425 completed, 152 unknown, 117 recruiting, 48 active not recruiting. 417 Not applicable, 114 Phase 2, 73 Phase 1, 48 Phase 3, 37 Early Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| VergeRx for Smokers Not Ready to Quit VergeRx, SmokefreeTXT, NRT Lozenge (Combination) - Tobacco Use Cessation | Not applicable | Not yet recruiting | University of Virginia | 592 | 2027-12-01 | 2026-07-09 |
| Reciprocal Innovation to Optimize Low-Tech Augmentative and Alternative Communication (AAC) for Individuals Automated AAC Assessment and Low-Tech AAC Implementation Support, Standard AAC Support - Autism, Neurodevelopment | Not applicable | Not yet recruiting | Indiana University | 500 | 2027-06-01 | 2026-05-12 |
| SniffTrain: Effectiveness of Sniff Training in the Treatment of Post-Viral Anosmia Sniff Training Kits - Post-viral Anosmia, Anosmia | Not applicable | Not yet recruiting | University of Virginia | 204 | 2027-01-05 | 2026-10-05 |
| Social Media and Risk-reduction Training for Preterm Infant Care Practices Safe Sleep NICU Quality Improvement Campaign, Shared Reading NICU Quality Improvement Campaign, Safe Sleep TodaysNICUBaby videos and messages - Safe Sleep Education, SUID | Not applicable | Not yet recruiting | University of Massachusetts, Worcester | 1600 | 2027-01-01 | 2026-05-13 |
| Collaborative Research: Multiscale Modeling and Intervention for Improving Long-Term Medication integrated medication monitoring (MM) system - Breast Cancer Survivor, Breast Cancer Early Stage Breast Cancer (Stage 1-3) | Not applicable | Not yet recruiting | San Diego State University | 15 | 2026-12-01 | 2026-10-05 |
| Exercise Training Intensity and Nitrate Supplementation in Post-Menopausal Females on Hormone Therapy Moderate Intensity Exercise (MIE), High intensity exercise (HIE), Control (No exercise) - Postmenopausal Female Patients, Vasomotor Symptoms | Not applicable | Not yet recruiting | University of Virginia | 24 | 2026-10-15 | 2026-10-16 |
| Post-exercise Blood Pressure With Inorganic Nitrate Beetroot Juice - Active + Exercise, Beetroot juice placebo + Exercise, Beetroot Juice - Active + No exercise - Obese Individuals, Central Adiposity | Not applicable | Not yet recruiting | University of Virginia | 12 | 2026-10-15 | 2026-10-09 |
| Neoadjuvant Avutometinib/Defactinib and mFOLFIRINOX Combination Therapy in Pancreatic Adenocarcinoma Avutometinib (VS-6766) + Defactinib (VS-6063) - Pancreatic Cancer, PDAC - Pancreatic Ductal Adenocarcinoma | Phase 1 / Phase 2 | Not yet recruiting | University of Virginia | 31 | 2026-10-01 | 2026-09-17 |
| STeroids and Enhanced Spectrum Antibiotics for the Treatment of Patients in Africa With Refractory Sepsis Hydrocortisone administration, Expanded antimicrobial therapy - Sepsis, Tuberculosis | Phase 3 | Not yet recruiting | University of Virginia | 344 | 2026-10-01 | 2026-06-01 |
| Echocardiographic Molecular Imaging for POC Detection of Ischemia Myocardial Contrast Echo (MCE) molecular imaging with Sonazoid - Acute Coronary Syndrome | Early Phase 1 | Not yet recruiting | University of Virginia | 80 | 2026-09-30 | 2026-08-20 |
| Evaluating the Impact of Digital Behavioral Interventions to Address Insomnia and Depression in Breast Cancer Survivors Using an Adaptive Design Digital Insomnia Program, Digital Mental Health Program, Psychoeducation - Insomnia, Depression | Not applicable | Not yet recruiting | University of Virginia | 747 | 2026-09-30 | 2026-07-24 |
| MCE Molecular Imaging for Myocarditis Myocardial contrast echocardiography molecular imaging for inflammation - Myocarditis Acute | Early Phase 1 | Not yet recruiting | University of Virginia | 30 | 2026-09-15 | 2026-08-20 |
| Trial of Total Lung Protective Ventilation in Adult VV-ECMO Patients With Severe ARDS Mechanical Power Targeted Ventilation - ARDS (Acute Respiratory Distress Syndrome), VV ECMO | Not applicable | Not yet recruiting | University of Virginia | 24 | 2026-09-01 | 2026-09-01 |
| Feasibility of a Medical-Legal Partnership Model to Connect Coal Miners QuitAid QuitAid (pharmacist-delivered MTM), Nicotine Replacement Therapy (NRT) - Tobacco Use Cessation, Tobacco Use Disorder | Not applicable | Not yet recruiting | University of Virginia | 120 | 2026-09-01 | 2026-07-10 |
| This Study Will Evaluate Cardiorespiratory and Muscular Fitness to Examine Associations With Anthropometric Characteristics and Other Indicators of Cardiometabolic Risk Among Patients With or Without Autism Spectrum Disorder Autism Spectrum Disorder (ASD), Cardiometabolic Health Indicators | Recruiting | University of Virginia | 200 | 2026-08-05 | 2026-09-04 | |
| The Effect of Exercise and Tirzepatide on Weight and Health Outcomes (EXER-MED) Tirzepatide, Exercise - Obesity & Overweight | Phase 3 | Not yet recruiting | University of Virginia | 24 | 2026-08-01 | 2026-05-06 |
| Pre-Radiation Chemotherapy for Newly Diagnosed High-Grade Glioma. Pre-radiation temozolomide. - High Grade Gliomas, Glioblastoma | Phase 2 | Recruiting | The Cooper Health System | 70 | 2026-07-13 | 2026-10-09 |
| A Pre-post Pilot of a Smartphone Intervention Digital Micro-Interventions - Mental Health Issue, Breast Cancer | Not applicable | Not yet recruiting | University of Virginia | 44 | 2026-07-01 | 2026-06-24 |
| CARRII Native Intervention Optimization Trial CARRII Native Cores - Fetal Alcohol Spectrum Disorders, Pregnancy | Not applicable | Recruiting | University of Virginia | 512 | 2026-06-02 | 2026-06-23 |
| HER2 FPBMC in Patients With Metastatic Breast and Prostate Cancer (AM006) HER2 FPBMC - Breast Cancer, Prostate Cancer | Phase 1 / Phase 2 | Recruiting | University of Virginia | 23 | 2026-06-01 | 2026-06-12 |
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Diabetes Mellitus, Type 1 (81) · Obesity (29) · Polycystic Ovary Syndrome (27) · Motor Activity (26) · Diabetes Mellitus (21) · Breast Neoplasms (20) · Diabetes Mellitus, Type 2 (17) · Melanoma (17) · Sleep Initiation and Maintenance Disorders (17) · Anxiety Disorders (15) · Insulin Resistance (15) · Premature Birth (15) · Depression (12) · Asthma (11) · Hyperandrogenism (11)
Exercise (23) · Progesterone (11) · Blood Specimen Collection (9) · Continuous Glucose Monitoring (9) · Metformin (8) · Standard of Care (8) · Pancreas, Artificial (7) · Therapeutics (7) · Estradiol (6) · High-Intensity Interval Training (6) · Patient Education as Topic (6) · Surveys and Questionnaires (6) · sargramostim (6) · Capecitabine (5) · Cognitive Behavioral Therapy (5)
United States (746) · Bangladesh (21) · Canada (19) · Tanzania (9) · Italy (8) · Pakistan (8) · France (7) · India (7) · Kenya (6) · Zambia (6) · Peru (5) · Democratic Republic of the Congo (4) · Guatemala (4) · Australia (3) · Brazil (3)
Sue Brown, MD (10) · Christine Burt Solorzano, MD (9) · Yun M Shim, MD (8) · Craig L Slingluff, MD (6) · Daniel J Cox, PhD (6) · Marc Breton, PhD (6) · Jason Allen, PhD (5) · Lee M Ritterband, PhD (5) · Patrick Dillon, MD (5) · Zhenqi Liu, MD (5) · Boris Kovatchev, PhD (4) · Bruce Buckingham, MD (4) · Christopher R. McCartney, MD (4) · Craig L. Slingluff, MD (4) · David A Kaufman, MD (4)
PMID 23801798, PMID 24929429, PMID 22688340, PMID 33986124, PMID 37067353, PMID 40840991, PMID 42459945, PMID 10526739, PMID 10616858, PMID 106465, PMID 11202234, PMID 11595689, PMID 12091178, PMID 12135020, PMID 14581425, PMID 15004212, PMID 15079177, PMID 15220230, PMID 15248819, PMID 15302746, PMID 15343008, PMID 15349872, PMID 15758907, PMID 16012514, PMID 17659904, PMID 18477813, PMID 18607565, PMID 18809608, PMID 18978506, PMID 19251002, PMID 19251013, PMID 19459039, PMID 19556464, PMID 19581560, PMID 19596976, PMID 19660694, PMID 19935082, PMID 20038852, PMID 20185783, PMID 20472858, PMID 20561621, PMID 20588151, PMID 21042853, PMID 21168853, PMID 21173195, PMID 21445325, PMID 21481857, PMID 21570685, PMID 21838526, PMID 21864846
P50HD028934 (7), U54HD028934 (7), UC4DK108483 (7), R01DK085623 (5), R37CA248434 (3), KL2TR003016 (2), R01DK133148 (2), R01HD028160 (2), R01HD058671 (2), R01HD102060 (2), UL1TR003015 (2), 1DP3DK101055 (1), 1DP3DK101055-01 (1), 1OT2NS129366-01 (1), 1UG1EY036891 (1)