104 completed, 11 recruiting, 7 unknown, 5 terminated. 34 Phase 2, 33 Phase 3, 28 Phase 4, 17 Phase 1, 16 Not applicable.
Follow Pneumococcal Vaccines: new trials by email Literature Review of Pneumococcal Vaccines trials Research Report on Pneumococcal Vaccines
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Induction of Cross-protective Antibodies for Serogroup 33 by Pneumococcal Conjugate Vaccines Pneumococcal Vaccine - Vaccine, Pneumococcal Disease | Phase 4 | Recruiting | University of Alabama at Birmingham | 70 | 2026-07-01 | 2026-08-21 |
| Influence of Methotrexate Discontinuation on Immunogenicity After PCV-20 Vaccine in Patients ARDs Pneumococcal Vaccine - Autoimmune Rheumatic Diseases | Phase 4 | Recruiting | University of Sao Paulo General Hospital | 192 | 2026-06-22 | 2026-07-20 |
| Structured Review: To Optimise Management and Prevent Harm in COPD Sputum sample, Venepuncture, Lung function test - COPD | Not applicable | Recruiting | Northumbria Healthcare NHS Foundation Trust | 96 | 2026-03-11 | 2026-04-23 |
| Opportunistic Pneumococcal Immunisation Trial in MALnutrition Pneumococcal conjugate vaccine, Typhoid conjugate vaccine - Severe Acute Malnutrition in Childhood, Pneumococcal Disease | Phase 4 | Recruiting | Nick Fancourt | 214 | 2026-01-16 | 2026-10-08 |
| Safety and Immunogenicity of PCV20 in Pediatric Patients With Autoimmune Rheumatic Diseases Pneumococcal Vaccine - Autoimmune Rheumatologic Disease | Phase 4 | Recruiting | University of Sao Paulo General Hospital | 114 | 2026-01-16 | 2026-03-04 |
| Clinical Trial of PCV24 in Adults Aged ≥18 Years Sinovac Low-dosage PCV24, Sinovac Middle-dosage PCV24, Sinovac High-dosage PCV24 - Pneumococcal Infectious Disease | Phase 1 / Phase 2 | Completed | Sinovac Life Sciences Co., Ltd. | 385 | 2025-06-18 | 2026-04-21 |
| A Study on the Immune Response and Safety of the Second Dose of an Investigational Chickenpox Vaccine When Given to Healthy Children 3 Months After a First Dose at 12 to 15 Months of Age Investigational varicella vaccine, Marketed varicella vaccine, MMR vaccine - Chickenpox | Phase 3 | Recruiting | GlaxoSmithKline | 600 | 2025-05-15 | 2026-05-29 |
| A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine and a Marketed Measles, Mumps and Rubella Vaccine When Administered as Intramuscular Injection to Healthy Children 12 to 15 Months of Age Candidate varicella vaccine, Marketed varicella vaccine, MMR vaccine - Chickenpox | Phase 3 | Recruiting | GlaxoSmithKline | 911 | 2025-04-17 | 2026-05-29 |
| A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age Investigational varicella vaccine_Lot 1, Investigational varicella vaccine_Lot 2, Investigational varicella vaccine_Lot 3 - Chickenpox | Phase 3 | Recruiting | GlaxoSmithKline | 1840 | 2025-01-10 | 2026-05-29 |
| A Study on the Safety of an Investigational Chickenpox Vaccine, When Given to Healthy Children, 12 to 15 Months of Age Investigational varicella vaccine, Marketed varicella vaccine, Measles, mumps, and rubella vaccine - Chickenpox | Phase 3 | Recruiting | GlaxoSmithKline | 750 | 2024-11-26 | 2026-05-29 |
| Clinical Trial of PCV24 in Adults Sinovac PCV24 formulation 1, Sinovac PCV24 formulation 2, Pneumovax® - Pneumococcal Infectious Disease | Phase 1 | Completed | Sinovac Life Sciences Co., Ltd. | 170 | 2024-06-21 | 2025-04-16 |
| Co-administration Study of an Investigational Live-Attenuated Respiratory Syncytial Virus Vaccine in Infants and Toddlers RSVt vaccine, Diphtheria, tetanus, pertussis, poliomyelitis , Haemophilus influenzae type b, and hepatitis B vaccine, Diphtheria, tetanus, pertussis, Haemophilus influenzae type b and poliomyelitis vaccine - RSV Immunization | Phase 3 | Terminated | Sanofi Pasteur, a Sanofi Company | 2226 | 2024-05-13 | 2026-10-05 |
| Anti-pneumococcal Vaccine Strategy in Patients With Chronic Lymphocytic Leukemia Pneumococcal 20-valent Conjugate Vaccine, Pneumococcal Polyvalent Vaccine - Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma | Phase 2 | Recruiting | Seema Bhat | 80 | 2023-09-29 | 2026-01-07 |
| Fine Needle aSpiration of Lymph nodEs to Study vAccine-induced Immunity Pneumococcal Vaccine - Vaccine-Preventable Diseases | Not applicable | Unknown | Leiden University Medical Center | 5 | 2023-04-15 | 2024-01-11 |
| Pneumococcal Vaccination in Patients with Anti-TNF Alpha Therapy Pneumococcal vaccine - Pneumococcal Vaccine | Completed | Hôpital NOVO | 106 | 2023-04-03 | 2024-09-19 | |
| Evaluating the Effectiveness of a Pneumococcal Immunisation Campaign in a Camp for Internally Displaced People Pneumococcal conjugate vaccine - Pneumococcal Infections | Phase 4 | Active not recruiting | London School of Hygiene and Tropical Medicine | 2882 | 2022-11-27 | 2025-06-04 |
| Fourth Dose of mRNA COVID-19 Vaccine in Residents of LTCFs mRNA- COVID-19, Prevnar13 - SARS-CoV2 Infection, Coronavirus Infection | Phase 4 | Unknown | Mark Loeb | 414 | 2022-08-01 | 2022-06-30 |
| Pneumococcal Pneumonia Vaccine Series (PCV20 and PPSV23) in Patients With Chronic Lymphocytic Leukemia Associated Immunodeficiency, PROTECT CLL Trial Pneumococcal 20-valent Conjugate Vaccine, Pneumococcal Polyvalent Vaccine - Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma | Phase 2 | Recruiting | University of Utah | 61 | 2022-01-31 | 2026-04-09 |
| Safety Study to Evaluate Immune Response of Vaccines in Participants With Relapsing Forms of Multiple Sclerosis Who Receive Ozanimod Compared to Non-Pegylated Interferon (IFN)-β or No Disease Modifying Therapy Tetanus, diphtheria, and acellular pertussis vaccine, Pneumococcal polysaccharide vaccine, Seasonal influenza vaccine - Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting | Phase 3 | Completed | Celgene | 63 | 2021-11-11 | 2025-02-11 |
| PREVENTING PNEUMOcoccal Disease Through Vaccination (Study 2) PPV23, PCV13, Saline for injection - Streptococcus Pneumonia | Phase 4 | Unknown | Liverpool School of Tropical Medicine | 516 | 2021-07-28 | 2023-01-05 |
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Pneumococcal Infections (32) · Pneumonia (14) · HIV Infections (9) · Leukemia, Lymphocytic, Chronic, B-Cell (7) · Pneumonia, Pneumococcal (7) · Multiple Myeloma (6) · Streptococcal Infections (6) · Chickenpox (5) · Meningitis (5) · Meningococcal Infections (5) · Arthritis, Rheumatoid (4) · Asthma (4) · Hepatitis B (4) · Pulmonary Disease, Chronic Obstructive (4) · Tetanus (4)
GlaxoSmithKline (15) · Sanofi Pasteur, a Sanofi Company (8) · Merck Sharp & Dohme LLC (7) · National Institute of Allergy and Infectious Diseases (NIAID) (6) · Assistance Publique - Hôpitaux de Paris (3) · Mayo Clinic (3) · Novartis (3) · H. Lee Moffitt Cancer Center and Research Institute (2) · Helsinki University Central Hospital (2) · Institut National de la Santé Et de la Recherche Médicale, France (2) · National Cancer Institute (NCI) (2) · Novartis Vaccines (2) · Pfizer (2) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (2) · Sinovac Life Sciences Co., Ltd. (2)
United States (52) · France (9) · Germany (9) · Poland (7) · China (5) · Finland (5) · Puerto Rico (5) · Belgium (4) · Canada (4) · Mexico (4) · Spain (4) · United Kingdom (4) · Colombia (3) · Denmark (3) · Estonia (3)
Aaron P. Rapoport, MD (2) · Amanda J Leach, PhD (1) · Amar Safdar, MD (1) · Anatoly Uss, MD/PhD (1) · Andreas M Petersen, MD (1) · Anthony Scott, MD, PhD (1) · Antonello Punturieri, MD (1) · Anu Kantele, MD PhD (1) · Avni Y Joshi (1) · Benjamin Rossi, MD (1)
PMID 40396505, PMID 24290843, PMID 11115712, PMID 1347058, PMID 17258358, PMID 17938165, PMID 18470901, PMID 19150378, PMID 19556517, PMID 19663708, PMID 19776196, PMID 19814624, PMID 20088694, PMID 20219110, PMID 20299956, PMID 20504165, PMID 20795819, PMID 20864577, PMID 20887830, PMID 20980796, PMID 21030558, PMID 21173013, PMID 21645573, PMID 21860256, PMID 22094635, PMID 22123890, PMID 22241792, PMID 22318278, PMID 22652582, PMID 22693229, PMID 22854665, PMID 22863660, PMID 23131206, PMID 23451070, PMID 23535358, PMID 23744509, PMID 23954381, PMID 24448345, PMID 25579777, PMID 2572650, PMID 26143615, PMID 26275480, PMID 26529076, PMID 27145999, PMID 27939054, PMID 28580433, PMID 28702291, PMID 28784280, PMID 29028802, PMID 29116597
2009 (2), 2005 (1), 2014 (1), 2016 (1), 2018 (1), N01CM00070 (1), N01CM62207 (1), P01CA095426 (1), P30CA006973 (1), P30CA016058 (1), P50CA140158 (1), R01AG045973 (1), R01AI108479 (1), R01AI118422 (1), U10HL074424 (1)