · Hematologic Diseases (2) · Hemic and Lymphatic Diseases (2) · Leukocyte Disorders (2)
Magnetic Resonance Imaging (2) · Positron-Emission Tomography (2) · Observation (1) · Single Photon Emission Computed Tomography Computed Tomography (1) · Tomography, Emission-Computed (1) · Tomography, Emission-Computed, Single-Photon (1) · Tomography, X-Ray Computed (1) · Tuberculin Test (1) · Voriconazole (1) · gallium citrate (1) · tetraethylpyrazine (1)
Beijing Friendship Hospital (2) · Assiut University (1) · Carina Mari Aparici (1) · Case Comprehensive Cancer Center (1) · Changi General Hospital (1) · Fadoi Foundation, Italy (1) · Kasey Phifer (1) · National Institute of Cardiology, Warsaw, Poland (1) · Pfizer (1) · Post Graduate Institute of Medical Education and Research, Chandigarh (1) · Rovere Querini Patrizia (1) · Sorveglianza Epidemiologica Infezioni Fungine Emopatie Maligne (1) · Tongji Hospital (1) · Universitair Ziekenhuis Brussel (1) · Universitaire Ziekenhuizen KU Leuven (1)
France (3) · Italy (3) · Belgium (2) · China (2) · United States (2) · Australia (1) · Finland (1) · Germany (1) · India (1) · Poland (1) · Singapore (1) · United Kingdom (1)
Carina Mari Aparici, MD (1) · Chao Wang, Doctor (1) · Deba Prasad Dhibar, MD (1) · Hanna Szwed, MD, PhD (1) · Jianxin Song, MD (1) · Kim LY, MD (1) · Laurence Bouillet, PhD (1) · Maciej P Chlebicki, MD (1) · Marjo Renko, PhD, MD (1) · Nathalie Compte, MD, PhD (1) · Pablo Ros, MD, MPH, PhD (1)
PMID 26101020, PMID 35054081, PMID 36307738, PMID 36445676, PMID 36884116, PMID 40828443
P30CA043703 (1)