52 completed, 14 unknown, 9 not yet recruiting, 8 recruiting. 54 Not applicable, 9 Phase 4, 4 Phase 2, 3 Phase 3, 1 Phase 1.
Follow Thyroidectomy: new trials by email Literature Review of Thyroidectomy trials Research Report on Thyroidectomy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Recover@Home Postoperative Follow-up Study Recovery@home - Hernia, Inguinal, Hernia, Femoral | Not applicable | Not yet recruiting | Icahn School of Medicine at Mount Sinai | 194 | 2027-03-01 | 2026-07-20 |
| Effect of Cold Water Spray on Swallowing Difficulty, Pain, and Thirst After Thyroid Surgery Cold water spray - Swallowing Difficulties, Thirst | Not applicable | Enrolling by invitation | Saglik Bilimleri Universitesi Gulhane Tip Fakultesi | 108 | 2026-10-12 | 2026-10-20 |
| Comparing Medial and Lateral Dissection Approaches to the Recurrent Laryngeal Nerve During a Thyroidectomy Approach to RLN during Thyroidectomy - Thyroidectomy | Not applicable | Not yet recruiting | Oleksandr Butskiy | 430 | 2026-09-01 | 2026-08-31 |
| The Effect of Bilateral Intermediate Cervical Plexus Block on the Surgical Stress Response Following Total Thyroidectomy Ultrasound-Guided Bilateral Intermediate Cervical Plexus Block Using 0,25% Levobupivacaine - Thyroidectomy, Cervical Plexus Block | Phase 4 | Not yet recruiting | University Hospital Dubrava | 48 | 2026-08-15 | 2026-08-07 |
| Effects of Dexmedetomidine Combined With Lidocaine Topical Administration on Cough Reflex During Extubation in Thyroidectomy Patient. · Dex-Lido solution: Dexmedetomidine 100 μg/mL (concentration) was diluted with 2% lidocaine to achieve final concentration of dexmedetomidine 1 μg/kg in 5 mL total volume, · Lido solution: 2% lidocaine, 5 mL, · Control solution: 0.9% normal saline, 5 mL - Cough Suppression, Thyroidectomy | Not applicable | Active not recruiting | Sohag University | 120 | 2026-07-01 | 2026-09-21 |
| The Effect of Esketamine on Cough Reflex During Tracheal Extubation in Patients Undergoing Open Thyroid Surgery Esketamine, Normal Saline - Thyroidectomy, Coughing Reflex | Not applicable | Not yet recruiting | The Second Hospital of Anhui Medical University | 136 | 2026-06-01 | 2026-06-04 |
| The Effect of Esketamine on Cough Reflex During Tracheal Extubation in Patients Undergoing Non-inflatable Transoral Endoscopic Thyroid Surgery Esketamine（iv）, ESK spray, Normal Saline - Thyroidectomy, Coughing Reflex | Not applicable | Not yet recruiting | The Second Hospital of Anhui Medical University | 186 | 2026-06-01 | 2026-06-11 |
| NIRAF-Guided Parathyroid Identification During Thyroidectomy Wearable Near-Infrared Autofluorescence Imaging System - Hypocalcemia, Hypoparathyroidism | Not applicable | Not yet recruiting | Ss. Cyril and Methodius University of Skopje | 280 | 2026-06-01 | 2026-06-01 |
| Nurse-Led First-Night Preparation After Thyroidectomy Nurse-Led First-Night Preparation Intervention - Thyroidectomy | Not applicable | Completed | Volkan Gokmen | 44 | 2026-05-15 | 2026-09-30 |
| The Role of Prophylactic Central Compartment Neck Dissection in the Management of 2 to 4 cm Papillary Thyroid Carcinoma Total Thyroidectomy + Central Compartment Neck Dissection, Thyroid Lobectomy + ipCCND - Papillary Thyroid Carcinoma, Central Compartment Neck Dissction | Not applicable | Not yet recruiting | Leonardo Rossi | 392 | 2026-04-28 | 2026-05-05 |
| Opioid-Free Versus Opioid-Based Anesthesia in Thyroid Surgery Fentanyl (IV), Dexmedetomidine and lidocaine - Thyroidectomy, Oxidative Stress | Not applicable | Recruiting | Malatya Egitim Ve Arastirma Hastanesi | 110 | 2026-04-01 | 2026-10-07 |
| Effects of Flurbiprofen Spray and Ice Cream for Pain and Voice Outcomes After Thyroidectomy Flurbiprofen, Food Effect cohort, Placebo Control - Thyroidectomy, Sore Throat | Phase 4 | Not yet recruiting | Izmir Katip Celebi University | 100 | 2026-04-01 | 2026-04-15 |
| LigaSure vs Bipolar Diathermy in Thyroidectomy LigaSure, bipolar diathermy, Thyroidectomy - Thyroidectomy | Not applicable | Not yet recruiting | Assiut University | 30 | 2025-12-01 | 2025-12-10 |
| TOETVA Technique Compared With Anterior Cervical Thyroidectomy (AC) in Terms of Efficacy and Safety Transoral Endoscopic Thyroidectomy by Vestibular Approach, Anterior Cervical thyroidectomy - Lobectomy, Thyroidectomy | Not applicable | Recruiting | University Hospital, Lille | 616 | 2025-11-07 | 2026-01-16 |
| Water Based Burpee Exercises on Functional Capacity in Poste-menopausal Women After Thyroidectomy water based burpee exercises, aerobic exercises - Burpee Exercise, Water Exercises | Not applicable | Recruiting | Al-Zaytoonah University of Jordan | 40 | 2025-09-01 | 2025-11-19 |
| Ketamine Versus Dexmedetomidine as Adjuvants to Bupivacaine in Ultrasound Guided Bilateral Superficial Cervical Plexus Block in Thyroidectomy Group C (Control group), Group D (Dexmedetomidine group), Group K (Ketamine group) - Thyroidectomy, Bupivacaine | Not applicable | Completed | Tanta University | 60 | 2025-08-31 | 2026-10-06 |
| Safety and Efficacy of NTP in Thyroid Surgery: Pilot Study on Morbidity Prevention and Adjuvant Oncological Control Atmospheric Pressure Non-Thermal Plasma, Standard Surgical Wound Care Protocol - Thyroid Diseases, Wound Healing | Not applicable | Recruiting | National Institute of Nuclear Research - Mexico | 26 | 2025-08-20 | 2026-02-09 |
| RECURRENT LARYNGEAL INJURY WHILE USING LIGASURE Versus CONVENTIONAL KNOT TYING IN TOTAL THYROIDECTOMY tie and knot, Ligasure - Thyroidectomy | Not applicable | Completed | Gulab Devi Hospital | 120 | 2025-07-07 | 2026-04-13 |
| Thyroidectomy for Graves' Disease or Amiodarone-induced Thyrotoxicosis Graves Disease, Amiodarone-Induced Thyrotoxicosis | Recruiting | Andrea Goldmann | 486 | 2025-07-01 | 2025-07-02 | |
| Cervical Erector Spinae Plane Block vs Cervical Plexus Block in Controlling Acute Postoperative Pain After Thyroidectomy Cervical erector spinae plane block, Cervical plexus block - Cervical, Erector Spinae Plane Block | Not applicable | Completed | Cairo University | 40 | 2025-05-15 | 2025-12-29 |
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Thyroid Diseases (10) · Pain, Postoperative (7) · Thyroid Neoplasms (5) · Hypocalcemia (4) · Hypoparathyroidism (4) · Pain (4) · Thyroid Cancer, Papillary (4) · Hernia, Inguinal (3) · Deglutition Disorders (2) · Dysphonia (2) · Patient Satisfaction (2) · Pharyngitis (2) · Postoperative Nausea and Vomiting (2) · Vomiting (2) · Adenolymphoma (1)
Endocrine System Diseases (26) · Pathological Conditions, Signs and Symptoms (22) · Signs and Symptoms (18) · Neurologic Manifestations (17) · Thyroid Diseases (11) · Neoplasms (10) · Pathologic Processes (10) · Endocrine Gland Neoplasms (9) · Head and Neck Neoplasms (9) · Neoplasms by Site (9) · Pain (9) · Postoperative Complications (8) · Otorhinolaryngologic Diseases (7) · Nervous System Diseases (6) · Respiratory Tract Diseases (6)
Thyroidectomy (8) · Saline Solution (5) · Lidocaine (4) · Remifentanil (3) · Acetaminophen (2) · Dexamethasone (2) · Dexmedetomidine (2) · Sodium Chloride (2) · Bupivacaine (1) · Celecoxib (1) · Cervical Plexus Block (1) · Congresses as Topic (1) · Control Groups (1) · Cryotherapy (1) · Educational Status (1)
Yonsei University (4) · Aristotle University Of Thessaloniki (3) · Seoul National University Hospital (3) · Assiut University (2) · Bo Wang,MD (2) · Cantonal Hospital of St. Gallen (2) · Fujian Medical University (2) · Hippocration General Hospital (2) · Inje University (2) · Regional Hospital West Jutland (2) · The Second Hospital of Anhui Medical University (2) · Uludag University (2) · Ain Shams University (1) · Al-Zaytoonah University of Jordan (1) · Andrea Goldmann (1)
South Korea (14) · Turkey (Türkiye) (13) · China (8) · Greece (7) · France (6) · United States (6) · Egypt (5) · Taiwan (4) · Denmark (3) · Italy (3) · Pakistan (3) · Switzerland (3) · Belgium (1) · Ireland (1) · Mexico (1)
Thomas Clerici, MD (2) · Ali Ahiskalioglu, Ass.Prof. (1) · Andrea Goldmann, MD (1) · Andreas Manouras, MD, PhD (1) · Andreas Manouras, PhD (1) · Antonios Michalopoulos, Professor (1) · Awais Amjad Malik, MBBS, FCPS (1) · Burcu Demir Gokmen (1) · Chao-Chun Huang (1) · Christian Godballe, Doctor (1) · Claire Texier, Dr (1) · Dimitrios Zacharoulis, As Professor (1)
PMID 11222424, PMID 12095591, PMID 17573619, PMID 19092351, PMID 19177420, PMID 20632263, PMID 21469244, PMID 24015953, PMID 25563879, PMID 25699129, PMID 25809677, PMID 26158868, PMID 26667156, PMID 27106003, PMID 28403427, PMID 28643050, PMID 29049468, PMID 29468508, PMID 31511942, PMID 31538057, PMID 33211953, PMID 34043775, PMID 35637354, PMID 36040827, PMID 37194813, PMID 38573333, PMID 40034788, PMID 40613790, PMID 9602010
R21TW012963 (1), R25DC020174 (1)