52 completed, 34 unknown, 19 recruiting, 9 terminated. 83 Not applicable, 21 Phase 2, 13 Phase 1, 13 Phase 3, 3 Phase 4.
Follow Diathermy: new trials by email Literature Review of Diathermy trials Research Report on Diathermy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Prospective Study of Concurrent Hyperthermia, Chemotherapy and Radiotherapy in Borderline and Locally Advanced Pancreatic Cancer (PANHEAT) Hyperthermia plus neoadjuvant chemotherapy/radiotherapy Arm Description: Hyperthermia plus neoadjuvant chemotherapy (mFOLFIRINOX/nab Paclitaxel) followed by a) surgically resectable: Hyp - Borderline and Locally Advanced Pancreatic Cancer | Not applicable | Not yet recruiting | Fernando Pessoa Canarias University | 60 | 2027-03-31 | 2026-09-24 |
| Thermotherapy for Head and Neck Cancer Patients Thermotherapy, Radiotherapy, Concurrent chemoradiation - Head and Neck Cancer, Oropharyngeal Carcinoma | Phase 1 | Recruiting | Erasmus Medical Center | 30 | 2026-09-01 | 2026-09-02 |
| Hyperthermia Safety Study Uses Temperature Management System to Gently Raise Participant's Body Temperature to a Fever-range Level in a Controlled Setting. Hyperthermia - Safety Study | Not applicable | Enrolling by invitation | Marc Abreu | 20 | 2026-09-01 | 2026-09-21 |
| Permissive Hyperthermia in Acute Brain Injury Temperature < 39,5, Temperature <37.5 - Fever | Not applicable | Active not recruiting | Odense University Hospital | 20 | 2026-04-25 | 2026-07-16 |
| Daily Nitrofurantoin Versus Bladder Fulguration Plus Daily Nitrofurantoin for Women With Recurrent Urinary Tract Infections Electrofulguration (EF), Nitrofurantoin (NF) - Recurrent UTIs, Cystitis Recurrent | Phase 1 | Recruiting | University of Texas Southwestern Medical Center | 104 | 2026-04-06 | 2026-07-23 |
| Acute Effects of Radiofrequency Diathermy in Postpartum Women With Diastasis Abdominis Radiofrequency diathermy (RFD), Sham radiofrequency diathermy ( sham RFD) - Postpartum, Rectus Muscle Diastasis | Not applicable | Recruiting | University of Valencia | 48 | 2026-03-30 | 2026-06-25 |
| Effects of Diagonal Proprioceptive Neuromuscular Facilitation Patterns on Pain and Functional Outcomes in Patients With Knee Osteoarthritis Diagonal Proprioceptive Neuromuscular Facilitation (PNF) Pattern Exercises, Conventional Strength Training Exercises, Heat Therapy - Knee Osteoarthristis, Osteearthritis | Not applicable | Recruiting | University of Karachi | 150 | 2026-02-07 | 2026-02-11 |
| The Sarah Nanotechnology System for Treatment of Advanced Metastatic Solid Tumors Using Hyperthermia. The Sarah Nanotechnology System - intended to deliver thermal energy to malignant cells for the purpose of thermal destruction of these cells in patients with advanced metastatic solid tumors. - Metastatic Solid Tumors, Stage 4 Cancer | Not applicable | Recruiting | New Phase Ltd. | 12 | 2025-12-16 | 2026-05-15 |
| Masseter Muscle Stiffness After Heat Application and Percussion Therapy massage gun, heat treatment - Healthy Participants | Not applicable | Recruiting | University of Zurich | 40 | 2025-11-15 | 2025-11-19 |
| Acute Effects of Hot-Pack Therapy in Low Back Pain Hot-Pack, Sham Pack - Low Back Pain, Back Pain | Not applicable | Not yet recruiting | Erzurum Technical University | 24 | 2025-11-10 | 2025-11-21 |
| Heat and Exercise in Aging as Therapy (HEAT) Heat therapy, High-intensity interval training - Prediabetic State | Not applicable | Recruiting | Texas Tech University | 54 | 2025-11-06 | 2026-06-23 |
| Effects of Battle Rope Training on ROM and Pain in Children With Post Traumatic Elbow Contractures. Battle Rope Training, Stretching and Heat Therapy - Children, Adult | Not applicable | Recruiting | Riphah International University | 42 | 2025-10-29 | 2025-11-25 |
| Feasibility of Total Neoadjuvant Treatment With HYPErthermia in Patients With High-risk Extremity and Trunk Soft Tissue Sarcoma (TNT-HYPE) Doxorubicin, Ifosfamide, Dacarbazine - Sarcoma,Soft Tissue | Phase 2 | Recruiting | Swiss Cancer Institute | 24 | 2025-10-27 | 2025-12-30 |
| A Self-controlled Study of Bleomycin and Pingyangmycin Injection in the Treatment of Plantar Warts Hyperthermia Therapy, Pingyangmycin Injection, Bleomycin injection - Plantar Wart | Phase 4 | Active not recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 200 | 2025-10-01 | 2026-07-02 |
| Modulated Electro-Hyperthermia in Combination With Multimodal Therapy for Locally Advanced Rectal Cancer Hyperthermia - Locally Advanced Rectal Carcinoma | Phase 3 | Recruiting | Shih-Kai Hung | 126 | 2025-09-23 | 2026-01-28 |
| Thermal Therapies in the Treatment of Muscle Injuries Cold water immersion, Hot water immersion, Physiotherapy only - Hamstring Injuries, Hamstring Muscle Repair | Not applicable | Not yet recruiting | Aspetar | 135 | 2025-09-01 | 2025-07-01 |
| Hyperthermia Combined With Immune Checkpoint Inhibitors in the Treatment of Advanced Gastrointestinal Malignancies With Liver Metastases Hyperthermia, Immunotherapy - Gastrointestinal Cancer, Immunotherapy | Phase 2 | Not yet recruiting | China Medical University, China | 40 | 2025-08-15 | 2025-08-12 |
| Analysis of Hyperthermia as an Adjunctive Treatment to Evidence-based Clinical Intervention in Subjects With Bursitis: a Double-blind Randomized Clinical Trial Hyperthermia, Physical Exercise, Stretching - Bursitis, Hyperthermia | Not applicable | Not yet recruiting | University of Malaga | 120 | 2025-08-01 | 2025-08-01 |
| Analysis of Hyperthermia as an Adjunctive Treatment to Evidence-based Clinical Intervention in Subjects With Plantar Fasciitis: a Double-blind Randomized Clinical Trial Hyperthermia, Physical Exercise, Stretching - Plantar Fascia, Hyperthermia | Not applicable | Not yet recruiting | University of Malaga | 64 | 2025-08-01 | 2025-08-05 |
| Outcomes of Posterior Urethral Valve Fulguration Fulguration - Posterior Urethral Valve | Not yet recruiting | Assiut University | 35 | 2025-05-01 | 2025-03-10 |
Showing 20 of 133. Sign in to see all of them.
Hyperthermia (40) · Fever (9) · Low Back Pain (8) · Sarcoma (8) · Uterine Cervical Neoplasms (7) · Breast Neoplasms (6) · Colonic Neoplasms (5) · Head and Neck Neoplasms (5) · Ovarian Neoplasms (5) · Prostatic Neoplasms (5) · Rectal Neoplasms (5) · Neoplasm Metastasis (4) · Neoplasms (4) · Carcinoma, Hepatocellular (3) · Intervertebral Disc Displacement (3)
University of Erlangen-Nürnberg Medical School (6) · Foundation University Islamabad (5) · Indiana University (3) · Maria Sklodowska-Curie National Research Institute of Oncology (3) · Mark Dewhirst (3) · Shin Kong Wu Ho-Su Memorial Hospital (3) · The University of Texas Health Science Center, Houston (3) · University of Malaga (3) · University of Oregon (3) · Ain Shams University (2) · Camilo Jose Cela University (2) · Erasmus Medical Center (2) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (2) · Kafrelsheikh University (2) · Riphah International University (2)
United States (44) · Germany (10) · Spain (10) · Pakistan (7) · Egypt (5) · Taiwan (5) · China (4) · Netherlands (4) · Poland (4) · Turkey (Türkiye) (4) · France (3) · Switzerland (3) · Austria (2) · India (2) · Italy (2)
Joan M.C. Bull, MD (3) · Douglas R Seals, PhD (2) · Ellen L. Jones, MD, PhD (2) · H. I. Robins, MD, PhD (2) · Michiel Kroesen, MD, Dr. (2) · Muhammad Osama, PhD* (2) · Oliver Ott, MD (2) · Vratislav Strnad, MD (2) · Aamer Naeem, PhD* (1) · Aftab Ahmed Mirza Baig, PhD (1) · Angeles Secord, MD (1)
PMID 27270841, PMID 18474099, PMID 18608594, PMID 19994492, PMID 20434400, PMID 22925164, PMID 23076403, PMID 24399113, PMID 24586242, PMID 24747207, PMID 25144817, PMID 25786484, PMID 26206681, PMID 27286178, PMID 27418688, PMID 28167186, PMID 29450452, PMID 29451806, PMID 30113522, PMID 30274699, PMID 30335579, PMID 30390114, PMID 31074654, PMID 31580698, PMID 31772984, PMID 31956433, PMID 33476595, PMID 33805731, PMID 34111245, PMID 34666214, PMID 36045358, PMID 38568718, PMID 39283227, PMID 39437435, PMID 39920700, PMID 40143467, PMID 40465937, PMID 40740146, PMID 41264372, PMID 41525928, PMID 41702454, PMID 42035475, PMID 42548151
2025 (1), M01RR000030 (1), P30CA006516 (1), P30CA016672 (1), P30DK097512 (1), R01AG089307 (1), R01CA122276 (1), R01DK140224 (1)