65 completed, 25 unknown, 21 recruiting, 20 terminated. 50 Not applicable, 30 Phase 2, 16 Phase 3, 10 Phase 1, 6 Phase 4.
Follow Adenomatous Polyps: new trials by email Literature Review of Adenomatous Polyps trials Research Report on Adenomatous Polyps
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Safety Study of ST316 in Participants With Familial Adenomatous Polyposis (FAP). ST316 IV - Familial Adenomatous Polyposis (FAP) | Phase 1 | Not yet recruiting | Sapience Therapeutics | 40 | 2027-01-04 | 2026-08-12 |
| Safety Study for the Use of Rapamycin in Children With Familial Adenomatous Polyposis Rapamycin - Familial Adenomatous Polyposis | Phase 2 | Not yet recruiting | University Hospital, Toulouse | 25 | 2026-09-01 | 2026-05-08 |
| Recurrence After Gastric and Intestinal Polyp Resection Gastric Polyps, Intestinal Polyps | Not yet recruiting | LanZhou University | 2000 | 2026-07-26 | 2026-06-09 | |
| Evaluation of the Ileo-anal Pouch in FAP (ENDOPOL) Chromoendoscopy (Indigo Carmine), Virtual Chromoendoscopy - Familial Adenomatous Polyposis (FAP), Pouches, Ileoanal | Not applicable | Recruiting | London North West Healthcare NHS Trust | 50 | 2026-07-09 | 2026-07-24 |
| Trial of Exercise Therapy in Familial Adenomatous Polyp (FAP) Exercise Therapy - Familial Adenomatous Polyposis | Not applicable | Recruiting | University of Michigan Rogel Cancer Center | 32 | 2026-05-13 | 2026-05-19 |
| An Investigational Drug (TPST-1495) in Patients With Familial Adenomatous Polyposis Biopsy Procedure, Biospecimen Collection, EP2/EP4 Antagonist TPST-1495 - Colorectal Carcinoma, Familial Adenomatous Polyposis | Phase 2 | Recruiting | National Cancer Institute (NCI) | 38 | 2026-03-31 | 2026-09-14 |
| Impact of Prior Identification and Education of Patients Requiring a Digestive Stoma for Fecal Diversion preoperative stoma identification and education - Colorectal Anastomosis, Endometrial | Not applicable | Not yet recruiting | Assistance Publique Hopitaux De Marseille | 100 | 2026-03-01 | 2025-11-18 |
| Safety and Efficacy of Tegavivint in Patients With Metastatic Colorectal Carcinoma Tegavivint - Metastatic Colorectal Carcinoma (mCRC), Colorectal Cancer (CRC) | Phase 1 / Phase 2 | Recruiting | HonorHealth Research Institute | 126 | 2026-02-17 | 2026-03-11 |
| ColoMaia II Software to Support Lesion Detection During Colonoscopy ColoMaia II software, Standard colonoscopy - Colonic Polyps, Adenomatous Polyps | Not applicable | Completed | MAIA Labs s.r.o. | 600 | 2025-11-11 | 2026-06-18 |
| Testing for Safety and Colorectal Cancer Preventive Effects of ONC201 Biopsy Procedure, Biospecimen Collection, Colonoscopy - Colorectal Adenomatous Polyp, Colorectal Carcinoma | Phase 1 | Recruiting | National Cancer Institute (NCI) | 36 | 2025-10-06 | 2026-10-15 |
| Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis eRapa (encapsulated rapamycin), Placebo - Familial Adenomatous Polyposis (FAP) | Phase 3 | Recruiting | Rapamycin Holdings Inc. | 168 | 2025-07-18 | 2026-06-02 |
| Ten Versus Fifteen Centimeter Pouch in IPAA Surgery 10 cm pouch, 15 cm pouch - Ulcerative Colitis, Familial Adenomatous Polyposis | Not applicable | Recruiting | Odense University Hospital | 120 | 2025-07-03 | 2025-07-09 |
| Linked-Color Imaging Versus Indigo Carmine Pump Spraying on the Colorectal Adenoma Detection Rate Chromoendoscopy with indigo carmine solution spray, Linked-color imaging endoscopy - Colonic Polyps, Adenomatous Polyps | Not applicable | Recruiting | Shandong University | 352 | 2025-04-08 | 2025-05-07 |
| Artificial Intelligence-assisted Colonoscopy in the Detection and Characterization of Colorectal Lesions Colonoscopy - Colorectal Cancer (CRC), Adenomatous Polyposis | Not applicable | Recruiting | Instituto do Cancer do Estado de São Paulo | 1000 | 2025-02-01 | 2026-06-23 |
| Microbial and Environmental Factors Associated With Polyps Development in Familial Adenomatous Polyposis (MicrobEnvironment in FAP) Sampling of feces and duodenal fluids - Familial Adenomatous Polyposis | Recruiting | Hospices Civils de Lyon | 100 | 2024-12-17 | 2026-05-27 | |
| A Comparison of the Resection Rate for Hot and Cold Snare Polypectomy of Colorectal Polyps (10-15 Mm) Active Comparator: Hot Snare Polypectomy, Experimental: Cold Snare Polypectomy - Adenomatous Polyps | Not applicable | Recruiting | Technical University of Munich | 850 | 2024-11-05 | 2024-11-12 |
| Investigation of β-hydroxybutyrate Supplementation as Chemoprevention in Familial Adenomatous Polyposis R-1,3-Butanediol (10G-A), R-1,3-Butanediol (20G-A), R-1,3-Butanediol (30G-A) - FAP, Familial Adenomatous Polyposis | Not applicable | Enrolling by invitation | Abramson Cancer Center at Penn Medicine | 20 | 2024-09-20 | 2026-09-16 |
| Detection of Ileoanal Pouch/Reservoir Adenomas Adenomas detection rate with the different observation methods - Adenomatous Polyps | Unknown | Jean Christophe Saurin | 40 | 2024-09-09 | 2023-09-25 | |
| Chemopreventive Effect of Combination of Celecoxib and Metformin in Patients With Familial Adenomatous Polyposis celecoxib monotherapy, celecoxib and metformin combination - Familial Adenomatous Polyposis | Phase 3 | Unknown | Yonsei University | 28 | 2024-08-13 | 2024-08-09 |
| Familial Adenomatous Poliposys Italian Network (Rete Italiana Poliposi Adenomatosa Familiare) Familial Adenomatous Polyposis (FAP), Attenuated Familial Adenomatous Polyposis (AFAP) | Active not recruiting | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | 1500 | 2024-05-13 | 2026-03-10 |
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Adenomatous Polyposis Coli (92) · Colorectal Neoplasms (40) · Adenoma (16) · Colonic Neoplasms (15) · Colonic Polyps (13) · Colitis, Ulcerative (11) · Polyps (11) · Rectal Neoplasms (9) · Precancerous Conditions (8) · Colorectal Neoplasms, Hereditary Nonpolyposis (7) · Crohn Disease (5) · Desmoid Tumors (5) · Duodenal Neoplasms (5) · Neoplasms (5)
Neoplasms, Glandular and Epithelial (146) · Neoplasms by Histologic Type (145) · Neoplasms (141) · Adenoma (130) · Colonic Diseases (117) · Digestive System Diseases (117) · Gastrointestinal Diseases (117) · Neoplasms by Site (117) · Digestive System Neoplasms (116) · Intestinal Diseases (116) · Intestinal Neoplasms (115) · Gastrointestinal Neoplasms (114) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (93) · Intestinal Polyposis (93) · Genetic Diseases, Inborn (91)
Colonoscopy (8) · Celecoxib (7) · Biopsy (5) · Eflornithine (4) · Endoscopy (4) · Sulindac (4) · Aspirin (3) · Cholecalciferol (3) · Curcumin (3) · Erlotinib Hydrochloride (3) · Sirolimus (3) · Specimen Handling (3) · Blood Specimen Collection (2) · Calcium Carbonate (2) · Eicosapentaenoic Acid (2)
National Cancer Institute (NCI) (12) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (4) · Centre hospitalier de l'Université de Montréal (CHUM) (3) · Charite University, Berlin, Germany (3) · Fondazione IRCCS Istituto Nazionale dei Tumori, Milano (3) · Janssen Research & Development, LLC (3) · M.D. Anderson Cancer Center (3) · S.L.A. Pharma AG (3) · Vanderbilt University Medical Center (3) · Yonsei University (3) · Cancer Prevention Pharmaceuticals, Inc. (2) · Changhai Hospital (2) · Dartmouth-Hitchcock Medical Center (2) · Istituto Clinico Humanitas (2) · Johns Hopkins University (2)
United States (65) · China (12) · Italy (11) · Netherlands (11) · France (10) · Germany (10) · Canada (9) · Puerto Rico (9) · United Kingdom (8) · Spain (7) · South Korea (6) · Denmark (5) · Belgium (4) · Israel (4) · Australia (3)
Daniel von Renteln (3) · Niloy J Samadder (3) · Amit Rastogi, MD (2) · Chang Kyun Lee, MD, PhD (2) · Gary Shangold, MD (2) · Kefeng Ding, MD (2) · M. Peter Lance, MD (2) · Marco Vitellaro, MD (2) · Nicholas J West, MB BS FRCS (2) · Revital Kariv, MD (2) · Alessandro Repici, MD (1) · Alexander G Raufi, MD (1)
PMID 37119510, PMID 28192823, PMID 28970290, PMID 29802852, PMID 34289971, PMID 12621133, PMID 17551129, PMID 18378608, PMID 18541589, PMID 19258546, PMID 19861511, PMID 19923375, PMID 20018966, PMID 20056649, PMID 20234350, PMID 20332274, PMID 20348368, PMID 20516268, PMID 20685491, PMID 21084270, PMID 21724580, PMID 21762907, PMID 21802078, PMID 21889137, PMID 21899713, PMID 22149065, PMID 22808053, PMID 22964475, PMID 23022496, PMID 23041328, PMID 23060037, PMID 23114473, PMID 23170065, PMID 23399518, PMID 23582472, PMID 23919274, PMID 24014734, PMID 24166893, PMID 24245549, PMID 25070320, PMID 25329821, PMID 25792707, PMID 26126162, PMID 26156248, PMID 26404953, PMID 26465985, PMID 26528500, PMID 27002448, PMID 27094489, PMID 27474021
P30CA015083 (3), P30CA068485 (3), N01CN00042 (2), N01CN35160 (2), P30CA016672 (2), P30CA060553 (2), UG1CA242632 (2), 2019 (1), 2023 (1), N01CN35157 (1), P01CA041108 (1), P01CA073992 (1), P30CA006973 (1), P30CA014520 (1), P30CA023074 (1)