94 completed. 94 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 94 | Completed 94 |
Follow Appendicitis: new trials by email Literature Review of Appendicitis trials Research Report on Appendicitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Laparoscopic vs Open Appendectomy Laparoscopic appendectomy, Open Appendectomy - Acute Appendicitis, Superficial SSI | Not applicable | Completed | Quaid-e-Azam Medical College | 276 | 2026-01-24 | 2026-09-25 |
| Differences In Microbiota Profiles Of Pediatric Appendicitis Cases Appendectomy - Appendicitis Acute, Disbiosis | Not applicable | Completed | Istanbul University | 50 | 2025-08-18 | 2026-10-06 |
| Evaluating the Outcome of Surgical Clip Versus Ligatures in Securing Base of Appendix in Laparoscopic Appendicectomy. single polymeric clip (XXL Click'aV Plus, Grena), suture ligature - Appendicitis (Diagnosis) | Not applicable | Completed | Universiti Sains Malaysia | 64 | 2025-07-01 | 2026-07-08 |
| Ciprofol Based on Total Intravenous Anesthesia During Pediatric Laparoscopic Surgery Ciprofol, Propofol - Pediatric Hernia, Laparoscopic Surgery | Not applicable | Completed | Tongji Hospital | 86 | 2025-03-09 | 2025-12-29 |
| Efficacy of Transversus Abdominis Plane Block in Alleviating Acute Appendicitis Transversus Abdominis Plane Blockage - Acute Appendicitis | Not applicable | Completed | Ankara City Hospital Bilkent | 105 | 2024-05-08 | 2026-06-04 |
| Aromatherapy Versus Acupressure: Impact on Postoperative Pain and Sleep Quality in Pediatric Abdominal Surgery Patients Accupressure, Aromatherapy inhaler - Appendicitis, Hernia | Not applicable | Completed | Mansoura University | 100 | 2024-04-01 | 2025-09-05 |
| Safety & Feasibility of PERIsign System in Demonstrating Involuntary Muscle Defense as a Sign of Peritonitis in Subjects With Appendicitis PERIsign examination - Appendicitis Acute, Appendicitis | Not applicable | Completed | STB INN AB | 40 | 2024-03-15 | 2024-09-19 |
| The Effect of Kinesio Taping in Pediatric Surgery Kinesio taping - Appendicitis, Surgery | Not applicable | Completed | KTO Karatay University | 68 | 2024-02-25 | 2024-04-03 |
| Effect of Modified ERAS Protocol on Clinical Outcomes in Pediatric Patients With Appendectomy Education and counselling, Avoiding the use of nasogastric catheters, drains and urinary catheters, Stimulation of intestinal motility in the postoperative period - ERAS, Surgery | Not applicable | Completed | Karadeniz Technical University | 82 | 2023-10-01 | 2025-10-03 |
| "Stump-First" Approach in Laparoscopic Appendectomy Classic Approach in Laparoscopic Appendectomy, Stump first Approach in Laparoscopic Appendectomy - Acute Appendicitis, Acute Appendicitis with Appendix Abscess | Not applicable | Completed | Izmir City Hospital | 78 | 2023-04-01 | 2025-03-27 |
| Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure (CASA RELAX) - Atrium Health Antibiotic - Appendicitis Surgery | Not applicable | Completed | Wake Forest University Health Sciences | 268 | 2023-03-02 | 2025-11-03 |
| Cold Therapy for Pediatric Appendectomy Cold Therapy, Standard of Care - Appendicitis | Not applicable | Completed | Boston Children's Hospital | 52 | 2021-12-22 | 2026-04-28 |
| Restricted or Liberal Antibiotics After Appendectomy - Denver Health Restricted Duration of SOC Antibiotic Use, Liberal Duration of SOC Antibiotic Use - Appendicitis | Not applicable | Completed | Denver Health and Hospital Authority | 657 | 2021-11-01 | 2026-06-30 |
| Online Field Test of an Appendicitis Decision Support Tool Appendicitis Decision Support Tool, Control Infographic - Appendicitis Acute | Not applicable | Completed | University of Washington | 194 | 2021-10-06 | 2022-02-02 |
| Evaluation of One Day Discharge After Laparoscopic Appendectomy for Uncomplicated Appendicitis in Children. Laparoscopic Appendectomy - Appendicitis Acute | Not applicable | Completed | Miro Jukić | 180 | 2021-10-02 | 2022-07-20 |
| Low vs Medium Pressure Pneumoperitoneum Laparoscopic appendectomy - Appendicitis Acute | Not applicable | Completed | University Children's Hospital, Zurich | 250 | 2021-09-27 | 2026-07-30 |
| TAP Block Versus Local Anesthesia Wound Infiltration for Postoperative Pain Relief After Appendicectomy in Children Levobupivacaine Hydrochloride 2.5 MG/ML - Appendicitis Acute, Pediatrics | Not applicable | Completed | Centre Hospitalier Universitaire de Besancon | 110 | 2021-07-30 | 2025-04-23 |
| Ultrasound Guided Rectus Sheath Block and Transversus Abdominis Plane Block Dexmedetomidine - Cholecystitis, Appendicitis | Not applicable | Completed | Assiut University | 90 | 2021-04-01 | 2023-04-20 |
| Which Trocar Access Site Should We Use in Laparoscopic Appendectomy? Only different trocar sites - Pain | Not applicable | Completed | Inonu University | 140 | 2021-02-01 | 2022-04-05 |
| Effect of Intravenous Lignocaine Infusion on Intraoperative End Tidal Desflurane Concentration Requirements Lignocaine, Placebo - Cholelithiases, Appendicitis | Not applicable | Completed | Universiti Kebangsaan Malaysia Medical Centre | 48 | 2021-01-21 | 2023-10-03 |
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Pain (6) · Abscess (3) · Pain, Postoperative (3) · Agnosia (2) · Cholelithiasis (2) · Wound Infection (2) · Abdomen, Acute (1) · Abdominal Abscess (1) · Abdominal Pain (1) · Acute Disease (1) · Acute Pain (1) · Anxiety Disorders (1) · Charcot-Marie-Tooth disease, Type 1C (1) · Cholecystitis (1)
Cecal Diseases (94) · Digestive System Diseases (94) · Gastroenteritis (94) · Intestinal Diseases (94) · Gastrointestinal Diseases (93) · Infections (93) · Intraabdominal Infections (93) · Pathological Conditions, Signs and Symptoms (23) · Neurologic Manifestations (13) · Pathologic Processes (13) · Signs and Symptoms (13) · Pain (5) · Biliary Tract Diseases (4) · Inflammation (4) · Postoperative Complications (4)
Appendectomy (10) · Metronidazole (4) · Amoxicillin-Potassium Clavulanate Combination (3) · Anti-Bacterial Agents (2) · Ceftriaxone (2) · Ciprofloxacin (2) · Drainage (2) · Ertapenem (2) · Open Abdomen Techniques (2) · Oxygen (2) · Saline Solution (2) · Therapeutic Irrigation (2) · (2-(1R)-1-cyclopropyl)ethyl-6-isopropyl-phenol (1) · Acetaminophen (1) · Amoxicillin (1)
Children's Mercy Hospital Kansas City (6) · Mansoura University (4) · Bakirkoy Dr. Sadi Konuk Research and Training Hospital (2) · Fatih Sultan Mehmet Training and Research Hospital (2) · University of Washington (2) · Wake Forest University Health Sciences (2) · Zagazig University (2) · Ankara City Hospital Bilkent (1) · Assistance Publique - Hôpitaux de Paris (1) · Assiut University (1) · Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (1) · Beaumont Hospital (1) · Bezmialem Vakif University (1) · Bispebjerg Hospital (1) · Boston Children's Hospital (1)
United States (24) · Turkey (Türkiye) (14) · Egypt (7) · France (5) · South Korea (4) · China (3) · Croatia (3) · Finland (3) · Malaysia (3) · Pakistan (3) · Canada (2) · Israel (2) · Sweden (2) · Australia (1) · Bosnia and Herzegovina (1)
Shawn D St. Peter, MD (4) · David R Flum, MD, MPH (2) · Abut Kebudi, Prof. (1) · Ahmet Burak Erdem, Assoc. Prof. (1) · Alexander V Sazhin, Prof. (1) · Andrew Kepner, MD (1) · Anupam B Kharbanda, MD, MSc (1) · Arnold K Hill (1) · Arthur Rawlings, MD (1) · Asmaa S.A. El Malah, PhD (1) · Benedict Taylor, MD (1) · Bo Seung Kang, MD (1) · Brant T Heniford, M.D. (1)
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