5 completed, 1 terminated. 2 Phase 1, 2 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Completed 2 |
| Phase 2 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 1, Terminated 1 |
Follow KHK4083: new trials by email Literature Review of KHK4083 trials Research Report on KHK4083
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study Assessing Rocatinlimab on Vaccine Antibody Response in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET - VOYAGER) Rocatinlimab, Placebo - Atopic Dermatitis, Moderate-to-severe Atopic Dermatitis | Phase 3 | Completed | Amgen | 221 | 2023-06-07 | 2026-07-23 |
| A Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult and Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD) Rocatinlimab, Placebo - Atopic Dermatitis | Phase 3 | Terminated | Amgen | 2621 | 2023-05-31 | 2026-07-16 |
| Study of an Anti-OX40 Monoclonal Antibody (KHK4083) in Subjects With Moderate to Severe Atopic Dermatitis KHK4083, Placebo - Atopic Dermatitis | Phase 2 | Completed | Kyowa Kirin, Inc. | 274 | 2018-10-22 | 2024-04-26 |
| A Phase 1 Study of KHK4083 in Subjects With Atopic Dermatitis KHK4083 - Dermatitis, Atopic | Phase 1 | Completed | Kyowa Kirin Co., Ltd. | 26 | 2017-04-10 | 2018-03-27 |
| A Phase 1 Study of KHK4083 in Healthy Volunteers and Subjects With Ulcerative Colitis KHK4083, Placebo - Healthy Men and Subjects With Ulcerative Colitis | Phase 1 | Completed | Kyowa Kirin Co., Ltd. | 155 | 2016-12-01 | 2023-08-30 |
| Study of a Monoclonal Antibody KHK4083 in Moderate Ulcerative Colitis KHK4083, Placebo - Ulcerative Colitis, Digestive System Diseases | Phase 2 | Completed | Kyowa Kirin, Inc. | 66 | 2016-06-01 | 2024-04-26 |
Dermatitis, Atopic (4) · Eczema (2) · Abdominal Pain (1) · Autoimmune Diseases (1) · Colitis (1) · Colitis, Ulcerative (1) · Colonic Diseases (1) · Digestive System Diseases (1) · Gastrointestinal Diseases (1) · Inflammatory Bowel Diseases (1) · Intestinal Diseases (1) · Skin Diseases (1)
Amgen (2) · Kyowa Kirin Co., Ltd. (2) · Kyowa Kirin, Inc. (2)
Japan (4) · United States (4) · Canada (3) · Czechia (2) · Germany (2) · Hungary (2) · Poland (2) · Romania (2) · Argentina (1) · Australia (1) · Austria (1) · Belgium (1) · Brazil (1) · Bulgaria (1) · Chile (1)
Ehsanollah Esfandiari, MD, PhD (1) · Vincent Strout, MBA (1)