18 completed, 5 recruiting, 3 not yet recruiting, 1 active not recruiting. 20 Not applicable, 2 Phase 4, 1 Phase 1, 1 Phase 2, 1 Phase 3.
Follow Stress Response: new trials by email Literature Review of Stress Response trials Research Report on Stress Response
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cranberry Polyphenols and Stress Resilience During Multitasking in Healthy Adults Cranberry juice, Placebo juice - Stress Response, Mental Stress | Not applicable | Recruiting | University of Florida | 84 | 2026-08-01 | 2026-06-30 |
| Video Versus Verbal Preoperative Education in Elective Cesarean Delivery Video-Based Preoperative Education, Verbal Preoperative Education - Preoperative Anxiety, Cesarean Delivery | Not applicable | Completed | Elazıg Fethi Sekin Sehir Hastanesi | 140 | 2026-04-02 | 2026-09-11 |
| Effect of Stress Ball Use on Pain, Anxiety, and Vital Signs During Ultrasound-Guided Tru-cut Biopsy Behavioral: Stress Ball Application - Procedural Pain, Anxiety | Not applicable | Completed | Istanbul University | 79 | 2026-03-15 | 2026-05-29 |
| Transcutaneous Vagus Nerve Stimulation (tVNS) and Stress Regulation During Performance Tasks Transcutaneous Vagus Nerve Stimulation (tVNS), Evaluative Stress Task - Stress Response | Not applicable | Not yet recruiting | University of Florida | 200 | 2026-03-15 | 2026-03-13 |
| Comparison of Stress Response Evoked by Conventional Versus Videolaryngoscope Endotracheal Intubation through a Video Laryngoscope (VL), Endotracheal Intubation through a Direct Laryngoscope (DL) - Laryngoscopy, Stress Response | Not applicable | Recruiting | Sindh Institute of Urology and Transplantation | 124 | 2026-03-05 | 2026-04-03 |
| Do Increasing Preoperative Timing of Single Dexmedetomidine Dose Have an Effect on Stress Response of Laryngoscopy and Intubation? Dexmedetomidine, Saline - Time, Dexmedetomidine | Not applicable | Recruiting | Tanta University | 45 | 2025-09-11 | 2025-09-12 |
| Effect of Nebulized Lignocaine on the Stress Response of Endotracheal Intubation in Pediatrics Undergoing Tonsillectomy Operation Monitored by Rise in Serum Cortisol Level Post Intubation Lignocaine 2% concentration solution - Stress Response | Not applicable | Not yet recruiting | Assiut University | 70 | 2025-09-01 | 2025-08-24 |
| The Impact Opioid Free Anesthesia on Postoperative Pain Intensity and Stress Response After Open Gynecology Surgery OFA group - Opioid Free Anesthesia, Stress Response | Not applicable | Active not recruiting | Cantonal Hospital Zenica | 80 | 2025-07-17 | 2025-08-22 |
| Survey of Psychological Well-being of Health Care Workers in the Hospital Setting Psychological Assessment - Healthy, Psychological Well Being | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 500 | 2025-04-01 | 2025-04-27 | |
| Impact of OnabotulinumtoxinA (BOTOX®) on Stress Intramuscular injection, OnabotulinumtoxinA (Botox®) Injections, Sodium Chloride - Stress (Psychology), Stress | Phase 1 | Completed | Center for Advanced Facial Plastic Surgery | 4 | 2025-03-19 | 2026-04-29 |
| Stress Trajectories and Anhedonia in Adolescence Research Study Montreal Imaging Stress Task, Trier Social Stress Test for Children - Anhedonia, Stress Response | Not applicable | Recruiting | University of North Carolina, Chapel Hill | 192 | 2025-03-12 | 2026-08-17 |
| Effect of Dexmedetomidine Supplementation to General Anaesthesia in Paediatric Transcatheter Closure of Atrial Septal Defect Dexmedetomidine, Saline (NaCl 0,9 %) (placebo) - Atrial Septal Defect (ASD), Dexmedetomidine | Phase 4 | Recruiting | Alexandria University | 30 | 2024-04-03 | 2024-10-15 |
| Can Cranberry Juice Enhance the Cognition Accuracy and Alleviate Negative Mental Consequences During Multitasking? Cranberry Juice A, Cranberry Juice B, Placebo Juice - Stress Response, Multitasking Behavior | Not applicable | Suspended | University of Florida | 126 | 2024-01-10 | 2026-07-02 |
| Analysis of Psychoneuroimmunological Parameters of Health in Specific Population Groups in Slovakia Immunity, Cytokine Levels | Completed | Comenius University | 700 | 2024-01-01 | 2026-02-19 | |
| Post-biotic Intervention for Acute Stress Management Post-biotic (Colonic-Delivery capsule), Post-biotic (Regular Administration capsule), Placebo - Stress Response, Mood State | Not applicable | Completed | Institute for Human Development and Potential (IHDP), Singapore | 75 | 2023-11-01 | 2024-08-16 |
| Stress Response and Hemodynamic Changes Associated With Intrathecal Anesthesia Versus Caudal Epidural Anesthesia in Infants Undergoing Laparoscopic Inguinal Herniorrhaphy General anesthesia, Intrathecal Anesthesia, Caudal block - Stress Response, Hemodynamic Changes | Not applicable | Completed | Tanta University | 120 | 2023-06-01 | 2025-04-03 |
| Effect of Intraoperative Music on Inflammatory Response in Donor Hepatectomy music, no music - Transplantation, Hepatectomy | Not applicable | Completed | Istinye University | 61 | 2023-05-22 | 2025-09-22 |
| Investigating Stress-Induced Dopamine Release: a fMRI-PET Study tDCS actif, tDCS Sham - Stress Response | Not applicable | Completed | Hôpital le Vinatier | 34 | 2023-04-11 | 2025-03-06 |
| Comparison of the Escape Room and Storytelling Methods in Learning the Stress Response Escape room, Storytelling - Stress Response | Not applicable | Completed | Ankara Medipol University | 35 | 2022-12-13 | 2023-05-19 |
| Effects of Erector Spinae Plane and Caudal Block on Postoperative Stress Response Ultrasound-guided erector spinae plan block, Ultrasound-guided caudal block - Post Operative Pain, Stress Response | Not applicable | Completed | Sisli Hamidiye Etfal Training and Research Hospital | 62 | 2022-12-06 | 2023-03-24 |
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Fractures, Stress (28) · Anxiety Disorders (3) · Pain, Postoperative (3) · Stress, Psychological (3) · Emergence Delirium (2) · Motor Activity (2) · Multitasking Behavior (2) · Neurobehavioral Manifestations (2) · Affective Symptoms (1) · Agnosia (1) · Aneurysm (1) · Anhedonia (1) · Burnout, Psychological (1) · Depression (1) · Diabetes Insipidus (1)
Fractures, Bone (28) · Wounds and Injuries (28) · Pathological Conditions, Signs and Symptoms (12) · Neurologic Manifestations (10) · Signs and Symptoms (10) · Pathologic Processes (7) · Nervous System Diseases (6) · Behavior (5) · Behavioral Symptoms (5) · Mental Disorders (5) · Postoperative Complications (5) · Neurobehavioral Manifestations (4) · Pain (4) · Cardiovascular Diseases (2) · Confusion (2)
Dexmedetomidine (4) · Lidocaine (3) · Sodium Chloride (3) · Anesthesia, General (1) · Botulinum Toxins, Type A (1) · Fentanyl (1) · Injections (1) · Injections, Intramuscular (1) · Music Therapy (1) · Psychological Tests (1) · esmolol (1)
University of Florida (3) · Assiut University (2) · Tanta University (2) · Alexandria University (1) · Ankara Medipol University (1) · Aydin Adnan Menderes University (1) · Cantonal Hospital Zenica (1) · Catholic University of the Sacred Heart (1) · Center for Advanced Facial Plastic Surgery (1) · Comenius University (1) · Elazıg Fethi Sekin Sehir Hastanesi (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Hôpital le Vinatier (1) · Institute for Human Development and Potential (IHDP), Singapore (1) · Istanbul University (1)
Turkey (Türkiye) (6) · Egypt (5) · United States (5) · France (2) · Bosnia and Herzegovina (1) · China (1) · India (1) · Italy (1) · Pakistan (1) · Singapore (1) · Slovakia (1) · United Kingdom (1)
Ali Sait Kavakli, M.D. (1) · Asmira Ljuca, MD (1) · Aysenil Belger, PhD (1) · Babak Azizzadeh, MD, FACS (1) · Beyza Zeynep Kocabicak (1) · Danielle Roubinov, PhD (1) · Dr. Sarath Chandra Sistla, M.S., (1) · Dustin Hegland, MD-ANESTHESIOLOGY-GENERAL (1) · Flaminio Sessa, MD (1) · Hamdy Yossef, MD (1) · Jeroen Schmitt, PhD (1) · Lewei Gu, PhD (1)
PMID 15337807, PMID 18835437, PMID 22026977, PMID 24576975, PMID 26395762, PMID 27178861, PMID 27608913, PMID 28742427, PMID 29154132, PMID 32492090, PMID 32607960, PMID 37724595, PMID 9062617
R01MH136102 (1)