47 completed, 11 unknown, 9 terminated, 8 recruiting. 31 Not applicable, 19 Phase 2, 19 Phase 3, 12 Phase 4, 8 Phase 1.
Follow Vitamin B 6: new trials by email Literature Review of Vitamin B 6 trials Research Report on Vitamin B 6
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vitamin B6 on Exercise Pressor Reflex on Leg Ischemia-reperfusion Vitamin B6 25 MG, Vitamin B6 50 MG, Vitamin B6 100 MG - Ischemia Reperfusion Injury, Peripheral Artery Disease | Early Phase 1 | Not yet recruiting | Milton S. Hershey Medical Center | 30 | 2027-12-01 | 2026-03-17 |
| B6 Administration for Levetiracetam-Associated Neurobehavioral Changes and Epilepsy Vitamin B6 100 MG - Brain Tumor Related Epilepsy (BTRE) | Not applicable | Recruiting | Duke University | 50 | 2026-05-29 | 2026-07-29 |
| Omega-3-Based Nutraceutical Supplementation as Adjunctive Therapy in Adults With Otitis Media With Effusion: A Multicenter, Double-Blind, Randomized Placebo-Controlled Trial Omega-3-based nutraceutical combination (Otoair Flogo), Bilastine 20 mg, Placebo Tablet or Capsule - Otits Media With Effusion | Phase 4 | Completed | Isola Tiberina - Gemelli Isola Hospital, Rome, Italy | 501 | 2025-10-01 | 2026-07-23 |
| Comparative Study of Combination Treatment of Bionerv E+ Versus Vitamin B Complex in Treatment of Diabetic Polyneuropathy in Type 2 Diabetic Patients and Its Effect on Wound Healing Alpha-Lipoic Acid, Vitamin B1, Vitamin B6, Vitamin B12, Vitamin E, Vitamin B1, Vitamin B6, Vitamin B12 - Diabetic Foot Ulcer (DFU), Diabetic Symmetrical Polyneuropathy | Not applicable | Recruiting | BREGO Life Sciences | 100 | 2025-07-22 | 2026-10-16 |
| Date Fruit Benefits to Treat Morning Sickness in First Trimester of Pregnancy Date fruit, Doxylamine succinate 10 mg + Pyridoxine HCl 10 mg, Diet - Pregnancy | Not applicable | Active not recruiting | Bahria University | 40 | 2025-06-15 | 2026-01-21 |
| A Study to See if a Combination of Vitamins That is Injected Into a Muscle is as Good and Safe as a Vitamin That is Taken by Mouth Vitamin B12, Vitamin B6, Folic acid, Vitamin B12 (Cyanocobalamin) - Vitamin B12 Deficiency | Phase 4 | Completed | Medice Arzneimittel Pütter GmbH & Co KG | 46 | 2025-04-16 | 2026-09-04 |
| Treatment With Apixaban Versus Warfarin in Patients With Left Ventricular Thrombus After Acute Myocardial Infarction Apixaban, Warfarin - Left Ventricular Thrombus, Acute Myocardial Infarction | Phase 4 | Recruiting | Karolinska Institutet | 212 | 2025-04-08 | 2025-07-01 |
| Testing the Efficacy of 100mg Vitamin-B6 Daily for Sensory Reactivity in Autism Pyridoxal 5'-Phosphate (100 mg), Placebo - Autism | Not applicable | Recruiting | University of Reading | 40 | 2024-11-08 | 2026-10-07 |
| Effect of Kinesiotape on Emesis in Pregnant Women Antiemetic Drug, Vitamin B6, Home care advice - Emesis Pregnancy | Not applicable | Not yet recruiting | Cairo University | 50 | 2024-10-07 | 2024-10-08 |
| Vitamin B6 and Depression in Pregnant and Peri-partum Women Vitamin B6, Placebo - Postpartum Depression, Heart Rate Variability | Not applicable | Recruiting | National Taiwan University Hospital | 150 | 2024-07-05 | 2026-07-07 |
| Vitamin B6 Aids in Treating Inflammatory Bowel Disease Vitamin B6 Tablets, Placebo - Inflammatory Bowel Diseases | Not applicable | Unknown | Changhai Hospital | 220 | 2024-06-01 | 2024-07-22 |
| The Effects of Vitamin B6 Supplementation on Pain Thresholds and Tolerance Vitamin B6 100 MG, Placebo - Pain | Phase 1 | Completed | University of Reading | 43 | 2024-05-30 | 2026-03-11 |
| A Study of Enlicitide Decanoate (MK-0616), Warfarin, and Lisinopril in Healthy Adult Participants (MK-0616-026) Warfarin, Enlicitide Decanoate, Lisinopril - Healthy | Phase 1 | Completed | Merck Sharp & Dohme LLC | 36 | 2024-04-01 | 2025-01-15 |
| Pilot Study of Open Label Homocysteine Management Therapy in Levodopa-treated Parkinson's Disease Folic Acid 1 MG, Vitamin B6 25 MG, Vitamin B12 - Parkinson&Amp;#39;s Disease | Not applicable | Recruiting | Oregon Health and Science University | 150 | 2024-03-05 | 2025-01-13 |
| The Efficacy of B6 and Metoclopramide Combination in Comparison With the Other Antiemetics Metoclopramide and Vitamin B6, Vitamin B6, Ondansetron - Vomiting | Phase 2 / Phase 3 | Completed | University of Baghdad | 250 | 2024-01-30 | 2024-04-30 |
| Effects of Supplementation of Compound Nutrients on Plasma Homocysteine in Chinese Adults supplementation of compound nutrients, placebo control - Homocysteine | Not applicable | Unknown | Sun Yat-sen University | 220 | 2023-06-01 | 2024-04-12 |
| Pyridoxine Effect on the Blood Glucose Level in Type 2 Diabetic Patients Metformin 500 mg/day, Metformin 500 mg/day plus vitamin B6 300 mg/day, non-pharmacological therapy - Diabetes Mellitus, Type 2 | Not applicable | Completed | Al-Rasheed University College | 108 | 2022-11-01 | 2023-06-26 |
| Effects of Vitamin D, Epigallocatechin Gallate, Vitamin B6, and D-Chiro-inositol Combination on Uterine Fibroids Combination of Epigallocatechin gallate, vitamin D, vitamin B6, and D-Chiro-inositol, Placebo - Leiomyoma, Uterine | Not applicable | Completed | Universita di Verona | 108 | 2022-09-15 | 2026-05-05 |
| High Molecular Weight Hyaluronic Acid, α-lipoic Acid, Magnesium, Vitamin B6 and Vitamin D, in the Prevention of Spontaneous Abortion high molecular weight hyaluronic acid, α-lipoic acid (ALA), magnesium, vitamin B6 and vitamin D - Abortion, Spontaneous | Not applicable | Completed | Lo.Li.Pharma s.r.l | 100 | 2022-09-01 | 2024-02-22 |
| Vitamin D, Epigallocatechin Gallate, D-chiro-inositol and Vitamin B6 in Uterine Fibroid Epigallocatechin gallate, Vitamin D, Vitamin B6, D-chiro-inositol, Placebo - Uterine Fibroids, D-chiro-inositol | Not applicable | Recruiting | Lo.Li.Pharma s.r.l | 60 | 2022-07-01 | 2026-02-12 |
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Tuberculosis (8) · Atrial Fibrillation (4) · Stroke (4) · HIV Infections (3) · Kidney Failure, Chronic (3) · Latent Tuberculosis (3) · Leiomyoma (3) · Vomiting (3) · Acquired Immunodeficiency Syndrome (2) · Attention Deficit Disorder with Hyperactivity (2) · Autism Spectrum Disorder (2) · Autistic Disorder (2) · Cardiovascular Diseases (2) · Diabetes Mellitus, Type 2 (2) · Hemorrhage (2)
National Institute of Allergy and Infectious Diseases (NIAID) (5) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (4) · Taichung Veterans General Hospital (3) · Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (2) · Centers for Disease Control and Prevention (2) · Lo.Li.Pharma s.r.l (2) · National Institute on Aging (NIA) (2) · University of California, San Francisco (2) · University of Padova (2) · University of Reading (2) · AHS Cancer Control Alberta (1) · Al-Rasheed University College (1) · Arizona State University (1) · AstraZeneca (1) · BREGO Life Sciences (1)
United States (26) · Italy (7) · Canada (6) · Haiti (6) · South Africa (6) · Thailand (6) · Bangladesh (4) · Brazil (4) · China (4) · Kenya (4) · Taiwan (4) · Uganda (4) · Zimbabwe (4) · Botswana (3) · Malawi (3)
Richard E. Chaisson, MD (2) · Susan Swindells, MBBS (2) · Umesh Jain, MD (2) · Alice P Chen, M.D. (1) · Amita Gupta, MD, MHS (1) · Anchalee Avihingsanon, MD, PhD (1) · Andrea Baccarelli, MD PHD MPH (1) · Andreas H Diacon, MD, PhD (1) · Anne-Lise Kamper, MD DMSc (1) · Anneke Hesseling, MD, PhD (1) · Anthony Podany, PharmD (1) · Aslak Rautio (1) · Azza Barmoud Nashed Kassab, PhD (1) · Brody Holohan, PhD (1)
PMID 31005968, PMID 12324494, PMID 12507972, PMID 14699020, PMID 15321804, PMID 15910853, PMID 16531613, PMID 16531614, PMID 16543037, PMID 16613998, PMID 17470822, PMID 17645592, PMID 17954810, PMID 18003666, PMID 18419884, PMID 18510727, PMID 18620104, PMID 18714059, PMID 18854539, PMID 18940900, PMID 19118243, PMID 19125808, PMID 19228852, PMID 19414836, PMID 19549699, PMID 19656705, PMID 20484456, PMID 20494665, PMID 21310866, PMID 21514988, PMID 22150035, PMID 23734218, PMID 23936148, PMID 24103380, PMID 24385516, PMID 24647388, PMID 24885137, PMID 25527663, PMID 25770690, PMID 25904367, PMID 26082504, PMID 26123683, PMID 26201817, PMID 26260821, PMID 26722126, PMID 26765812, PMID 26920731, PMID 27010173, PMID 27051670, PMID 27243774
2018 (1), R01AG017160 (1), U01AI068636 (1), UM1AI068636 (1)