5 recruiting, 1 active not recruiting, 1 completed, 1 enrolling by invitation. 2 Not applicable, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Recruiting 2 |
| Phase 3 | 2 | Recruiting 2 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Analgesia for Cardiac Elective Surgery in Children Methadone based ERAS, Non-methadone based group - Pediatric Cardiac Surgery | Phase 3 | Recruiting | Senthil Sadhasivam | 500 | 2025-12-17 | 2026-08-07 |
| Evaluation of Analgesia for Spine Fusion Elective Surgery in Children Methadone based ERAS, Non-methadone based group - Idiopathic Scoliosis | Phase 3 | Recruiting | Senthil Sadhasivam | 500 | 2025-10-30 | 2026-10-07 |
| Multimodal Fetal and Placental Imaging and Biomarkers of Clinical Outcomes in Opioid Use Disorder Buprenorphine or Methadone Treatment, Fetal and Placental MRI, Child Developmental Assessment - Opioid Use Disorder, Substance-Related Disorders | Enrolling by invitation | Senthil Sadhasivam | 250 | 2024-02-13 | 2026-07-14 | |
| Personalized Perioperative Analgesia Platform (PPAP) for Cesarean Section Preoperative Genotyping - Cesarean Section Complications, Opioid Use | Not applicable | Recruiting | Senthil Sadhasivam | 700 | 2022-12-05 | 2026-09-10 |
| Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB) Preoperative Genotyping - PPAP, Spine Fusion | Not applicable | Recruiting | Senthil Sadhasivam | 300 | 2022-09-20 | 2026-09-10 |
| Personalizing Perioperative Analgesia in Children Postoperative Pain | Active not recruiting | Senthil Sadhasivam | 1200 | 2022-02-07 | 2026-09-17 | |
| Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes Subutex / Buprenorphine, Fetal & Neonatal MRI, DNA/Genetic/Pharmacokenetic Blood Draws - Opioid-use Disorder, Opioid Use, Unspecified | Recruiting | Senthil Sadhasivam | 600 | 2018-09-15 | 2025-12-18 | |
| PG and PK of Oxycodone to Personalize Post-op Pain Management Following Surgery in Children Oxycodone - Postoperative Pain, Opioid Dependence | Completed | Senthil Sadhasivam | 129 | 2018-04-01 | 2025-08-11 |
Opioid-Related Disorders (3) · Pain, Postoperative (2) · Narcotic-Related Disorders (1) · Pain (1) · Respiratory Insufficiency (1) · Substance-Related Disorders (1)
Buprenorphine (2) · Blood Specimen Collection (1) · Oxycodone (1) · Standard of Care (1) · Surveys and Questionnaires (1)
United States (8)
Senthilkumar Sadhasivam, MD, MPH (4) · Senthilkumar Sadhasivam, MD (2) · Alisha Maslanka, BS (1)
PMID 22529273, PMID 22941849, PMID 24122716, PMID 24533707, PMID 25521773, PMID 25558980, PMID 26810133, PMID 32090339, PMID 33481403, PMID 34029273, PMID 34100292, PMID 36946298
R01HD089458 (2), U01HD116257 (2), U01TR003719 (2), R01DA059321 (1), R01HD096800 (1)