8 completed, 1 recruiting, 1 unknown. 10 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Completed 8, Recruiting 1, Unknown 1 |
Follow Plaque: new trials by email Literature Review of Plaque trials Research Report on Plaque
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Evaluation of a Toothpaste for Dental Plaque Reduction and Prevention of Gum Problems 0.45% SnF HW with NaF (1450 F), 67% Bicarbonate with NaF (1400 F), Colgate Cavity Protection Toothpaste - Plaque, Dental Plaque | Phase 3 | Recruiting | Colgate Palmolive | 120 | 2026-07-20 | 2026-09-25 |
| Study to Investigate Toothpaste on Antibacterial Effects in the Different Regions of the Mouth stannous fluoride toothpaste, 0.76% Sodium Monofluorophosphate (Na MFP) toothpaste - Plaque, Gingivitis | Phase 3 | Completed | Colgate Palmolive | 95 | 2026-05-18 | 2026-09-24 |
| Efficacy of a Stannous Fluoride Toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reducing Established Dental Plaque and Gingivitis. 0.454%Stannous fluoride toothpaste, 0.075% Cetylpyridinium Chloride (CPC) and 0.28% zinc lactatmouthwashe, 0.76% Sodium Monofluorophosphate (Na MFP) toothpaste - Plaque | Phase 3 | Completed | Colgate Palmolive | 134 | 2026-01-26 | 2026-05-22 |
| The Efficacy of a Battery Toothbrush in the Reduction of Established Plaque and Gingivitis Total Active Prevention Fresh Toothpaste + Colgate Total Active Prevention Battery Toothbrush, Colgate Great Regular + Total Active Prevention Battery Toothbrush, Colgate Great Regular + standard reference flat trim toothpaste - Plaque, Gingivitis | Phase 3 | Completed | Colgate Palmolive | 130 | 2025-10-14 | 2026-10-29 |
| The Clinical of Stannous Fluoride Toothpaste and a Newly Designed Toothbrush Compared to Colgate Cavity Protection Toothpaste and a Regular Toothbrush in Reducing Plaque and Gingivitis. Stannous fluoride toothpaste, Colgate Cavity Protection Toothpaste - Plaque, Gingivitis | Phase 3 | Completed | Colgate Palmolive | 95 | 2024-04-22 | 2026-03-19 |
| Clinical Research Study to Assess the Efficacy of Two Brushing Regimens in the Reduction of Established Dental Plaque and Gingivitis. manual Tooth Brush + Colgate Total TP (0.454% SnF, 1100 ppm F), manual toothbrush + Colgate dental cream - Gingivitis, Plaque | Phase 3 | Completed | Colgate Palmolive | 82 | 2024-01-22 | 2026-03-19 |
| A New Mouthwash on Reducing Dental Plaque and Helping Prevent Gum Problems 0.2% zinc lactate, 0.17% amine fluoride and 0.0275% sodium fluoride Mouthwash, 0.057% sodium fluoride Mouthwash - Plaque, Gum Disease | Phase 3 | Completed | Colgate Palmolive | 80 | 2021-03-08 | 2023-04-20 |
| Phase III Trial of Topical Formulation of Sirolimus to Skin Lesions in Patients With Tuberous Sclerosis Complex (TSC) NPC-12G gel, Placebo gel - Tuberous Sclerosis, Angiofibroma | Phase 3 | Completed | Nobelpharma | 62 | 2015-12-01 | 2017-02-02 |
| Long-term Trial of Topical Sirolimus to Angiofibroma in Patient With Tuberous Sclerosis Complex NPC-12G gel - Tuberous Sclerosis, Angiofibroma | Phase 3 | Completed | Nobelpharma | 94 | 2015-12-01 | 2019-02-20 |
| Efficacy of a Mouthwash Containing Propolis Propolis, chlorhexidine - Gingivitis, Periodontitis | Phase 3 | Unknown | Federal University of Minas Gerais | 2 | 2013-02-01 | 2012-12-17 |
Plaque, Amyloid (10) · Gingivitis (7) · Angiofibroma (2) · Tuberous Sclerosis (2) · Dental Plaque (1) · Gingival Diseases (1) · Inflammation (1) · Patient Compliance (1) · Periodontitis (1)
Pathological Conditions, Anatomical (10) · Pathological Conditions, Signs and Symptoms (10) · Mouth Diseases (8) · Periodontal Diseases (8) · Stomatognathic Diseases (8) · Gingival Diseases (7) · Infections (7) · Congenital Abnormalities (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Genetic Diseases, Inborn (2) · Hamartoma (2) · Heredodegenerative Disorders, Nervous System (2) · Malformations of Cortical Development (2) · Malformations of Cortical Development, Group I (2) · Neoplasms (2)
Supersmile (2) · Toothpastes (2) · fluorophosphate (2) · Bicarbonates (1) · Cetylpyridinium (1) · Chlorhexidine (1) · Propolis (1) · cytidylyl-(3'-5')-cytidine (1)
Colgate Palmolive (7) · Nobelpharma (2) · Federal University of Minas Gerais (1)
Italy (2) · Japan (2) · Thailand (2) · United States (2) · Brazil (1) · Puerto Rico (1)
Augusto R. Elias-Boneta, DMD.MSD (1) · Farid Ayad, B.D.S., D.D.S., MSC (1) · Luigi Montensani, DDS (1) · Luigi Montesani, MD, DDS (1) · Mari Wataya-Kaneda, MD, PhD (1) · Mari Wataya-Kaneda,, MD, PhD (1) · Terdphong Triratana (1)