12 completed, 4 recruiting, 2 not yet recruiting, 1 active not recruiting. 20 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 20 | Completed 12, Recruiting 4, Not yet recruiting 2, Active not recruiting 1, Suspended 1 |
Follow Stress Response: new trials by email Literature Review of Stress Response trials Research Report on Stress Response
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cranberry Polyphenols and Stress Resilience During Multitasking in Healthy Adults Cranberry juice, Placebo juice - Stress Response, Mental Stress | Not applicable | Recruiting | University of Florida | 84 | 2026-08-01 | 2026-06-30 |
| Video Versus Verbal Preoperative Education in Elective Cesarean Delivery Video-Based Preoperative Education, Verbal Preoperative Education - Preoperative Anxiety, Cesarean Delivery | Not applicable | Completed | Elazıg Fethi Sekin Sehir Hastanesi | 140 | 2026-04-02 | 2026-09-11 |
| Effect of Stress Ball Use on Pain, Anxiety, and Vital Signs During Ultrasound-Guided Tru-cut Biopsy Behavioral: Stress Ball Application - Procedural Pain, Anxiety | Not applicable | Completed | Istanbul University | 79 | 2026-03-15 | 2026-05-29 |
| Transcutaneous Vagus Nerve Stimulation (tVNS) and Stress Regulation During Performance Tasks Transcutaneous Vagus Nerve Stimulation (tVNS), Evaluative Stress Task - Stress Response | Not applicable | Not yet recruiting | University of Florida | 200 | 2026-03-15 | 2026-03-13 |
| Comparison of Stress Response Evoked by Conventional Versus Videolaryngoscope Endotracheal Intubation through a Video Laryngoscope (VL), Endotracheal Intubation through a Direct Laryngoscope (DL) - Laryngoscopy, Stress Response | Not applicable | Recruiting | Sindh Institute of Urology and Transplantation | 124 | 2026-03-05 | 2026-04-03 |
| Do Increasing Preoperative Timing of Single Dexmedetomidine Dose Have an Effect on Stress Response of Laryngoscopy and Intubation? Dexmedetomidine, Saline - Time, Dexmedetomidine | Not applicable | Recruiting | Tanta University | 45 | 2025-09-11 | 2025-09-12 |
| Effect of Nebulized Lignocaine on the Stress Response of Endotracheal Intubation in Pediatrics Undergoing Tonsillectomy Operation Monitored by Rise in Serum Cortisol Level Post Intubation Lignocaine 2% concentration solution - Stress Response | Not applicable | Not yet recruiting | Assiut University | 70 | 2025-09-01 | 2025-08-24 |
| The Impact Opioid Free Anesthesia on Postoperative Pain Intensity and Stress Response After Open Gynecology Surgery OFA group - Opioid Free Anesthesia, Stress Response | Not applicable | Active not recruiting | Cantonal Hospital Zenica | 80 | 2025-07-17 | 2025-08-22 |
| Stress Trajectories and Anhedonia in Adolescence Research Study Montreal Imaging Stress Task, Trier Social Stress Test for Children - Anhedonia, Stress Response | Not applicable | Recruiting | University of North Carolina, Chapel Hill | 192 | 2025-03-12 | 2026-08-17 |
| Can Cranberry Juice Enhance the Cognition Accuracy and Alleviate Negative Mental Consequences During Multitasking? Cranberry Juice A, Cranberry Juice B, Placebo Juice - Stress Response, Multitasking Behavior | Not applicable | Suspended | University of Florida | 126 | 2024-01-10 | 2026-07-02 |
| Post-biotic Intervention for Acute Stress Management Post-biotic (Colonic-Delivery capsule), Post-biotic (Regular Administration capsule), Placebo - Stress Response, Mood State | Not applicable | Completed | Institute for Human Development and Potential (IHDP), Singapore | 75 | 2023-11-01 | 2024-08-16 |
| Stress Response and Hemodynamic Changes Associated With Intrathecal Anesthesia Versus Caudal Epidural Anesthesia in Infants Undergoing Laparoscopic Inguinal Herniorrhaphy General anesthesia, Intrathecal Anesthesia, Caudal block - Stress Response, Hemodynamic Changes | Not applicable | Completed | Tanta University | 120 | 2023-06-01 | 2025-04-03 |
| Effect of Intraoperative Music on Inflammatory Response in Donor Hepatectomy music, no music - Transplantation, Hepatectomy | Not applicable | Completed | Istinye University | 61 | 2023-05-22 | 2025-09-22 |
| Investigating Stress-Induced Dopamine Release: a fMRI-PET Study tDCS actif, tDCS Sham - Stress Response | Not applicable | Completed | Hôpital le Vinatier | 34 | 2023-04-11 | 2025-03-06 |
| Comparison of the Escape Room and Storytelling Methods in Learning the Stress Response Escape room, Storytelling - Stress Response | Not applicable | Completed | Ankara Medipol University | 35 | 2022-12-13 | 2023-05-19 |
| Effects of Erector Spinae Plane and Caudal Block on Postoperative Stress Response Ultrasound-guided erector spinae plan block, Ultrasound-guided caudal block - Post Operative Pain, Stress Response | Not applicable | Completed | Sisli Hamidiye Etfal Training and Research Hospital | 62 | 2022-12-06 | 2023-03-24 |
| Effects of Voice Records on Patient Outcomes Surgical Intensive Care Unit Voice recording playback - Intensive Care Unit Patients, Pain Management | Not applicable | Completed | Aydin Adnan Menderes University | 69 | 2021-05-01 | 2025-06-06 |
| Effect of Dexmedetomidine vs Esmolol or Placebo on Cerebral Hemodynamics in Septic Shock Dexmedetomidine Hydrochloride, Esmolol Hydrochloride - Septic Shock, Stress Response | Not applicable | Completed | Xinchen Wang | 14 | 2020-11-01 | 2023-12-13 |
| Magnesium Versus High Dose Fentanyl in Endotracheal Intubation Magnesium sulfate- Fentanyl, Fentanyl 4Mcg/kg, Fentanyl 2Mcg/kg - Stress Response | Not applicable | Completed | National Cancer Institute, Egypt | 160 | 2020-09-05 | 2021-05-11 |
| Remifentanil and Stress Hormones Response Remifentanil Injectable Product - Stress Response | Not applicable | Completed | Catholic University of the Sacred Heart | 50 | 2008-01-01 | 2018-01-08 |
Fractures, Stress (20) · Anxiety Disorders (2) · Motor Activity (2) · Multitasking Behavior (2) · Neurobehavioral Manifestations (2) · Pain, Postoperative (2) · Stress, Psychological (2) · Agnosia (1) · Anhedonia (1) · Pain, Procedural (1) · Shock, Septic (1)
Fractures, Bone (20) · Wounds and Injuries (20) · Pathological Conditions, Signs and Symptoms (8) · Neurologic Manifestations (7) · Signs and Symptoms (7) · Nervous System Diseases (4) · Pain (3) · Pathologic Processes (3) · Behavior (2) · Behavioral Symptoms (2) · Mental Disorders (2) · Neurobehavioral Manifestations (2) · Postoperative Complications (2) · Infections (1) · Inflammation (1)
Dexmedetomidine (2) · Lidocaine (2) · Anesthesia, General (1) · Fentanyl (1) · Music Therapy (1) · Psychological Tests (1) · Sodium Chloride (1) · esmolol (1)
University of Florida (3) · Tanta University (2) · Ankara Medipol University (1) · Assiut University (1) · Aydin Adnan Menderes University (1) · Cantonal Hospital Zenica (1) · Catholic University of the Sacred Heart (1) · Elazıg Fethi Sekin Sehir Hastanesi (1) · Hôpital le Vinatier (1) · Institute for Human Development and Potential (IHDP), Singapore (1) · Istanbul University (1) · Istinye University (1) · National Cancer Institute, Egypt (1) · Sindh Institute of Urology and Transplantation (1) · Sisli Hamidiye Etfal Training and Research Hospital (1)
Turkey (Türkiye) (6) · United States (4) · Egypt (3) · Bosnia and Herzegovina (1) · China (1) · France (1) · Italy (1) · Pakistan (1) · Singapore (1)
Ali Sait Kavakli, M.D. (1) · Asmira Ljuca, MD (1) · Aysenil Belger, PhD (1) · Beyza Zeynep Kocabicak (1) · Danielle Roubinov, PhD (1) · Dustin Hegland, MD-ANESTHESIOLOGY-GENERAL (1) · Flaminio Sessa, MD (1) · Jeroen Schmitt, PhD (1) · Lewei Gu, PhD (1) · Nahla N Shehab, MD (1) · Syed M Abbas (1) · Taylan Sahin, M.D. (1)
PMID 27178861, PMID 27608913, PMID 28742427, PMID 29154132, PMID 32607960, PMID 37724595, PMID 9062617
R01MH136102 (1)