215 completed, 32 unknown, 7 not yet recruiting, 6 active not recruiting. 90 Phase 3, 54 Phase 4, 31 Phase 2, 23 Not applicable, 22 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Assessment of the Acceptability of, and Factors Associated With, Recommended Vaccinations During Pregnancy in Maternity Units in the Ile-de-France Region Vaccination Coverage Among Pregnant Women | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 1605 | 2026-11-01 | 2026-10-20 | |
| A Clinical Study on Immunogenicity Persistence of Adsorbed 5-component Acellular Pertussis, Diphtheria and Tetanus Combined Vaccine Previously received the Tdcp vaccine at age 18 and older, Previously received the Tdcp vaccine at age 12-17, Previously received the Tdcp vaccine at age 6-11 - Diphtheria, Tetanus | Not yet recruiting | CanSino Biologics Inc. | 160 | 2026-10-15 | 2026-08-04 | |
| Study of BK1803 in Healthy Infants BK1803, GOBIK Aqueous Suspension Syringes, Bimmugen® Injection - Pertussis, Diphtheria | Phase 3 | Not yet recruiting | Tanabe Pharma Corporation | 344 | 2026-10-01 | 2026-08-28 |
| Maternal Immunization With Tetanus Toxoid, Reduced Diphtheria Toxoid, Reduced-dose (2 µg) Recombinant Pertussis Vaccine (TdaP2gen) and Its Effect on the Immune Response in Thai Infants up to 15-18 Months Old Maternal TdaP2gen vaccine, Infant Acellular Pertussis-containing Vaccine, Infant Whole-cell Pertussis-containing Vaccine - Pertussis, Diphtheria | Phase 4 | Not yet recruiting | Chiang Mai University | 320 | 2026-05-26 | 2026-06-02 |
| A Phase I Clinical Trial of Absorbed Acellular Pertussis (Two-Component) Diphtheria-Tetanus Combined Vaccine (For Adults and Adolescents) Tdap vaccine - Pertussis (Whooping Cough), Diphtheria | Phase 1 | Not yet recruiting | Changchun BCHT Biotechnology Co. | 96 | 2026-04-20 | 2026-03-25 |
| Phase I/II Clinical Trial of Diphtheria-Tetanus-Pertussis (Reduced Dose) Vaccine low-dose Tetanus, Diphtheria and Acellular Component Pertussis Vaccine Adsorbed (Reduced Antigens Content), high-dose Tetanus, Diphtheria and Acellular Component Pertussis Vaccine Adsorbed (Reduced Antigens Content), Tetanus, Diphtheria and Acellular Pertussis Vaccine - Tetanus, Diphtheria and Acellular Pertussis Vaccination, Tetanus | Phase 1 / Phase 2 | Not yet recruiting | Institute of Medical Biology, Chinese Academy of Medical Sciences | 660 | 2026-03-12 | 2026-02-18 |
| Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective Dengue, Chikungunya | Recruiting | Institut Pasteur du Cambodge | 10000 | 2025-12-18 | 2026-01-22 | |
| Establishing a Controlled Human Infection Model of Pertactin-deficient Bordetella Pertussis Biological: Bordetella pertussis J820 - Pertussis (Whooping Cough) | Phase 1 | Recruiting | Dalhousie University | 60 | 2025-11-24 | 2025-12-04 |
| A Phase II/III Study to Evaluate the Immunogenicity, Safety and Lot-to-lot Consistency of LBVD, a Fully Liquid Hexavalent Diphtheria-tetanus-whole Cell Pertussis-hepatitis B-poliovirus-Haemophilus Influenzae Type b Conjugate (DTwP-HepB-IPV-Hib) Vaccine, in Healthy Infants as Primary Series LBVD, Pentavalent vaccine and Inactivated Polio vaccine - Diphtheria, Tetanus | Phase 2 / Phase 3 | Active not recruiting | LG Chem | 1186 | 2025-05-30 | 2026-09-03 |
| Study of Concomitant Administration of the sIPV and DTaP or MMR sIPV, DTaP, bOPV 1,3 - Polio, Diphteria, Tetanus and Pertussis | Phase 4 | Not yet recruiting | Institute of Medical Biology, Chinese Academy of Medical Sciences | 2640 | 2025-05-15 | 2025-04-17 |
| 10-year Follow-up After a Single Dose Acellular Pertussis Vaccination Pertagen® vaccine, Adacel® vaccine - Pertussis | Phase 4 | Completed | Mahidol University | 90 | 2025-05-13 | 2026-10-08 |
| A Clinical Trials of Adsorbed Cell-free DPT Vaccine (Five-component) Tetanus, Reduced Diphtheria and Acellular Pertussis (Five Components) Combined Vaccine, Adsorbed (Tdcp)), 23-valent Pneumococcal Polysaccharide Vaccine (PPV23), Tdcp - Diphtheria, Tetanus | Phase 2 / Phase 3 | Completed | CanSino Biologics Inc. | 1820 | 2024-12-20 | 2026-08-26 |
| Study Evaluating the Safety of a Recombinant Acellular Pertussis Vaccine in Pregnant Women Pertussis Vaccines, Pertussis (Whooping Cough) | Active not recruiting | BioNet-Asia Co., Ltd. | 2700 | 2024-12-12 | 2025-10-03 | |
| A Phase 4, Randomised Vaccination Study in Healthy Adults to Investigate the Effects of Acellular Pertussis Vaccine on Colonisation With Bordetella Pertussis Using Controlled Human Infection Tdap-IPV, Td-IPV - Pertussis Infection, Pertussis Vaccines | Phase 4 | Active not recruiting | Dimitri Diavatopoulos | 99 | 2024-10-16 | 2026-05-07 |
| CARE-ID: Dynamics of Respiratory Infections in Children and Transmission in Households and Schools Daily Influenza, RSV or SARS-CoV-2 PCR testing for 14 days - SARS CoV 2 Infection, RSV Infection | Active not recruiting | The Hospital for Sick Children | 500 | 2024-10-10 | 2026-05-01 | |
| Study to Evaluate the Immunogenicity of LR20062 Compared to Control When Administered Intramuscularly in Healthy Infants At 2, 4, 6 Months of Age LR20062, DTaP-HepB-IPV-Hib vaccine - Diphtheria, Tetanus | Phase 2 | Unknown | LG Chem | 336 | 2024-10-02 | 2024-10-01 |
| Safety and Immunogenicity of DTaP-IPV/Hib Pentavalent Vaccine in Chinese 2-month-old Infants Different immunization regiments with DTaP-IPV/Hib Pentavalent Vaccine - Pertussis, Diphtheria | Not applicable | Unknown | Jiangsu Province Centers for Disease Control and Prevention | 785 | 2024-09-05 | 2024-09-20 |
| LIAISON NES Influenza (FLU) A/B, Respiratory Syncytial Virus (RSV), & Coronavirus Disease 2019 (COVID-19) in Symptomatic Patients in Australia LIAISON NES FLU A/B, RSV, & COVID-19, LIAISON PLEX Respiratory Flex Assay - Influenza A, Influenza Type B | Not applicable | Unknown | DiaSorin Molecular LLC | 1000 | 2024-05-06 | 2024-04-30 |
| Safety of Tetanus, Diphtheria, Acellular Pertussis With 5 Acellular Pertussis Components (Tdap5) Vaccination During Pregnancy Not applicable / database analysis - Pertussis (Whooping Cough) | Active not recruiting | Sanofi | 365000 | 2024-01-02 | 2026-04-06 | |
| Phase I Clinical Trial of Diphtheria-Tetanus-acellular Pertussis Component Combined Vaccine DTacP (one-dose booster), DTacP (three-dose primary vaccination), DT (one-dose booster) - Diphtheria, Tetanus | Phase 1 | Recruiting | Institute of Medical Biology, Chinese Academy of Medical Sciences | 460 | 2023-12-23 | 2024-01-03 |
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Tetanus (165) · Diphtheria (159) · Poliomyelitis (80) · Hepatitis B (72) · Haemophilus Infections (71) · Influenza, Human (16) · Measles (9) · Meningococcal Infections (9) · Infections (8) · Meningitis (8) · Bacterial Infections (7) · Virus Diseases (7) · Communicable Diseases (5) · Meningitis, Meningococcal (4)
Bacterial Infections and Mycoses (269) · Gram-Negative Bacterial Infections (268) · Respiratory Tract Diseases (268) · Bordetella Infections (267) · Respiratory Tract Infections (267) · Bacterial Infections (262) · Infections (261) · Gram-Positive Bacterial Infections (172) · Clostridium Infections (165) · Actinomycetales Infections (160) · Corynebacterium Infections (159) · Virus Diseases (121) · RNA Virus Infections (103) · Nervous System Diseases (90) · Neuroinflammatory Diseases (89)
Tetanus Toxoid (41) · adacel (32) · Boostrix (19) · Diphtheria-Tetanus-acellular Pertussis Vaccines (18) · Pentavac (13) · diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae b conjugate-hepatitis B vaccine (11) · Blood Specimen Collection (10) · DTaP-IPV-HB-PRP-T vaccine (10) · pentacel (10) · Data Collection (8) · Heptavalent Pneumococcal Conjugate Vaccine (7) · Hiberix (7) · Poliovirus Vaccine, Inactivated (7) · Vaccines, Combined (7) · Diphtheria-Tetanus Vaccine (6)
Sanofi Pasteur, a Sanofi Company (58) · GlaxoSmithKline (39) · Sanofi (20) · National Institute of Allergy and Infectious Diseases (NIAID) (10) · LG Chem (7) · Merck Sharp & Dohme LLC (7) · Mahidol University (5) · St George's, University of London (5) · CanSino Biologics Inc. (4) · BioNet-Asia Co., Ltd. (3) · Crucell Holland BV (3) · Dalhousie University (3) · Emory University (3) · ILiAD Biotechnologies (3) · Institut Pasteur (3)
United States (52) · Canada (18) · China (17) · Thailand (17) · South Korea (13) · Philippines (12) · United Kingdom (12) · France (9) · Belgium (8) · Germany (8) · India (8) · Japan (7) · Mexico (7) · Russia (6) · South Africa (6)
Raman Rao, MD (3) · Elizabeth Coates, PhD (2) · Elke Leuridan, MD, PhD (2) · Eva Netterlid (2) · Geeta Swamy, MD (2) · Lingwei Wang (2) · Maria RZ Capeding, MD (2) · Marina Rusanova (2)
PMID 20657177, PMID 29172945, PMID 31945015, PMID 37285482, PMID 14670310, PMID 16511379, PMID 17090650, PMID 17938165, PMID 19095033, PMID 19117896, PMID 19663708, PMID 19952980, PMID 20189491, PMID 20439595, PMID 20448468, PMID 20616762, PMID 20955461, PMID 21134450, PMID 21219984, PMID 21289531, PMID 21334243, PMID 21372751, PMID 21807056, PMID 21817954, PMID 22001281, PMID 22115634, PMID 22157567, PMID 22238169, PMID 22273029, PMID 22349525, PMID 22475857, PMID 22531237, PMID 22691430, PMID 22693229, PMID 23077849, PMID 23241989, PMID 23783081, PMID 23966556, PMID 24176498, PMID 24261996, PMID 24346596, PMID 24421886, PMID 24461900, PMID 24726248, PMID 24793938, PMID 24794369, PMID 24835247, PMID 25008903, PMID 25156560, PMID 25230939
2014 (3), 2015 (2), 2008 (1), 2016 (1), 2018 (1), 2023 (1), P01TP000300 (1), R21AI141822 (1), R34AI148056 (1), U01IP001110 (1)