18 completed, 18 recruiting, 8 not yet recruiting, 4 terminated. 36 Not applicable, 4 Phase 2, 3 Phase 3, 2 Phase 4, 1 Phase 1.
Follow Post-traumatic Stress Disorder (PTSD): new trials by email Literature Review of Post-traumatic Stress Disorder (PTSD) trials Research Report on Post-traumatic Stress Disorder (PTSD)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sleep Disturbances in Children and Adolescents With Post-traumatic Stress Disorder (PTSD): a Randomized Double-blind Placebo-controlled Trial to Investigate the Efficacy of Pediatric Prolonged-release Melatonin pediatric, prolonged released melatonin, Placebo - Post-traumatic Stress Disorder (PTSD), Current Significant Sleep Disturbances | Phase 3 | Not yet recruiting | University Hospital, Strasbourg, France | 120 | 2027-01-01 | 2026-02-18 |
| Transforming Trauma Care Trauma Resilience and Recovery Program Portal 2.0 (TRRP 2.0) - Post-Traumatic Stress Disorder (PTSD), Depression | Not applicable | Not yet recruiting | Medical University of South Carolina | 300 | 2026-12-01 | 2026-09-21 |
| Eye Movement Intervention With Different Memory Reactivation Procedures for Intrusive Traumatic Memories Unconscious Trauma Reactivation plus Eye Movements, Active Trauma Memory Reactivation plus Eye Movements, Neutral Memory Reactivation plus Eye Movements - Post-traumatic Stress Disorder (PTSD), Intrusive Memories of Traumatic Event(s) | Not applicable | Recruiting | Shaanxi Normal University | 117 | 2026-10-30 | 2026-10-15 |
| Discontinuing Psychotropic Medication Before Psychotherapy for PTSD Post-traumatic Stress Disorder (PTSD) | Not yet recruiting | Academic Centre for Dentistry in Amsterdam | 100 | 2026-09-01 | 2026-09-03 | |
| Prognosis of Epilepsy With Post-traumatic Stress Disorder and Surgery Baseline PTSD status, Psychiatric questionnaires - Epilepsies, Focal, Drug Restistant Epilepsie | Not yet recruiting | Assistance Publique Hopitaux De Marseille | 42 | 2026-09-01 | 2026-07-22 | |
| Grappling With Trauma: Brazilian Jiu-Jitsu for First Responders Brazilian Jiu-Jitsu Program - Post-traumatic Stress Disorder (PTSD), Trauma and Stress Related Disorders | Not applicable | Recruiting | Sam Houston State University | 8 | 2026-08-15 | 2026-08-27 |
| PTSD Risk Prediction Model for EICU Survivors Post-traumatic Stress Disorder (PTSD) | Not yet recruiting | Sir Run Run Shaw Hospital | 800 | 2026-08-15 | 2026-08-05 | |
| A Digital Cognitive Intervention for Intrusive Memories After Trauma Pre-selected Trauma-related Cue Images with Eye Movement, Patient-provided Trauma-related Cue Images with Eye Movement, Neutral Images with Eye Movement - Post-Traumatic Stress Disorder (PTSD), Intrusive Memories of Traumatic Event(s) | Not applicable | Recruiting | Zhu Zijian | 123 | 2026-06-10 | 2026-09-02 |
| The Efficacy and Safety of Temporal Interference Stimulation in the Treatment of Post-Traumatic Stress Disorder TI stimulation device (nerviox-1000） - Post-traumatic Stress Disorder (PTSD) | Not applicable | Recruiting | Shanghai Mental Health Center | 5 | 2026-06-08 | 2026-06-12 |
| Tetris Intervention Following Subliminal Reactivation for Intrusive Memories Subliminal Reactivation Followed by Visuospatial Interference, Computer-based Visuospatial Task (Tetris) - Post-traumatic Stress Disorder (PTSD), Intrusive Memories of Traumatic Event(s) | Not applicable | Recruiting | Shaanxi Normal University | 106 | 2026-04-10 | 2026-09-02 |
| Effect of Psilocybin and Structured Integrated Reframing Therapy on Gut-Brain Axis Biomarkers and Depression in Major Depressive Disorder Psilocybin, Structured Integrated Reframing Therapy (SIRT), Selective Serotonin Reuptake Inhibitor (SSRI) - Major Depressive Disorder, Post-Traumatic Stress Disorder (PTSD) | Phase 3 | Recruiting | Khyber Medical University Peshawar | 60 | 2026-04-01 | 2026-07-14 |
| Two-Year Follow-up Study on Children Exposed to Trauma Post-traumatic Stress Disorder (PTSD), Complex Post-Traumatic Stress Disorder (CPTSD) | Active not recruiting | Istanbul University | 136 | 2026-03-15 | 2026-07-13 | |
| Non-invasive Vagus Nerve Stimulation (nVNS) for Post-Traumatic Stress Disorder (PTSD) non-invasive vagus nerve stimulation - PTSD, Post Traumatic Stress Disorder PTSD | Not applicable | Recruiting | Acacia Clinics | 40 | 2026-03-02 | 2026-10-08 |
| Blended Trauma-Focused Cognitive Behavioral Therapy With Compassion Blended Trauma-Focused Cognitive Behavioral Therapy with Compassion (bTF-CBT-C), Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) - Post-traumatic Stress Disorder (PTSD) | Not applicable | Recruiting | Umeå University | 40 | 2026-02-23 | 2026-02-27 |
| Developing and Testing Innovative Care Pathways for Screening and Treatment of OUD/PTSD in Jails Cognitive Processing Therapy (CPT), Written Exposure Therapy (WET) - Post-traumatic Stress Disorder (PTSD), Post-traumatic Stress Symptoms | Not applicable | Enrolling by invitation | University of Arkansas | 338 | 2026-01-20 | 2026-06-18 |
| Accelerated Neuromodulation for Concurrent Post-Traumatic Stress Disorder (PTSD) & Chronic Pain in Veterans Transcranial magnetic stimulation - Chronic Pain, Post-traumatic Stress Disorder (PTSD) | Phase 4 | Not yet recruiting | Legion Veterans Village Research Foundation | 30 | 2026-01-01 | 2025-11-18 |
| A Computer Game for Postpartum Mental Health After Emergency Cesarean Birth implementation of a brief computer-based intervention "Tetris" - Post-traumatic Stress Disorder (PTSD), Postpartum Mental Health | Not applicable | Enrolling by invitation | Kyoto University, Graduate School of Medicine | 120 | 2025-12-13 | 2025-12-18 |
| EMDR Integrative Group Protocol and Individual Treatment for Patients With Cancer: A Pilot Study EMDR-IGTP-OTS - Thyroid Neoplasms, Neoplasm | Not applicable | Recruiting | Università Cattolica di Milano | 25 | 2025-12-05 | 2026-03-04 |
| Early Intervention After Traumatic Exposure in Children and Adolescents CFTSI (Child and Family Traumatic Stress Intervention), non-specific psychological support therapy - Post-traumatic Stress Disorder (PTSD) | Not applicable | Not yet recruiting | University Hospital, Montpellier | 140 | 2025-12-01 | 2025-10-03 |
| Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients Ketamine, standard general anesthesia - Orthopedic Trauma Surgery Patients, Postoperative Pain | Phase 4 | Recruiting | Texas Tech University Health Sciences Center | 90 | 2025-11-06 | 2026-03-24 |
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Stress Disorders, Post-Traumatic (57) · Wounds and Injuries (9) · Depression (8) · Anxiety Disorders (6) · Alcoholism (3) · Depressive Disorder, Major (3) · Aggression (2) · Brain Injuries, Traumatic (2) · Combat Disorders (2) · Emotional Regulation (2) · Mental Disorders (2) · Substance-Related Disorders (2) · Trauma and Stressor Related Disorders (2) · Alcohol-Related Disorders (1) · Autonomic Nervous System Diseases (1)
Stress Disorders, Traumatic (57) · Mental Disorders (55) · Trauma and Stressor Related Disorders (55) · Behavior (14) · Behavioral Symptoms (12) · Chemically-Induced Disorders (5) · Nervous System Diseases (5) · Pathological Conditions, Signs and Symptoms (5) · Brain Diseases (4) · Central Nervous System Diseases (4) · Mood Disorders (4) · Social Behavior (4) · Craniocerebral Trauma (3) · Depressive Disorder (3) · Pathologic Processes (3)
Magnetic Resonance Spectroscopy (3) · Eye Movements (2) · Ketamine (2) · Transcranial Magnetic Stimulation (2) · Cognitive Behavioral Therapy (1) · Cyclic AMP (1) · Dialectical Behavior Therapy (1) · Ecological Momentary Assessment (1) · Eye Movement Desensitization Reprocessing (1) · Interviews as Topic (1) · Low-Level Light Therapy (1) · Mental Status and Dementia Tests (1) · Oxytocin (1) · Prazosin (1) · Progesterone (1)
VA Office of Research and Development (5) · Istanbul University (3) · NYU Langone Health (3) · Yale University (3) · Assistance Publique Hopitaux De Marseille (2) · Shaanxi Normal University (2) · University Hospital, Strasbourg, France (2) · University of Konstanz (2) · Acacia Clinics (1) · Academic Centre for Dentistry in Amsterdam (1) · Assistance Publique - Hôpitaux de Paris (1) · Direction Centrale du Service de Santé des Armées (1) · Dokuz Eylul University (1) · Fisher and Paykel Healthcare (1) · GIFT University (1)
United States (22) · Turkey (Türkiye) (7) · China (5) · France (5) · Canada (2) · Greece (2) · Israel (2) · Pakistan (2) · Burundi (1) · Italy (1) · Japan (1) · Nepal (1) · Netherlands (1) · Rwanda (1) · South Africa (1)
Charles Marmar, MD (2) · Aaron B Holley, MD (1) · Abdurrahman C Orengul, Associate Professor (1) · Abdurrahman Cahid Orengul, Associate Professor, MD (1) · Adar Shani (1) · Alisan B Yasar, MD AssocProf (1) · Arun K Jha, FRCPsych (1) · Chi-Sing Li, Ph.D. (1) · Dr Inayat Shah, PhD* (1) · Dr Omer Malik, PhD (1) · Elizabeth Ralevski, Ph.D. (1)
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I01CX002762 (1), I21RX001768 (1), R33DA059947 (1)