4 completed, 1 recruiting, 1 withdrawn. 6 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 4, Recruiting 1, Withdrawn 1 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
Follow Phantom Limb: new trials by email Literature Review of Phantom Limb trials Research Report on Phantom Limb
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Trial Exploring the Outpatient Treatment of Phantom Limb Pain With Ketamine Administration in a Six Month Study With a Minimum Remission Period of 7 Days Between Treatment Session. 25-30 Subjects With an Ongoing History of Significant PLP.--FDA and IRB Approved. IM ketamine in dose finding and then continuation - Phantom Limb Syndrome With Pain | Phase 2 / Phase 3 | Recruiting | The Ketamine Research Foundation | 30 | 2026-01-15 | 2026-03-18 |
| A Trial of Lidocaine Patch for Lower Limb Amputation Pain Lidocaine, Sham - Phantom Limb Pain (PLP), Primary/Secondary Scar Hyperalgesia | Phase 2 | Withdrawn | Brugmann University Hospital | 2016-05-13 | 2018-01-23 | |
| Valproic Acid for the Prevention of Post-Amputation Pain Valproic Acid, Cherry Syrup - Pain, Phantom, Pain, Neuropathic | Phase 2 | Completed | Duke University | 128 | 2013-12-01 | 2018-12-19 |
| Nabilone for the Treatment of Phantom Limb Pain Nabilone - Phantom Limb Pain, Neuropathic Pain | Phase 2 | Completed | University of Manitoba | 50 | 2009-01-01 | 2011-04-29 |
| Optimized Perioperative Analgesia Reduces the Prevalence and the Intensity of Phantom Pain in Lower Limb Amputation perioperative epidural catheter - Phantom Limb Pain | Phase 2 / Phase 3 | Completed | University of Patras | 60 | 2003-12-01 | 2011-11-07 |
| Efficacy of Opioids and Mexiletine for the Treatment of Postamputation Pain morphine and mexiletine - Amputation, Chronic Pain | Phase 2 | Completed | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 60 | 1997-07-01 | 2006-10-03 |
Pain (3) · Neuralgia (2) · Agnosia (1) · Chronic Pain (1)
Nervous System Diseases (6) · Neurobehavioral Manifestations (6) · Neurologic Manifestations (6) · Pain, Postoperative (6) · Pathologic Processes (6) · Pathological Conditions, Signs and Symptoms (6) · Perceptual Disorders (6) · Postoperative Complications (6) · Signs and Symptoms (6) · Pain (3) · Neuromuscular Diseases (2) · Peripheral Nervous System Diseases (2)
Lidocaine (1) · Mexiletine (1) · Morphine (1) · Valproic Acid (1) · nabilone (1) · salicylhydroxamic acid (1)
Brugmann University Hospital (1) · Duke University (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · The Ketamine Research Foundation (1) · University of Manitoba (1) · University of Patras (1)
United States (3) · Belgium (1) · Canada (1) · Greece (1)
Diamanto N. Aretha, MD (1) · Georgia Monantera, MD (1) · Ioannis Tsolakis, MD Professor (1) · Kriton S Filos, MD Professor (1) · Menelaos Karanikolas, MD, MPH (1) · Ryan Q Skrabek, MD, FRCPC (1) · Samar Hatem, MD (1) · Simone Brienza, MD (1) · Srinivasa N Raja, M.D. (1) · Thomas E Buchheit, MD (1)