29 completed, 4 recruiting, 3 withdrawn, 1 terminated. 38 Phase 2, 5 Phase 1, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 38 | Completed 29, Recruiting 4, Withdrawn 3, Terminated 1, Unknown 1 |
| Phase 1 | 5 | Completed 4, Recruiting 1 |
| Phase 3 | 3 | Completed 1, Recruiting 1, Unknown 1 |
Follow Stress: new trials by email Literature Review of Stress trials Research Report on Stress
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intranasal Oxytocin Intervention for Caregivers to Persons With Dementia Placebo, Oxytocin Intranasal Spray 12 International Unit (12IU), Oxytocin Intranasal Spray 24 International Unit (24IU) - Stress | Phase 2 | Recruiting | University of Nebraska | 32 | 2026-12-20 | 2026-11-02 |
| Sleep and Stress Study Lavender Oil, Palmitoylethanolamide (PEA), Oleoylethanolamide - Sleep Disorder (Disorder), Stress | Phase 2 | Recruiting | RDC Clinical Pty Ltd | 240 | 2026-04-07 | 2026-04-23 |
| Study of Cannabidiol and Neuroimaging on Stress Cannabidiol, Placebo - Early Life Adversity, Trauma | Phase 1 / Phase 2 | Recruiting | Icahn School of Medicine at Mount Sinai | 160 | 2025-10-29 | 2026-09-10 |
| Investigating the Protective Impact of LY-2940094 on Stress-induced Depression- and Anxiety-related Phenotypes in Humans Nociceptin Receptor Antagonist (LY-2940094), DS8R Biphasic Constant Current Stimulator - Depression - Major Depressive Disorder, Anxiety | Phase 2 | Withdrawn | Mclean Hospital | 2025-06-01 | 2025-09-25 | |
| The Impact of Ginger Mouthwash on the Pregnant Women With Stress and Gingivitis ginger mouthwash, chlorohexidine mouthwash, Placebo - Mouth Diseases, Bleeding Gum | Phase 2 | Completed | Al-Mustansiriyah University | 45 | 2025-01-25 | 2025-07-14 |
| Personal Relevance of Psychotherapy for Asian Americans MindBoba, Mindshift CBT - Behavior, Stress | Phase 2 | Completed | IRIS Media Inc | 263 | 2024-05-01 | 2026-08-05 |
| Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder Magnesium vitamin B6, Placebo - Bipolar I Disorder, Depression, Anxiety | Phase 2 | Completed | Mclean Hospital | 22 | 2023-12-13 | 2026-11-12 |
| Effects Of A Probiotic Formulation On Stress and Skin Health in Younger Adult Females Probiotic - Stress, Skin Imperfections | Phase 2 | Completed | Lallemand Health Solutions | 35 | 2023-09-27 | 2024-02-20 |
| Using rTMS to Explore Neural Mechanisms of Stress-Induced Opioid Use Placebo oral tablet, Yohimbine + Hydrocortisone, sham rTMS - Stress, Opioid-use Disorder | Phase 2 | Withdrawn | Wayne State University | 2023-04-10 | 2023-04-13 | |
| rTMS of Limbic Circuitry in Stress Modulation in Healthy Volunteers yohimbine + hydrocortisone, medial prefrontal cortex rTMS, Placebo oral tablet - Stress, Healthy | Phase 2 | Withdrawn | Wayne State University | 2023-04-10 | 2023-04-13 | |
| The Safety and Efficacy of AlphaWave® L-Theanine on Adults Who Experience Moderate Stress on a Regular Basis AlphaWave® L-Theanine, Placebo - Stress | Phase 2 | Completed | Ethical Naturals, Inc. | 30 | 2023-04-04 | 2024-05-08 |
| The Efficacy of a Probiotic Blend on Stress in Moderately Stressed Teens Probiotic Blend, Placebo - Stress | Phase 2 | Completed | Lallemand Health Solutions | 30 | 2023-03-15 | 2024-02-22 |
| Effects of Rifaximin on Gut Microbiota and Emotion Rifaximin, Placebo - Healthy Volunteers, Stress | Phase 2 / Phase 3 | Recruiting | Universitaire Ziekenhuizen KU Leuven | 60 | 2023-02-02 | 2024-12-20 |
| Impact of Probiotic Supplementation on Cognition and Related Health Outcomes Among Video Gamers Probiotic, Placebo - Stress, Attention Disturbances | Phase 2 | Completed | Lallemand Health Solutions | 36 | 2023-01-21 | 2023-11-29 |
| The Lived Experiences Measured Using Rings Pilot Study Moodlifters, Physical Activity, Nature Experiences - Depression, Stress | Phase 2 | Completed | University of Vermont | 188 | 2022-12-01 | 2025-04-17 |
| Understanding Everyday Stress Self-monitoring and personalized stress management, Self-monitoring and general stress management - Stress, Psychological Stress | Phase 2 | Completed | Penn State University | 213 | 2022-08-15 | 2023-08-09 |
| Personalized Trials for Stress Management Against Standard of Care Personalized Trial ABCCBA, Personalized Trial CBAABC, Stress Management Techniques with No Randomization Sequence (or order) - Stress | Phase 2 | Completed | Northwell Health | 212 | 2022-06-23 | 2026-03-23 |
| The Effectiveness of a Caralluma Fimbriata Extract on Stress, Sleep and Neurotransmitters Caralluma Fimbriata, Placebo comparator - Microcrystalline cellulose - Stress, Sleep | Phase 2 / Phase 3 | Completed | RDC Clinical Pty Ltd | 129 | 2022-02-10 | 2023-10-24 |
| Caring Relationships Expression Study Heart Rate Variability Biofeedback, Music Listening Control - Caregiver Burden, Anxiety | Phase 1 / Phase 2 | Completed | Arizona State University | 38 | 2021-12-13 | 2024-02-12 |
| Effect of Renal Denervation on Stress, Hypertension and Anxiety Management Endovascular ultrasound renal denervation (Paradise renal denervation system, ReCor, CA, USA) (RDN) - Hypertension Arterial, Anxiety | Phase 2 | Completed | Hippocration General Hospital | 60 | 2021-10-18 | 2026-07-30 |
Showing 20 of 38. Sign in to see all of them.
Anxiety Disorders (9) · Depression (6) · Alcoholism (2) · Behavior (2) · Dementia (2) · Psychological Well-Being (2) · Alcohol Drinking (1) · Alcohol-Related Disorders (1) · Altruism (1) · Alzheimer Disease (1) · Bulimia (1) · Caregiver Burden (1) · Diabetes Mellitus (1) · Gingival Hemorrhage (1) · Gingivitis (1)
Mental Disorders (14) · Behavior (10) · Behavioral Symptoms (8) · Pathological Conditions, Signs and Symptoms (6) · Nervous System Diseases (4) · Signs and Symptoms (4) · Chemically-Induced Disorders (3) · Substance-Related Disorders (3) · Brain Diseases (2) · Central Nervous System Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Neurocognitive Disorders (2) · Neurologic Manifestations (2) · Pathologic Processes (2) · Personal Satisfaction (2)
Acupuncture, Ear (3) · Auriculotherapy (2) · Hydrocortisone (2) · Probiotics (2) · Yohimbine (2) · Ashwagandha (1) · Atomoxetine Hydrochloride (1) · Cannabidiol (1) · Exercise (1) · Fentanyl (1) · Glycerol (1) · LY2940094 (1) · Massage (1) · Oxytocin (1) · Perioperative Care (1)
Lallemand Health Solutions (3) · University of Sao Paulo (3) · Mclean Hospital (2) · National Center for Complementary and Integrative Health (NCCIH) (2) · RDC Clinical Pty Ltd (2) · Wayne State University (2) · Al-Mustansiriyah University (1) · Arizona State University (1) · Beth Israel Deaconess Medical Center (1) · Cairo University (1) · Collinge and Associates, Inc. (1) · Cook MyoSite (1) · Ethical Naturals, Inc. (1) · Hippocration General Hospital (1) · IRIS Media Inc (1)
United States (19) · Brazil (3) · Canada (3) · Australia (2) · France (2) · Germany (2) · Belgium (1) · Egypt (1) · Greece (1) · Iraq (1) · Romania (1)
Leonice FS Kurebayashi (2) · Maria Julia P Silva (2) · Amanda Rao, PhD (1) · Amy Birney, MPH, MCHES (1) · Batool Alshuwaili, B.D.S (1) · Boushra Dalile, PhD (1) · Brigitte Milpied (1) · Chris Danforth, PhD (1) · David Crowley, M.D (1) · David Crowley, MD (1) · Ellen McGinnis, PhD (1) · Erin Lewis, Ph.D. (1) · Heather Neyedli, Ph.D. (1) · Iris R. Bell, MD, PhD (1) · Jane Doussard-Roosevelt, PhD (1)
PMID 22990158, PMID 25029046, PMID 27678169, PMID 31982647, PMID 32445052, PMID 35984870, PMID 35984871, PMID 36833579, PMID 37583941, PMID 37722484, PMID 37794909, PMID 38758503, PMID 39842791
P50MH119467 (1), R01AA027791 (1), R01AT002477 (1), R01LM012836 (1), R01MH139940 (1), UH3AG052167 (1)