17 completed, 13 unknown, 4 terminated, 1 active not recruiting. 35 Phase 3, 9 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 35 | Completed 17, Unknown 13, Terminated 4, Active not recruiting 1 |
| Phase 2 | 9 | Unknown 5, Completed 3, Terminated 1 |
Follow Pleural Diseases: new trials by email Literature Review of Pleural Diseases trials Research Report on Pleural Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Erector Spinae Plane Block With Bupivacaine for Medical Thoracoscopy Bupivacaine injection, Placebo, Monitored Anesthesia Care - Pleural Disease, Postoperative Pain | Phase 3 | Terminated | Icahn School of Medicine at Mount Sinai | 33 | 2024-03-28 | 2025-05-01 |
| A Phase Ⅲ Clinical Study of Combined Cisplatin Versus Placebo Combined With Intracavitary Cisplatin Injection in the Treatment of Malignant Pleural Effusions ENDOSTAR，cisplatin, Placebo , cisplatin - Malignant Pleural Effusion | Phase 3 | Active not recruiting | Jiangsu Simcere Pharmaceutical Co., Ltd. | 290 | 2021-07-28 | 2026-01-02 |
| Reactor Thoracostomy Reactor Device, Tube thoracostomy - Pneumothorax, Hemothorax | Phase 3 | Unknown | Crozer-Keystone Health System | 54 | 2019-01-01 | 2018-11-08 |
| Use of Vasopressin Following the Fontan Operation Vasopressin, Normal Saline - Pleural Effusion, Single-ventricle | Phase 2 / Phase 3 | Completed | Wake Forest University Health Sciences | 12 | 2016-12-01 | 2024-10-24 |
| Efficacy of Iodopovidone Versus Talc in Palliative Malignant Pleural Effusion Iodopovidone solution, Talc - Malignant Pleural Effusion | Phase 3 | Completed | Chiang Mai University | 60 | 2015-11-01 | 2020-01-23 |
| Comparing 14 F Pigtail Catheter to Traditional 28-32F Chest Tube in the Management of Traumatic Hemothorax and Hemopneumothorax Pigtail catheter - Traumatic Hemothorax | Phase 3 | Unknown | Narong Kulvatunyou | 40 | 2015-09-01 | 2015-09-17 |
| Effect of Dissecting of The Inferior Pulmonary Ligament on Postoperative Pulmonary Reexpansion and Recurrence DIPL, WR, thoracoscopic surgery - Pneumothorax | Phase 3 | Unknown | Chinese Medical Association | 260 | 2015-06-01 | 2015-10-16 |
| Comparison of Intrapleural Urokinase and Video-Assisted Thorascopic Surgery in the Treatment of Parapneumonic Pleural Effusion in Children insertion of a chest drain with urokinase instillation, primary video-assisted thorascopic surgery - Empyema, Pleural | Phase 3 | Unknown | Queen Fabiola Children's University Hospital | 40 | 2015-02-01 | 2018-07-05 |
| Absorbable Mesh Pleurodesis in Thoracoscopic Treatment of Spontaneous Pneumothorax Thoracoscopic bullectomy and pleural abrasion, Mesh coverage of the staple line - Spontaneous Pneumothorax, Surgery | Phase 2 / Phase 3 | Unknown | National Taiwan University Hospital | 204 | 2013-05-01 | 2015-07-08 |
| Intrapleural DNase and Tissue Plasminogen Activator in Pediatric Empyema (DTPA Trial) TPA (Tissue Plasminogen Activator), DNase, Placebo - Pleural Empyema | Phase 3 | Completed | The Hospital for Sick Children | 97 | 2012-12-01 | 2020-04-14 |
| KatGuide Method Versus Conventional Method at Insertion of Chest Tube KatGuide versus conventional method (forceps), Chest tube insertion - Pneumothorax, Hydrothorax | Phase 3 | Completed | Niels Katballe | 109 | 2012-04-01 | 2014-08-21 |
| COlchicine for Prevention of the Post-pericardiotomy Syndrome and Post-operative Atrial Fibrillation (COPPS-2 Trial) Colchicine, Placebo - Cardiac Surgery, Post-pericardiotomy Syndrome | Phase 3 | Unknown | Maria Vittoria Hospital | 360 | 2012-03-01 | 2014-07-01 |
| Cryobiopsy or Forceps Biopsy During Semirigid Thoracoscopy: a Comparative Study cryobiopsy (Autoclavable cryoprobe 20416-032 (ERBE, Germany) Flexible FB-55CD-1 Olympus forceps - Pleural Effusion, Pleural Diseases | Phase 2 / Phase 3 | Completed | The University Clinic of Pulmonary and Allergic Diseases Golnik | 40 | 2011-11-01 | 2015-09-10 |
| Use of Orotracheal Continuous Positive Airway Pressure (CPAP) in Newborns With Respiratory Failure OROTRACHEAL cpap WITH COMPENSATION BAG ( GREGORY CPAP) - Neonatal Respiratory Failure | Phase 2 / Phase 3 | Unknown | Hospital Angeles del Pedregal | 100 | 2011-06-01 | 2011-06-23 |
| Efficacy and Safety Study of Abnoba Viscum F 20mg in Malignant Pleural Effusion Patients Abnoba Viscum F 20mg - Malignant Pleural Effusion | Phase 3 | Completed | Abnoba Korea | 68 | 2011-01-01 | 2014-07-23 |
| Pigtail Catheter Versus Chest Tube in the Management of Traumatic Pneumothorax Pigtail catheter insertion (Cook), chest tube (28-French) - Traumatic Pneumothorax | Phase 3 | Unknown | University of Arizona | 38 | 2010-07-01 | 2012-02-23 |
| Intrapleural Bevacizumab and Cisplatin Therapy for Malignant Pleural Effusion Caused by Non-small Cell Lung Cancer Bevacizumab, Cisplatin - Malignant Pleural Effusion | Phase 3 | Completed | Chinese PLA General Hospital | 72 | 2009-08-01 | 2015-03-25 |
| Anemia Treatment for Advanced Non-Small Cell Lung Cancer (NSCLC) Patients Receiving Chemotherapy Darbepoetin alfa, Placebo - Non-Small Cell Lung Cancer, Anemia | Phase 3 | Terminated | Amgen | 2549 | 2009-07-17 | 2022-11-30 |
| A Prospective, Randomized Controlled Trial for a Rapid Pleurodesis Protocol for the Management of Pleural Effusions Thoracoscopy and Pleurx, Thoracoscopy - Malignant Pleural Effusions | Phase 3 | Completed | Singapore General Hospital | 120 | 2008-09-01 | 2017-02-10 |
| Chest Tube Drainage or Thoracoscopic Surgery for Failed Aspiration of Spontaneous Pneumothorax Video-assisted thoracoscopic surgery, chest tube drainage - Pneumothorax | Phase 2 / Phase 3 | Unknown | National Taiwan University Hospital | 60 | 2008-04-01 | 2012-12-17 |
Showing 20 of 35. Sign in to see all of them.
Pneumothorax (14) · Pleural Effusion, Malignant (10) · Pleural Effusion (7) · Empyema, Pleural (4) · Neoplasm Metastasis (4) · Hemothorax (3) · cyclopia sequence (3) · Carcinoma, Non-Small-Cell Lung (2) · Neoplasms (2) · Wounds and Injuries (2) · Agnosia (1) · Anemia (1) · Atrial Fibrillation (1) · Chylothorax (1)
Respiratory Tract Diseases (35) · Pathologic Processes (15) · Pathological Conditions, Signs and Symptoms (15) · Neoplasms by Site (10) · Pleural Neoplasms (10) · Respiratory Tract Neoplasms (10) · Thoracic Neoplasms (10) · Neoplasms (9) · Pleural Effusion (9) · Infections (5) · Inflammation (5) · Suppuration (5) · Empyema (4) · Hemorrhage (4)
Talc (5) · Saline Solution (3) · Thoracoscopy (3) · Cisplatin (2) · dornase alfa (2) · Arginine (1) · Arginine Vasopressin (1) · Bevacizumab (1) · Bleomycin (1) · Bupivacaine (1) · Cefazolin (1) · Chest Tubes (1) · Clindamycin (1) · Colchicine (1) · Darbepoetin alfa (1)
National Taiwan University Hospital (5) · Alliance for Clinical Trials in Oncology (2) · Abnoba Korea (1) · Aleš Rozman (1) · Amgen (1) · Angiotech Pharmaceuticals (1) · Azienda Ospedaliera di Padova (1) · Chiang Mai University (1) · Chinese Medical Association (1) · Chinese PLA General Hospital (1) · Colombian Neonatal Research Network (1) · Crozer-Keystone Health System (1) · Eastern Cooperative Oncology Group (1) · Hospital Angeles del Pedregal (1) · Icahn School of Medicine at Mount Sinai (1)
United States (9) · Taiwan (6) · China (4) · Italy (4) · Canada (3) · Slovenia (3) · South Korea (3) · Belgium (2) · Greece (2) · Switzerland (2) · United Kingdom (2) · Argentina (1) · Austria (1) · Brazil (1) · Bulgaria (1)
Yung-Chie Lee, MD, PhD (4) · Jin-Shing Chen, MD, PhD (2) · Ales Rozman, MD (1) · Apichat Tantraworasin (1) · Devanand Anantham, FCCP (1) · Eyal Cohen, MD, MSc (1) · Friedemann Schad, MD (1) · Giorgio Stefanutti, MD (1) · Hyo-Chun Yoon, MD (1) · Jamie Penk, MD (1) · Jemi Olak, MD (1) · Jian Cui, director (1) · Jin Li, Doctor (1) · John C. Ruckdeschel, MD (1) · Kook Joo Na, MD (1)
PMID 15764775, PMID 24375295, PMID 14973997, PMID 16478853, PMID 17567670, PMID 19117872, PMID 22323011, PMID 23188235, PMID 23418922, PMID 23489754, PMID 23816016, PMID 24942631, PMID 25172965, PMID 26409714, PMID 28646887, PMID 32011642, PMID 33279544, PMID 33415448, PMID 40099426
U10CA031946 (1), U10CA076001 (1)