75 completed, 42 unknown, 7 terminated, 6 recruiting. 35 Not applicable, 25 Phase 4, 20 Phase 3, 12 Phase 2.
Follow Unstable Angina: new trials by email Literature Review of Unstable Angina trials Research Report on Unstable Angina
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Early Single Antiplatelet Therapy After IVUS-Guided PCI in Acute Coronary Syndrome Early P2Y12 Inhibitor Monotherapy, Standard Dual Antiplatelet Therapy - Acute Coronary Syndromes, STEMI | Phase 4 | Not yet recruiting | Gyeongsang National University Hospital | 1900 | 2026-07-01 | 2026-07-06 |
| Prospective Lifespan Cohort of Myocardial Infarction Acute Myocardial Infarction (AMI), Stable Angina | Not yet recruiting | Fujian Provincial Hospital | 6000 | 2026-04-10 | 2026-03-25 | |
| Advanced NanoTherapies Dual-API DCB to Treat De-Novo and ISR Lesions in Patients With Symptomatic Coronary Artery Disease SirPlux Duo™ Dual API-Coated PTCA Balloon Catheter - Angina (Stable), CAD - Coronary Artery Disease | Not applicable | Recruiting | Advanced NanoTherapies | 30 | 2025-12-15 | 2026-01-27 |
| Validation of the MedHub AutocathFFR Software Device for Non-Invasive Fractional Flow Reserve (FFR) MedHub AutocathFFR - Coronary Artery Disease, Stable Angina | Completed | Medhub Ltd. | 277 | 2025-11-04 | 2026-08-13 | |
| Clinical Echocardiography and S' Wave for Early Recognition of Acute Coronary Syndrome in the Emergency Department, A Prospective Study Tissue Doppler Imaging (TDI) S' Wave Echocardiography - Acute Coronary Syndrome, Myocardial Infarction (MI) | Not applicable | Completed | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 66 | 2025-01-12 | 2026-04-27 |
| LEADERS FREE IV (RCT): BioFreedom™ Ultra vs BioFreedom™ in HBR Patients BioFreedom™ Ultra cobalt-chromium Biolimus A9™-coated stent, BioFreedom™ stainless steel Biolimus A9™-coated stent - Coronary Artery Disease, Chronic Stable Angina | Not applicable | Recruiting | Biosensors Europe SA | 444 | 2024-12-18 | 2025-06-05 |
| Treatment of ACuTe Coronary Syndromes With Low-dose colchICine Colchicine Pill, Placebo - Acute Coronary Syndrome, Unstable Angina | Not applicable | Recruiting | Beijing Anzhen Hospital | 6574 | 2024-09-02 | 2024-10-30 |
| Telehealth Group Counseling and Preventive Care for Women Telehealth Group Counseling - ASCVD, NSTEMI | Not applicable | Completed | Weill Medical College of Cornell University | 13 | 2024-07-10 | 2025-06-24 |
| European Survey of Cardiovascular Disease Prevention, Diabetes and Chronic Kidney Disease (EUROASPIRE VI) Coronary Disease, Acute Coronary Syndrome | Active not recruiting | European Society of Cardiology | 8000 | 2024-06-07 | 2026-08-20 | |
| Japanese Coronary Intervention Using Drug Eluting and Perfusion Therapy for Left Main Disease (JDEPTH-LM Registry) Stable Angina, Non-ST-elevation Acute Coronary Syndrome | Recruiting | TCROSS Co., Ltd. | 280 | 2024-05-27 | 2025-03-13 | |
| Prasugrel Or Ticagrelor De-escalation in NSTE-ACS De-escalation to ticagrelor 60 mg at day 30, De-escalation to prasugrel 5 mg at day 30, Switch to ticagrelor 60 mg at day 45 - Non ST Segment Elevation Acute Coronary Syndrome, Non-ST-Segment Elevation Myocardial Infarction (NSTEMI) | Phase 3 | Unknown | Collegium Medicum w Bydgoszczy | 50 | 2023-04-01 | 2023-03-22 |
| Incidence, Clinical Characteristics and Outcomes of Unstable Angina in the contempoRary Area. patients who underwent coronary angiography - Unstable Angina | Completed | University Hospital, Montpellier | 210 | 2022-11-27 | 2024-05-02 | |
| Evaluation of the LVivo Image Quality Scoring (IQS) Heart Diseases, Arrhythmia, Cardiac | Completed | DiA Imaging Analysis Ltd | 164 | 2022-09-05 | 2022-10-03 | |
| Therapeutic Use of Contrast Ultrasound in Acute Coronary Artery Disease Therapeutic ultrasound with 20 usec - Acute Myocardial Infarction, Unstable Angina | Unknown | University of Sao Paulo General Hospital | 540 | 2022-02-17 | 2023-10-10 | |
| Evaluation of Safety and Efficacy of Two Ticagrelor-based De-escalation Antiplatelet Strategies in Acute Coronary Syndrome Ticagrelor 90mg, Ticagrelor 60mg, Aspirin - STEMI, NSTEMI | Phase 3 | Unknown | Collegium Medicum w Bydgoszczy | 4500 | 2022-02-07 | 2023-04-21 |
| A Cohort of Patients Undergoing Percutaneous Coronary Intervention Acute Coronary Syndrome, Percutaneous Coronary Intervention | Recruiting | Su Guohai | 10000 | 2021-12-01 | 2023-02-09 | |
| PRospective Evaluation of Complete Revascularization in Patients With multiveSsel Disease Excluding chroNic Total Occlusions PCI with OCT guidance - Multi Vessel Coronary Artery Disease, Non-ST Elevation Myocardial Infarction | Not applicable | Recruiting | Erasmus Medical Center | 609 | 2021-11-18 | 2022-02-09 |
| Physiology as Guidance to Evaluate the Direct Impact of Coronary Lesion Treatment: The PREDICT Study post-PCI FFR - Coronary Artery Disease, Stable Angina | Not applicable | Active not recruiting | Laval University | 221 | 2021-09-10 | 2025-03-19 |
| Dapagliflozin Effects on Coronary Calcium and Epicardial Fat Assessed by Cardiotomography Dapagliflozin 10Mg Tab, Placebo - Diabete Type 2, Unstable Angina | Phase 3 | Completed | Hilda Elizabeth Macías Cervantes | 54 | 2021-06-21 | 2023-08-21 |
| Fecal Microbiota and Monocyte Trained Immunity in CHD Patients With Different hsCRP take feces and blood samples from patients - Coronary Heart Disease, Unstable Angina | Completed | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 100 | 2021-05-11 | 2024-08-20 |
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Angina, Unstable (140) · Angina, Stable (52) · Acute Coronary Syndrome (48) · Myocardial Infarction (43) · Non-ST Elevated Myocardial Infarction (43) · Coronary Artery Disease (32) · ST Elevation Myocardial Infarction (23) · Myocardial Ischemia (17) · Coronary Disease (12) · Atherosclerosis (10) · Heart Failure (10) · Cardiovascular Diseases (9) · Peripheral Arterial Disease (9) · Angina Pectoris (8) · Chest Pain (8)
Neurologic Manifestations (140) · Pathological Conditions, Signs and Symptoms (140) · Pain (139) · Signs and Symptoms (139) · Vascular Diseases (139) · Heart Diseases (137) · Angina Pectoris (132) · Chest Pain (132) · Cardiovascular Diseases (131) · Myocardial Ischemia (123) · Pathologic Processes (90) · Infarction (83) · Ischemia (83) · Necrosis (83) · Arterial Occlusive Diseases (44)
Clopidogrel (6) · Percutaneous Coronary Intervention (6) · Enoxaparin (5) · Aspirin (4) · Lipid Regulating Agents (4) · Ticagrelor (4) · Atorvastatin (3) · Prasugrel Hydrochloride (3) · Rivaroxaban (3) · Hydroxymethylglutaryl-CoA Reductase Inhibitors (2) · Saline Solution (2) · Tirofiban (2) · Xue-Fu-Zhu-Yu decoction (2) · gualou xiebai banxia decoction (2) · 2'-deoxythymidylyl-(3'-5')-2'-deoxyadenosine (1)
University College, London (8) · Seoul National University Hospital (5) · Jun Li (4) · Massachusetts General Hospital (4) · CID - Carbostent & Implantable Devices (3) · Collegium Medicum w Bydgoszczy (3) · Azienda Policlinico Umberto I (2) · Biosensors Europe SA (2) · Cardio Med Medical Center (2) · Erasmus Medical Center (2) · Guang'anmen Hospital of China Academy of Chinese Medical Sciences (2) · Italian Society of Invasive Cardiology (2) · Laval University (2) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (2) · Medhub Ltd. (2)
United States (27) · South Korea (16) · Canada (15) · China (14) · Italy (12) · Netherlands (12) · United Kingdom (10) · Belgium (9) · Germany (9) · Poland (8) · Israel (6) · France (5) · Spain (5) · Brazil (4) · Romania (4)
Jun Li, MD (4) · Bon-Kwon Koo, MD, PhD (3) · Jean-Claude Tardif, MD (2) · Jeffrey M Levsky, MD, PhD (2) · Linda B Haramati, MD, MS (2) · Neville Suskin, MBChB, MSc (2) · Steven V Manoukian, MD (2) · Yong Huo, MD (2) · Aikeliyaer Ainiwaer, M.D (1) · Alan S Lader, PhD (1) · Alessandro Sciahbasi, MD (1) · Alexandra Lucas, MD (1) · Alfredo Zuppiroli, MD (1) · Amr A. Youssef, Prof doctor (1) · Anatoly Langer, MD, MSc (1)
PMID 22536282, PMID 23762142, PMID 27777598, PMID 23737852, PMID 25254054, PMID 22483327, PMID 11239408, PMID 12595860, PMID 15238590, PMID 16304073, PMID 17010793, PMID 17124018, PMID 17145253, PMID 17174178, PMID 17299194, PMID 17368152, PMID 17631219, PMID 18056903, PMID 18196350, PMID 18227366, PMID 18287598, PMID 18440330, PMID 18502300, PMID 19022155, PMID 19064681, PMID 19171852, PMID 19298914, PMID 19458363, PMID 19460609, PMID 19463332, PMID 19463378, PMID 19608488, PMID 19628125, PMID 19699861, PMID 20026777, PMID 20060578, PMID 20118151, PMID 20142447, PMID 20605241, PMID 20647564, PMID 20953817, PMID 20965465, PMID 21062996, PMID 21232745, PMID 21304094, PMID 21315212, PMID 21514083, PMID 21514084, PMID 21570509, PMID 21576647
1RC2HL101458-01 (1), 2018 (1), K23AT009715 (1), R01HL085328 (1)