12 completed, 3 unknown, 1 withdrawn. 16 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 16 | Completed 12, Unknown 3, Withdrawn 1 |
Follow Vitamin B Deficiency: new trials by email Literature Review of Vitamin B Deficiency trials Research Report on Vitamin B Deficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to See if a Combination of Vitamins That is Injected Into a Muscle is as Good and Safe as a Vitamin That is Taken by Mouth Vitamin B12, Vitamin B6, Folic acid, Vitamin B12 (Cyanocobalamin) - Vitamin B12 Deficiency | Phase 4 | Completed | Medice Arzneimittel Pütter GmbH & Co KG | 46 | 2025-04-16 | 2026-09-04 |
| The Thiamine Administration After Cardiac Surgery Trial Thiamine 500 MG, Placebo - Lactate Blood Increase, Thiamine Deficiency | Phase 4 | Completed | Sarah Saxena | 200 | 2020-11-20 | 2022-11-17 |
| A Study of Serum Folate Levels in Patients Treated With Olaparib Folic Acid Tablet - Ovarian Cancer, Breast Cancer | Phase 4 | Completed | Rush University Medical Center | 10 | 2020-07-21 | 2026-03-04 |
| The Effect of SLC19A3 Inhibition on the Pharmacokinetics of Thiamine Trimethoprim, Metformin, Vitamin B1 - Vitamin B1 Deficiency, Thiamine Deficiency | Phase 4 | Completed | University of California, San Francisco | 7 | 2019-01-28 | 2025-01-03 |
| Thiamine Influenced on Substrate Energy Effectiveness in Indonesian Children Undergoing Cardiopulmonary Bypass Neurobion, Placebo - Thiamine Deficiency, Congenital Heart Disease | Phase 4 | Unknown | National Cardiovascular Center Harapan Kita Hospital Indonesia | 50 | 2018-07-01 | 2020-07-01 |
| Megadose of Hydroxocobalamin for the Treatment of Pernicious Anemia Hydroxocobalamin 10,000mcg, Thiamin 100mg, Pyridoxine 50mg - Megaloblastic Anemia Nos, Pernicious Anemia | Phase 4 | Completed | Hospital Universitario Dr. Jose E. Gonzalez | 13 | 2017-12-27 | 2021-03-08 |
| Feasibility Study of the Intensive Systolic Blood Pressure Control Standard BP control, Moderate BP control, Intensive BP control - Hypertension, Hyperhomocysteinemia | Phase 4 | Unknown | Second Affiliated Hospital of Nanchang University | 100 | 2015-12-01 | 2016-10-14 |
| Thiamin Deficiency in Obese Thai Children Thiamine 1, Non-thiamine, Thiamine 2 - Obesity, Child | Phase 4 | Completed | Mahidol University | 124 | 2015-08-01 | 2018-10-02 |
| Vitamin Deficiencies and Suppletion in Morbid Obesity Hydroxocobalamin, FitForMe vitamin B12 - Vitamin B12 Deficiency | Phase 4 | Completed | Rijnstate Hospital | 50 | 2014-10-01 | 2020-06-11 |
| Vitamin B12 Acceptance and Biomarker Response Study Oral administration of vitamin B12, i.m. injection of vitamin B12 - Vitamin B 12 Deficiency | Phase 4 | Completed | University Hospital, Basel, Switzerland | 37 | 2013-05-01 | 2016-06-14 |
| Effect of Folic Acid Supplementation on Plasma Homocysteine Level in Obese Children Folic Acid, placebo - Hyperhomocysteinemia, Obesity | Phase 4 | Completed | Queen Sirikit National Institute of Child Health | 50 | 2012-12-01 | 2015-12-11 |
| Preoperative Parenteral Thiamine Supplementation in Patients Undergoing Heart Surgery Vitamin B1-ratiopharm, Placebo - Heart Failure, Acidosis, Lactic | Phase 4 | Completed | Medical University of Vienna | 30 | 2012-02-01 | 2021-02-26 |
| A Trial of Thiamin Supplementation in Patients With Heart Failure Vitamin B1, Placebo - Heart Failure | Phase 4 | Completed | Unity Health Toronto | 70 | 2009-09-01 | 2018-02-27 |
| CSPPT- Chronic Kidney Diseases Study Enalapril maleate and folic acid tablets, Enalapril maleate - Hypertension, Hyperhomocysteinemia | Phase 4 | Withdrawn | Shenzhen Ausa Pharmed Co.,Ltd | 2008-05-01 | 2016-01-20 | |
| How Many Patients Are in Need of Vitamin B12 Injections? vitamin B12 - Vitamin B12 Deficiency | Phase 4 | Unknown | University of Aarhus | 50 | 2006-01-01 | 2008-08-08 |
| Uremic Hyperhomocysteinemia -A Folate Trial for Possible Prevention of Cardiovascular Events folate treatment - Uremia, Chronic Renal Failure | Phase 4 | Completed | Universidade Estadual de Londrina | 186 | 2003-04-01 | 2018-07-26 |
Thiamine Deficiency (5) · Hyperhomocysteinemia (4) · Vitamin B 12 Deficiency (4) · Beriberi (2) · Heart Failure (2) · Hypertension (2) · Obesity (2) · Acidosis, Lactic (1) · Anemia, Megaloblastic (1) · Anemia, Pernicious (1) · Breast Neoplasms (1) · Cardiovascular Diseases (1) · Folic Acid Deficiency (1) · Heart Defects, Congenital (1) · Hyperlactatemia (1)
Avitaminosis (16) · Deficiency Diseases (16) · Malnutrition (16) · Nutrition Disorders (16) · Nutritional and Metabolic Diseases (16) · Metabolic Diseases (6) · Cardiovascular Diseases (5) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (5) · Pathological Conditions, Signs and Symptoms (5) · Amino Acid Metabolism, Inborn Errors (4) · Genetic Diseases, Inborn (4) · Malabsorption Syndromes (4) · Metabolism, Inborn Errors (4) · Female Urogenital Diseases (3)
Thiamine (5) · Folic Acid (4) · Hydroxocobalamin (2) · Vitamin B 12 (2) · Enalapril (1) · Hydrochlorothiazide (1) · Metformin (1) · Pyridoxine (1) · Sodium Chloride (1) · Thymidine Monophosphate (1) · Trimethoprim (1) · Vitamin B 6 (1) · Vitamin B Complex (1)
Hospital Universitario Dr. Jose E. Gonzalez (1) · Mahidol University (1) · Medical University of Vienna (1) · Medice Arzneimittel Pütter GmbH & Co KG (1) · National Cardiovascular Center Harapan Kita Hospital Indonesia (1) · Queen Sirikit National Institute of Child Health (1) · Rijnstate Hospital (1) · Rush University Medical Center (1) · Sarah Saxena (1) · Second Affiliated Hospital of Nanchang University (1) · Shenzhen Ausa Pharmed Co.,Ltd (1) · Unity Health Toronto (1) · Universidade Estadual de Londrina (1) · University Hospital, Basel, Switzerland (1) · University of Aarhus (1)
China (2) · Thailand (2) · United States (2) · Austria (1) · Belgium (1) · Brazil (1) · Canada (1) · Denmark (1) · Indonesia (1) · Mexico (1) · Netherlands (1) · Switzerland (1) · Ukraine (1)
Altair J Mocelin, MD PHD (1) · Andrew S Greenberg (1) · Anne-Mette Hvas, MD, PhD (1) · Cyrill Jeger, MD (1) · Eva M Marwali, MD, PhD (1) · Fanfan Hou, MD (1) · Kathleen M Giacomini (1) · Kurt E Hersberger, Professor (1) · Lydia Usha, MD (1) · MIchael Piagnerelli, MD; PHD (1) · Mary E. Keith, PhD, RD (1) · Michael Hiesmayr, Prof.,MD (1) · Narumon Densupsoontorn, MD (1) · Orawan Iamopas, MD. (1)
PMID 26066773, PMID 14616423, PMID 15286537, PMID 17429582, PMID 17583412, PMID 19325467, PMID 20179283, PMID 20181242, PMID 20463176, PMID 20646908, PMID 21623649, PMID 22650964, PMID 23649098, PMID 23697526, PMID 23842591, PMID 23945419, PMID 24412011, PMID 25391194, PMID 25479113, PMID 26771781, PMID 27002274, PMID 28185643, PMID 28360040, PMID 28421567, PMID 28432843, PMID 29047411, PMID 29931179, PMID 30813144, PMID 31504093, PMID 32527283
R01DK108722 (1)