41 completed, 12 recruiting, 10 unknown, 5 not yet recruiting. 24 Not applicable, 13 Phase 3, 11 Phase 4, 9 Phase 2, 2 Phase 1.
Follow Dupuytren Contracture: new trials by email Literature Review of Dupuytren Contracture trials Research Report on Dupuytren Contracture
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| DEPART Study at Yale Radiation Therapy - Dupuytren's Contracture | Phase 3 | Not yet recruiting | Yale University | 158 | 2026-11-01 | 2026-10-13 |
| Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal Test Diagnostic Advance Care Planning Discussion, Informational Statement Only - Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS) | Not applicable | Not yet recruiting | University of Texas at Austin | 220 | 2026-10-25 | 2026-09-22 |
| NAC-REPAIR for Post-surgical Pain NAC, NAC 0mg/day (Placebo) - Carpal Tunnel Surgery, Trigger Finger Disorder | Phase 2 | Not yet recruiting | University of Arizona | 80 | 2026-10-15 | 2026-07-17 |
| Effect of Transfer Energy Capacitive and Resistive Therapy on Palmar Fibromatosis Transfer Energy Capacitive and Resistive (TECAR) therapy, Traditional therapy - Palmar Fibromatosis | Not applicable | Not yet recruiting | Cairo University | 36 | 2026-03-02 | 2026-03-02 |
| Prognostic Profile of Dupuytren's Disease: a Cohort Study (PRODUCT) Questionnaires, Clinical examination - Dupuytren's Disease | Not applicable | Not yet recruiting | GCS Ramsay Santé pour l'Enseignement et la Recherche | 305 | 2026-02-04 | 2026-01-20 |
| Ultrasound Features of Dupuytren's Disease Ultrasound assesment, ROM measurement - Dupuytren Disease | Not applicable | Recruiting | Universitaire Ziekenhuizen KU Leuven | 20 | 2025-04-24 | 2026-03-16 |
| Evaluating Ultrasound-Guided Needle Knife for Dupuytren's Contracture Ultrasound guided needle knife dissection - Dupuytren Contracture | Not applicable | Recruiting | Mohamed Maher Ismail Ahmed Elashmawy | 30 | 2025-01-19 | 2025-01-27 |
| Skin Involvement in Dupuytren Surgical Treatment Outcome Suction cutometry, Ultrasound measurement, Microbiopsy for histological analysis - Dupuytren Disease | Not applicable | Active not recruiting | Universitaire Ziekenhuizen KU Leuven | 50 | 2024-12-10 | 2026-07-10 |
| Radiation Therapy for Dupuytren's Contracture Following Non-Surgical Release Radiation therapy - Dupuytren Contracture | Not applicable | Recruiting | Dartmouth-Hitchcock Medical Center | 95 | 2024-09-16 | 2026-07-28 |
| Safety and Efficacy Study of Collagenase CNT201 Injection for Treatment of Dupuytren's Contracture [Step1] CNT201 First-dose, [Step1] CNT201 Low-dose, [Step1] CNT201 Intermediate-dose - Dupuytren Contracture, Dupuytren Disease of Finger | Phase 1 / Phase 2 | Recruiting | CONNEXT | 60 | 2024-07-23 | 2026-06-12 |
| Effect Of Extracorporeal Shock Wave Therapy On Ultrasonography Changes In Patients With Palmar Fibromatosis: A Randomized Controlled Trial Extracorporeal Shock Wave Therapy, traditional treatment - Palmar Fibromatosis | Not applicable | Completed | Cairo University | 60 | 2024-03-04 | 2026-07-14 |
| Palmaris Longus Muscle and Dupuytren Non-invasive tests to determine the presence or absence of the palmaris longus tendon in both hands., Ultrasound - Dupuytren's Disease | Not applicable | Completed | Universitaire Ziekenhuizen KU Leuven | 243 | 2024-02-16 | 2026-03-09 |
| Nodular Shrinking in Dupuytren Disease Vitamin E-creme (Remederm®) vs Vaseline (Placebo), Ultrasound measurement - Dupuytren's Disease | Phase 2 | Recruiting | Universitaire Ziekenhuizen KU Leuven | 80 | 2024-02-15 | 2026-05-11 |
| Goniometry and Goniometric Measurement on Standardised Images in Dupuytren's Disease ROM measurement of the MCP and PIP joints in digits 4 and 5 - Dupuytren's Disease | Completed | Universitaire Ziekenhuizen KU Leuven | 59 | 2024-01-29 | 2025-07-29 | |
| Micronerves in Dupuytren and the Impact of Its Dissection on Recurrence Microfasciectomy - Dupuytren's Disease | Recruiting | Universitaire Ziekenhuizen KU Leuven | 80 | 2024-01-01 | 2026-03-16 | |
| Real-World Data Study to Understand Participant Treatment Outcomes for Dupuytren's Contracture Dupuytren's Contracture | Terminated | Endo USA Inc., a Keenova Therapeutics Company | 130 | 2023-06-14 | 2024-04-16 | |
| The Efficacy of Liposomal Bupivacaine in Ultrasound Guided Supraclavicular Nerve Blocks for Hand and Wrist Surgery Liposomal bupivacaine (LB), Dexamethasone - Hand Surgery, Wrist Surgery | Phase 4 | Active not recruiting | St. Luke's Hospital, Pennsylvania | 120 | 2023-05-01 | 2025-02-06 |
| Percutaneous Needle Fasciotomy +/- Corticosteroid Injection for Dupuytren's Contracture Percutaneous needle fasciotomy, Corticosteroid injection, Saline injection - Dupuytren Contracture, Dupuytren's Disease | Phase 4 | Recruiting | Regionshospitalet Silkeborg | 400 | 2023-01-10 | 2023-05-17 |
| Efficacy of Aponeurectomy on the 2-year Recurrence Rate of Dupuytren's Disease Aponeurectomy with grafting, Aponeurectomy alone - Dupuytren's Disease | Not applicable | Recruiting | Elsan | 172 | 2022-09-29 | 2026-04-23 |
| Effectiveness of Night Splinting After Percutaneous Needle Fasciotomy in Dupuytren's Contracture No night splint - Dupuytren Contracture, Dupuytren's Disease | Not applicable | Recruiting | Uppsala University | 154 | 2022-09-14 | 2024-05-31 |
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Contracture (6) · Trigger Finger Disorder (6) · Carpal Tunnel Syndrome (5) · Connective Tissue Diseases (5) · Wrist Fractures (4) · Arthritis (3) · Ganglion Cysts (3) · Musculoskeletal Diseases (3) · De Quervain Disease (2) · Edema (2) · Joint Diseases (2) · Osteoarthritis (2) · Rare Diseases (2) · Cicatrix (1)
Skin and Connective Tissue Diseases (75) · Fibroma (74) · Muscular Diseases (74) · Neoplasms (74) · Neoplasms by Histologic Type (74) · Neoplasms, Connective Tissue (74) · Neoplasms, Connective and Soft Tissue (74) · Neoplasms, Fibrous Tissue (74) · Musculoskeletal Diseases (72) · Connective Tissue Diseases (70) · Contracture (69) · Joint Diseases (9) · Pathological Conditions, Signs and Symptoms (9) · Wounds and Injuries (9) · Nervous System Diseases (7)
Microbial Collagenase (16) · xiapex (12) · Collagenases (4) · Surgical Procedures, Operative (3) · Radiotherapy (2) · Sodium Chloride (2) · Acetaminophen (1) · Adalimumab (1) · Adrenal Cortex Hormones (1) · Arthroplasty, Replacement, Elbow (1) · Arthroplasty, Replacement, Knee (1) · Arthroplasty, Replacement, Shoulder (1) · Dexamethasone (1) · Enzymes (1) · Extracorporeal Shockwave Therapy (1)
Endo USA Inc., a Keenova Therapeutics Company (10) · Universitaire Ziekenhuizen KU Leuven (6) · Cairo University (2) · GCS Ramsay Santé pour l'Enseignement et la Recherche (2) · Indiana Hand to Shoulder Center (2) · State University of New York (2) · Sunnybrook Health Sciences Centre (2) · University Medical Center Groningen (2) · University of Oxford (2) · University of Texas at Austin (2) · Asahi Kasei Therapeutics Corporation (1) · Assistance Publique - Hôpitaux de Paris (1) · Azienda Ospedaliera Universitaria Integrata Verona (1) · CONNEXT (1) · Centre Hospitalier Universitaire de Nice (1)
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Ilse Degreef, Prof. Dr. (5) · Veronica Urdaneta, MD (3) · Veronica Urdaneta, MD, MPPH (3) · Lawrence C Hurst, MD (2) · Lawrence C. Hurst (2) · Achilleas Thoma, MD MSC (1) · Achilleas Thoma, MD MSc FRCSC (1) · Aleksi RP Reito, M.D., Ph.D., adjunct professor (1) · Alidad Ghiassi, MD (1) · Amir Zaki, PHD (1) · Anna Ng-Pellegrino, MD (1) · Antti OV Malmivaara, M.D., Ph.D., adjunct professor (1) · Bruce McGibbon, MD (1) · Charlotte Hartig-Andreasen, MD, PhD (1) · Daniel Herren, Dr. med. (1)
PMID 19726771, PMID 21967070, PMID 23190833, PMID 24470559, PMID 24569424, PMID 27313184, PMID 28854973, PMID 29983350, PMID 30722822, PMID 30786996, PMID 31455312, PMID 33381769, PMID 33410485, PMID 33483776, PMID 34233971, PMID 34397515, PMID 35938625, PMID 35949922, PMID 36378072, PMID 36758713, PMID 38346307, PMID 39223657, PMID 39749555, PMID 41334972
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