5 completed, 2 unknown, 1 not yet recruiting, 1 terminated. 6 Phase 3, 1 Not applicable, 1 Phase 1, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 5, Withdrawn 1 |
| Not applicable | 1 | Not yet recruiting 1 |
| Phase 1 | 1 | Unknown 1 |
| Phase 2 | 1 | Unknown 1 |
| Phase 4 | 1 | Terminated 1 |
Follow Talc: new trials by email Literature Review of Talc trials Research Report on Talc
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Study to Assess Safety, Effectiveness and In-Use Tolerability of Saffron Extract Capsules for Improving Skin Health and Reducing Signs of Aging on Healthy Adult Male and Female Subjects. Standardized Saffron Extract (Crocus Sativus L) 10 mg Capsule, Placebo (capsules containing Maltodextrin, Calcium carbonate, Sunset yellow, Maize starch, Mg Stearate, Talc) - Wrinkles, Fine Lines | Not applicable | Not yet recruiting | NovoBliss Research Pvt Ltd | 50 | 2026-01-01 | 2026-01-07 |
| Randomized Controlled Trial of Talc Instillation In Addition To Daily Drainage Through a Tunneled Pleural Catheter to Improve Rates of Outpatient Pleurodesis in Patients With Malignant Pleural Effusion Talc - Malignant Pleural Effusion | Phase 4 | Terminated | Duke University | 4 | 2021-03-18 | 2023-09-28 |
| Dry Pleurodesis With Talcum and Afatinib is Used to Treat Patients With Non-Small Cell Lung Carcinoma Afatinib, Talcum powder - Non Small Cell Lung Cancer | Phase 1 | Unknown | Center Trials & Treatment Europe | 12 | 2019-03-05 | 2023-04-25 |
| Comparison of Progel Sealant to Standard of Care (SOC) for Patients Undergoing Decortication Progel Sealant, Talcum Powder, Pain Questionnaire - Lung Diseases, Mesothelioma | Phase 3 | Withdrawn | M.D. Anderson Cancer Center | 2015-12-01 | 2015-12-15 | |
| Efficacy of Iodopovidone Versus Talc in Palliative Malignant Pleural Effusion Iodopovidone solution, Talc - Malignant Pleural Effusion | Phase 3 | Completed | Chiang Mai University | 60 | 2015-11-01 | 2020-01-23 |
| Phase II Study of CG100649 for Primary Osteoarthritis in Male Subjects CG100649, Silicified microcrystalline cellulose + talc - Osteoarthritis, Knee, Osteoarthritis, Hip | Phase 2 | Unknown | CrystalGenomics, Inc. | 240 | 2007-10-01 | 2008-06-13 |
| Video-Assisted Surgery or Talc Pleurodesis in Treating Patients With Malignant Mesothelioma talc, therapeutic thoracoscopy, therapeutic videothoracoscopy - Malignant Mesothelioma, Metastatic Cancer | Phase 3 | Completed | Papworth Hospital NHS Foundation Trust | 196 | 2003-09-01 | 2013-06-28 |
| Standard Chest Tube Compared With a Small Catheter in Treating Malignant Pleural Effusion in Patients With Cancer talc, dyspnea management - Metastatic Cancer, Pulmonary Complications | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 67 | 2002-05-01 | 2016-07-04 |
| Bleomycin, Doxycycline, or Talc in Treating Patients With Malignant Pleural Effusions bleomycin sulfate, doxycycline, talc - Metastatic Cancer | Phase 3 | Completed | Eastern Cooperative Oncology Group | 480 | 1997-01-10 | 2023-06-22 |
| Talc in Treating Patients With Malignant Pleural Effusion talc, Talc - Metastatic Cancer | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 501 | 1994-12-01 | 2016-06-28 |
Pleural Effusion, Malignant (6) · Neoplasm Metastasis (4) · Carcinoma, Non-Small-Cell Lung (1) · Hyperpigmentation (1) · Lung Diseases (1) · Mesothelioma (1) · Mesothelioma, Malignant (1) · Osteoarthritis (1) · Osteoarthritis, Hip (1) · Osteoarthritis, Knee (1) · Solitary Fibrous Tumor, Pleural (1)
Alliance for Clinical Trials in Oncology (2) · Center Trials & Treatment Europe (1) · Chiang Mai University (1) · CrystalGenomics, Inc. (1) · Duke University (1) · Eastern Cooperative Oncology Group (1) · M.D. Anderson Cancer Center (1) · NovoBliss Research Pvt Ltd (1) · Papworth Hospital NHS Foundation Trust (1)
United States (3) · Canada (1) · Georgia (1) · Germany (1) · Thailand (1) · United Kingdom (1)
Apichat Tantraworasin (1) · Jemi Olak, MD (1) · John C. Ruckdeschel, MD (1) · Nayan Patel (1) · Randolph S. Marks, MD (1) · Reza J. Mehran, MD (1) · Robert Winter, MD (1) · Scott Shofer (1) · Todd Demmy, MD (1) · William K Schmidt, PhD (1)
U10CA031946 (1), U10CA076001 (1)