35 completed. 35 Phase 2, 8 Phase 3, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 35 | Completed 35 |
| Phase 3 | 8 | Completed 8 |
| Phase 1 | 4 | Completed 4 |
Follow Abdominal Pain: new trials by email Literature Review of Abdominal Pain trials Research Report on Abdominal Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Efficacy and Safety of CIN-102 (Deudomperidone) in Adult Subjects With Idiopathic Gastroparesis. CIN-102 Dose 15mg, Placebo, CIN-102 Dose 10mg - Idiopathic Gastroparesis | Phase 2 | Completed | CinDome Pharma, Inc. | 416 | 2025-01-29 | 2026-07-13 |
| Study of Hesperidin Therapy on COVID-19 Symptoms (HESPERIDIN) Hesperidin, Placebo - Covid19, Anosmia | Phase 2 | Completed | Montreal Heart Institute | 216 | 2021-02-18 | 2022-04-08 |
| Staccato Granisetron® (AZ 010) for the Treatment of Cyclic Vomiting Syndrome 3mg AZ-010, 1mg AZ010, Staccato Placebo - Cyclic Vomiting Syndrome | Phase 2 | Completed | Alexza Pharmaceuticals, Inc. | 150 | 2021-02-05 | 2025-06-11 |
| A Study of MD-7246 to Treat Abdominal Pain in Patients With Diarrhea-predominant Irritable Bowel Syndrome MD-7246, Placebo - Irritable Bowel Syndrome With Diarrhea (IBS-D) | Phase 2 | Completed | Ironwood Pharmaceuticals, Inc. | 515 | 2019-05-01 | 2021-03-12 |
| Tolerability, Pharmacokinetics, and Efficacy of APD371 in Participants With Crohn's Disease Experiencing Abdominal Pain Olorinab - Crohn's Disease, Abdominal Pain | Phase 2 | Completed | Arena Pharmaceuticals | 14 | 2017-07-19 | 2021-11-02 |
| Analgesic Efficacy of Dexmedetomidine Added to Fentanyl in PCEA TEA+DEX, TEA - Abdominal Pain, Abdominal Cancer | Phase 2 / Phase 3 | Completed | South Egypt Cancer Institute | 90 | 2017-06-30 | 2020-03-23 |
| The Probiotic Study: Using Bacteria to Calm Your Mind Lactobacillus rhamnosus - Anxiety, Abdominal Pain | Phase 2 | Completed | Nancy Zucker | 9 | 2016-11-08 | 2026-06-10 |
| Study of a Monoclonal Antibody KHK4083 in Moderate Ulcerative Colitis KHK4083, Placebo - Ulcerative Colitis, Digestive System Diseases | Phase 2 | Completed | Kyowa Kirin, Inc. | 66 | 2016-06-01 | 2024-04-26 |
| Bifidobacterium Infantis M-63 Improves Mental Health in Irritable Bowel Syndrome Developed After a Major Flood Disaster Probiotics M-63, Control group - Irritable Bowel Syndrome, Abdominal Pain | Phase 2 / Phase 3 | Completed | Universiti Sains Malaysia | 53 | 2015-09-01 | 2017-10-24 |
| Comparing a 182mg Colon-targeted-delivery Peppermint Oil Capsule (Tempocol-ColoPulse®) and a 182mg Enteric-coated Peppermint Oil Capsule (Tempocol®), a Pharmacokinetic Study Menthae piperitae aetheroleum/peppermint oil (enteric coated capsule), Menthae piperitae aetheroleum/peppermint oil (colon-targeted-delivery capsule) - Irritable Bowel Syndrome, Abdominal Pain | Phase 2 | Completed | Maastricht University Medical Center | 8 | 2015-03-01 | 2022-01-24 |
| Probiotic Supplementation Among Adults With Recurrent Gastrointestinal Symptoms Probiotic dietary supplement (Trenev Trio®), placebo - Gastrointestinal Symptoms, Bloating | Phase 2 / Phase 3 | Completed | University of Maryland, Baltimore | 80 | 2014-12-01 | 2021-09-14 |
| Effect of TU-100 in Patients With Irritable Bowel Syndrome (IBS) Daikenchuto (TU-100), Placebo - Irritable Bowel Syndrome, Digestive System Diseases | Phase 1 / Phase 2 | Completed | Tsumura USA | 40 | 2013-08-01 | 2016-06-13 |
| The Analgesic Efficacy of Δ9-THC (Namisol®) in Patients With Persistent Postsurgical Abdominal Pain Tetrahydrocannabinol, Placebo - Postsurgical Pain, Abdominal Pain | Phase 2 | Completed | Radboud University Medical Center | 36 | 2012-10-01 | 2014-10-28 |
| Δ9-THC (Namisol®) in Chronic Pancreatitis Patients Suffering From Persistent Abdominal Pain Tetrahydrocannabinol, Placebo - Pancreatitis, Chronic, Abdominal Pain | Phase 2 | Completed | Radboud University Medical Center | 29 | 2012-10-01 | 2014-10-28 |
| Ultrasound Guided Transversus Abdominis Plane (TAP) vs. Trigger Point Injection (TPI) for Abdominal Wall Pain Bupivacaine 0.25%, Triamcinolone - Abdominal Pain | Phase 2 | Completed | Mayo Clinic | 62 | 2012-01-01 | 2020-05-14 |
| Acupuncture Treatment for Gastroparesis: a Pilot Study Acupuncture for gastroparesis, Acupuncture for musculoskeletal pain - Gastroparesis, Nausea | Phase 1 / Phase 2 | Completed | Johns Hopkins University | 20 | 2011-11-01 | 2016-09-02 |
| Efficacy Study of Δ9-THC to Treat Chronic Abdominal Pain Namisol, Diazepam - Cannabinoid, Tetrahydrocannabinol | Phase 2 | Completed | Radboud University Medical Center | 24 | 2011-10-01 | 2013-07-09 |
| Internet Intervention for Adolescents With Chronic Pain Online Behavioral Intervention, Education: Online Patient Education - Chronic Pain, Abdominal Pain | Phase 2 | Completed | Seattle Children's Hospital | 273 | 2011-05-01 | 2018-10-03 |
| Efficacy and Safety Study of ACZ885 in Patients With Active Recurrent or Chronic TNF-receptor Associated Periodic Syndrome (TRAPS). ACZ885 - TNF-receptor Associated Periodic Syndromes (TRAPS) | Phase 2 | Completed | Novartis Pharmaceuticals | 20 | 2010-10-01 | 2016-02-04 |
| Mesalamine Granules for Irritable Bowel Syndrome (IBS) With Diarrhea Placebo, Mesalamine Granules 750 mg, Mesalamine Granules 1500 mg - Irritable Bowel Syndrome With Diarrhea | Phase 2 | Completed | Bausch Health Americas, Inc. | 148 | 2010-07-01 | 2019-11-21 |
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Irritable Bowel Syndrome (9) · Diarrhea (5) · Nausea (5) · Chronic Pain (4) · Vomiting (4) · Colonic Diseases (3) · Gastrointestinal Diseases (3) · Headache (3) · Visceral Pain (3) · Anxiety Disorders (2) · Constipation (2) · Digestive System Diseases (2) · Dyspepsia (2) · Fever (2)
Neurologic Manifestations (35) · Pathological Conditions, Signs and Symptoms (35) · Signs and Symptoms (35) · Signs and Symptoms, Digestive (35) · Pain (33) · Digestive System Diseases (15) · Gastrointestinal Diseases (10) · Colonic Diseases, Functional (9) · Intestinal Diseases (9) · Colonic Diseases (7) · Pathologic Processes (5) · Nociceptive Pain (3) · Pancreatic Diseases (3) · Body Temperature Changes (2) · Chronic Disease (2)
Dronabinol (3) · Cognitive Behavioral Therapy (2) · 12,13-dihydro-N-methyl-6,11,13-trioxo-5H-benzo(4,5)cyclohepta(1,2-b)naphthalen-5,12-imine (1) · Acupuncture Therapy (1) · Amitriptyline (1) · Bisacodyl (1) · Bupivacaine (1) · Citalopram (1) · Control Groups (1) · Diazepam (1) · Elimination Diets (1) · Escitalopram (1) · Hesperidin (1) · KHK4083 (1) · Lithotripsy (1)
Mayo Clinic (3) · Radboud University Medical Center (3) · Bausch Health Americas, Inc. (2) · Seattle Children's Hospital (2) · Alexza Pharmaceuticals, Inc. (1) · Arena Pharmaceuticals (1) · Azienda Ospedaliero-Universitaria di Modena (1) · Baylor College of Medicine (1) · Boehringer Ingelheim (1) · CinDome Pharma, Inc. (1) · Erasme University Hospital (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · IWK Health Centre (1) · Ironwood Pharmaceuticals, Inc. (1) · John V. Campo, M.D. (1)
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PMID 27720917, PMID 19695776, PMID 22343090, PMID 22511033, PMID 22773240, PMID 23277304, PMID 25761431, PMID 25775441, PMID 25921377, PMID 26166166, PMID 27080737, PMID 27269295, PMID 27474763, PMID 29199141, PMID 29578090, PMID 30284674, PMID 30525951, PMID 33433147, PMID 33863856, PMID 34854473, PMID 38123024, PMID 39356039
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