13 completed, 3 unknown, 2 not yet recruiting, 2 recruiting. 6 Not applicable, 2 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 4, Recruiting 2 |
| Phase 2 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Decompression Sickness: new trials by email Literature Review of Decompression Sickness trials Research Report on Decompression Sickness
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Health, Fitness, and Safety Knowledge as Determinants of Adverse Events in Recreational Divers in Poland Anonymous online questionnaire - Decompression Sickness, Barotrauma | Not yet recruiting | Medical University of Bialystok | 384 | 2026-10-01 | 2026-10-02 | |
| NASA Exercise Prebreathe Study Oxygen Prebreathe and Hypobaric Exposure - Decompression Sickness | Not applicable | Recruiting | Duke University | 30 | 2026-08-13 | 2026-10-05 |
| Rhu-pGSN to Mitigate Proinflammatory Responses to Decompression in Healthy SCUBA Divers Sodium Chloride 0.9% Inj pre-exposure, Sodium Chloride 0.9% Inj post-exposure, Recombinant human plasma gelsolin pre-exposure - Decompression Sickness | Phase 2 | Completed | BioAegis Therapeutics Inc. | 36 | 2025-08-15 | 2026-10-02 |
| NASA Prebreathe Study Altitude, 100% Oxygen - Decompression Sickness | Phase 1 | Completed | Duke University | 19 | 2025-05-05 | 2026-06-01 |
| Epidemiological Assessment of Technical Diving Accidents in Mainland France and Factors Predictive of Severity (TEKCare) Decompression Sickness, Pulmonary Edema - Acute | Unknown | University Hospital, Brest | 100 | 2025-01-01 | 2024-10-04 | |
| Prediction & Mechanisms of Recovery Following IEDS Decompression Sickness | Not yet recruiting | University of Plymouth | 41 | 2024-06-01 | 2024-05-13 | |
| Impact of Hyperoxia and Involvement of the Immune System in Diving Accident Hyperbaric oxygen therapy, Diving simulation - Decompression Sickness | Not applicable | Recruiting | Direction Centrale du Service de Santé des Armées | 265 | 2022-03-30 | 2023-04-28 |
| Decompression Tables for Diving at Altitude Pressure, Breathing Gas - Decompression Sickness, Acute Mountain Sickness | Not applicable | Completed | Duke University | 103 | 2018-02-13 | 2021-12-14 |
| Inflammatory and Cerebrospinal Biochemical Markers in Blood After Trimix Diving Exposure to oxygen partial pressure of 130 kPa, Exposure to ambient pressure of maximum 11 ATA - Diving Medicine, Inflammation | Completed | Sahlgrenska University Hospital | 10 | 2017-06-12 | 2019-03-12 | |
| Markers of Central Nervous System Injury in Decompression Sickness No active intervention - Decompression Sickness | Unknown | Sahlgrenska University Hospital | 40 | 2017-05-01 | 2023-12-14 | |
| Inflammatory and Cerebrospinal Biochemical Markers in Blood During Prolonged Hyperbaric Exposure Hyperbaric exposure - Saturation Exposure, Decompression Injury | Completed | Sahlgrenska University Hospital | 26 | 2017-03-17 | 2019-04-09 | |
| Decreases in Diffusing Lung Capacity for Carbon Monoxide (DLCO) in Occupational Divers and Their Impact on Decompression Sickness Risks 20 meters air dive - Decompression Sickness | Not applicable | Completed | University Hospital, Brest | 16 | 2016-03-22 | 2017-06-14 |
| Decompression Sickness in Divers With or Without Patent Foramen Ovale Foramen Ovale, Patent, Decompression Sickness | Completed | Sejong General Hospital | 100 | 2015-05-01 | 2021-08-24 | |
| Reduction of Venous Emboli Load After Breathing Normobaric Oxygen Compared to Air Oxygen, Air - Hyperbaric, Diving Medicine | Phase 2 / Phase 3 | Completed | Göteborg University | 48 | 2015-05-01 | 2022-05-27 |
| A Descriptive Analysis of Diving Accidents Treated at the Hyperbaric Chamber of Nice Hospital Between 2014 and 2025 medical care in a hyperbaric unit - Decompression Sickness, Diving | Completed | Centre Hospitalier Universitaire de Nice | 468 | 2014-04-27 | 2026-06-02 | |
| Exercise and Repetitive Diving Aerobic running exercise - Decompression Sickness, Endothelial Dysfunction | Not applicable | Completed | University of Split | 16 | 2013-10-01 | 2014-04-21 |
| Nitrogen Bubble Detection After Simulated Dives in Divers With PFO and After PFO Closure Patent Foramen Ovale | Completed | University Hospital, Motol | 47 | 2013-05-01 | 2013-12-18 | |
| High Intensity Cycling Before SCUBA Diving Reduces Post-decompression Microparticle Production and Neutrophil Activation High intensity exercise - Decompression Sickness, SCUBA Diving | Not applicable | Completed | University of Split | 10 | 2013-02-01 | 2014-02-17 |
| Microparticles in Scuba Divers With Decompression Sickness Decompression Sickness, Dysbarism | Completed | University of Pennsylvania | 1 | 2011-08-01 | 2016-08-22 | |
| Hyperbaric Oxygen Therapy Registry Air or Gas Embolism, Carbon Monoxide Poisoning | Unknown | U.S. Wound Registry | 5000 | 2005-01-01 | 2018-05-01 |
Inflammation (4) · Barotrauma (2) · Foramen Ovale, Patent (2) · Motor Activity (2) · Altitude Sickness (1) · Anemia (1) · Anthrax (1) · Carbon Monoxide Poisoning (1) · Compartment Syndromes (1) · Crush Injuries (1) · Embolism, Air (1) · Gas Gangrene (1) · Inert Gas Narcosis (1) · Osteomyelitis (1)
Wounds and Injuries (20) · Barotrauma (18) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Cardiovascular Diseases (3) · Behavior (2) · Cardiovascular Abnormalities (2) · Chemically-Induced Disorders (2) · Congenital Abnormalities (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Gas Poisoning (2) · Heart Defects, Congenital (2) · Heart Diseases (2) · Heart Septal Defects (2) · Heart Septal Defects, Atrial (2)
Oxygen (2) · Air (1) · Altitude (1) · High-Intensity Interval Training (1) · Hyperbaric Oxygenation (1) · Pressure (1) · Saline Solution (1) · Sodium Chloride (1)
Duke University (3) · Sahlgrenska University Hospital (3) · University Hospital, Brest (2) · University of Split (2) · BioAegis Therapeutics Inc. (1) · Centre Hospitalier Universitaire de Nice (1) · Direction Centrale du Service de Santé des Armées (1) · Göteborg University (1) · Medical University of Bialystok (1) · Sejong General Hospital (1) · U.S. Wound Registry (1) · University Hospital, Motol (1) · University of Pennsylvania (1) · University of Plymouth (1)
United States (7) · Sweden (4) · France (3) · Croatia (2) · Czechia (1) · Poland (1) · South Korea (1)
Henrik Zetterberg, PhD (3) · Jakub Honek, MD (1) · Josef Veselka, MD, PhD (1) · Mikael Gennser, PhD (1) · Richard E Moon, MD (1) · Richard Moon (1) · Richard Moon, MD (1) · Stephen R Thom, MD,PhD (1) · Zeljko Dujic, MD, PhD (1) · Zeljko Dujic, MD. PhD (1)