Postoperative Cognitive Dysfunction (POCD): Clinical Trials

13 trials for Postoperative Cognitive Dysfunction (POCD), newest first

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7 not yet recruiting, 4 completed, 2 recruiting. 5 Not applicable.

By phase and status

PhaseTrialsStatus
Not applicable5Completed 3, Not yet recruiting 2

Follow Postoperative Cognitive Dysfunction (POCD): new trials by email Literature Review of Postoperative Cognitive Dysfunction (POCD) trials Research Report on Postoperative Cognitive Dysfunction (POCD)

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Cerebral Oximetry During Awake Carotid Endarterectomy
Masked continuous cerebral oximetry, Standardised awake neurological test, Serial cognitive assessment - Carotid Stenosis, Carotid Artery Diseases
Not yet recruitingNguyen Toan Thang1502027-01-012026-09-11
PCO₂ Gap and Lactate as Predictors of POCD After Cardiac Surgery
Postoperative Cognitive Dysfunction (POCD), Cardiac Surgery
Not yet recruitingAin Shams University1852026-12-012026-09-25
Awareness Neuraxial Versus General Anesthesia in Frail Patients Undergoing Laparoscopic or Robotic Abdominopelvic Surgery.
Neuraxial anesthesia, General Anesthesia, avoidance of GABAergic-drugs strategy - Fraily, Abdominal Surgery
Not applicableNot yet recruitingEnte Ospedaliero Ospedali Galliera1002026-09-012026-03-20
Prospective Neuropsychological Evaluation of the Implementation of a Heart Valve Unit (HVU-NEURO)
Aortic Valve Stenosis, Postoperative Cognitive Dysfunction (POCD)
Not yet recruitingHeart and Brain Research Group, Germany5002026-05-252026-06-04
Cohort Study of Postoperative Cognitive Dysfunction After Off-Pump Coronary Artery Bypass Grafting
Off-Pump Coronary Artery Bypass Grafting - Postoperative Cognitive Dysfunction (POCD)
Not yet recruitingBeijing Anzhen Hospital6002026-05-242026-06-11
Early Cognitive Changes After Same-day Discharge Hip and Knee Arthroplasty
Postoperative Cognitive Dysfunction (POCD), Cognitive Change
RecruitingOdense University Hospital482026-05-182026-06-22
Value of the Time-Weighted Average (TWA) of Mean Arterial Pressure (MAP) and Cerebral Oximetry (rSO₂) as Predictors of Postoperative Tissue Perfusion Impairment in Patients Undergoing Cardiac Surgery
Continuous intraoperative monitoring of MAP and rSO₂; observational study with no therapeutic intervention. - Delirium - Postoperative, Postoperative Cognitive Dysfunction (POCD)
Not yet recruitingHospital Universitari Vall d'Hebron Research Institute1202026-05-012026-04-03
Prediction Model for Postoperative Cognitive Dysfunction in Elderly Cardiac Patients: A Special Disease Cohort Study
Postoperative Cognitive Dysfunction (POCD), Cardiac Diseases Requiring Surgery
RecruitingShanghai Geriatric Medical Center6342026-03-032026-03-19
Effect of Perioperative IV Ibuprofen on Cerebral Oxygenation and Postoperative Cognition During One-Lung Ventilation
ibuprofen - Postoperative Delirium, Cerebral Oxygen Saturation
Not applicableNot yet recruitingOndokuz Mayıs University542026-02-152026-02-10
Target-Controlled Infusion and Postoperative Neurocognitive Outcomes in Geriatric Patients
Postoperative Cognitive Dysfunction (POCD), Neurocognitive Function
CompletedNamigar Turgut502025-05-052025-12-31
Comparison of Desflurane, Sevoflurane, and Total Intravenous Anesthesia in Ear Surgery Under Controlled Hypotension
Desflurane, Sevoflurane, Remifentanil - Postoperative Cognitive Dysfunction (POCD), Controlled Hypotension for Nasal Surgeries
Not applicableCompletedDr. Lutfi Kirdar Kartal Training and Research Hospital692023-12-012026-08-28
Intravenous Anesthesıa and Cognıtıve Functıon ın Spınal Surgery
Manual Controlled Infusion (MCI) of Propofol, Target Controlled Infusion (TCI) of Propofol - Postoperative Cognitive Dysfunction (POCD)
Not applicableCompletedBursa Yuksek Ihtisas Training and Research Hospital1282023-09-222026-11-02
Recovery After Upper Extrimety Surgery
BIS-Guided General Anesthesia, Clinically Guided General Anesthesia - Postoperative Delirium, Postoperative Recovery in Elderly Patients
Not applicableCompletedRegion Örebro County1122015-01-232026-07-20

Narrower conditions

Postoperative Cognitive Complications (13)  ·  Emergence Delirium (6)  ·  Agnosia (1)  ·  Aortic Valve Stenosis (1)  ·  Brain Ischemia (1)  ·  Carotid Artery Diseases (1)  ·  Carotid Stenosis (1)  ·  Frailty (1)  ·  Neurocognitive Disorders (1)

Broader conditions

Cognition Disorders (13)  ·  Cognitive Dysfunction (13)  ·  Mental Disorders (13)  ·  Pathologic Processes (13)  ·  Pathological Conditions, Signs and Symptoms (13)  ·  Postoperative Complications (13)  ·  Neurocognitive Disorders (12)  ·  Nervous System Diseases (7)  ·  Neurobehavioral Manifestations (7)  ·  Neurologic Manifestations (7)  ·  Signs and Symptoms (7)  ·  Confusion (6)  ·  Delirium (6)  ·  Cardiovascular Diseases (2)  ·  Aortic Valve Disease (1)

Interventions

Propofol (2)  ·  Anesthesia, General (1)  ·  Desflurane (1)  ·  Ibuprofen (1)  ·  Observation (1)  ·  Remifentanil (1)  ·  Respiration, Artificial (1)  ·  Sevoflurane (1)  ·  Transcobalamins (1)

Sponsors

Ain Shams University (1)  ·  Beijing Anzhen Hospital (1)  ·  Bursa Yuksek Ihtisas Training and Research Hospital (1)  ·  Dr. Lutfi Kirdar Kartal Training and Research Hospital (1)  ·  Ente Ospedaliero Ospedali Galliera (1)  ·  Heart and Brain Research Group, Germany (1)  ·  Hospital Universitari Vall d'Hebron Research Institute (1)  ·  Namigar Turgut (1)  ·  Nguyen Toan Thang (1)  ·  Odense University Hospital (1)  ·  Ondokuz Mayıs University (1)  ·  Region Örebro County (1)  ·  Shanghai Geriatric Medical Center (1)

Countries

Turkey (Türkiye) (3)  ·  China (2)  ·  Denmark (1)  ·  Italy (1)  ·  Sweden (1)  ·  Vietnam (1)

Top investigators

Marius Butz, Phd, M.Sc. (1)  ·  Martin Lindberg-Larsen, Professor (1)  ·  Matthias Renker, MD (1)  ·  Namigar Turgut, MD (1)  ·  Thang Toan Nguyen, MD, PhD (1)  ·  Wenjun Liu, PhD (1)  ·  Zekeriya Ervatan, MD (1)

Results publications

PMID 20601860, PMID 23027226, PMID 24410107, PMID 28299175

NIH funding

2014 (1)