26 completed, 4 terminated, 4 unknown, 3 recruiting. 39 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 39 | Completed 26, Terminated 4, Unknown 4, Recruiting 3, Active not recruiting 1, Withdrawn 1 |
Follow Sinusitis: new trials by email Literature Review of Sinusitis trials Research Report on Sinusitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparative Effectiveness of Available Treatments for Sinus and Ear Infections in Children (Acute Sinusitis) Amoxicillin, Amoxi Clavulanate, Amoxicillin Placebo - ACUTE SINUSITIS, Sinusitis | Phase 4 | Recruiting | Nader Shaikh | 1100 | 2026-10-01 | 2026-10-20 |
| Biologics in Chronic Rhinosinusitis With Nasal Polyposis Biologic Agents - Chronic Sinusitis, Nasal Polyps | Phase 4 | Recruiting | Medical University of South Carolina | 504 | 2026-06-03 | 2026-11-10 |
| Dexmedetomidine Infusion in Either Total Intravenous Anesthesia or Inhalational Anesthesia to Improve Surgical Field Visibility in Endoscopic Sinus Surgery functional endoscopic sinus surgery, Dexmedetomidine - Rhinosinusitis | Phase 4 | Completed | Menoufia University | 50 | 2024-05-01 | 2025-09-08 |
| Nasal Steroids, Irrigation, Oral Antibiotics, and Subgroup Targeting for Effective Management of Acute Sinusitis amoxicillin/clavulanate potassium, Placebo, Budesonide nasal spray - Sinus Infection, Acute Sinusitis | Phase 4 | Recruiting | Daniel Merenstein | 3720 | 2023-11-21 | 2026-03-03 |
| Dupixent Study for Alternate Administration Dupilumab - Nasal Polyps, Sinusitis | Phase 4 | Active not recruiting | Madigan Army Medical Center | 30 | 2021-10-14 | 2025-01-17 |
| Erenumab for Idiosyncratic Facial Pain Erenumab Prefilled Syringe, Placebo - Facial Pain, Rhinosinusitis | Phase 4 | Completed | David Jang, M.D. | 29 | 2021-02-10 | 2024-09-24 |
| Type and Frequency of Nasal Irrigation in Rhinosinusitis Patients Isotonic Saline ( 0.9% Sodium Chloride Saline), Hypertonic Saline ( 3% Sodium Chloride Saline) - Otorhinolaryngologic Diseases, Rhinosinusitis | Phase 4 | Unknown | Imam Abdulrahman Bin Faisal University | 100 | 2020-02-01 | 2020-01-22 |
| Pain Control Following Sinus Surgery OxyCODONE 5 Mg (milligram) Oral Tablet, Ibuprofen 600 Mg (milligram) Oral Tablet, Acetaminophen 650 MG (milligram) Oral Tablet - Sinusitis, Opioid Use | Phase 4 | Completed | Stanford University | 118 | 2019-04-04 | 2021-09-01 |
| Effectiveness of Mometasone Nasal Irrigation for Chronic Rhinosinusitis Mometasone Furoate Nasal Irrigation, Mometasone Nasal Spray - Chronic Rhinosinusitis (Diagnosis), Allergic Rhinosinusitis | Phase 4 | Completed | Washington University School of Medicine | 53 | 2019-01-01 | 2025-06-26 |
| Treatment of Acute Sinusitis With High-Dose vs. Standard-Dose Amoxicillin/Clavulanate Amoxicillin 875 mg, Placebo (lactase) - Sinusitis, Acute | Phase 4 | Terminated | Paul Sorum, MD | 157 | 2018-02-26 | 2021-08-12 |
| Response of the Airway in Sinusitis and Asthma Mometasone Nasal, placebo mometasone - Sinusitis, Asthma | Phase 4 | Completed | Medical University of Lodz | 150 | 2017-01-01 | 2019-08-13 |
| The Efficacy and Complication of Gentamicin Nasal Irrigation in Chronic Rhinosinusitis and Recurrent Sinusitis Gentamicin nasal irrigation, Normal saline nasal irrigation - Rhinosinusitis | Phase 4 | Unknown | Mahidol University | 40 | 2017-01-01 | 2018-08-20 |
| The Impact Of The Addition Of Budesonide To Low-Pressure, High-Volume Saline Sinus Irrigation For Chronic Rhinosinusitis Budesonide, Saline alone - Rhinosinusitis, Chronic Eosinophilic Rhinosinusitis | Phase 4 | Completed | Washington University School of Medicine | 80 | 2016-01-01 | 2019-09-03 |
| Clinical Trial of the Treatment of Acute Sinusitis With Standard-dose Versus High-dose Amoxicillin/Clavulanate standard dose amoxicillin/clavulanate, high dose amoxicillin/clavulanate - Sinusitis | Phase 4 | Completed | Albany Medical College | 315 | 2014-11-18 | 2017-08-24 |
| The Optimal Head Position for Distributing Topical Nasal Medication Using the Mucosal Atomization Device Lying Head Back Position, Head Down and Forward Position - Sinusitis | Phase 4 | Completed | St. Paul's Hospital, Canada | 66 | 2014-06-01 | 2016-04-14 |
| Comparison of Daily Mometasone Furoate Nasal Spray Alone Versus a Combination With Montelukast for Treatment of Chronic Rhinosinusitis With Asthma After Functional Endoscopic Sinus Surgery Montelukast, mometasone furoate nasal spray - Sinusitis, Nasal Polyps | Phase 4 | Completed | First Affiliated Hospital, Sun Yat-Sen University | 50 | 2014-06-01 | 2020-11-23 |
| Prophylactic Antibiotics After Functional Endoscopic Sinus Surgery: a Randomized, Double-blind Placebo Controlled Trial Amoxicillin-Potassium Clavulanate, Placebo - Sinusitis | Phase 4 | Completed | Massachusetts Eye and Ear Infirmary | 134 | 2013-02-01 | 2020-02-25 |
| Duration of Antibiotic Therapy as Part of Maximal Medical Therapy for Chronic Rhinosinusitis Doxycycline, Azithromycin, Augmentin - Sinusitis | Phase 4 | Completed | University of North Carolina, Chapel Hill | 40 | 2013-02-01 | 2017-04-04 |
| Clinical Trial for the Assessment of Delayed Antibiotic Treatment in Pediatric (DAP-Pediatrics) Antibiotic prescription strategies - Rhinosinusitis, Acute Bronchitis | Phase 4 | Completed | Asociacion Colaboracion Cochrane Iberoamericana | 450 | 2012-06-01 | 2017-07-31 |
| Study of Cefditoren Pivoxil in Treatment of Childhood With Acute Rhinosinusitis cefditoren pivoxil - Rhinosinusitis | Phase 4 | Unknown | Thammasat University | 120 | 2012-01-01 | 2012-03-14 |
Showing 20 of 39. Sign in to see all of them.
Rhinosinusitis (15) · Nasal Polyps (4) · Asthma (3) · Bronchitis (3) · Bronchiolitis Obliterans Syndrome (2) · Maxillary Sinusitis (2) · Otorhinolaryngologic Diseases (2) · Personal Satisfaction (2) · Rhinitis (2) · Rhinitis, Allergic, Perennial (2) · Anosmia (1) · Bacterial Infections (1) · Chronic Disease (1) · Disease (1)
Infections (39) · Nose Diseases (39) · Paranasal Sinus Diseases (39) · Respiratory Tract Diseases (39) · Respiratory Tract Infections (38) · Otorhinolaryngologic Diseases (37) · Rhinitis (14) · Pathological Conditions, Signs and Symptoms (9) · Bronchial Diseases (7) · Lung Diseases (7) · Lung Diseases, Obstructive (7) · Immune System Diseases (6) · Hypersensitivity (5) · Hypersensitivity, Immediate (5)
Amoxicillin-Potassium Clavulanate Combination (6) · Amoxicillin (4) · Mometasone Furoate (3) · Acetaminophen (2) · Azithromycin (2) · Budesonide (2) · Guaifenesin (2) · Moxifloxacin (2) · Pseudoephedrine (2) · Sodium Chloride (2) · telithromycin (2) · Acetylcysteine (1) · Amiloride (1) · Biological Factors (1) · Clavulanic Acid (1)
Washington University School of Medicine (3) · Bayer (2) · St. Paul's Hospital, Canada (2) · Adams Respiratory Therapeutics (1) · Albany Medical College (1) · Asociacion Colaboracion Cochrane Iberoamericana (1) · CPL Associates (1) · Carbylan Therapeutics, Inc. (1) · Clinvest (1) · Daniel Merenstein (1) · David Jang, M.D. (1) · Ethicon, Inc. (1) · First Affiliated Hospital, Sun Yat-Sen University (1) · Friedrich-Alexander-Universität Erlangen-Nürnberg (1) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (1)
United States (23) · Canada (3) · Italy (2) · Spain (2) · Thailand (2) · Argentina (1) · China (1) · Egypt (1) · Finland (1) · Poland (1) · Saudi Arabia (1)
Jay F Piccirillo, MD (2) · Pablo Alonso Coello, PhD (2) · Adam Zanation, MD (1) · Aila Kristo, MD (1) · Amin R Javer, MD, FRCSC, FARS (1) · Amin R Javer, MD, FRCSC,FARS (1) · Andrew N. Goldberg, MD (1) · Anna Marttila, MD (1) · Anne Dixon, MD (1) · Dan Merenstein, MD (1) · David Jang, MD (1) · Eric H Holbrook, MD (1) · Gaetano Paludetti, MD (1)
PMID 17424883, PMID 18559163, PMID 19344620, PMID 21038023, PMID 21453656, PMID 21844413, PMID 22337680, PMID 23682979, PMID 26719947, PMID 28870448, PMID 29337030, PMID 29738561, PMID 29879268, PMID 33222307, PMID 33340285, PMID 33755168, PMID 34351376, PMID 34510485, PMID 36848113, PMID 37784098, PMID 37990964, PMID 42418237
2005 (1), R37HL068546 (1), U01AI064655 (1)