12 completed, 4 unknown, 1 not yet recruiting, 1 withdrawn. 13 Not applicable, 2 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 13 | Completed 10, Not yet recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
Follow Dental Calculus: new trials by email Literature Review of Dental Calculus trials Research Report on Dental Calculus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Bio-Descaling Toothpaste for Dental Calculus Reduction Bio-Descaling Powder (BDP) Toothpaste, Placebo toothpaste - Dental Calculus, Gingivitis and Periodontal Diseases | Not applicable | Not yet recruiting | Universidad Complutense de Madrid | 100 | 2026-07-01 | 2026-07-08 |
| Accuracy of Extra-oral Bite-wing Radiography in Detecting Calculus and Crestal Bone Loss Periodontitis, Calculus, Dental | Unknown | University of Colorado, Denver | 80 | 2023-06-01 | 2023-12-06 | |
| Electric Toothbrush Efficacy in Preventing Dental Plaque Development oscillating toothbrush, standard manual toothbrush - Dental Plaque, Calculus, Dental | Not applicable | Completed | Riccardo Polosa | 100 | 2023-01-30 | 2024-05-17 |
| ONE-1 Oral graNd Est 1 Intra oral cameras - Dental Decay, Periodontal Abscess | Not applicable | Unknown | Central Hospital, Nancy, France | 50 | 2022-06-16 | 2022-07-22 |
| Testing if Tartarase Can Remove Dental Tartar Tartarase - Dental Calculus | Not applicable | Completed | Pontis Biologics, Inc. | 37 | 2022-06-08 | 2023-11-18 |
| Dental Isolation Methods in Pediatric Patients The saliva ejector, The high-volume evacuator, The DryShield - Dental Plaque, Calculus, Dental | Not applicable | Withdrawn | The University of Texas Health Science Center, Houston | 2021-11-01 | 2021-10-29 | |
| The Effect of Virtual Reality Glasses on Dental Anxiety Control Scaling and root planing - Periodontitis, Dental Anxiety | Not applicable | Completed | Kutahya Health Sciences University | 60 | 2021-10-08 | 2023-08-01 |
| ToothWave Calculus Reduction and Accumulation Prevention Study RF-utilizing powered toothbrush, Control placebo with no RF - Gingivitis, Plaque | Not applicable | Completed | Home Skinovations Ltd. | 90 | 2020-07-15 | 2021-04-23 |
| Efficacy of Hyaluronic-acid and Hydrogen-Peroxide Mouthwash in Gingivitis Treatment Filming mouthwash formulation, enriched with Hydrogen Peroxide and Hyaluronic Acid, Chlorhexidine mouthwash, Placebo - Gingivitis, Bleeding Gum | Phase 3 | Unknown | University of Milan | 50 | 2020-06-01 | 2020-06-18 |
| Safety and Efficacy of the ToothWave -12 Weeks Calculus Study RF-utilizing powered toothbrush, Control placebo with no RF - Gingivitis, Plaque | Not applicable | Completed | Home Skinovations Ltd. | 87 | 2019-08-07 | 2020-07-29 |
| Propolis as a Treatment for Cervical Dentin Hypersensitivity desensitizing agents -10% Propolis - Dental Root Sensitivity | Not applicable | Completed | King Khalid University | 75 | 2019-04-01 | 2022-10-20 |
| Infectious Agents Exposure : Archiving in Dental Plaque Infection, Dental Calculus | Unknown | University Hospital, Brest | 15 | 2019-03-04 | 2019-03-06 | |
| ToothWave Plaque and Gingivitis Study RF utilizing powered toothbrush, Control placebo with no RF - Gingivitis, Plaque | Not applicable | Completed | Home Skinovations Ltd. | 86 | 2019-02-28 | 2020-11-25 |
| Evaluation of Root Roughness and Smear Layer Formation Using Conventional and Contemporary Dental Curettes Control group, Gracey Curette, After Five - Dental Calculus | Not applicable | Completed | Dow University of Health Sciences | 120 | 2018-03-07 | 2020-01-07 |
| Efficacy of Toothpaste Containing 0.454% Stannous Fluoride as Compared to a Regular Fluoride Toothpaste Containing 0.76% Sodium Monofluorophosphate in Controlling Supragingival Calculus Formation Over a 12-week Period. 0.454% stannous fluoride, 0.76% sodium monofluorophosphate - Calculus, Dental | Phase 2 / Phase 3 | Completed | Colgate Palmolive | 100 | 2017-05-17 | 2025-12-11 |
| Development of a New Toothpaste for the Removal of Dental Calculus. Bio-descaling D-Tart toothpaste, Crest® toothpaste - Calculus, Dental, Periodontal Diseases | Not applicable | Completed | Faleh Tamimi | 87 | 2017-02-01 | 2020-07-17 |
| Oral Health Literacy Tailored Communication Tailored oral health literacy instruction - Periodontal Diseases, Dental Plaque | Not applicable | Completed | University of Tromso | 179 | 2010-06-01 | 2015-04-16 |
| Staining and Calculus Formation After 0.12% Chlorhexidine Rinses Dental prophylaxis - Dental Calculus, Tooth Discoloration | Phase 2 | Completed | Lutheran University of Brazil | 20 | 2006-06-01 | 2009-01-30 |
Gingivitis (8) · Dental Plaque (6) · Plaque, Amyloid (5) · Periodontal Diseases (3) · Periodontitis (3) · Alveolar Bone Loss (1) · Anodontia (1) · Calculi (1) · Dental Caries (1) · Dentin Sensitivity (1) · Gingival Hemorrhage (1) · Gingival Recession (1) · Hemorrhage (1) · Infections (1)
Dental Deposits (18) · Pathological Conditions, Anatomical (18) · Pathological Conditions, Signs and Symptoms (18) · Stomatognathic Diseases (18) · Tooth Diseases (18) · Calculi (17) · Mouth Diseases (12) · Gingival Diseases (9) · Infections (9) · Periodontal Diseases (9) · Periodontal Atrophy (2) · Abscess (1) · Bacterial Infections (1) · Bacterial Infections and Mycoses (1) · Bone Diseases (1)
Control Groups (1) · Dental Prophylaxis (1) · Hyaluronic Acid (1) · Hydrogen Peroxide (1) · Root Planing (1) · Tin Fluorides (1) · Tooth Exfoliation (1) · Toothpastes (1) · alpha-ketoisovalerate dehydrogenase phosphatase (1) · fluorophosphate (1)
Home Skinovations Ltd. (3) · Central Hospital, Nancy, France (1) · Colgate Palmolive (1) · Dow University of Health Sciences (1) · Faleh Tamimi (1) · King Khalid University (1) · Kutahya Health Sciences University (1) · Lutheran University of Brazil (1) · Pontis Biologics, Inc. (1) · Riccardo Polosa (1) · The University of Texas Health Science Center, Houston (1) · Universidad Complutense de Madrid (1) · University Hospital, Brest (1) · University of Colorado, Denver (1) · University of Milan (1)
United States (5) · France (2) · Italy (2) · Canada (1) · Norway (1) · Pakistan (1) · Saudi Arabia (1) · Thailand (1) · Turkey (Türkiye) (1)
Bennett T Amaechi, BDS, MS, PhD (1) · Dennis C. Mynarcik, PhD (1) · Di I Wu, DDS,MS,PhD (1) · Dutmanee Seriwatanachai (1) · Giampietro Farronato, Professor (1) · Gianguido Cossellu, Fellow (1) · Jan O Bergdahl, Professor (1) · Jeffery L Milleman, DDS, MPA (1) · Jeffry L. Milleman, DDS, MPA (1) · Luc de Saint-Martin, MD, Ph (1) · Raghavendra R Nagate, MDS (1) · Sania Riaz (1) · William Carter, DDS (1)
PMID 14326695, PMID 21085810, PMID 33047816, PMID 35715802, PMID 37012012, PMID 38909189, PMID 42391887