31 completed, 15 unknown, 1 active not recruiting, 1 recruiting. 17 Not applicable, 13 Phase 4, 9 Phase 3, 7 Phase 2, 2 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Safety and Efficacy of 5-HT3 Receptor Antagonist (Ramosetron) for the Treatment of Fecal Incontinence Ramosetron, Psyllium - Fecal Incontinence | Phase 2 / Phase 3 | Active not recruiting | Seoul National University Hospital | 147 | 2024-01-19 | 2026-10-27 |
| 5-HT3 Receptor Antagonist (Ramosetron) vs Loperamide for the Treatment of Low Anterior Resection Syndrome(RALARS) Ramosetron - LARS - Low Anterior Resection Syndrome | Not applicable | Recruiting | Seoul National University Hospital | 212 | 2023-03-27 | 2023-04-25 |
| Ramosetron on Late PONV (Postoperative Nausea and Vomiting) Ramosetron Hydrochloride - Postoperative Nausea and Vomiting, Breast Cancer Female | Phase 4 | Completed | Pusan National University Hospital | 144 | 2020-12-17 | 2022-04-19 |
| Ramosetron OD Tablet and Postdischarge Nausea and Vomiting Ramosetron - Day Surgery | Phase 4 | Unknown | Seoul National University Hospital | 138 | 2020-05-12 | 2021-12-22 |
| Effect of Ramosetron on Post-discharge Nausea and Vomiting Ramosetron, Normal saline - Hysteroscopy | Not applicable | Unknown | Seoul National University Bundang Hospital | 100 | 2018-03-01 | 2018-04-20 |
| Effect of Ramosetron on Heart Rate-corrected QT Interval During Robot-assisted Laparoscopic Prostatectomy With Steep Trendelenburg Position Ramosetron, Normal saline - Prostate Cancer | Not applicable | Completed | Yonsei University | 54 | 2017-08-01 | 2020-08-25 |
| Ramosetron Pre-treatment for PONV and QT Prolongation Ramosetron - PONV, Prolonged QTc Interval | Phase 4 | Completed | Konkuk University Medical Center | 64 | 2017-07-01 | 2018-03-09 |
| Clinical Trial Assessing 5-HT3 Receptor Antagonist (Ramosetron) for the Treatment of Anterior Resection Syndrome Ramosetron - Anterior Resection Syndrome | Early Phase 1 | Unknown | Seoul National University Hospital | 100 | 2016-08-01 | 2016-08-17 |
| Effect of Ramosetron on Bowel Motility After Gynecological Surgery Ramosetron, Normal saline - Postoperative Nausea and Vomiting | Phase 4 | Unknown | Kyunghee University Medical Center | 88 | 2016-07-01 | 2017-01-12 |
| Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis Automated recommendation at the start of the case, Automated notification at the start of surgery, Preoperative recommendations: by email - Postoperative Nausea and Vomiting | Not applicable | Completed | Vanderbilt University | 27034 | 2016-07-01 | 2019-03-07 |
| Analgesia Effects of Nalbuphine vs Sulfentanil Nalbuphine, Sufentanil, flurbiprofen axetil - C.Delivery; Surgery (Previous), Gynecological | Not applicable | Unknown | Fudan University | 80 | 2016-01-01 | 2015-11-13 |
| The Effects of Gabapentin and Ramosetron on Postoperative Nausea and Vomiting in Laparoscopic Gynecological Surgery Gabapentin, Ramosetron, Gabapentin and Ramosetron - Postoperative Nausea and Vomiting | Not applicable | Unknown | Hallym University Medical Center | 120 | 2015-11-01 | 2015-11-30 |
| Special Drug Use Surveillance of Irribow in Female Patients Ramosetron - Diarrhea-predominant Irritable Bowel Syndrome | Completed | Astellas Pharma Inc | 793 | 2015-10-01 | 2024-10-21 | |
| Therapeutic Efficacy of Ramosetron for Treatment of Established PONV After Laparoscopic Surgery Ondansetron, Ramosetron - Abdominal Mass | Not applicable | Completed | Yonsei University | 80 | 2015-09-07 | 2019-02-12 |
| Ramosetron, Aprepitant, and Dexamethasone Versus Palonosetron, Aprepitant, and Dexamethasone ramosetron, aprepitant, dexamethasone, palonosetron, aprepitant, dexamethasone - Cancer, Tumors | Phase 4 | Completed | Kangdong Sacred Heart Hospital | 292 | 2015-08-19 | 2018-05-11 |
| Post-operative Nausea Vomiting in Laparoscopic Cholecystectomy ramosetron, ondansetron, dexamethasone - Postoperative Nausea and Vomiting | Phase 4 | Unknown | Government Medical College, Haldwani | 100 | 2015-07-01 | 2016-06-17 |
| Comparative Effect Study Between Distal-proximal Point Association and Local Distribution Point Association in Chemotherapy-induced Nausea and Vomiting only antiemetic (Ramosetron, Tropisetron and dexamethasone), Matching points ST36+CV12 plus antiemetic drug, Matching points PC6+CV12 plus antiemetic drug - Chemotherapy-induced Nausea and Vomiting | Not applicable | Unknown | Tianjin University of Traditional Chinese Medicine | 240 | 2015-06-01 | 2015-06-23 |
| Comparison of Palonosetron and Ramosetron for Preventing Patient-controlled Analgesia Related Nausea and Vomiting Following Spine Surgery; Association With ABCB1 Polymorphism Ramosetron, Palonosetron - Postoperative Nausea and Vomiting | Phase 4 | Completed | Yonsei University | 300 | 2014-09-22 | 2017-10-27 |
| Efficacy Study of Ramosetron in the Setting of Hematopoietic Stem Cell Transplantation ramosetron - Hematologic Malignancies | Phase 2 | Unknown | The Catholic University of Korea | 65 | 2014-08-01 | 2014-12-08 |
| Anti Emetic Efficacy of Combination of Ramosetron and Premixture of Naloxone With Patient-controlled Analgesia Ramosetron, Naloxone, saline - Postoperative Nausea and Vomiting | Not applicable | Completed | Kyungpook National University Hospital | 90 | 2014-07-01 | 2016-02-22 |
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Postoperative Nausea and Vomiting (17) · Vomiting (12) · Irritable Bowel Syndrome (6) · Nausea (6) · Diarrhea (5) · Colonic Diseases (3) · Neoplasms (3) · Hypotension (2) · Adenomyosis (1) · Agnosia (1) · Colonic Neoplasms (1) · Fecal Incontinence (1) · Fractures, Bone (1) · Hematologic Neoplasms (1) · Low Anterior Resection Syndrome (1)
Astellas Pharma Inc (11) · Seoul National University Hospital (10) · Yonsei University (7) · Hallym University Medical Center (3) · Kyunghee University Medical Center (2) · Kyungpook National University Hospital (2) · Seoul National University Bundang Hospital (2) · Chonnam National University Hospital (1) · Fudan University (1) · Government Medical College, Haldwani (1) · Incheon St.Mary's Hospital (1) · Kangdong Sacred Heart Hospital (1) · Konkuk University Medical Center (1) · National Health Insurance Service Ilsan Hospital (1) · Pusan National University Hospital (1)
South Korea (27) · Japan (9) · Bulgaria (1) · China (1) · Czechia (1) · Estonia (1) · Germany (1) · India (1) · Lithuania (1) · Poland (1) · Russia (1) · Taiwan (1) · Ukraine (1) · United States (1)
Chanyeong Heo, Ph.D. (1) · F. Verbeeck (1) · Hyo Jung Kim, M.D. (1) · Hyun-Jung Shin, MD., PhD. (1) · Jin-Hyoung Kang, Ph.D (1) · Jonathan P Wanderer, MD, MPhil (1) · Jung Hye Kwon, PhD (1) · Ka Young Rhee, MD,PhD (1) · Mi Kyeong Kim (1) · Mi Kyeong Kim, M.D., Ph.D. (1) · Rumi Shin, MD, PhD (1) · Sang-Hee Cho, M.D.Ph.D. (1) · Sangwon Shin, M.D. (1)
PMID 27488394, PMID 21856001, PMID 25439413, PMID 25485883, PMID 26551550, PMID 26800997, PMID 27821107, PMID 28205278, PMID 28293280, PMID 28331539, PMID 28525981, PMID 31538078, PMID 33982068, PMID 34614204, PMID 35546414