Thiopental: Clinical Trials

23 trials of Thiopental, newest first

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19 completed, 3 terminated, 1 unknown. 8 Not applicable, 5 Phase 4, 4 Phase 3, 3 Phase 2, 2 Phase 1.

By phase and status

PhaseTrialsStatus
Not applicable8Completed 8
Phase 45Completed 4, Terminated 1
Phase 34Completed 2, Terminated 2
Phase 23Completed 2, Unknown 1
Phase 12Completed 1, Unknown 1

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Induction Agents in ECT: Effects on Seizure Duration, Quality, and Recovery
Propofol group, Thiopental, Ketamine (0.5 mg/kg) - Electroconvulsive Therapy, Anesthesia, General
Not applicableCompletedDr. Lutfi Kirdar Kartal Training and Research Hospital1002024-07-172026-05-19
The Effects of Propofol and Thiopental on Nitric Oxide Production and Release in Erythrocytes
Propofol, Thiopental - Effect of Drug
Not applicableCompletedMelike Cengiz122024-03-012024-08-01
Dual Anti-glutamate Therapy in Super-refractory Status Epilepticus After Cardiac Arrest
Ketamine, Any anti-epileptic and anesthetic therapy, excluding Ketamine and Perampanel - Status Epilepticus, Cardiac Arrest
CompletedUniversity of Milano Bicocca842022-01-152026-07-14
Ketamine Versus Low Dose Thiopental for Induction of Anesthesia in Septic Shock
Ketamine, Thiopental - Septic Shock
Phase 3CompletedCairo University262017-04-122018-07-10
Understanding How Anaesthesia Affects ECT Outcomes
Electroconvulsive Therapy (ECT) time interval + Anaesthetic (Thiopentone) - Depression
Phase 3CompletedThe University of New South Wales542017-03-152023-03-30
The Effects of Anesthetic Techniques and Palonosetron Administration on the Incidence of PONV
Palonosetron, sevoflurane, remifentanil - PONV, Palonosetron
Phase 4CompletedAjou University School of Medicine1502016-06-012017-07-21
Effects Of Anaesthesia on Intraocular Pressure in Robotic Prostate Surgery
Sevoflurane (Volatile Anesthetic), Propofol 1%, Remifentanil 2 MG - Anaesthesia, Intraocular Pressure
Not applicableCompletedAtaturk Training and Research Hospital602015-07-232025-06-24
Effects of Sedation on Spinal Anesthesia-induced Maternal Hypotension
Sedation, No sedation - Cesarean Section, Preoperative Anxiety
CompletedVan Training and Research Hospital1022014-08-012016-04-11
TELSTAR: Treatment of ELectroencephalographic STatus Epilepticus After Cardiopulmonary Resuscitation
Anti-epileptic drugs, No anti-epileptic drugs - Cardiac Arrest, Anoxic Encephalopathy
Not applicableCompletedUniversity of Twente1722014-04-012022-02-21
The Effects of Remifentanil and Remifentanil-Alfentanil Administration in Children
Sevoflurane, Remifentanil, Alfentanil - Adverse Effect of Other General Anesthetics
Not applicableCompletedHallym University Medical Center1022012-11-012015-07-07
The Cortisol Levels During Cardiac Surgery. The Comparison Between Etomidate and Thiopentone
etomidate, thiopentone - Coronary Artery Disease, Valvular Heart Disease
Phase 4CompletedMahidol University922011-12-012014-05-23
Thiopental Versus Propofol During Magnetic Resonance Imagining in Children: Something Old, Something New
Propofol and Thiopental - Complications
Phase 1 / Phase 2UnknownUniversity Clinical Centre of Kosova1002011-01-012011-03-18
Onset Time of Thiopental Versus Propofol in the Elderly
Thiopental, Propofol - Induction of Anaesthesia, Age
Phase 4CompletedCopenhagen University Hospital, Rigshospitalet782009-09-012010-03-09
The Influence of Induction Anesthetic Agents on Serum Cortisol Concentration in Morbidly Obese Patients.
Intravenous administration of the induction agent of general anesthesia (etomidate or thiopental) - Obesity
Not applicableCompletedMilitary Institute od Medicine National Research Institute822009-06-012013-08-28
Comparative Effect of Theipoental and Propofol in IVF Outcome
Propofol, Thiopental - Subfertility
Phase 4CompletedAristotle University Of Thessaloniki1802009-01-012015-03-04
The Effect of Intravenous Anesthetics on Fear Learning and Memory
Placebos, Propofol 0.45mcg/mL, Propofol 0.90mcg/mL - Phobias
Not applicableCompletedWeill Medical College of Cornell University672008-10-012019-05-15
Neuroimaging the Effects of Intravenous Anesthetic on Amygdala Dependent Memory Processes
Placebo, Propofol, Thiopental - Healthy
Phase 4TerminatedWeill Medical College of Cornell University602007-03-012021-07-15
Treatment of Refractory Status Epilepticus
propofol, thiopental/pentobarbital - Status Epilepticus
Phase 3TerminatedBrigham and Women's Hospital232006-05-012013-04-09
GABA Mechanisms Underlying the Vulnerability to Alcohol Dependence
Thiopental, Placebo - Alcoholism
Not applicableCompletedYale University732005-11-012017-03-17
Effect of Affective Content on Drug Induced Amnesia of Episodic Memory
Propofol, Thiopental Sodium, Dexmedetomidine Hydrochloride - Memory Losses, Amnesia-Memory Loss
Phase 1CompletedMemorial Sloan Kettering Cancer Center792004-09-012015-12-24

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Conditions studied

Status Epilepticus (3)  ·  Heart Arrest (2)  ·  Alcoholism (1)  ·  Amnesia (1)  ·  Brain Injuries, Traumatic (1)  ·  Coronary Artery Disease (1)  ·  Depression (1)  ·  Heart Valve Diseases (1)  ·  Hypoxia, Brain (1)  ·  Infertility (1)  ·  Memory Disorders (1)  ·  Obesity (1)  ·  Phobic Disorders (1)  ·  Postoperative Nausea and Vomiting (1)  ·  Shock, Septic (1)

Sponsors

Weill Medical College of Cornell University (2)  ·  Ajou University School of Medicine (1)  ·  Aristotle University Of Thessaloniki (1)  ·  Ataturk Training and Research Hospital (1)  ·  Brigham and Women's Hospital (1)  ·  Cairo University (1)  ·  Copenhagen University Hospital, Rigshospitalet (1)  ·  Dr. Lutfi Kirdar Kartal Training and Research Hospital (1)  ·  Hallym University Medical Center (1)  ·  Hospital Universitari Son Dureta (1)  ·  Isfahan University of Medical Sciences (1)  ·  Mahidol University (1)  ·  Melike Cengiz (1)  ·  Memorial Sloan Kettering Cancer Center (1)  ·  Military Institute od Medicine National Research Institute (1)

Countries

United States (5)  ·  Turkey (Türkiye) (3)  ·  Iran (2)  ·  Albania (1)  ·  Australia (1)  ·  Belgium (1)  ·  Denmark (1)  ·  Egypt (1)  ·  Greece (1)  ·  Italy (1)  ·  Netherlands (1)  ·  Poland (1)  ·  South Korea (1)  ·  Spain (1)  ·  Switzerland (1)

Top investigators

Ahmed Mukhtar, Professor (1)  ·  Ahmet Yildirim (1)  ·  Andrea O. Rossetti, MD (1)  ·  Antigona Hasani, MD,MSC (1)  ·  Ayse Gulbin Arici, Professor (1)  ·  Barry Ruijter, MD (1)  ·  Cenk Sahan, MD (1)  ·  Colleen Loo, MBBS (1)  ·  Dae Hee Kim, MD (1)  ·  Hilda Mahmoudi, M.D (1)  ·  Ismene L Petrakis, MD (1)  ·  Janneke Horn, MD PhD (1)  ·  Jeannette Hofmeijer, MD PhD (1)  ·  Jon Perez, MD (1)

Results publications

PMID 15756405, PMID 18759980, PMID 20878265, PMID 22964265, PMID 24273687, PMID 26174294, PMID 26384469, PMID 26437535, PMID 26515147, PMID 26971488, PMID 27484339, PMID 35196426, PMID 38991197, PMID 42837646

NIH funding

K08GM083213 (2)