6 completed, 2 recruiting, 1 suspended, 1 terminated. 4 Not applicable, 3 Phase 2, 2 Phase 1, 1 Early Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 2, Recruiting 1, Unknown 1 |
| Phase 2 | 3 | Completed 2, Suspended 1 |
| Phase 1 | 2 | Completed 1, Suspended 1 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Chylothorax: new trials by email Literature Review of Chylothorax trials Research Report on Chylothorax
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Olive Oil Before Lung Cancer Surgery to Prevent Chylothorax Extra-Virgin Olive Oil - Lung Cancer, Chylothorax | Not applicable | Recruiting | Fudan University | 1036 | 2026-03-15 | 2026-09-08 |
| European Registry Study on Lymphatic Interventions Lymphatic intervention - Lymphatic Disorders, Plastic Bronchitis | Recruiting | Copenhagen University Hospital, Rigshospitalet | 500 | 2026-02-01 | 2026-01-21 | |
| Propranolol Treatment for Postoperative Chylothorax Propranolol Hydrochloride, Placebo - Postoperative Chylothorax, Congenital Heart Disease | Phase 1 / Phase 2 | Suspended | June Wu | 50 | 2025-09-09 | 2026-05-15 |
| Octreotide Improves Human Lymphatic Fluid Transport a Translational Trial Octreotide infusion, Saline infusion - Lymphatic Diseases, Chylothorax | Early Phase 1 | Completed | Copenhagen University Hospital, Rigshospitalet | 16 | 2020-07-01 | 2023-03-30 |
| Suturing With U-Technique Versus Un-Reapproximated Wound Edges During Removal of Closed Thoracostomy Tube Drain Closure of chest tube wound - Pleural Effusion, Pneumothorax | Not applicable | Unknown | University of Ibadan | 142 | 2020-01-02 | 2020-02-25 |
| FLOTOR Pilot Study Indocyanine Green - Chylothorax, Esophageal Cancer | Phase 1 / Phase 2 | Completed | Oxford University Hospitals NHS Trust | 21 | 2017-12-20 | 2018-11-19 |
| Optimizing Growth in Infants Receiving Modified Fat Breast Milk for the Treatment of Chylothorax Target Fortification, Higher Initial Concentration, Portagen Formula - Chylothorax | Not applicable | Completed | The Hospital for Sick Children | 24 | 2015-10-01 | 2021-09-08 |
| KatGuide Method Versus Conventional Method at Insertion of Chest Tube KatGuide versus conventional method (forceps), Chest tube insertion - Pneumothorax, Hydrothorax | Phase 3 | Completed | Niels Katballe | 109 | 2012-04-01 | 2014-08-21 |
| Dietary Treatment of Infants With Chylothorax Fat-Modified Breast Milk, MCT formula - Chylothorax | Not applicable | Completed | The Hospital for Sick Children | 16 | 2008-01-01 | 2014-05-21 |
| Chylothorax Following Heart Surgery Chylothorax | Terminated | Children's Healthcare of Atlanta | 70 | 2005-05-01 | 2012-03-16 | |
| Treatment With Octreotide in Patients With Lymphangioleiomyomatosis Octreotide - Lymphangioleiomyomatosis, Lymphangiomyomas | Phase 2 | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 4 | 2000-06-01 | 2010-04-30 |
Empyema (2) · Lymphatic Diseases (2) · Pleural Effusion (2) · Pneumothorax (2) · Ascites (1) · Chylous Ascites (1) · Empyema, Pleural (1) · Esophageal Neoplasms (1) · Heart Defects, Congenital (1) · Hemothorax (1) · Hydrothorax (1) · Lung Neoplasms (1) · Lymphangioleiomyomatosis (1) · Lymphangiomyoma (1)
Respiratory Tract Diseases (11) · Pleural Diseases (10) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Digestive System Diseases (3) · Hemic and Lymphatic Diseases (3) · Neoplasms (3) · Congenital Abnormalities (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Gastrointestinal Diseases (2) · Infections (2) · Inflammation (2) · Neoplasms by Site (2) · Suppuration (2) · Cardiovascular Abnormalities (1)
2-Propanol (1) · Indocyanine Green (1) · Octreotide (1) · Propranolol (1) · Surgical Instruments (1)
Copenhagen University Hospital, Rigshospitalet (2) · The Hospital for Sick Children (2) · Children's Healthcare of Atlanta (1) · Fudan University (1) · June Wu (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · Niels Katballe (1) · Oxford University Hospitals NHS Trust (1) · University of Ibadan (1)
Denmark (3) · United States (3) · Canada (2) · China (1) · Nigeria (1) · United Kingdom (1)
Deborah L O'Connor, PhD RD (2) · Jennifer Russell, MD (2) · Brian Kogon, MD (1) · June Wu, MD (1) · Lateef A Baiyewu, MD,FWACS (1) · Michael Rahbek Schmidt, Ass. professor, PhD, DMSc (1) · Niels Katballe, MD, PhD (1) · Richard Gillies, MBChB (1) · Sara DiLauro, MSc(c) RD (1) · Sarah Kocel, MSc RD (1) · Thomas Barnes, MBChB (1) · Vibeke E Hjortdal, Professor (1)