30 completed, 3 unknown, 1 terminated. 30 Not applicable, 2 Phase 2, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 30 | Completed 26, Unknown 3, Terminated 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 3 | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intra Oral Appliance (IOA) Model Evaluating the Efficacy of Sensitive Toothpaste Negative Control Toothpaste, Active Comparator, Test toothpaste - Dental Caries | Not applicable | Completed | Church & Dwight Company, Inc. | 30 | 2025-04-15 | 2026-02-19 |
| Stannous Fluoride Toothpaste for Reduction and Treatment of Gingivitis Sodium Fluoride Dentifrice, Stannous Fluoride Toothpaste (SnF) - Gingival Inflammation, Plaque | Not applicable | Completed | Church & Dwight Company, Inc. | 133 | 2025-03-17 | 2026-06-10 |
| Dental Plaque Prevention Efficacy of a Stannous Fluoride Toothpaste Stannous Fluoride Toothpaste (SnF), Sodium Fluoride Dentifrice - Dental Plaque | Not applicable | Completed | Church & Dwight Company, Inc. | 91 | 2024-10-16 | 2026-02-19 |
| Intraoral Appliance (IOA) Model Evaluating the Efficacy of a Whitening Toothpaste Negative Control Toothpaste, Active Comparator, Test Toothpaste - Dental Caries | Not applicable | Completed | Church & Dwight Company, Inc. | 31 | 2024-10-08 | 2026-02-19 |
| Evaluation of a Stannous Fluoride Dentifrice for Control of Oral Malodor Sodium Fluoride Dentifrice, Stannous Fluoride Toothpaste (SnF) - Oral Malodor (Halitosis) | Not applicable | Completed | Church & Dwight Company, Inc. | 49 | 2024-09-09 | 2026-02-23 |
| Intra Oral Application (IOA) Testing Study of a Stannous Toothpaste Negative Control Treatment Slurry (Fluoride-Free), Active Comparator Fluoride Treatment (0.454% SnF), Test Fluoride Treatment (0.454% SnF) (Investigational Toothpaste) - Dental Caries | Not applicable | Completed | Church & Dwight Company, Inc. | 31 | 2024-08-12 | 2026-02-19 |
| Extrinsic Tooth Whitening Evaluation of a Whitening Toothpaste Whitening Test Dentifrice (Code 826), Control dentifrice (Code 378) - Stain Removal Efficacy | Not applicable | Completed | Church & Dwight Company, Inc. | 118 | 2024-08-08 | 2026-02-24 |
| Two Week Cumulative Extrinsic Stain Removal of a Battery-powered Toothbrush and a Manual Toothbrush Battery operated toothbrush, Manual toothbrush - Dental Devices, Home Care | Not applicable | Completed | Church & Dwight Company, Inc. | 102 | 2023-11-27 | 2024-03-05 |
| Single Brushing Plaque Removal Efficacy of a Battery-powered Toothbrush and a Manual Toothbrush Battery operated toothbrush, Manual toothbrush - Plaque, Dental | Not applicable | Completed | Church & Dwight Company, Inc. | 62 | 2023-11-13 | 2024-02-28 |
| Assess Efficacy and Safety of a Nasal Spray in Adults With Dry or Irritated Nose Sterimar Stop & Protect Irritation & Dryness - Dry Nose | Not applicable | Completed | Church & Dwight Company, Inc. | 70 | 2023-10-27 | 2024-11-20 |
| Pilot Study to Assess Performance and Safety of SULFEX 13081.22 Nasal Spray in Patients With Dry or Irritated Nose SULFEX 13081.22 - Dry Nose, Nose Irritation | Not applicable | Unknown | Church & Dwight Company, Inc. | 40 | 2022-09-02 | 2023-03-03 |
| Sterimar Allergic Rhinitis Seawater nasal spray - Allergic Rhinitis | Not applicable | Completed | Church & Dwight Company, Inc. | 59 | 2022-07-13 | 2022-10-19 |
| Synthetic Male Condom Slippage-Breakage Study Test Product, Control Product - Contraceptive, Sexually Transmitted Diseases | Not applicable | Completed | Church & Dwight Company, Inc. | 600 | 2022-06-10 | 2023-11-08 |
| A Nasal Spray for Relief of Nasal Congestion in Infants and Toddlers With Common Cold Blocked Nose Baby nasal spray, Standard of care - Nasal Congestion | Not applicable | Completed | Church & Dwight Company, Inc. | 220 | 2022-01-20 | 2023-10-26 |
| Two Seawater-based Formulations for Relief of Nasal Congestion in Paediatric Subjects IP1 - Stérimar BLOCKED NOSE Baby nasal spray, IP2 - Stérimar Stop & Protect Cold Baby + standard of care, Standard of Care - Common Cold, Nasal Congestion | Not applicable | Terminated | Church & Dwight Company, Inc. | 9 | 2021-11-25 | 2024-10-03 |
| Clinical Trial of Anusol Ointment for Symptom Relief in Patients With Haemorrhoids Anusol, Relief [Name], Placebo - Hemorrhoids | Phase 3 | Completed | Church & Dwight Company, Inc. | 66 | 2021-11-25 | 2022-08-15 |
| Assess the Effects of a Limosilactobacillus Supplement on Recurrence of UTI in Healthy Women During a 6-month Period Limosilactobacillus reuteri 3613, Placebo - Uncomplicated Symptomatic Urinary Tract Infections | Not applicable | Unknown | Church & Dwight Company, Inc. | 130 | 2021-05-07 | 2023-03-31 |
| Dental Plaque Removal Evaluation and Comparison of Kid's Battery-Operated Toothbrush and Manual Toothbrush Battery operated toothbrush, Manual toothbrush - Plaque, Dental | Not applicable | Completed | Church & Dwight Company, Inc. | 60 | 2020-11-23 | 2021-03-12 |
| Plaque Removal Efficacy of Four Dentifrices Following a Single Brushing Dentifrices - Plaque, Dental | Phase 2 | Completed | Church & Dwight Company, Inc. | 70 | 2020-11-16 | 2021-03-12 |
| A Study to Investigate the Safety and Efficacy of a Probiotic on Gastrointestinal Health in Healthy Adults Lactobacillus plantarum 276, Placebo - Gastrointestinal Health, Healthy | Not applicable | Unknown | Church & Dwight Company, Inc. | 50 | 2019-12-18 | 2020-01-10 |
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Edema (6) · Erythema (6) · Dental Plaque (5) · Dental Caries (3) · Gingivitis (3) · Nasal Obstruction (3) · Hemorrhage (2) · Plaque, Amyloid (2) · Common Cold (1) · Epistaxis (1) · Halitosis (1) · Hemorrhoids (1) · Rhinitis, Allergic (1) · Sexually Transmitted Diseases (1) · Sneezing (1)
Dentifrices (2) · Standard of Care (2) · Ascorbic Acid (1) · Benzocaine (1) · Cholecalciferol (1) · Control Groups (1) · Desiccation (1) · Lacteol (1) · Oxymetazoline (1) · Peruvian balsam (1) · Phenylephrine (1) · Probiotics (1) · Zinc Oxide (1) · bismuth oxide (1) · bismuth subgallate (1)
United States (21) · Canada (6) · Armenia (2) · Poland (2) · France (1) · Italy (1)
Annahita Ghassemi, PhD (7) · Annahita Ghassemi (3) · Anna Rynkiewicz, MD (1) · David Crowley, MD (1) · Jeffery L Milleman, DDS, MPA (1) · Jimmy Qaqish (1) · John Dosik, MD (1) · Lynne B Harrison, PhD (1) · Terri Walsh, MPH (1)