50 completed, 13 unknown, 9 recruiting, 7 not yet recruiting. 89 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 89 | Completed 50, Unknown 13, Recruiting 9, Not yet recruiting 7, Active not recruiting 5, Enrolling by invitation 2, Withdrawn 2, Suspended 1 |
Follow Streptococcal Infections: new trials by email Literature Review of Streptococcal Infections trials Research Report on Streptococcal Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Assessment of the Prevalence of Rheumatic Heart Disease in School Settings in Mayotte and the Acquisition of Ultrasound Sequences Guided by Artificial Intelligence Ultrasound performed bycardiologis for diagnosis of rheumatic heart disease - Rheumatic Heart Diseases, Scabies | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire de la Réunion | 900 | 2027-10-01 | 2026-10-29 |
| Improving Management and Secondary Prevention Through Azithromycin Comparative Trial in Rheumatic Heart Disease in Nigeria)- IMPACT-RHD Nigeria Benzathine Penicillin, Azithromycin (Azithro) - Rheumatic Fever, Valvular Heart Diseases | Not applicable | Not yet recruiting | Ladoke Akintola University of Technology, Ogbomoso, Nigeria | 474 | 2027-01-05 | 2026-06-04 |
| Testing a Registry-Based Strategy (ACT+) to Reduce Loss to Follow-Up in Rheumatic Heart Disease Screening in Uganda The ACT+ Strategy - Rheumatic Heart Disease | Not applicable | Not yet recruiting | Children's Hospital Medical Center, Cincinnati | 16 | 2026-12-01 | 2026-10-13 |
| Artificial Intelligence to Scale Early Rheumatic Heart Disease Detection AI assisted echocardiography - Rheumatic Heart Disease | Not applicable | Not yet recruiting | Children's Hospital Medical Center, Cincinnati | 62 | 2026-11-01 | 2026-10-16 |
| Effects of Paraffin Wax Therapy and Dry Cupping on Pain and Wrist Function in Patients With Rheumatoid Arthritis Paraffin Wax Therapy, Dry cupping - Rheumatic Arthritis | Not applicable | Not yet recruiting | University of Baghdad | 100 | 2026-10-25 | 2026-11-02 |
| Randomized Controlled Trial Of Text Messages To Increase Pneumococcal Vaccination In Adults In Chile. WhatsApp text message reminder for pneumococcal vaccination - Pneumococcal Infections, Immunization Programs | Not applicable | Enrolling by invitation | Pablo Tomás Valenzuela García | 40753 | 2026-10-01 | 2026-10-22 |
| Intervention to Support Partners and Informal Caregivers of Frail RA-patients Caregiver support - Rheumatic Arthritis | Not applicable | Recruiting | Glostrup University Hospital, Copenhagen | 25 | 2026-03-15 | 2026-03-17 |
| Evaluation of Efficacy of Antibacterial Activity of Licorice, Clove, and Chlorohexidine Mouthwashes on Salivary Streptococcus Mutans in a Group of Egyptian Children. Mouth wash - Dental Caries, Streptococcal Infections | Not applicable | Active not recruiting | British University In Egypt | 54 | 2025-10-06 | 2026-09-18 |
| Perspectives on Antibiotics and Tracking Symptoms in Children Garmin Smartwatch - Urinary Tract Infection, Cellulitis | Not applicable | Recruiting | Murdoch Childrens Research Institute | 300 | 2025-09-16 | 2026-10-07 |
| Efficacy and Safety of Resveratrol in Patients With Rheumatoid Arthritis. Resveratrol 1 gm., Methotrexate - Rheumatic Arthritis, Rheumatoid Arthritis (RA) Prevention | Not applicable | Recruiting | Ain Shams University | 118 | 2025-08-01 | 2025-07-28 |
| Effectiveness of Edutainment-Based Interventions in Increasing Knowledge of Rheumatic Fever and Rheumatic Heart Disease Among School-Going Children in Nepal: Study Protocol for Colors to Save Hearts Quasi-Experimental Pretest-Posttest Study education material - Rheumatic Heart Disease | Not applicable | Not yet recruiting | Kathmandu Institute of Child Health | 2400 | 2025-07-28 | 2025-07-15 |
| Effects of Task-Oriented Training and Mulligan Mobilization on Hand Function, Pain and Quality of Life in Patients With Rheumatoid Arthritis Task-oriented trainig, Mulligan mobilization, Conventional treatment - Rheumatic Arthritis | Not applicable | Completed | Kirsehir Ahi Evran Universitesi | 54 | 2025-07-01 | 2025-12-10 |
| Treating Severe Mitral Valve Annular or Valvular Calcification Using Shockwave Balloon SMARTWAVE SmartWave Lithotripsy balloon - Mitral Annulus Calcification, Rheumatic Heart Disease | Not applicable | Recruiting | Prince of Wales Hospital, Shatin, Hong Kong | 10 | 2025-03-08 | 2026-09-16 |
| The Effect of AUDIT and Feedback on Pneumococcal Vaccination Coverage AUDIT and Feedback - Pneumococcal Infections | Not applicable | Unknown | Bert Vaes | 36 | 2025-01-31 | 2024-09-24 |
| School-based Program for the Prevention of Rheumatic Heart Disease in Endemic Regions School nurse program - Rheumatic Heart Disease in Children | Not applicable | Recruiting | Thomas Pilgrim | 6000 | 2024-12-15 | 2026-01-20 |
| Manual Diaphragmatic Release on Ventilatory Functions in Women With Rheumatoid Arthritis Aerobic training, Manual Diaphragm Release - Rheumatic Arthritis, Lung Function | Not applicable | Not yet recruiting | Middle East University | 60 | 2024-12-03 | 2024-12-09 |
| Artificial Intelligence-driven Virtual Standardized Pediatric Patients Trial Virtual standardized patients (VSPs), Case teaching manuals, Case teaching videos - Pneumococcal Pneumonia, Rotavirus Enteritis With Hypovolemic Shock | Not applicable | Recruiting | Southern Medical University, China | 459 | 2024-12-01 | 2024-12-19 |
| Identifying Essential Elements of SAP Supports Case Management Supports - Rheumatic Heart Disease in Children, Heart Disease, Valvular | Not applicable | Completed | Children's Hospital Medical Center, Cincinnati | 335 | 2024-08-21 | 2026-05-28 |
| Group A Streptococcus Saliva Study Saliva collection - Group A Streptococcal Infections | Not applicable | Active not recruiting | The Hospital for Sick Children | 200 | 2024-06-10 | 2026-05-07 |
| Comparison of Wire Assisted Percutaneous Balloon Mitral Valvulotomy With Standard Inoue Balloon Valvulotomy Percutaneous Balloon Mitral Valvulotomy - Rheumatic Heart Disease | Not applicable | Completed | Helse Stavanger HF | 20 | 2024-05-24 | 2024-06-20 |
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Rheumatic Heart Disease (23) · Rheumatic Fever (19) · Pneumococcal Infections (15) · Heart Valve Diseases (6) · Pneumonia, Pneumococcal (6) · Pharyngitis (5) · Impetigo (4) · Arthritis, Rheumatoid (3) · Endocarditis, Subacute Bacterial (3) · Erysipelas (3) · HIV Infections (3) · Otitis Media (3) · Whooping Cough (3) · Atrial Fibrillation (2)
Bacterial Infections (89) · Bacterial Infections and Mycoses (89) · Gram-Positive Bacterial Infections (89) · Infections (88) · Cardiovascular Diseases (27) · Heart Diseases (27) · Skin and Connective Tissue Diseases (27) · Connective Tissue Diseases (21) · Rheumatic Fever (21) · Arthritis (19) · Joint Diseases (19) · Musculoskeletal Diseases (19) · Respiratory Tract Diseases (19) · Respiratory Tract Infections (18)
Pneumococcal Vaccines (5) · Heptavalent Pneumococcal Conjugate Vaccine (4) · Amoxicillin (2) · Echocardiography (2) · Probiotics (2) · 13-valent pneumococcal vaccine (1) · 23-valent pneumococcal capsular polysaccharide vaccine (1) · Azithromycin (1) · Blood Specimen Collection (1) · Case Managers (1) · Cognitive Behavioral Therapy (1) · Exercise (1) · Heart Rate (1) · Hepatitis B Vaccines (1) · Immunologic Tests (1)
Children's Hospital Medical Center, Cincinnati (7) · Assistance Publique - Hôpitaux de Paris (4) · China Medical University Hospital (2) · Ellume Pty Ltd (2) · Insel Gruppe AG, University Hospital Bern (2) · Molde University College (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · Sun Yat-sen University (2) · Thomas Pilgrim (2) · University Hospital, Bordeaux (2) · Aga Khan University (1) · Ain Shams University (1) · Auburn University (1) · Aysima Barlak (1) · Bert Vaes (1)
United States (14) · France (9) · Uganda (7) · Nepal (5) · Canada (4) · China (4) · Egypt (4) · Turkey (Türkiye) (4) · Denmark (3) · Norway (3) · Switzerland (3) · Australia (2) · Brazil (2) · Ethiopia (2) · Russia (2)
Andrea Z Beaton (3) · Andrea Beaton (2) · Jan Helgerud, PhD (2) · Jing-song Ou, MD,PhD (2) · Abdul M Kazi, MBBS,MPH (1) · Adeseye A Akintunde (1) · Al Shymaa Farouk, Lecturer of Internal Medicine (1) · Andrew Steer, PhD (1) · Anne-Sylvie Ramelet, PhD (1) · Ardian Rizal, MD, FIHA (1) · Ari Robicsek, MD (1) · Aygin Bayraktar-Ekincioglu (1) · Barnaby H Montgomery (1) · Bente Esbensen, Professor (1)
PMID 11723015, PMID 16061117, PMID 16844920, PMID 17938165, PMID 18050377, PMID 19663708, PMID 22107759, PMID 22685225, PMID 22693229, PMID 22796581, PMID 24939642, PMID 25910923, PMID 27153752, PMID 28716081, PMID 29194364, PMID 29383550, PMID 29611086, PMID 30418528, PMID 30720339, PMID 30777645, PMID 31148544, PMID 31735650, PMID 31883358, PMID 32192948, PMID 32730400, PMID 32813276, PMID 32975529, PMID 33471029, PMID 33728462, PMID 33820851, PMID 33922273, PMID 34673536, PMID 34758017, PMID 35438424, PMID 36285530, PMID 36369238, PMID 36675041, PMID 36706172, PMID 36797077, PMID 37108584, PMID 38697766, PMID 38955352, PMID 39061843, PMID 39424380, PMID 39460318, PMID 39665614, PMID 40065836, PMID 40155108, PMID 40423396, PMID 40716613
R01AI108479 (1), R21AI166120 (1), U19AI053217 (1), U19AI090023 (1)