15 completed, 10 unknown, 3 terminated, 2 recruiting. 9 Not applicable, 8 Phase 4, 6 Phase 1, 3 Phase 2, 2 Phase 3.
Follow Analgesics: new trials by email Literature Review of Analgesics trials Research Report on Analgesics
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Natural History of Depression, Bipolar Disorder and Suicide Risk Behavioral Symptoms, Suicide | Recruiting | National Institute of Mental Health (NIMH) | 500 | 2024-09-09 | 2026-11-09 | |
| U/S Guided Rhomboid Intercostal Block Combined With Sub-Serratus Plane Block vs Type 2 Pectoral Nerve Block U/S guided Type 2 Pectoral Nerve Block, U/S guided RIB combined with the sub-serratus plane block (RISS) - Breast Neoplasm Female, Analgesics | Not applicable | Completed | National Cancer Institute, Egypt | 69 | 2023-06-01 | 2024-07-22 |
| Comparison of 2 Different Methods in Infraclavicular Block dexamethasone - Postoperative Pain, Nerve Block | Unknown | Ankara City Hospital Bilkent | 60 | 2023-03-10 | 2024-08-06 | |
| Opioid Sparing Anesthesia in Cervical Spine Surgery ketamine-lidocaine, Remifentanil - Pain, Postoperative, Pain, Acute | Not applicable | Unknown | Evangelismos Hospital | 60 | 2022-11-01 | 2023-02-08 |
| Opioid Sparing Anesthesia in Lumbar Spine Surgery dexmedetomidine-ketamine-lidocaine, Remifentanil - Pain, Postoperative, Pain, Acute | Not applicable | Unknown | Aretaieion University Hospital | 60 | 2022-08-01 | 2022-10-31 |
| Opioid-free Anesthesia in Thyroidectomies dexmedetomidine-ketamine-lidocaine (DKL), remifentanil infusion - Pain, Post Operative, Pain, Acute | Not applicable | Unknown | Aretaieion University Hospital | 60 | 2022-03-07 | 2023-04-26 |
| Rescue Quadratus Lumborum Blocks for Post-cesarean Pain Saline, Bupivacaine, Dexamethasone - Morphine, Analgesics | Phase 4 | Withdrawn | The University of Texas Health Science Center, Houston | 2022-01-01 | 2023-11-03 | |
| Opioid-free Anesthesia in Laparoscopic Cholecystectomies ketamine-lidocaine-dexmedetomidine, fentanyl - Pain, Postoperative, Pain, Acute | Not applicable | Unknown | Aretaieion University Hospital | 70 | 2021-10-11 | 2023-02-24 |
| Drug-drug Interaction Study of Lemborexant as an Adjunctive Treatment for Buprenorphine/Naloxone for Opioid Use Disorder Lemborexant, Placebo, Buprenorphine-naloxone - Drug Interaction, Analgesics | Phase 1 / Phase 2 | Completed | Virginia Commonwealth University | 18 | 2021-05-03 | 2024-11-13 |
| Pregabalin vs. Gabapentin on Reducing Opioid Usage Pregabalin 50mg, Gabapentin 300mg, Neither Pregabalin nor Gabapentin - Analgesics, Gabapentin | Phase 4 | Completed | CAMC Health System | 109 | 2021-04-12 | 2026-01-06 |
| Opioid-free Anesthesia With a Mixture of Dexmedetomidine-lidocaine-ketamine ketamine-lidocaine-dexmedetomidine, fentanyl - Pain, Postoperative, Pain, Acute | Not applicable | Unknown | Aretaieion University Hospital | 60 | 2021-04-01 | 2022-10-24 |
| EFFECT - EFFectiveness of ESPB (Erector Spinae Plane Block) in Laparoscopic Cοlectomies Trial Ropivacaine injection - Pain, Postoperative, Acute Pain | Not applicable | Unknown | Democritus University of Thrace | 40 | 2021-01-01 | 2021-05-10 |
| Lidocaine and Magnesium and Ketamine in Gynecological Surgery lidocaine-magnesium infusion, lidocaine-ketamine infusion, lidocaine infusion - Pain, Postoperative, Pain, Acute | Not applicable | Unknown | Aretaieion University Hospital | 90 | 2020-11-14 | 2022-10-27 |
| Natural Killer Cell (CYNK-001) IV Infusion or IT Administration in Adults With Recurrent GBM CYNK001-IV, CYNK001-IT - Astrocytoma, Grade IV, Giant Cell Glioblastoma | Phase 1 | Terminated | Celularity Incorporated | 3 | 2020-10-01 | 2022-08-10 |
| Natural Killer Cell (CYNK-001) Infusions in Adults With COVID-19 CYNK-001 - Coronavirus, Coronavirus Infection | Phase 1 / Phase 2 | Terminated | Celularity Incorporated | 7 | 2020-09-02 | 2026-06-26 |
| Addition of Buprenorphine to Paracervical Block for Pain Control During Osmotic Dilator Insertion Buprenorphine 0.15 MG, Lidocaine 1% Injectable Solution - Procedural Pain, Buprenorphine | Phase 4 | Completed | University of California, San Diego | 57 | 2020-05-28 | 2023-08-01 |
| Natural Killer Cell (CYNK-001) Infusions in Adults With Multiple Myeloma CYNK-001 - Multiple Myeloma, Neoplasm, Plasma Cell | Phase 1 | Unknown | Celularity Incorporated | 29 | 2020-05-12 | 2023-02-16 |
| Post-cesarean Analgesia With Epidural Morphine Following Epidural 2-chloroprocaine 2% lidocaine with 1:200,000 epinephrine and epidural morphine, 3% 2-chloroprocaine and epidural morphine - Physiological Effect of Drugs, Morphine | Phase 4 | Completed | The University of Texas Health Science Center, Houston | 44 | 2020-05-11 | 2022-05-26 |
| Natural Killer Cell (CYNK-001) Infusions in Adults with AML CYNK-001 - Leukemia, Leukemia, Myeloid | Phase 1 | Terminated | Celularity Incorporated | 27 | 2020-03-12 | 2024-12-12 |
| Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients Dexmedetomidine Hydrochloride Group - Delirium, Cognitive Dysfunction | Phase 4 | Recruiting | Sunnybrook Health Sciences Centre | 2400 | 2019-12-01 | 2025-12-01 |
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Pain, Postoperative (14) · Acute Pain (10) · Agnosia (7) · Chronic Pain (7) · Nociceptive Pain (6) · Pain (4) · Neuralgia (3) · Postoperative Complications (3) · Delirium (2) · Hematologic Diseases (2) · Immune System Diseases (2) · Mental Disorders (2) · Neoplasm, Residual (2) · Neoplasms (2) · Neoplasms by Histologic Type (2)
Pathological Conditions, Signs and Symptoms (25) · Neurologic Manifestations (21) · Signs and Symptoms (21) · Pathologic Processes (17) · Pain (16) · Postoperative Complications (13) · Nervous System Diseases (10) · Neurobehavioral Manifestations (8) · Perceptual Disorders (7) · Neoplasms (3) · Neoplasms by Site (3) · Neuromuscular Diseases (3) · Peripheral Nervous System Diseases (3) · Behavior (2) · Hemic and Lymphatic Diseases (2)
Acetaminophen (3) · Dexamethasone (3) · Dexmedetomidine (3) · Fentanyl (3) · Lidocaine (3) · Control Groups (2) · Gabapentin (2) · Ketamine (2) · Ondansetron (2) · Remifentanil (2) · Sodium Chloride (2) · Analgesics (1) · Aspirin (1) · Bupivacaine (1) · Buprenorphine (1)
Aretaieion University Hospital (5) · Celularity Incorporated (4) · Samsung Medical Center (2) · The University of Texas Health Science Center, Houston (2) · Alza Corporation, DE, USA (1) · Ankara City Hospital Bilkent (1) · Azienda Ospedaliera S. Maria della Misericordia (1) · CAMC Health System (1) · Copenhagen University Hospital, Rigshospitalet (1) · Democritus University of Thrace (1) · Evangelismos Hospital (1) · Johnson & Johnson Consumer and Personal Products Worldwide (1) · Medical University Innsbruck (1) · NEMA Research, Inc. (1) · National Cancer Institute, Egypt (1)
United States (10) · Greece (7) · Canada (2) · South Korea (2) · Austria (1) · China (1) · Denmark (1) · Egypt (1) · France (1) · Italy (1) · Turkey (Türkiye) (1)
Kassiani Theodoraki (3) · Linden Lee, MD (2) · Adrian Kilcoyne, MD (1) · Barry T Reece, MS, MBA (1) · Ciro Paolillo, Dr (1) · Corey Casper, MD MPH (1) · Elizabeth D Ballard, Ph.D. (1) · Esma M Simsek, M.D. (1) · Frederick G Moeller, MD (1) · Jessica Williams, BS (1) · Jon Gamble, MD (1) · Jun Li (1)
PMID 17877652, PMID 18380946, PMID 33849856, PMID 36534717, PMID 40884325
2014 (1), UG1DA050207 (1)