384 completed, 96 recruiting, 69 unknown, 47 not yet recruiting. 352 Not applicable, 111 Phase 2, 79 Phase 1, 32 Phase 3, 25 Phase 4.
Follow Spinal Cord Injury: new trials by email Literature Review of Spinal Cord Injury trials Research Report on Spinal Cord Injury
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of iPSC-Derived Motor Neuron Cells (XS228) in Subacute Spinal Cord Injury: A Phase II Randomized Controlled Trial Allogeneic Human Induced Pluripotent Stem Cell (iPSC)-Derived Motor Neuron Progenitor Cells, Placebo - Spinal Cord Injury, Safety | Phase 2 | Not yet recruiting | XellSmart Bio-Pharmaceutical (Suzhou) Co., Ltd. | 60 | 2028-05-25 | 2025-11-25 |
| Testosterone Therapy With or Without Finasteride After Spinal Cord Injury: TRT-SCI Trial testosterone cypionate, finasteride, placebo injection - Spinal Cord Injury, Spinal Cord Injuries | Phase 2 / Phase 3 | Not yet recruiting | VA Office of Research and Development | 300 | 2027-10-01 | 2026-08-04 |
| Empowerment Program to Reduce Treatment of Asymptomatic Bacteriuria in Veterans With Spinal Cord Injury Empowerment Program - Spinal Cord Injury, Spinal Cord Disease | Not applicable | Not yet recruiting | VA Office of Research and Development | 30 | 2027-08-02 | 2026-08-19 |
| Xo-Motion R Exoskeleton in SCI-Adoption Study XoMotionR- assisted locomotor training - Spinal Cord Injury | Not applicable | Not yet recruiting | University of Alberta | 16 | 2027-03-01 | 2026-09-16 |
| Assessment of Safety and Effectiveness of Spatial StimelMD (SSMD) in Subjects With Upper Limb Neuromotor Impairments SSMD, Functional Electrical Stimulation (FES) - Stroke, TBI | Not applicable | Not yet recruiting | Motion Informatics LTD | 120 | 2026-12-30 | 2026-02-11 |
| The Effects of Eccentric Compared to Standard Strength Training in Primary Spinal Cord Injury Rehabilitation Eccentric (KREHA) training, Standard clinical routine strength (STAN) training - Spinal Cord Injury | Not applicable | Not yet recruiting | Swiss Paraplegic Research, Nottwil | 20 | 2026-12-01 | 2026-09-28 |
| Olfactory Cell Transplantation and Intensive Rehabilitation to Repair Chronic Spinal Cord Injury Olfactory Ensheathing Cell, biological intervention, rehabilitation - Spinal Cord Injury, Neurological Conditions | Phase 1 | Not yet recruiting | Dr Brent McMonagle | 30 | 2026-12-01 | 2026-10-21 |
| SERENITY Study of Chronic Pain Interference in Adults Chronic Low Back Pain, Spinal Cord Injury | Not yet recruiting | University of Minnesota | 400 | 2026-11-01 | 2026-10-13 | |
| Exoskeletal-assisted Walking Combined With Transcutaneous Spinal Cord Stimulation: Effect on Imaging and Serum Biomarkers of Skeletal Muscle Mass and Bone Strength. Exoskeleton-Assisted Walking (EAW), Sham Transcutaneous Spinal Cord Stimulation (tSCS), Active Transcutaneous Spinal Cord Stimulation (tSCS) - Spinal Cord Injury | Not applicable | Not yet recruiting | VA Office of Research and Development | 24 | 2026-11-01 | 2026-07-22 |
| Transcutaneous Spinal Cord Stimulation for Neurorehabilitation After Spinal Cord Injury ExaStim® Transcutaneous Spinal Cord Stimulation, Conventional Rehabilitation - Spinal Cord Injury | Not applicable | Not yet recruiting | Ernesto Losavio | 20 | 2026-11-01 | 2026-10-26 |
| Comparison Between Objective Biomechanical Cost and Perceived Physical Demand in Manual Wheelchair Users During Propulsion Tasks Instrumented Manual Wheelchair Propulsion Tasks (Motion Analysis and Instrumented Handrims), Concurrent Cognitive Task (Auditory-Verbal 2-back) - Manual Wheelchair Use, Spinal Cord Injury | Not applicable | Recruiting | Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française | 15 | 2026-10-19 | 2026-10-27 |
| Patterns of Rehabilitation After Spinal Cord Injury Spinal Cord Injury | Recruiting | Gaziler Physical Medicine and Rehabilitation Education and Research Hospital | 103 | 2026-10-06 | 2026-10-08 | |
| iBCI Optimization for Veterans With Paralysis Mobile neural decoding platform (mobile iBCI) - Spinal Cord Injury, Amyotrophic Lateral Sclerosis | Not applicable | Not yet recruiting | VA Office of Research and Development | 2 | 2026-10-02 | 2026-07-27 |
| Cardiovascular Autonomic Function After Resistance Training Upper-Limb Resistance Training - Spinal Cord Injury | Not applicable | Not yet recruiting | Pusan National University Yangsan Hospital | 20 | 2026-10-01 | 2026-09-03 |
| Transcutaneous Auricular Vagus Nerve Stimulation as a Treatment for Neuropathic Pain Following Spinal Cord Injury Active Transcutaneous Auricular Vagus Nerve Stimulation, Sham Transcutaneous Auricular Vagus Nerve Stimulation - Spinal Cord Injury, Neuropathic Pain | Not applicable | Not yet recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 32 | 2026-10-01 | 2026-05-15 |
| Digital Patient Engagement in Technology-Supported Neurorehabilitation Stroke, Parkinson Disease (PD) | Not yet recruiting | Catholic University, Italy | 129 | 2026-10-01 | 2026-09-15 | |
| Time Comparison of Interventions on Bowel Programs in Spinal Cord Injury Suppository, Enemeez, Peristeen - Spinal Cord Injury, Neurogenic Bowel | Not applicable | Recruiting | Casa Colina Hospital and Centers for Healthcare | 30 | 2026-10-01 | 2026-10-09 |
| Spinal Stimulation With Gait Training to Improve Lower Limbs Motor Recovery in Spinal Cord Injury Protocol 1: Gait training combined with a sham stimulation, Protocol 2: Gait training combined with an effective tSCS - Spinal Cord Injury, Spinal Cord Injury Subacute | Not applicable | Not yet recruiting | Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal | 40 | 2026-10-01 | 2026-08-03 |
| Robot-Assisted Intensive Physiotherapy in Individuals With Spinal Cord Injury Robot-Assisted Physiotherapy, Conventional Physiotherapy - Spinal Cord Injury | Not applicable | Recruiting | Nuh Naci Yazgan University | 52 | 2026-10-01 | 2026-10-02 |
| Personal Exoskeleton or Manual Wheelchair: a Comparison of Performance and Satisfaction in Activities of Daily Living Among People With Spinal Cord Injuries, Using the SCED Methodology. Carrying out tasks using the EVE exoskeleton and a manual wheelchair. - Paraplegia, Spinal Cord Injury | Not applicable | Not yet recruiting | Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de Kerpape | 5 | 2026-10-01 | 2026-09-18 |
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Spinal Cord Injuries (688) · Quadriplegia (63) · Stroke (44) · Paraplegia (40) · Motor Activity (27) · Multiple Sclerosis (26) · Paralysis (24) · Muscle Spasticity (23) · Neuralgia (23) · Chronic Pain (18) · Brain Injuries, Traumatic (15) · Pressure Ulcer (15) · Spinal Cord Diseases (15) · Hypotension, Orthostatic (14) · Nervous System Diseases (13)
Trauma, Nervous System (684) · Central Nervous System Diseases (682) · Wounds and Injuries (677) · Nervous System Diseases (675) · Spinal Cord Diseases (673) · Pathological Conditions, Signs and Symptoms (209) · Signs and Symptoms (200) · Neurologic Manifestations (165) · Cardiovascular Diseases (71) · Vascular Diseases (71) · Brain Diseases (66) · Paralysis (66) · Musculoskeletal Diseases (53) · Cerebrovascular Disorders (49) · Neuromuscular Diseases (49)
Exercise (10) · Transcranial Direct Current Stimulation (10) · Botulinum Toxins, Type A (6) · Brain-Computer Interfaces (5) · Electric Stimulation (5) · Midodrine (5) · Rehabilitation (5) · 4-Aminopyridine (4) · Resistance Training (4) · Saline Solution (4) · Transcranial Magnetic Stimulation (4) · Vitamin D (4) · salicylhydroxamic acid (4) · Baclofen (3) · Cholecalciferol (3)
VA Office of Research and Development (45) · US Department of Veterans Affairs (35) · James J. Peters Veterans Affairs Medical Center (26) · Swiss Paraplegic Research, Nottwil (21) · University of Miami (18) · Shirley Ryan AbilityLab (17) · Kessler Foundation (13) · University of British Columbia (11) · University of Zurich (11) · National Taiwan University Hospital (9) · University of Washington (8) · Spaulding Rehabilitation Hospital (7) · Craig Hospital (6) · University of Manitoba (6) · University of Michigan (6)
United States (347) · Canada (59) · Switzerland (48) · China (24) · France (21) · United Kingdom (21) · Turkey (Türkiye) (19) · Spain (18) · Brazil (17) · Taiwan (12) · Australia (10) · Italy (10) · South Korea (9) · Denmark (8) · Netherlands (7)
Mark S Nash, PhD (10) · William Bauman, MD (9) · Nancy Rocheleau, Program Analyst (6) · John Fryer, Ph.D. Asst. Director (5) · Jill M Wecht, Ed.D. (4) · Jill Wecht, EdD (4) · Kenneth J Hunt, BSc, PhD, DSc (4) · Thomas J Schnitzer, MD, PhD (4) · Trevor A. Dyson-Hudson, M.D. (4) · Ann M Spungen, EdD (3) · Ashraf Gorgey, PhD PT (3) · Cristiane F Villarreal, PhD (3) · Edelle C Field-Fote, PT, PhD (3) · James Guest, MD, PhD (3)
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2023 (3), 2016 (2), 2025 (2), R01NS041503 (2), 1IK1RX004538-01A1 (1), 1IK1RX004813 (1), 1IK1RX005028-01 (1), 1IK2CX000547 (1), 1IK2RD000484-01A1 (1), 1IK2RD002113-01A2 (1), 1RC1EB010915-01 (1), 2004 (1), 2014 (1), 5UE5NS070697-15 (1), I01HX003704 (1)