6 completed, 4 terminated, 3 recruiting, 2 active not recruiting. 19 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 19 | Completed 6, Terminated 4, Recruiting 3, Active not recruiting 2, Unknown 2, Enrolling by invitation 1, Withdrawn 1 |
Follow Wrist Fractures: new trials by email Literature Review of Wrist Fractures trials Research Report on Wrist Fractures
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Trial on the Use of Lidocaine Infusion During Surgery for Pediatric Upper Extremity Fractures and Its Impact on Total Perioperative Opioid Requirements Lidocaine Infusion, Standard of Care (SOC) - Fracture Arm, Fracture Closed of Lower End of Forearm, Unspecified | Phase 4 | Recruiting | Nemours Children's Clinic | 90 | 2026-06-24 | 2026-07-06 |
| Wrist Reduction Intervention: Supracondylar Technique for Radial Nerve Block vs. Hematoma Block (WRIST Block Study) Supracondylar radial nerve block, Hematoma block, Combination of blocks - Wrist Fracture | Phase 4 | Enrolling by invitation | Sarasota Memorial Health Care System | 105 | 2025-12-09 | 2026-10-26 |
| Topical TRanexamic Acid vs. Placebo on Acute Postoperative Pain Following DRF Fixation Topical TRanexamic Acid, Placebo - Distal Radius Fractures | Phase 4 | Recruiting | University Health Network, Toronto | 90 | 2025-08-13 | 2026-05-04 |
| Ropivacaine Concentration and Rebound Pain Ropivacaine concentration low, Ropivacaine concentration high - Radius Fracture Distal, Rebound Pain | Phase 4 | Completed | Oslo University Hospital | 80 | 2025-02-14 | 2026-04-20 |
| Brachial Plexus Nerve Block Versus Haematoma Block for Closed Reduction of Distal Radius Fracture in Adults - The BLOCK Trial. A Multicentre Randomised Controlled Trial. Ultrasound-guided brachial plexus block, Haematoma Block - Distal Radius Fractures, Fracture Dislocation | Phase 4 | Active not recruiting | Nordsjaellands Hospital | 1716 | 2024-12-10 | 2026-09-21 |
| Osteogenon in Orthopedics and Traumatology received an ossein-hydroxyapatite complex - Patients With Fractures | Phase 4 | Recruiting | University of Opole | 150 | 2024-11-01 | 2025-11-28 |
| Vitamin c Supplementation in the Prevention of CRPS Following Distal Radius Fractures Vitamin C, Placebo - Distal Radius Fracture, Vitamine c | Phase 4 | Completed | Damascus University | 220 | 2023-06-15 | 2026-03-19 |
| The Efficacy of Liposomal Bupivacaine in Ultrasound Guided Supraclavicular Nerve Blocks for Hand and Wrist Surgery Liposomal bupivacaine (LB), Dexamethasone - Hand Surgery, Wrist Surgery | Phase 4 | Active not recruiting | St. Luke's Hospital, Pennsylvania | 120 | 2023-05-01 | 2025-02-06 |
| Celecoxib in Postoperative Analgesia for Radius Fracture Surgery Celecoxib 100 mg, Placebo - Pain, Postoperative | Phase 4 | Completed | Charles University, Czech Republic | 42 | 2022-02-10 | 2024-02-07 |
| The Role of Tranexamic Acid in Reducing Post Operative Hand Edema After Hand and Wrist Surgery Tranexamic acid, Surgery - Hand Injuries and Disorders, Distal Radius Fracture | Phase 4 | Unknown | Ruby Grewal | 50 | 2021-06-01 | 2021-06-01 |
| Systemic Absorption of Lidocaine After Hematoma Block Lidocaine 1% Injectable Solution - Radius Fracture Distal, Hematoma | Phase 4 | Withdrawn | Washington University School of Medicine | 2020-11-01 | 2023-12-18 | |
| Narcotic Versus Non-narcotic Medication for Pain Management After Wrist/Hand Fractures Hydrocodone 5Mg/Acetaminophen 500Mg Tab, Acetaminophen 500Mg Tab, Ibuprofen 600 mg tab - Distal Radius Fracture, Pain Management | Phase 4 | Unknown | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 250 | 2019-08-01 | 2021-03-01 |
| Perioperative Glucocorticoid Administration in the Treatment of Adult Distal Radius Fractures Dexamethasone, Methylprednisolone - Distal Radius Fracture | Phase 4 | Terminated | C. Liam Dwyer | 38 | 2019-07-10 | 2026-04-30 |
| Effect of NSAID Use on Pain and Opioid Consumption Following Distal Radius Fracture Ibuprofen, Acetaminophen - Distal Radius Fracture | Phase 4 | Terminated | University of Missouri-Columbia | 32 | 2019-01-02 | 2024-09-05 |
| Postsurgical Bupivacaine Extended-release Liposome Injection for Open-reduction Internal Distal Radius Fixation. Exparel, Placebo - Distal Radius Fracture | Phase 4 | Terminated | University of Louisville | 30 | 2015-08-01 | 2017-11-20 |
| Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries Acetaminophen, Ketorolac Tromethamine, Saline - Postoperative Pain, Carpal Tunnel Release | Phase 4 | Completed | John Fowler | 44 | 2015-05-01 | 2018-05-04 |
| 2.4 mm Variable Angle LCP Two-Column Volar Distal Radius Variable Angle Distal Radius Plate ® (Surgery) - Distal Radius Fractures | Phase 4 | Completed | AO Clinical Investigation and Publishing Documentation | 74 | 2010-06-01 | 2014-09-19 |
| Cast Versus Splint in Children With Acceptably Angulated Wrist Fractures Fiberglass short arm cast, Prefabricated wrist splint - Distal Radius Fractures | Phase 4 | Completed | The Hospital for Sick Children | 96 | 2007-01-01 | 2017-10-09 |
| Surgical Plate Osteosynthesis of Distal Radius Fractures Locking Compression Plate 2,4mm, Locking Compression Plate 3,5mm - Distal Radius Fractures | Phase 4 | Terminated | AO Clinical Investigation and Publishing Documentation | 450 | 2001-12-01 | 2007-04-27 |
Dupuytren Contracture (2) · Fractures, Bone (2) · Pain, Postoperative (2) · Acute Pain (1) · Agnosia (1) · Carpal Tunnel Syndrome (1) · Colles' Fracture (1) · Disease (1) · Edema (1) · Elbow Fractures (1) · Fracture Dislocation (1) · Hand Injuries (1) · Hematoma (1) · Radius Fractures (1)
Arm Injuries (19) · Wounds and Injuries (19) · Wrist Injuries (19) · Fractures, Bone (17) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (5) · Neurologic Manifestations (4) · Pathologic Processes (4) · Musculoskeletal Diseases (3) · Pain (3) · Connective Tissue Diseases (2) · Contracture (2) · Fibroma (2) · Muscular Diseases (2) · Neoplasms (2)
Acetaminophen (3) · Dexamethasone (2) · Ibuprofen (2) · Surgical Procedures, Operative (2) · Tranexamic Acid (2) · Ascorbic Acid (1) · Celecoxib (1) · Hydrocodone (1) · Ketorolac Tromethamine (1) · Lidocaine (1) · Methylprednisolone (1) · Oxycodone (1) · Sodium Chloride (1) · Standard of Care (1)
AO Clinical Investigation and Publishing Documentation (2) · C. Liam Dwyer (1) · Charles University, Czech Republic (1) · Damascus University (1) · John Fowler (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · Nemours Children's Clinic (1) · Nordsjaellands Hospital (1) · Oslo University Hospital (1) · Ruby Grewal (1) · Sarasota Memorial Health Care System (1) · St. Luke's Hospital, Pennsylvania (1) · The Hospital for Sick Children (1) · University Health Network, Toronto (1) · University of Louisville (1)
United States (8) · Canada (4) · Germany (2) · Austria (1) · Czechia (1) · Denmark (1) · Norway (1) · Poland (1) · Switzerland (1) · Syria (1) · United Kingdom (1)
Andreas Schierz, MD (1) · Andreas W Wentzensen, Prof. MD (1) · Anette Aasen, MD, Anesthesiologist (1) · Anna Ng-Pellegrino, MD (1) · Anne-Sofie Jellestad, MD, PhD-fellow (1) · Cecilie D Harwood, MD, PhD-fellow (1) · Daniel A London, MD (1) · Danielle Glaze, DO (1) · David Seligson, MD (1) · Jesse B Jupiter, MD (1) · Jesse B Jupiter, Prof. MD (1) · Joy C MacDermid, PhD (1) · Kathy Boutis, MD (1) · Liam Dwyer, MD (1)