47 completed, 8 unknown, 5 recruiting, 1 active not recruiting. 33 Not applicable, 10 Phase 3, 5 Phase 4, 4 Phase 1, 4 Phase 2.
Follow Plaque: new trials by email Literature Review of Plaque trials Research Report on Plaque
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Evaluation of a Toothpaste for Dental Plaque Reduction and Prevention of Gum Problems 0.45% SnF HW with NaF (1450 F), 67% Bicarbonate with NaF (1400 F), Colgate Cavity Protection Toothpaste - Plaque, Dental Plaque | Phase 3 | Recruiting | Colgate Palmolive | 120 | 2026-07-20 | 2026-09-25 |
| Study to Investigate Toothpaste on Antibacterial Effects in the Different Regions of the Mouth stannous fluoride toothpaste, 0.76% Sodium Monofluorophosphate (Na MFP) toothpaste - Plaque, Gingivitis | Phase 3 | Completed | Colgate Palmolive | 95 | 2026-05-18 | 2026-09-24 |
| Clinical Study to Collect and Analyze Dental Plaque and Oral Health Measures in a Population With High Plaque/Low Gingivitis and High Plaque/High Gingivitis sodium monofluorophosphate toothpaste - Gingivitis, Plaque | Phase 4 | Recruiting | Colgate Palmolive | 100 | 2026-04-20 | 2026-05-29 |
| Comparison of the Effects of Oral Hygiene Regimens on Clinical, Immunomodulatory, and Microbial Outcomes and Oral Tolerance in People With Gingivitis Distilled Water, Marketed Comparator 1, Marketed Comparator 2 - Microbiome, Cytokines | Not applicable | Recruiting | Kenvue Brands LLC | 250 | 2026-02-26 | 2026-03-30 |
| Efficacy of a Stannous Fluoride Toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reducing Established Dental Plaque and Gingivitis. 0.454%Stannous fluoride toothpaste, 0.075% Cetylpyridinium Chloride (CPC) and 0.28% zinc lactatmouthwashe, 0.76% Sodium Monofluorophosphate (Na MFP) toothpaste - Plaque | Phase 3 | Completed | Colgate Palmolive | 134 | 2026-01-26 | 2026-05-22 |
| The Efficacy of a Battery Toothbrush in the Reduction of Established Plaque and Gingivitis Total Active Prevention Fresh Toothpaste + Colgate Total Active Prevention Battery Toothbrush, Colgate Great Regular + Total Active Prevention Battery Toothbrush, Colgate Great Regular + standard reference flat trim toothpaste - Plaque, Gingivitis | Phase 3 | Completed | Colgate Palmolive | 130 | 2025-10-14 | 2026-09-21 |
| Stannous Fluoride Toothpaste for Reduction and Treatment of Gingivitis Sodium Fluoride Dentifrice, Stannous Fluoride Toothpaste (SnF) - Gingival Inflammation, Plaque | Not applicable | Completed | Church & Dwight Company, Inc. | 133 | 2025-03-17 | 2026-06-10 |
| Intracoronary Cryotherapy Effect on Stabilization of Vulnerable Plaque in Patients With Stable Angina or ACS - A Traditional Feasibility Study Intracoronary Cryotherapy - Coronary Arterial Disease (CAD), Plaque | Not applicable | Recruiting | Cryotherapeutics SA | 30 | 2025-03-01 | 2026-04-06 |
| PCCT-Defined High-Risk Plaque and Future Coronary Events: The PREDICT Study Coronary Artery Disease, Plaque | Recruiting | Beijing Chao Yang Hospital | 500 | 2025-01-18 | 2026-09-16 | |
| Full-mouth Electronic Toothbrush vs. Conventional Electronic Toothbrush FMET - Toothbrush, Gingivitis | Not applicable | Completed | University of Minnesota | 94 | 2024-12-30 | 2025-12-17 |
| Recycling of Three Pressable Ceramics With Different Weight Percentage clinical measurements and evaluation - Plaque, Patient Satisfaction | Not applicable | Active not recruiting | Faculty of Dental Medicine for Girls | 15 | 2024-07-01 | 2024-08-28 |
| Effect of Probiotic Toothpaste and Regular Toothpaste on Plaque Levels of Orthodontic Patients Probiotic Toothpaste - Plaque | Not applicable | Completed | Kanza Tahir | 52 | 2024-06-04 | 2024-08-02 |
| The Clinical of Stannous Fluoride Toothpaste and a Newly Designed Toothbrush Compared to Colgate Cavity Protection Toothpaste and a Regular Toothbrush in Reducing Plaque and Gingivitis. Stannous fluoride toothpaste, Colgate Cavity Protection Toothpaste - Plaque, Gingivitis | Phase 3 | Completed | Colgate Palmolive | 95 | 2024-04-22 | 2026-03-19 |
| Efficacy and Safety Evaluation of Jet Floss EX After 8-week Application the test product (Jet Floss EX), the control product (interdental brush) - Bleeding on Probing, Plaque | Not applicable | Completed | Guang Dong Bixdo Health Technology Co.,Ltd | 72 | 2024-04-09 | 2024-12-05 |
| Clinical Research Study to Assess the Efficacy of Two Brushing Regimens in the Reduction of Established Dental Plaque and Gingivitis. manual Tooth Brush + Colgate Total TP (0.454% SnF, 1100 ppm F), manual toothbrush + Colgate dental cream - Gingivitis, Plaque | Phase 3 | Completed | Colgate Palmolive | 82 | 2024-01-22 | 2026-03-19 |
| Efficacy of Regular, Musical and Electric Toothbrushes in Plaque Removal in Children Regular Toothbrush, Musical toothbrush, Electric toothbrush - Children, Adult, Plaque | Not applicable | Completed | Jouf University | 111 | 2024-01-01 | 2024-08-07 |
| Multi-Media Parent-based Intervention to Promote Dental Hygiene Among Young Children: BeReady2Smile II Comparison Condition, BeReady2Smile video only, BeReady2Smile video and BeReady2Smile app completely self-guided - Plaque | Not applicable | Completed | Oregon Research Behavioral Intervention Strategies, Inc. | 228 | 2023-04-10 | 2025-10-08 |
| Regular Antibacterial Photodynamic Therapy on Oral Hygiene in the Elderly 24-hour Care Lumoral Treatment, Standard oral hygiene instructions - Inflamed Gums, Dryness Oral | Not applicable | Withdrawn | Koite Health Oy | 2023-01-01 | 2024-10-16 | |
| Evaluating the Performance and Safety of the Medical Device Plenhyage® in the Treatment of Dermal Tissue Defects Plenhyage - Cicatrix, Lipodystrophy | Not applicable | Unknown | I.R.A. Istituto Ricerche Applicate S.p.A. | 48 | 2022-03-30 | 2022-10-25 |
| Evaluating the Performance and Safety of the Medical Device Auralya® in the Treatment of Facial Dermal Tissue Defects Auralya - Cicatrix, Lipodystrophy | Not applicable | Unknown | I.R.A. Istituto Ricerche Applicate S.p.A. | 48 | 2022-03-21 | 2022-10-25 |
Showing 20 of 63. Sign in to see all of them.
Plaque, Amyloid (63) · Gingivitis (35) · Cicatrix (4) · Dental Plaque (4) · Gingival Hemorrhage (4) · Lipodystrophy (4) · Dental Calculus (3) · Hemorrhage (3) · Inflammation (3) · Angiofibroma (2) · Atherosclerosis (2) · Coronary Artery Disease (2) · Periodontitis (2) · Tuberous Sclerosis (2) · Xerostomia (2)
Pathological Conditions, Anatomical (63) · Pathological Conditions, Signs and Symptoms (63) · Stomatognathic Diseases (42) · Mouth Diseases (39) · Infections (37) · Periodontal Diseases (37) · Gingival Diseases (35) · Pathologic Processes (14) · Tooth Diseases (10) · Dental Deposits (7) · Metabolic Diseases (5) · Nutritional and Metabolic Diseases (5) · Skin Diseases (5) · Skin and Connective Tissue Diseases (5) · Cardiovascular Diseases (4)
Chlorhexidine (2) · Supersmile (2) · Toothpastes (2) · fluorophosphate (2) · hydrated silica gel-based toothpaste (2) · American Dental Association (1) · Atorvastatin (1) · Bicarbonates (1) · Cetylpyridinium (1) · Ethanol (1) · Glycyrrhiza glabra extract (1) · Listerine (1) · Meridol (1) · Oils, Volatile (1) · Propolis (1)
Colgate Palmolive (10) · Home Skinovations Ltd. (4) · I.R.A. Istituto Ricerche Applicate S.p.A. (4) · Procter and Gamble (4) · Johnson & Johnson Consumer Inc. (J&JCI) (3) · Church & Dwight Company, Inc. (2) · Johnson & Johnson Consumer and Personal Products Worldwide (2) · Nobelpharma (2) · University of California, Los Angeles (2) · Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (1) · BG Medicine, Inc (1) · Beijing Chao Yang Hospital (1) · Biofarma (1) · Cairo University (1) · Cryotherapeutics SA (1)
United States (20) · Canada (5) · Romania (4) · Brazil (3) · Italy (3) · Thailand (3) · United Kingdom (3) · China (2) · Egypt (2) · Japan (2) · Saudi Arabia (2) · Belgium (1) · Denmark (1) · Indonesia (1) · Malaysia (1)
Mihaela Fratila (4) · Chhaju Ram Goyal, DDS (2) · Terdphong Triratana (2) · Abdul Rashid Ismail, BDS (1) · Annahita Ghassemi (1) · Augusto R. Elias-Boneta, DMD.MSD (1) · Bennett T Amaechi, BDS, MS, PhD (1) · Carlos Collet, MD (1) · David R Smith, PhD (1) · Domenick T Zero, DDS, MS (1) · Dr Subhash Garg (1) · Erling Falk, MD, PhD (1) · Faculty Of Dentistry, Faculty (1) · Farid Ayad, B.D.S., D.D.S., MSC (1) · Gabriella John, MS (1)
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R44DE027001 (1)