11 completed, 2 terminated, 1 withdrawn. 14 Phase 1, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 14 | Completed 11, Terminated 2, Withdrawn 1 |
| Phase 2 | 7 | Completed 6, Terminated 1 |
Follow Sinusitis: new trials by email Literature Review of Sinusitis trials Research Report on Sinusitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 1 Study of Cizutamig in IgE Mediated Diseases Cizutamig - IgE-Mediated Hypersensitivity, IgE Mediated Food Allergy | Phase 1 | Withdrawn | Candid Therapeutics | 2026-04-01 | 2026-07-22 | |
| SynRinse Irrigation Pilot (SIP) Trial Synrinse - Sinusitis, Chronic, Cystic Fibrosis With Other Manifestations | Phase 1 / Phase 2 | Completed | University of Washington | 30 | 2017-06-06 | 2018-10-17 |
| Trial of Topical Verapamil in Chronic Rhinosinusitis With Nasal Polyps Verapamil Hydrochloride Intranasal - Sinusitis, Nasal Polyps | Phase 1 | Terminated | Benjamin Bleier | 6 | 2017-06-05 | 2019-07-23 |
| Adrenaline Solution Irrigation and Bleeding During Sinus Surgery Adrenaline saline irrigation - Chronic Rhinosinusitis (Diagnosis) | Phase 1 | Completed | Jordan University of Science and Technology | 60 | 2016-07-01 | 2020-09-16 |
| SinuSurf vs. Saline Solution in Normal Subjects SinuSurf irrigation twice daily, NeilMed Sinus rinse irrigation twice daily - Rhinosinusitis | Phase 1 | Completed | Vanderbilt University Medical Center | 40 | 2016-04-12 | 2017-03-14 |
| The Effectiveness of Topical Silver Colloid in Treating Patients With Recalcitrant Chronic Rhinosinusitis Silver Colloid, Saline - Rhinosinusitis | Phase 1 / Phase 2 | Completed | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 22 | 2015-12-10 | 2019-11-15 |
| Buparid/PARI SINUS Versus Budes® Nasal Spray in the Therapy of Chronic Rhinosinusitis Budesonide - Rhinosinusitis | Phase 1 / Phase 2 | Completed | Pari Pharma GmbH | 19 | 2015-10-27 | 2022-04-12 |
| Topical Irrigation Therapy for CRS Quinine Sulfate, Placebo - Rhinitis, Sinusitis | Phase 1 / Phase 2 | Terminated | University of Pennsylvania | 10 | 2015-10-01 | 2019-03-13 |
| Buparid/PARI SINUS Versus Budes® Nasal Spray in the Therapy of Chronic Rhinosinusitis With Polyposis Nasi Budesonide - Rhinosinusitis, Chronic Polyposis | Phase 1 / Phase 2 | Completed | Pari Pharma GmbH | 14 | 2013-08-28 | 2022-04-12 |
| Safety and Performance of the SinuSys Dilation System for Dilation of the Maxillary Sinus Ostium SinuSys Dilation System - Sinusitis | Phase 1 | Completed | SinuSys Corporation | 36 | 2012-04-01 | 2014-11-05 |
| Manuka Honey Irrigation After Sinus Surgery Manuka Honey, Saline Irrigation - Sinusitis | Phase 1 / Phase 2 | Completed | St. Paul's Hospital, Canada | 78 | 2011-06-01 | 2013-12-04 |
| Treatment of Acute Rhino-Sinusitis With Essential Oils of Aromatic Plants mixture of aromatic essential oils., placebo - Rhino-Sinusitis | Phase 1 / Phase 2 | Completed | HaEmek Medical Center, Israel | 14 | 2008-01-01 | 2008-06-17 |
| Concentration of Itraconazole Solution in Nasal Secretions Itraconazole - Sinusitis | Phase 1 | Completed | Mayo Clinic | 6 | 2007-04-01 | 2015-04-14 |
| Pharmacokinetic Profiles Of Amoxicillin 2000 mg And Clavulanate 125 mg In Adolescent Patients amoxicillin/clavulanate potassium - Infections, Respiratory Tract | Phase 1 | Completed | GlaxoSmithKline | 52 | 2006-01-19 | 2017-08-01 |
Rhinosinusitis (6) · Nasal Polyps (2) · Asthma (1) · Bronchiolitis Obliterans Syndrome (1) · Dermatitis, Atopic (1) · Disease (1) · Egg Hypersensitivity (1) · Food Hypersensitivity (1) · Hypersensitivity, Immediate (1) · Milk Hypersensitivity (1) · Nut Hypersensitivity (1) · Peanut Hypersensitivity (1) · Respiratory Tract Infections (1) · Rhinitis (1)
Infections (14) · Nose Diseases (14) · Otorhinolaryngologic Diseases (14) · Paranasal Sinus Diseases (14) · Respiratory Tract Diseases (14) · Respiratory Tract Infections (13) · Rhinitis (6) · Bronchial Diseases (2) · Immune System Diseases (2) · Lung Diseases (2) · Lung Diseases, Obstructive (2) · Pathological Conditions, Anatomical (2) · Pathological Conditions, Signs and Symptoms (2) · Polyps (2)
Budesonide (2) · Amoxicillin-Potassium Clavulanate Combination (1) · Itraconazole (1) · Quinine (1) · Sodium Chloride (1) · Therapeutic Irrigation (1) · colloidal silver (1)
Pari Pharma GmbH (2) · Benjamin Bleier (1) · Candid Therapeutics (1) · GlaxoSmithKline (1) · HaEmek Medical Center, Israel (1) · Jordan University of Science and Technology (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · Mayo Clinic (1) · SinuSys Corporation (1) · St. Paul's Hospital, Canada (1) · University of Pennsylvania (1) · University of Washington (1) · Vanderbilt University Medical Center (1)
United States (7) · Canada (3) · Germany (2) · Australia (1) · Israel (1) · United Kingdom (1)
Amin Javer, MD (1) · Amin R Javer, MD, FRCSC (1) · Benjamin S Bleier, MD (1) · Greg Davis, MD (1) · Hirohito Kita, MD (1) · Justin Turner, MD, PhD (1) · Leigh Sowerby, MD (1) · Martin Canis, MD (1) · Mohannad A Al-Qudah, MD,FACS (1) · Peter Catalano, MD (1) · Rakesh K. Chandra, MD (1) · Sven Becker, MD (1) · Yoseph Rakover, M.D. (1)
PMID 15125017, PMID 19559969, PMID 19794023, PMID 21271600, PMID 23255493, PMID 25137523, PMID 26452438, PMID 28922579, PMID 29178954