24 completed, 9 recruiting, 4 not yet recruiting, 4 unknown. 49 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 49 | Completed 24, Recruiting 9, Not yet recruiting 4, Unknown 4, Terminated 3, Enrolling by invitation 2, Withdrawn 2, Active not recruiting 1 |
Follow Spasticity: new trials by email Literature Review of Spasticity trials Research Report on Spasticity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lateral Cord Stimulation as a New Treatment for Refractory Spastic Cerebral Palsy Lateral spinal cord surgical implant of electrodes - Cerebral Palsy, Spasticity | Not applicable | Not yet recruiting | Juan Carlos M. Andreani MD | 40 | 2027-06-01 | 2026-04-28 |
| Addressing Spasticity and Motor Function With Epidural Spinal Cord Stimulation Epidural implant stimulation device - SCI - Spinal Cord Injury, Spasticity | Not applicable | Recruiting | Kessler Foundation | 8 | 2026-10-01 | 2026-10-22 |
| Co-contraction and Corticoreticular Excitability in Spinal Cord Injury Corticoreticular excitability and co-contraction measurement - Spinal Cord Injury, Spasticity | Not applicable | Enrolling by invitation | Taipei Veterans General Hospital, Taiwan | 20 | 2026-07-27 | 2026-10-14 |
| Dorsal Root Electrical Stimulation in Children With Cerebral Palsy Constant Current Stimulator, Cadwell Guardian System - Cerebral Palsy (CP), Cerebral Palsy | Not applicable | Recruiting | Martin Piazza | 15 | 2026-07-16 | 2026-08-11 |
| Effects of Functional Electrical Stimulation on Spasticity, Quadriceps Muscle Strength and Functional Mobility in Individuals With Paraplegia Conventional Neurorehabilitation, Functional Electrical Stimulation (FES) of Quadriceps Muscle, Sham FES group: Conventional neurorehabilitation + sham/placebo FES - Spinal Cord Injury, Paraplegia | Not applicable | Withdrawn | Istanbul Medipol University Hospital | 2026-05-10 | 2026-10-28 | |
| Spinal Cord Stimulation for Children With Cerebral Palsy Transcutaneous Spinal Cord Stimulation (tSCS) - Cerebral Palsy, Spasticity | Not applicable | Recruiting | Martin Piazza | 30 | 2026-03-30 | 2026-04-07 |
| At Home Use of Stimulation Suits for Managing MS Symptoms electro-stimulation suit, Usual Care - Multiple Sclerosis, MS (Multiple Sclerosis) | Not applicable | Recruiting | Daphne Kos | 70 | 2026-03-16 | 2026-10-08 |
| Effects Of Spiral Strapping Systems On Upper Limb Function In Unilateral Spastic Cerebral Palsy TheraTogs® Spiral Strapping System, TogRite™ Spiral Strapping System, Upper Limb Rehabilitation and Home Exercise Program - Cerebral Palsy (CP), Hand Grip Strength | Not applicable | Not yet recruiting | Abant Izzet Baysal University | 27 | 2026-02-15 | 2026-02-18 |
| Leg Stretching Using an Exoskeleton on Demand for People With Spasticity Wearable Robotic Exoskeleton - Spasticity, Movement Disorders | Not applicable | Recruiting | VA Office of Research and Development | 10 | 2026-02-09 | 2026-10-02 |
| Effects of Low-level Laser Therapy on Spasticity and Gait Parameters in Chronic Stroke Patients With Spastic Plantar Flexors Low Level Laser Therapy, conventional physical therapy - Stroke, Spasticity | Not applicable | Completed | Montiha Azeem | 22 | 2025-12-30 | 2026-05-05 |
| Effectiveness of an Interprofessional Approach to the Treatment of Spasticity With Botulinum Toxin & Non-pharmacological Therapies Botulinum Neurotoxin Type A, Non-pharmacological therapies - Spasticity | Not applicable | Not yet recruiting | Technical University of Bern | 30 | 2025-10-01 | 2025-09-08 |
| Static Versus Dynamic Splints for Wrist Spasticity in Stroke Patients Static Wrist-Hand Splint, Dynamic Wrist-Hand Splint - Stroke, Spasticity | Not applicable | Completed | University of Lahore | 20 | 2025-10-01 | 2025-12-24 |
| Pilot Study on Muscle, Tendon, and Neural Changes Post-Botulinum Toxin Injections in Post-stroke Spastic Equinovarus threedimensional freehand ultrasound and instrumented spasticity assessment - Stroke, Spasticity | Not applicable | Recruiting | Universitaire Ziekenhuizen KU Leuven | 12 | 2025-05-02 | 2026-04-29 |
| Efficacy of Shock Wave Therapy in Post-Stroke Muscle Spasticity Management Shock Wave Therapy (SWT), Active Comparator - Conventional Therapy - Stroke, Spasticity | Not applicable | Not yet recruiting | University of Oviedo | 50 | 2025-03-15 | 2025-03-12 |
| Immediate Effects On Gait and Spasticity After The Use Of Passive Kinesiotherapy Equipment In The Lower Limbs Of Neurological Patients Passive mobilization using a device - Hemiparesis, Paraparesis | Not applicable | Enrolling by invitation | Fernanda Trubian | 80 | 2025-03-01 | 2026-05-14 |
| Multicenter Study of Thermal Radiofrequency Applied to the Musculocutaneous Nerve for the Treatment of Spasticity Radiofrequency - Spasticity | Not applicable | Completed | Fundación Pública Galega de Investigación Biomédica INIBIC | 64 | 2025-02-01 | 2026-07-20 |
| The Effect of Kinesiologic Taping on Trunk Control and Balance in Children With Cerebral Palsy kinesiologic taping - Cerebral Palsy (CP), Balance | Not applicable | Completed | Istanbul Rumeli University | 30 | 2025-01-01 | 2025-09-23 |
| Upper Limb Nerve Cryoneurolysis is Non Inferior to the Usual Care and Has Therapeutic Add Value in Dealing With Shoulder Pain and Functional Problems Caused by Spasticity and Motor Impairment Treatment - Hemiplegia, Spasticity | Not applicable | Recruiting | Centre National de Rééducation Fonctionnelle et de Réadaptation | 50 | 2024-12-12 | 2026-03-19 |
| Effects Of Dry Needling On Mobility Among Children With Cerebral Palsy Dry Needling, Cerebral Palsy conventional Treatment - Cerebral Palsy (CP), Spasticity | Not applicable | Completed | Riphah International University | 38 | 2024-09-24 | 2025-01-13 |
| Effect of Callisthenic Training on Mobility and ADL Performance in Spastic Diplegic Cerebral Palsy Patients calisthenic training, Conventional physical therapy group - Activities of Daily Living, Postural Control | Not applicable | Completed | Foundation University Islamabad | 32 | 2024-09-12 | 2025-05-15 |
Showing 20 of 49. Sign in to see all of them.
Muscle Spasticity (49) · Stroke (13) · Cerebral Palsy (11) · Spinal Cord Injuries (10) · Multiple Sclerosis (4) · Hemiplegia (3) · Muscle Hypertonia (3) · Dystonia (2) · Movement Disorders (2) · Pain (2) · Quadriplegia (2) · Ataxia (1) · Brain Injuries, Traumatic (1) · Cerebellar Ataxia (1) · Dysarthria (1)
Muscular Diseases (49) · Musculoskeletal Diseases (49) · Neurologic Manifestations (49) · Neuromuscular Manifestations (49) · Pathological Conditions, Signs and Symptoms (49) · Signs and Symptoms (49) · Nervous System Diseases (48) · Muscle Hypertonia (46) · Central Nervous System Diseases (34) · Brain Diseases (24) · Cardiovascular Diseases (14) · Cerebrovascular Disorders (13) · Vascular Diseases (13) · Brain Damage, Chronic (11) · Spinal Cord Diseases (10)
Dry Needling (6) · Extracorporeal Shockwave Therapy (3) · Electric Stimulation (2) · Transcutaneous Electric Nerve Stimulation (2) · Athletic Tape (1) · Baclofen (1) · Botulinum Toxins, Type A (1) · High-Energy Shock Waves (1) · Low-Level Light Therapy (1) · Magnetic Resonance Spectroscopy (1) · Occupational Therapy (1) · Physical Therapy Modalities (1) · Spinal Puncture (1) · Standard of Care (1) · Therapeutics (1)
Foundation University Islamabad (3) · Kessler Foundation (3) · Martin Piazza (2) · Universidad San Jorge (2) · University of Castilla-La Mancha (2) · Abant Izzet Baysal University (1) · Centre National de Rééducation Fonctionnelle et de Réadaptation (1) · Changhua Christian Hospital (1) · Daphne Kos (1) · Exoneural Network AB (1) · Fernanda Trubian (1) · Fundación Pública Galega de Investigación Biomédica INIBIC (1) · Hacettepe University (1) · Icahn School of Medicine at Mount Sinai (1) · Istanbul Medipol University Hospital (1)
United States (12) · Pakistan (6) · Spain (6) · Taiwan (4) · Belgium (3) · France (2) · Germany (2) · Switzerland (2) · Turkey (Türkiye) (2) · United Kingdom (2) · Argentina (1) · Brazil (1) · Denmark (1) · Egypt (1) · Italy (1)
Martin G Piazza, MD (2) · Andrew Marshall, PhD (1) · Daphne Kos (1) · David R Gater, MD, PhD (1) · David Simpson, MD (1) · David X Cifu, MD (1) · Diego Centonze, MD (1) · Edelle C Field-Fote, PT, PhD (1) · Fabienne Schillebeeckx, MD (1) · Florence S John, MD, MPH (1) · Herrero Pablo, Dr. (1)
PMID 27149465, PMID 32488238, PMID 34894776, PMID 38770827, PMID 41082260
2025 (1), I21RX004652 (1)