114 completed, 10 recruiting, 7 terminated, 5 unknown. 146 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 146 | Completed 114, Recruiting 10, Terminated 7, Unknown 5, Withdrawn 5, Active not recruiting 3, Enrolling by invitation 1, Not yet recruiting 1 |
Follow Smoking Cessation: new trials by email Literature Review of Smoking Cessation trials Research Report on Smoking Cessation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Varenicline for Smoking Cessation in Pancreatitis Varenicline (VAR) - Pancreatitis, Chronic Pancreatitis | Phase 4 | Not yet recruiting | Mayo Clinic | 45 | 2026-11-13 | 2026-10-19 |
| My Path to Quit Tobacco Nicotine patch, Quitline Counseling Phone Calls, Counseling Sessions - Smoking Cessation | Phase 4 | Recruiting | University of Wisconsin, Madison | 1550 | 2026-07-06 | 2026-11-10 |
| Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study) Varenicline, Transcranial Magnetic Stimulation, Transcranial Magnetic Stimulation Sham - Nicotine Dependence, Transcranial Magnetic Stimulation | Phase 4 | Recruiting | Massachusetts General Hospital | 30 | 2026-07-02 | 2026-09-15 |
| The Options 2 Study Nicotine Pouches, Mini Nicotine lozenges - Smoker, Smoking Cessation | Phase 4 | Recruiting | University of Wisconsin, Madison | 300 | 2025-05-21 | 2026-06-22 |
| tDCS Plus Varenicline for Smoking Cessation Active Transcranial Direct Current Stimulation (tDCS), Varenicline 1mg BID, Sham Transcranial Direct Current Stimulation (tDCS) - Nicotine Dependence, Tobacco Smoking | Phase 4 | Recruiting | Centre for Addiction and Mental Health | 160 | 2025-03-10 | 2025-08-12 |
| 12-Month Efficacy of Exercise and Cytisinicline for Tobacco Abstinence Cytisinicline and exercise, Cytisinicline - Smoking Cessation | Phase 4 | Unknown | Maimónides Biomedical Research Institute of Córdoba | 150 | 2025-01-01 | 2024-09-04 |
| Using Multiphase Optimization Strategy (MOST) to Optimize a Cost-effective, Sustainable and Scalable Smoking Cessation Package for Smokers in HIV Clinical Care Motivational Interviewing (MI) Counseling, Peer Mentoring, Skills-based Text Messaging - Human Immunodeficiency Virus (HIV), Smoking Cessation | Phase 4 | Recruiting | New York University | 500 | 2024-10-18 | 2026-11-12 |
| The Avenues Study: Dual Use Cessation Varenicline, Nicotine patch, Dual Focused Cessation Counseling - Smoking Cessation, Electronic Cigarette Use | Phase 4 | Recruiting | University of Wisconsin, Madison | 500 | 2024-09-24 | 2026-10-07 |
| Transcranial Magnetic Stimulation for Nicotine Dependence: An Effectiveness-Implementation Trial Brainsway H4 deep Repetitive Transcranial Magnetic Stimulation (rTMS) coil, Nicotine replacement - Tobacco Use Disorder, Psychiatric Disorder | Phase 4 | Recruiting | Centre for Addiction and Mental Health | 40 | 2024-09-01 | 2025-12-11 |
| Project HOPES: Healthy Options for Pain and Ending Smoking. A Program for Cancer Survivors. Smoking cessation and pain management intervention, Varenicline - Smoking Cessation, Pain | Phase 4 | Completed | Duke University | 21 | 2024-07-15 | 2026-08-25 |
| Smoking Cessation Program in the Construction Sector Nicorette, Tobacco Quit-line, Brief Behavioral Counseling - Smoking Cessation, Tobacco Use Cessation | Phase 4 | Active not recruiting | University of Miami | 608 | 2024-04-10 | 2026-08-21 |
| Implementation of Transcranial Magnetic Stimulation for Smoking Cessation Brainsway H4 deep rTMS coil and Brainsway stimulator system - Smoking | Phase 4 | Recruiting | Centre for Addiction and Mental Health | 40 | 2024-03-30 | 2026-03-27 |
| Treating Caregivers Who Smoke at AFCH Nicotine Replacement Product - Smoking, Smoking Cessation | Phase 4 | Completed | University of Wisconsin, Madison | 23 | 2024-03-05 | 2026-04-16 |
| Tobacco Treatment Comparison for Cancer Care Transdermal Nicotine Patch, Standard Telephone Counseling, Varenicline - Smoking Cessation, Cancer | Phase 4 | Completed | University of Wisconsin, Madison | 52 | 2024-03-01 | 2025-10-27 |
| Botswana Smoking and Abstinence Reinforcement Trial Screening, Brief Intervention and Referral to Treatment (SBIRT) intervention consisting of the 5As, (Ask, Advise, Assess, Assist, Arrange), Varenicline - Smoking Cessation, Hiv | Phase 4 | Enrolling by invitation | University of Maryland, Baltimore | 750 | 2023-07-25 | 2026-01-09 |
| BREATHE 2 Clinic Stop-Smoking Treatment Outreach Study Text message smoking treatment, Nicotine replacement therapy sampling, Wisconsin Tobacco QuitLine Referral - Quitting Smoking, Smoking Cessation | Phase 4 | Completed | University of Wisconsin, Madison | 12376 | 2023-07-24 | 2026-06-26 |
| TOBacco STOP in Chronic Obstructive Pulmonary Disease-Trial - Study Protocol High-intensity smoking cessation intervention, Low-intensity smoking cessation intervention - Chronic Obstructive Pulmonary Disease, Smoking Cessation | Phase 4 | Withdrawn | Pradeesh Sivapalan | 2023-07-01 | 2023-02-23 | |
| Cytisine for Smoking Cessation Cytisine, Placebo - Tobacco Use Disorder, Alcohol Use Disorder | Phase 4 | Completed | Centre for Addiction and Mental Health | 20 | 2023-02-08 | 2026-02-27 |
| Smoking Cessation and Menstrual Cycle Phase Timing of nicotine replacement therapy start date, Nicotine Replacement Therapy Agent - Nicotine Dependence, Tobacco Smoking | Phase 4 | Recruiting | Centre for Addiction and Mental Health | 1200 | 2022-11-30 | 2026-03-19 |
| Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and Children Progesterone 200 MG Oral Capsule - Smoking, Smoking Cessation | Phase 4 | Recruiting | University of Minnesota | 171 | 2022-04-14 | 2026-07-13 |
Showing 20 of 146. Sign in to see all of them.
Tobacco Use Disorder (44) · Smoking (39) · Schizophrenia (11) · Cigarette Smoking (8) · Psychotic Disorders (7) · Tobacco Smoking (6) · Mental Disorders (5) · Substance-Related Disorders (5) · Tobacco Use Cessation (5) · Vaping (5) · Acquired Immunodeficiency Syndrome (4) · Pulmonary Disease, Chronic Obstructive (4) · Recurrence (4) · Alcoholism (3)
Behavior (146) · Health Behavior (145) · Mental Disorders (54) · Chemically-Induced Disorders (48) · Substance-Related Disorders (43) · Smoking (15) · Pathological Conditions, Signs and Symptoms (14) · Pathologic Processes (11) · Schizophrenia Spectrum and Other Psychotic Disorders (11) · Disease Attributes (10) · Tobacco Use (10) · Immune System Diseases (7) · Infections (7) · Tobacco Smoking (7) · Blood-Borne Infections (5)
Varenicline (54) · Tobacco Use Cessation Devices (39) · Bupropion (22) · Nicotine (17) · Nicotine Replacement Therapy (17) · Nicotine Chewing Gum (14) · Counseling (8) · Motivational Interviewing (7) · Behavior Therapy (5) · Crisis Intervention (4) · Transdermal Patch (4) · BID protein, human (3) · Chewing Gum (3) · cytisine (3) · Nebulizers and Vaporizers (2)
University of Wisconsin, Madison (18) · Pfizer (11) · Centre for Addiction and Mental Health (9) · Massachusetts General Hospital (7) · Duke University (5) · Ottawa Heart Institute Research Corporation (5) · University of Miami (5) · University of Alabama at Birmingham (3) · University of California, San Francisco (3) · Yale University (3) · National Institute on Drug Abuse (NIDA) (2) · North Suffolk Mental Health Association (2) · Shaare Zedek Medical Center (2) · Stanford University (2) · Swedish Match AB (2)
United States (99) · Canada (22) · Germany (8) · Brazil (5) · France (5) · Mexico (5) · Spain (5) · Australia (4) · Russia (4) · United Kingdom (4) · Argentina (3) · Czechia (3) · Denmark (3) · Finland (3) · South Africa (3)
Andrew Pipe, MD (4) · A Eden Evins, MD, MPH (3) · Megan Piper, PhD (3) · Taghrid Asfar, MD (3) · Anne M. Joseph, MD MPH (2) · Danielle E McCarthy, PhD (2) · Jessica Cook, PhD (2) · Laurie A Zawertailo, PhD (2) · Laurie Zawertailo, PhD (2) · Megan E Piper, PhD (2) · Michael C Fiore, MD, MPH, MBA (2) · Nancy A Rigotti, MD (2) · Peter Selby, MD, MHSc (2)
PMID 37142273, PMID 37230961, PMID 37335995, PMID 34611902, PMID 39868569, PMID 26336372, PMID 10191796, PMID 10417762, PMID 10493090, PMID 10510989, PMID 10581887, PMID 10740940, PMID 10748642, PMID 10791509, PMID 10812284, PMID 10885042, PMID 10901493, PMID 11176814, PMID 11236847, PMID 11260806, PMID 11282701, PMID 11377644, PMID 11516593, PMID 12010856, PMID 1202204, PMID 12028847, PMID 12047734, PMID 12095672, PMID 12438835, PMID 12439223, PMID 12492263, PMID 12814497, PMID 1453243, PMID 14982685, PMID 15010446, PMID 1511534, PMID 15138759, PMID 15203809, PMID 15370156, PMID 15370939, PMID 15539711, PMID 15586837, PMID 15631608, PMID 15820329, PMID 15955146, PMID 16036283, PMID 16123753, PMID 1613610, PMID 16157462, PMID 16203030
P01CA180945 (4), P50CA143188 (3), 1RC1CA144382-01 (1), K01DA043413 (1), K02DA034767 (1), K23DA038717 (1), K23RR018471 (1), R01CA165080 (1), R01CA184211 (1), R01CA218156 (1), R01CA290895 (1), R01CA291761 (1), R01DA004174 (1), R01DA017441 (1), R01DA021245 (1)