13 terminated. 13 Phase 3, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 13 | Terminated 13 |
| Phase 2 | 5 | Terminated 5 |
Follow Septic Shock: new trials by email Literature Review of Septic Shock trials Research Report on Septic Shock
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Vitamin C, Placebo - Sepsis, Septic Shock | Phase 3 | Terminated | Hospital Sirio-Libanes | 71 | 2021-08-01 | 2024-01-30 |
| Evaluation of the Effect of Dexmedetomidine on Phenylephrine Response During Refractory Septic Shock Dexmedetomidine 100 Mcg/mL Intravenous Solution, 5% glucose Infusion solution - Septic Shock, Vasopressor Resistance | Phase 3 | Terminated | Centre Hospitalier Universitaire Dijon | 32 | 2019-10-27 | 2026-02-04 |
| Albumin Replacement Therapy in Septic Shock Albutein® 200 g/L or Plasbumin® 20 - Septic Shock | Phase 3 | Terminated | Jena University Hospital | 440 | 2019-10-21 | 2024-10-28 |
| Effect of IV Vitamin C, Thiamine, and Steroids on Mortality of Septic Shock Vitamin C, Normal saline - Septic Shock | Phase 3 | Terminated | New York Presbyterian Brooklyn Methodist Hospital | 3 | 2019-10-15 | 2020-02-10 |
| Midodrine Use in Septic Shock Midodrine Hydrochloride, placebo - Septic Shock | Phase 3 | Terminated | University of Virginia | 10 | 2018-11-05 | 2025-09-24 |
| Evaluation of Hydrocortisone, Vitamin C and Thiamine for the Treatment of Septic Shock Triple therapy group - Septic Shock, Critical Illness | Phase 2 / Phase 3 | Terminated | Hamad Medical Corporation | 106 | 2018-03-17 | 2021-12-10 |
| Selepressin Evaluation Programme for Sepsis-Induced Shock - Adaptive Clinical Trial selepressin, placebo - Septic Shock | Phase 2 / Phase 3 | Terminated | Ferring Pharmaceuticals | 868 | 2015-07-01 | 2021-04-06 |
| Effect of Hydrocortison on Post-ischemic Flow-mediated Dilation and on Thenar Oxygen Saturation in Human Septic Shock. hydrocortison hemisuccinate, placebo followed by hydrocortisone hemisuccinate - Septic Shock, Adult | Phase 2 / Phase 3 | Terminated | Centre Hospitalier Régional d'Orléans | 10 | 2013-11-05 | 2020-02-11 |
| Upregulation of Alpha-1 Receptors Upon Septic Shock? Clonidine, Placebo - Septic Shock | Phase 2 / Phase 3 | Terminated | Direction Centrale du Service de Santé des Armées | 40 | 2013-08-01 | 2017-07-28 |
| I.D.E.A.L.-I.C.U. (Initiation of Dialysis EArly Versus deLayed in Intensive Care Unit) Renal Remplacement Therapy - Septic Shock, Acute Renal Failure (as Defined by the "Failure" Stage of the RIFLE Classification) | Phase 3 | Terminated | Centre Hospitalier Universitaire Dijon | 500 | 2012-07-01 | 2026-02-09 |
| Hypertonic Saline and Terlipressin for Sepsis-associated Hypotension Hypertonic Saline and Terlipressin, Normal saline and norepinephrine - Septic Shock, Sepsis-associated Hypotension | Phase 3 | Terminated | Hospital General de Ciudad Real | 21 | 2012-06-01 | 2014-03-10 |
| The Cooling And Surviving Septic Shock Study (CASS) Mild Induced Hypothermia - Septic Shock | Phase 2 / Phase 3 | Terminated | Danish Procalcitonin Study Group | 433 | 2011-11-01 | 2016-11-22 |
| GCIV as an Adjuvant Therapy for Community-Acquired Severe Sepsis or Septic Shock Immunoglobulin G - Severe Sepsis, Septic Shock | Phase 3 | Terminated | Green Cross Corporation | 214 | 2009-10-01 | 2013-04-30 |
Shock, Septic (13) · Sepsis (4) · Acute Kidney Injury (1) · Critical Illness (1)
Infections (13) · Inflammation (13) · Pathologic Processes (13) · Pathological Conditions, Signs and Symptoms (13) · Shock (13) · Systemic Inflammatory Response Syndrome (13) · Sepsis (9) · Disease Attributes (1) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Kidney Diseases (1) · Male Urogenital Diseases (1) · Renal Insufficiency (1) · Urogenital Diseases (1) · Urologic Diseases (1)
Ascorbic Acid (3) · Thiamine (3) · Hydrocortisone (2) · Saline Solution (2) · Albumins (1) · Clonidine (1) · Cool-Down Exercise (1) · Dexmedetomidine (1) · Glucose (1) · Hypothermia, Induced (1) · Immunoglobulin G (1) · Midodrine (1) · Norepinephrine (1) · Saline Solution, Hypertonic (1) · Terlipressin (1)
Centre Hospitalier Universitaire Dijon (2) · Centre Hospitalier Régional d'Orléans (1) · Danish Procalcitonin Study Group (1) · Direction Centrale du Service de Santé des Armées (1) · Ferring Pharmaceuticals (1) · Green Cross Corporation (1) · Hamad Medical Corporation (1) · Hospital General de Ciudad Real (1) · Hospital Sirio-Libanes (1) · Jena University Hospital (1) · New York Presbyterian Brooklyn Methodist Hospital (1) · University of Virginia (1)
France (5) · United States (4) · Denmark (2) · Netherlands (2) · Belgium (1) · Brazil (1) · Germany (1) · Qatar (1) · South Korea (1) · Spain (1)
Adham Mohamed, PharmD (1) · Alexandra Kadl, MD (1) · Gisele Queiroz, MD (1) · Jens Ulrik S Jensen, MD, PhD (1) · Liam Gross, DO (1) · Luciano CP Azevedo, PhD (1) · Min Ja Kim, Professor (1) · Mohamed Abdelaty, MD (1) · Thierry Boulain, MD (1) · Yasser Sakr, MD, PhD (1)
PMID 10722036, PMID 1138591, PMID 11502226, PMID 12454520, PMID 12545007, PMID 12700374, PMID 1607900, PMID 16570523, PMID 18353115, PMID 20332511, PMID 20646908, PMID 227054, PMID 23525934, PMID 24484547, PMID 24838355, PMID 25466837, PMID 26771781, PMID 26903338, PMID 27162802, PMID 27695824, PMID 27940189, PMID 28098591, PMID 29325753, PMID 29388815, PMID 30304656, PMID 30673539, PMID 31577035, PMID 33287911, PMID 36017005, PMID 36416787, PMID 36870070, PMID 3928249, PMID 40019329, PMID 41712212, PMID 8615361, PMID 8625625
2014 (1), 2018 (1)