7 completed, 5 unknown, 2 recruiting, 1 not yet recruiting. 16 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 16 | Completed 7, Unknown 5, Recruiting 2, Not yet recruiting 1, Terminated 1 |
Follow Trismus: new trials by email Literature Review of Trismus trials Research Report on Trismus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| "Effect of Preoperative Submucosal Dexamethasone on Postoperative Discomfort After Mandibular Third Molar Surgery" Dexamethasone, No intervention - Impacted Mandibular Third Molar, Postoperative Pain | Phase 4 | Not yet recruiting | Hayat Abad Medical Complex, Peshawar | 268 | 2026-05-01 | 2026-05-01 |
| Efficacy of Botox Injection of the Masticatory Muscles in Head &Neck Cancer Patients with Trismus After Radiotherapy Echo-guided Botox injection, echo-guided normal saline injection - Trismus, Head and Neck Cancer | Phase 4 | Recruiting | National Taiwan University Hospital | 120 | 2024-12-01 | 2024-12-16 |
| Submucosal Dexamethasone for Control of Post-operative Pain, Trismus, and Swelling After Mandibular Third Molar Surgery Dexamethasone, Normal Saline - Impacted Mandibular Third Molar Extraction | Phase 4 | Completed | PAEC General Hospital, Islamabad | 70 | 2024-10-01 | 2025-12-02 |
| The Effect of Dexamethasone Submucosal Injection After Surgical Extraction of Lower Impacted Third Molars on Trismus and Edema Dexamethasone Sodium Phosphate Injection, Normal Saline (Placebo) - Swelling/ Edema, Trismus | Phase 4 | Recruiting | King Abdulaziz University | 66 | 2024-02-01 | 2025-05-01 |
| Comparison of the Effects of Intraoral Postoperative Dexamethasone Applications After Mandibular Third Molar Surgery In this group, patients received 8 mg IM dexamethasone injection into the masseter muscle after impacted tooth surgery., 8 mg IM dexamethasone injection into the pterygoid cavity after impacted tooth surgery. - Wisdom Teeth, Edema Face | Phase 4 | Completed | Afyonkarahisar Health Sciences University | 20 | 2023-04-28 | 2024-09-20 |
| Lornoxicam Versus Etodolac After Third Molar Surgery Lornoxicam 8 Mg Oral Tablet - Pain, Acute, Edema | Phase 4 | Completed | Kutahya Health Sciences University | 20 | 2022-07-20 | 2023-01-11 |
| Different Oral Doses of Clindamycin in Preventing Post-operative Sequelae of Lower Third Molar Surgery Dalacin C - Impacted Third Molar Tooth, Impacted Molar | Phase 4 | Unknown | Oral and Maxillofacial Surgery Clinic, Poland | 300 | 2020-02-01 | 2022-03-07 |
| Comparison of Hyaluronidase and Dexametasone in Reduction of Postoperative Edema Hyaluronidase Injection mesomedica, Dexamethasone dekort - Edema, Pain | Phase 4 | Completed | Hacettepe University | 60 | 2019-12-01 | 2022-07-20 |
| The Efficacy of A-PRF+ on Postoperative Outcomes Following Surgical Removal of Impacted Mandibular Third Molars (A-PRF+: Advanced Platelet Rich Fibrin) A-PRF+ - PRF | Phase 4 | Completed | University of Medicine and Pharmacy at Ho Chi Minh City | 76 | 2019-10-01 | 2023-04-24 |
| Is Therapeutic Elastic Bandage As Effective As Corticosteroids Following Third Molar Surgery? Dexketoprofen Trometamol, Dexamethasone 21-Phosphate, Therapeutic Elastic Bandage - Third Molar Surgery | Phase 4 | Completed | Tokat Gaziosmanpasa University | 52 | 2019-05-02 | 2019-12-17 |
| Evaluation of the Effects of Pre-operative Deflazacort on Post-operative Pain, Edema and Trismus Deflazacort 30 MG Oral Tablet, Sugar pill - Impacted Third Molar Tooth | Phase 4 | Unknown | Yuzuncu Yil University | 35 | 2018-12-15 | 2023-08-22 |
| Topical Arnica and Mucopolysaccharide Polysulfate on Postoperative Pain, Edema and Trismus : Arnica montana, Mucopolysaccharide polysulfate, Control group - Impacted Third Molar Tooth | Phase 4 | Completed | Abant Izzet Baysal University | 60 | 2018-12-01 | 2020-09-01 |
| Evaluation of the Effects of Irrigation of the Extraction Socket With Rifamycine Rifamycine, Saline Solution - Impacted Third Molar Tooth | Phase 4 | Unknown | Yuzuncu Yil University | 35 | 2018-11-15 | 2023-08-22 |
| Efficacy Evaluation of the (Serodase 5 mg Tablet) in the Treatment of Inflammation After Third Molar Surgery Serodase 5 mg, Placebo - Trismus, Swelling | Phase 4 | Unknown | Hayat Pharmaceutical Co. PLC | 112 | 2015-06-01 | 2015-07-09 |
| Comparing Pain and Swelling After Surgical Extraction of Mandibular Third Molar in Dexamethasone Injection and Without Corticosteroid Methods 21-benzyloxy-9alpha-fluoro-16alpha-methylpregna-1,4-dien-11beta,17alpha-diol-3,20-dione - Oral Health, Molar, Third | Phase 4 | Unknown | Mohammad Javad Shirani | 75 | 2013-04-01 | 2013-07-11 |
| Tetanus Immunization in Subjects With No Immunization History or With Tetanus Antibody Levels Below Protective Levels Tetanus Immune Globulin (Human), Diphtheria-Tetanus Toxoids Adsorbed - Tetanus | Phase 4 | Terminated | Grifols Therapeutics LLC | 6 | 2007-03-01 | 2016-01-20 |
Edema (9) · Pain (7) · Pain, Postoperative (4) · Tooth, Impacted (2) · Acute Pain (1) · Agnosia (1) · Head and Neck Neoplasms (1) · Infections (1) · Inflammation (1) · Surgical Wound Infection (1) · Tetanus (1) · Wound Infection (1)
Nervous System Diseases (16) · Neurologic Manifestations (16) · Neuromuscular Manifestations (16) · Pathological Conditions, Signs and Symptoms (16) · Signs and Symptoms (16) · Spasm (16) · Pathologic Processes (6) · Pain (5) · Postoperative Complications (5) · Infections (2) · Stomatognathic Diseases (2) · Tooth Diseases (2) · Bacterial Infections (1) · Bacterial Infections and Mycoses (1) · Clostridium Infections (1)
Saline Solution (3) · Dexamethasone (2) · Tablets (2) · dexamethasone 21-phosphate (2) · 21-benzyloxy-9alpha-fluoro-16alpha-methylpregna-1,4-dien-11beta,17alpha-diol-3,20-dione (1) · Arnicae flos extract (1) · Clindamycin (1) · Control Groups (1) · Etodolac (1) · Injections, Intramuscular (1) · Rifampin (1) · Rifamycins (1) · Sugars (1) · deflazacort (1) · dexketoprofen trometamol (1)
Yuzuncu Yil University (2) · Abant Izzet Baysal University (1) · Afyonkarahisar Health Sciences University (1) · Grifols Therapeutics LLC (1) · Hacettepe University (1) · Hayat Abad Medical Complex, Peshawar (1) · Hayat Pharmaceutical Co. PLC (1) · King Abdulaziz University (1) · Kutahya Health Sciences University (1) · Mohammad Javad Shirani (1) · National Taiwan University Hospital (1) · Oral and Maxillofacial Surgery Clinic, Poland (1) · PAEC General Hospital, Islamabad (1) · Tokat Gaziosmanpasa University (1) · University of Medicine and Pharmacy at Ho Chi Minh City (1)
Turkey (Türkiye) (7) · Cyprus (1) · Iran (1) · Pakistan (1) · Poland (1) · Saudi Arabia (1) · Taiwan (1) · United States (1) · Vietnam (1)
Anna Janas-Naze, DMD,PhD,Prof (1) · Bijan Movahedian, Oral and maxillofacial surgeon (1) · Dr Kanza Ateeque, BDS (1) · Kumar Alagappan, MD (1) · Nihat Akbulut, Assoc. Dr. (1)
PMID 21845387, PMID 23512235, PMID 2469747, PMID 25853044, PMID 26910697, PMID 32803439, PMID 32855917, PMID 32919832, PMID 32950350, PMID 33653320, PMID 34447785, PMID 34713808, PMID 35027927, PMID 37913818, PMID 39215323, PMID 40181005, PMID 42816859, PMID 7613277