17 completed, 6 unknown, 3 recruiting, 2 terminated. 19 Not applicable, 4 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 19 | Completed 9, Recruiting 3, Unknown 3, Terminated 2, Active not recruiting 1, Not yet recruiting 1 |
| Phase 4 | 4 | Completed 3, Unknown 1 |
Follow Oxygen Toxicity: new trials by email Literature Review of Oxygen Toxicity trials Research Report on Oxygen Toxicity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Hydrogen Gas on Hyperbaric Oxygen Toxicity Inhaled Hydrogen-Enriched Oxygen Gas, Inhaled Nitrogen-Enriched Oxygen Gas - Oxygen Toxicity, Oxidative Stress | Not applicable | Not yet recruiting | Blekinge Institute of Technology | 32 | 2026-01-01 | 2025-12-04 |
| Epidemiological Assessment of Technical Diving Accidents in Mainland France and Factors Predictive of Severity (TEKCare) Decompression Sickness, Pulmonary Edema - Acute | Unknown | University Hospital, Brest | 100 | 2025-01-01 | 2024-10-04 | |
| Comparison of Several Oxygenation Targets With Different Oxygen Interfaces - Impact on Oxygen Flow Rates Nasal canula - up to 6 liters per minute, Nasal canula - up to 15 liters per minute, Open oxygen mask - Oxygen Toxicity, COPD Bronchitis | Not applicable | Recruiting | Laval University | 20 | 2024-11-27 | 2026-11-05 |
| Oxygen Toxicity: Mechanisms in Humans Sleep Deprivation, Caffeine, Methylphenidate - Oxygen Toxicity, Hypercapnia | Not applicable | Recruiting | Duke University | 62 | 2023-11-28 | 2026-10-21 |
| Effects of Pre-dive Ketone Food Products on Latency to CNS Oxygen Toxicity (Aim 2) Ketogenic food products, Control: Placebo - Oxygen Toxicity | Not applicable | Completed | Duke University | 20 | 2023-09-01 | 2026-04-03 |
| Effects of Pre-dive Ketone Food Products on Latency to CNS Oxygen Toxicity (Aim 1) Ketogenic food products - Oxygen Toxicity | Not applicable | Completed | Duke University | 15 | 2023-05-01 | 2025-05-31 |
| Lung Ultrasound Guided Choice of Best Positive End-Expiratory Pressure in Neonatal Anesthesia LUS-guided choice of Peep, Standard choice of Peep - Oxygen Toxicity, Anesthesia; Adverse Effect | Not applicable | Unknown | Vittore Buzzi Children's Hospital | 280 | 2023-03-01 | 2024-05-10 |
| Hyperoxia Induced Pulmonary Inflammation and Organ Injury: a Human in Vivo Model Liquid oxygen, medical air - Oxygen Toxicity, Pulmonary Injury | Not applicable | Unknown | Belfast Health and Social Care Trust | 53 | 2022-12-02 | 2024-01-29 |
| Comparison of Two Oxygenation Targets With Two Different Oximeters - Impact on Oxygen Flow Rates and Oxygenation Manual Oxygen titration with Philips oximeter (SpO2 target 90%), Manual oxygen titration with Nonin oximeter (SpO2 target 90%), Manual Oxygen titration with Philips oximeter (SpO2 target 94%) - Oxygen Toxicity, Respiratory Failure | Not applicable | Recruiting | Laval University | 40 | 2022-11-16 | 2026-11-05 |
| Automated Versus Manual Control Of Oxygen For Preterm Infants On Continuous Positive Airway Pressure In Nigeria OxyMate, Manual oxygen control - Neonatal Respiratory Distress Related Conditions, Neonatal Respiratory Failure | Not applicable | Completed | Murdoch Childrens Research Institute | 49 | 2022-09-13 | 2023-11-13 |
| Comparison of the Acute Effects of Chest Physiotherapy Methods Applied in Different Positions in Preterm Newborns chest physiotherapy - Preterm Birth, Premature | Not applicable | Completed | Sanko University | 60 | 2022-04-01 | 2025-09-12 |
| Restrictive Vs. Liberal Oxygen in Trauma Restrictive oxygen, Liberal oxygen - Trauma, Oxygen Toxicity | Phase 4 | Completed | Copenhagen University Hospital, Rigshospitalet | 1508 | 2021-12-10 | 2024-10-22 |
| Handling Oxygenation Targets in COVID-19 Low oxygenation target, High oxygenation target - Hypoxemic Respiratory Failure, Oxygen Toxicity | Phase 4 | Completed | Aalborg University Hospital | 726 | 2020-08-25 | 2024-07-15 |
| Fetal Haemoglobin and Cerebral and Peripheral Oxygenation. Near-infrared spectroscopy - Preterm Birth, Oxygen Toxicity | Completed | Medical University of Graz | 50 | 2020-06-08 | 2024-07-03 | |
| Closed-Loop Oxygen to Verify That Healthcare Workers Interventions Decrease During SARS-CoV-2 Pneumonia (COVID-19) Standard administration of oxygen flow, Automated oxygen administration - FreeO2 - Coronavirus, Pneumonia | Not applicable | Unknown | Laval University | 216 | 2020-04-20 | 2020-04-21 |
| Influence of FreeO2 on Percentage of Time Within Oxygen Saturation Target Using Noninvasive Ventilation (NIV) and Continuous Positive Airway Pressure (CPAP) for Patients Admitted for AECOPD or Bariatric Surgery Washout period, NIV - FreeO2, Nasal High flow Oxygen therapy - FreeO2 - COPD Exacerbation, Oxygen Toxicity | Not applicable | Active not recruiting | François Lellouche | 10 | 2019-10-28 | 2026-11-05 |
| Northern Survey on Therapeutic Oxygen Prescription 17 items questionaire - Oxygen Toxicity | Unknown | Hannover Medical School | 500 | 2019-07-02 | 2019-08-07 | |
| Automated Adjustment of Oxygen on Patient With Acute COPD Exacerbation - FreeO2 HypHop FreeO2, manual titration - Oxygen Toxicity, COPD Exacerbation | Not applicable | Terminated | Laval University | 17 | 2018-12-17 | 2025-09-04 |
| ORI to Reduce Hyperoxia After Out Hospital Cardiac Arrest ORI measurement, oxygen saturation measurement - Out-Of-Hospital Cardiac Arrest, Oxygen Toxicity | Not applicable | Completed | Centre Hospitalier Universitaire Saint Pierre | 100 | 2018-11-08 | 2022-05-19 |
| Lower Inspiratory Oxygen Fraction for Preoxygenation Pure oxygen group, Lower oxygen group - Intraoperative Complications, Respiratory Complication | Not applicable | Terminated | E-DA Hospital | 304 | 2018-11-01 | 2019-02-27 |
Showing 20 of 30. Sign in to see all of them.
Hyperoxia (8) · Hypoxia (4) · Respiratory Insufficiency (4) · Critical Illness (3) · Premature Birth (3) · Respiratory Distress Syndrome (3) · Acute Lung Injury (2) · Pulmonary Atelectasis (2) · Wounds and Injuries (2) · Bronchopulmonary Dysplasia (1) · Coronavirus Infections (1) · Decompression Sickness (1) · Hyaline Membrane Disease (1) · Hypercapnia (1) · Inert Gas Narcosis (1)
Pathological Conditions, Signs and Symptoms (15) · Signs and Symptoms (13) · Signs and Symptoms, Respiratory (11) · Respiratory Tract Diseases (9) · Lung Diseases (7) · Respiration Disorders (5) · Pathologic Processes (4) · Disease Attributes (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Obstetric Labor Complications (3) · Obstetric Labor, Premature (3) · Pregnancy Complications (3) · Urogenital Diseases (3) · Body Weight (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2)
Hyperbaric Oxygenation (3) · Oxygen (2) · Air (1) · Caffeine (1) · Diet, Ketogenic (1) · Intubation, Intratracheal (1) · Methylphenidate (1) · Oximetry (1) · Respiration, Artificial (1) · Sodium Bicarbonate (1) · Spectroscopy, Near-Infrared (1) · nitrox (1)
Laval University (4) · Aalborg University Hospital (3) · Duke University (3) · Assaf-Harofeh Medical Center (1) · Belfast Health and Social Care Trust (1) · Blekinge Institute of Technology (1) · Centre Hospitalier Universitaire Saint Pierre (1) · Copenhagen University Hospital, Rigshospitalet (1) · E-DA Hospital (1) · François Lellouche (1) · Hannibal Troensegaard (1) · Hannover Medical School (1) · Karolinska University Hospital (1) · Medical University of Graz (1) · Murdoch Childrens Research Institute (1)
Canada (6) · Denmark (5) · United States (4) · Sweden (3) · Switzerland (3) · Netherlands (2) · Norway (2) · United Kingdom (2) · Austria (1) · Belgium (1) · Finland (1) · France (1) · Germany (1) · Iceland (1) · Israel (1)
Bodil Steen Rasmussen, MD, PhD (2) · Bruce Derrick, MD (2) · Adit Ginde, MD, MPH (1) · Amir Hadanny, MD (1) · Anders Perner, MD, PhD (1) · Bodil S Rasmussen, MD (1) · Bosco Gerardo, MD, PhD (1) · Chen-Fuh Lam, MD, PhD (1) · Danny McAuley, MD (1) · Francois Lellouche (1) · Gerhard Pichler, Prof (1) · Hamish R Graham, PhD (1) · Jacob Steinmetz, MD, PhD (1) · Jens Gottlieb, Prof. Dr. med. (1) · Johan Agren, MD, PhD (1)
PMID 38990335, PMID 40920961, PMID 17015549, PMID 17486089, PMID 18234457, PMID 21037284, PMID 23475767, PMID 26447264, PMID 26863265, PMID 27573518, PMID 27634820, PMID 29296004, PMID 29872859, PMID 30389451, PMID 31229956, PMID 31409407, PMID 31462405, PMID 31715041, PMID 32659856, PMID 33471452, PMID 33963005, PMID 34039929, PMID 34112721, PMID 34425016, PMID 34511288, PMID 34674834, PMID 35441849, PMID 36344005, PMID 36906804, PMID 37196799, PMID 37256885, PMID 37364027, PMID 37588787, PMID 37863418, PMID 38501214, PMID 38711834, PMID 39303806, PMID 39425927, PMID 39657224, PMID 39890225, PMID 39911528, PMID 39939102, PMID 42722424
2017 (2)