18 completed, 5 unknown, 3 recruiting, 2 active not recruiting. 30 Phase 3, 8 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 30 | Completed 18, Unknown 5, Recruiting 3, Active not recruiting 2, Not yet recruiting 1, Terminated 1 |
| Phase 2 | 8 | Completed 6, Terminated 1, Unknown 1 |
Follow Tobacco Use: new trials by email Literature Review of Tobacco Use trials Research Report on Tobacco Use
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Optimizing Treatment of Co-occurring Smoking and Unhealthy Alcohol Use Among PWH in Nairobi, Kenya Cystine, Positively Smoke Free, Placebo - HIV, Tobacco Use | Phase 3 | Not yet recruiting | University of Chicago | 300 | 2026-07-31 | 2026-07-30 |
| Intervention to Increase Intention to Change Alcohol/Tobacco Use in Veterans With Chronic Disease MINDSET, Usual Care - Tobacco Smoking, Alcohol-Related Disorders | Phase 3 | Recruiting | VA Office of Research and Development | 270 | 2025-10-01 | 2025-12-31 |
| V+PSF-M for Tobacco Cessation in HIV Care in India Varenicline, Positively Smoke Free Mobile (PSF-M), Standard Care - Human Immunodeficiency Virus, Smoking Cessation | Phase 3 | Recruiting | University of Colorado, Denver | 400 | 2024-01-02 | 2025-06-15 |
| Motivational Interviewing and Mindfulness-Oriented Recovery Enhancement MORE and MI and NRT, MORE and No MI and NRT, Support Group and MI and NRT - Polysubstance Abuse, Opioid Use | Phase 3 | Recruiting | Rutgers, The State University of New Jersey | 420 | 2023-09-05 | 2026-07-17 |
| Optimizing Tobacco Use Treatment for PLWHA Varenicline, Nicotine patch, Standard treatment - HIV/AIDS, Nicotine Dependence | Phase 3 | Active not recruiting | Abramson Cancer Center at Penn Medicine | 340 | 2020-02-17 | 2026-09-04 |
| COMET2 Project 1 Filter Ventilation Study Ventilated cigarettes only, Unventilated cigarettes only, Access to Experimental Marketplace: Ventilated cigarettes + alternative nicotine delivery systems - Smoking, Tobacco Use | Phase 3 | Completed | Masonic Cancer Center, University of Minnesota | 118 | 2018-10-18 | 2022-04-29 |
| Randomized Trial of Electronic Cigarettes With or Without Nicotine in Smoking Cessation. Electronic cigarette without nicotine (ECwN) plus active varenicline tablets, Electronic cigarette without nicotine (ECwoN) plus placebo tablets of varenicline, Electronic cigarette with nicotine (ECwN) plus placebo tablets of varenicline - Smoking Cessation, Smoking, Cigarette | Phase 3 | Active not recruiting | Assistance Publique - Hôpitaux de Paris | 650 | 2018-10-17 | 2025-12-29 |
| Curcumin; Rose Bengal; Denture Stomatitis Curcumin, Rose Bengal, Nystatin - Candida Albicans Infection, Cigarette Smoking | Phase 3 | Unknown | King Saud University | 45 | 2018-07-03 | 2021-04-08 |
| Impact of Very Low Nicotine Content Cigarettes in a Complex Marketplace Very Low Nicotine Content Cigarettes, Normal Nicotine Content Cigarettes - Tobacco Smoking, Nicotine Dependence | Phase 3 | Completed | University of Minnesota | 799 | 2018-06-01 | 2024-08-20 |
| EVarQuit: Extended Pre-quit Varenicline to Assist in Quitting Smoking Varenicline, Brief smoking cessation counseling - Tobacco Smoking | Phase 3 | Completed | State University of New York at Buffalo | 320 | 2017-10-01 | 2025-09-26 |
| Studying Partial-agonists for Ethanol and Tobacco Elimination in Russians With HIV (St PETER HIV) Varenicline, Cytisine, Nicotine Replacement Therapy - HIV Infection, Alcohol Use | Phase 2 / Phase 3 | Completed | Boston Medical Center | 400 | 2017-07-19 | 2020-12-17 |
| The Lung Screening, Tobacco and Health Project Intensive Telephone Counseling (8 sessions) with nicotine replacement, Usual Care: Telephone counseling (3 sessions) with nicotine replacement - Smoking, Tobacco, Tobacco-Related Carcinoma | Phase 3 | Completed | Georgetown University | 1114 | 2017-05-03 | 2023-11-02 |
| Pictorial Warning Labels and Memory for Cigarette Health-risk Information Over Time Text-only PWL, Low-emot PWL, High-emot PWL - Smoking Cessation, Smoking, Cigarette | Phase 3 | Completed | Ohio State University | 4424 | 2015-04-17 | 2017-12-18 |
| Dissemination of a Tailored Tobacco Quitline for Rural Veteran Smokers Nicotine replacement therapy - Transdermal nicotine patch, Nicotine replacement therapy - Nicotine gum, Nicotine replacement therapy - Nicotine lozenge - Nicotine Dependence, Tobacco Use | Phase 3 | Unknown | Mark Vander Weg | 411 | 2013-07-01 | 2017-07-11 |
| N-acetylcysteine for Tobacco Smoking N-acetylcysteine - Tobacco Smoking, Oxidative Stress | Phase 3 | Unknown | Universidade Estadual de Londrina | 32 | 2013-02-01 | 2014-04-28 |
| Tailored Smoking Cessation Treatment for LIVE FOR LIFE® Participants varenicline (Chantix), bupropion (Zyban), nicotine patches - Cigarette Smoking, Nicotine Dependence | Phase 2 / Phase 3 | Terminated | Duke University | 19 | 2012-05-01 | 2014-12-24 |
| Mechanistic Evaluations of Pre-Cessation Therapies for Smoking Cessation Varenicline, Bupropion, Nicotine patches - Nicotine Dependence | Phase 3 | Completed | Duke University | 282 | 2011-07-01 | 2017-11-14 |
| Concurrent Bupropion / Varenicline for Smoking Cessation Varenicline, Bupropion, Nicotine patches - Nicotine Dependence | Phase 3 | Completed | Duke University | 702 | 2011-03-01 | 2014-08-06 |
| Testing Counseling Styles to Motivate Smokers to Quit Brief Advice (BA), Motivational Interviewing (MI), Health Education (HE) - Smoking, Tobacco Use | Phase 3 | Completed | University of Missouri, Kansas City | 255 | 2010-10-01 | 2012-07-04 |
| Highdose Nicotine Patch Therapy for Smokeless Tobacco Use nicotine replacement therapy (nicotine patches), placebo NRT - Smokeless Tobacco Use | Phase 2 / Phase 3 | Completed | Mayo Clinic | 52 | 2010-07-01 | 2014-05-19 |
Showing 20 of 30. Sign in to see all of them.
Smoking Cessation (12) · Tobacco Use Disorder (12) · Cigarette Smoking (11) · Tobacco Smoking (7) · Smoking (5) · Alcohol Drinking (3) · Tobacco Use Cessation (3) · Acquired Immunodeficiency Syndrome (2) · Inflammation (2) · Alcohol-Related Disorders (1) · Alcoholism (1) · Behavior (1) · Body Weight (1) · Chronic Disease (1)
Behavior (29) · Smoking (15) · Chemically-Induced Disorders (14) · Health Behavior (14) · Mental Disorders (14) · Substance-Related Disorders (14) · Tobacco Smoking (11) · Pathological Conditions, Signs and Symptoms (4) · Blood-Borne Infections (3) · Communicable Diseases (3) · Drinking Behavior (3) · Genital Diseases (3) · Immune System Diseases (3) · Immunologic Deficiency Syndromes (3)
Varenicline (9) · Tobacco Use Cessation Devices (8) · Bupropion (4) · Nicotine (4) · Nicotine Replacement Therapy (3) · Standard of Care (3) · Motivational Interviewing (2) · 3-azido-2,7-naphthalene disulfonate (1) · Acetylcysteine (1) · Counseling (1) · Crisis Intervention (1) · Curcumin (1) · Cystine (1) · Educational Status (1) · Electronic Nicotine Delivery Systems (1)
Duke University (4) · Mayo Clinic (4) · Abramson Cancer Center at Penn Medicine (1) · Assistance Publique - Hôpitaux de Paris (1) · Boston Medical Center (1) · Georgetown University (1) · Kaiser Permanente (1) · Karolinska Institutet (1) · King Saud University (1) · Mark Vander Weg (1) · Masonic Cancer Center, University of Minnesota (1) · Ohio State University (1) · Rutgers, The State University of New Jersey (1) · State University of New York at Buffalo (1) · Tata Memorial Hospital (1)
United States (21) · India (2) · Brazil (1) · Denmark (1) · France (1) · Kenya (1) · Russia (1) · Saudi Arabia (1) · Sweden (1)
Jed E Rose, Ph.D. (3) · Jon O Ebbert, MD (2) · Amit Sood, M.D. (1) · Asgeir R Helgason, PhD (1) · Delwyn Catley, Ph.D. (1) · Dorothy Hatsukami, PHD (1) · Dorothy K Hatsukami, Ph.D (1) · F. Joseph McClernon, Ph.D. (1) · Gina Kruse, MD (1) · Jack F Hollis, Ph.D. (1) · Jeffrey H Samet, MA, MA, MPH (1) · Jennifer S Funderburk, PhD (1) · Julie Christina Gass, PhD (1) · Lars Forsberg, PhD (1) · Lori Pbert, PhD (1)
PMID 37142273, PMID 17852172, PMID 18608316, PMID 20379614, PMID 20811658, PMID 22007015, PMID 22713093, PMID 23454876, PMID 23873976, PMID 24934962, PMID 26711164, PMID 27081187, PMID 29895280, PMID 29947729, PMID 31129603, PMID 31466882, PMID 33219852, PMID 33868901, PMID 33878020, PMID 33964415, PMID 34077535, PMID 34611902, PMID 35143041, PMID 35448154, PMID 35818122, PMID 35818125, PMID 35906990, PMID 35930287, PMID 36367720, PMID 37230961, PMID 37347538, PMID 38911348, PMID 40701191, PMID 40720285, PMID 41352530, PMID 41852246
P50DA027840 (2), 2005 (1), 2017 (1), P50CA180908 (1), R01CA098685 (1), R01CA133068 (1), R01CA206193 (1), R01CA207228 (1), R01CA243914 (1), R01CA288235 (1), R01DA057631 (1), U01AA020780 (1), U01CA261614 (1)