19 completed, 3 withdrawn, 2 not yet recruiting, 1 recruiting. 27 Phase 1, 8 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 27 | Completed 19, Withdrawn 3, Not yet recruiting 2, Recruiting 1, Terminated 1, Unknown 1 |
| Phase 2 | 8 | Completed 4, Not yet recruiting 2, Recruiting 1, Terminated 1 |
Follow Oxidative Stress: new trials by email Literature Review of Oxidative Stress trials Research Report on Oxidative Stress
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Relaxin Therapy for Atrial Fibrillation Relaxin, Placebo - Atrial Fibrillation (AF), Arrhythmia | Phase 1 / Phase 2 | Not yet recruiting | Deeptankar DeMazumder | 208 | 2027-01-01 | 2026-01-22 |
| Impact of Chromium Supplementation on Glucido-lipidic Metabolism, Oxidative Stress and Inflammatory State in Patients with Gestational Diabetes Oral chromium supplementation during gestational diabetes mellitus through the administration of chromium picolinate tablets (200 µg/d), Dietary Supplement: Oral chromium supplementation during gestational diabetes mellitus through the administration of chromium picolinate tablets (400 µg/d) - Gestational Diabetes Mellitus (GDM), Oxidative Stress | Phase 1 / Phase 2 | Not yet recruiting | University of Kasdi Merbah | 200 | 2025-05-01 | 2025-03-05 |
| Effect of Supplementation With Anthocyanins on Iron Metabolism in Female Swimmers Black chokeberry extract in capsules with 18% standardization of the anthocyanins content, Chokeberry fiber in capsules - Iron Deficiencies, Inflammation | Phase 1 / Phase 2 | Completed | Poznan University of Physical Education | 22 | 2023-03-01 | 2024-07-03 |
| Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia Drug Lowering Cerebral Blood Flow (CBF) and Normoxia Sleep, Drug Lowering CBF and Intermittent Hypoxia Sleep, Placebo and Normoxia Sleep - Obstructive Sleep Apnea of Adult, Hypoxia, Brain | Phase 1 / Phase 2 | Recruiting | University of Calgary | 12 | 2023-01-01 | 2026-05-01 |
| NAC Treatment and Outcomes in Patients With Advanced Atherosclerosis and DM N-acetylcysteine, Placebo - Atherosclerosis of Artery, Peripheral Artery Disease | Phase 1 | Withdrawn | University of Missouri-Columbia | 2021-10-15 | 2023-06-18 | |
| O2 Transport and Utilization in Health and Lung Disease Tetrahydrobiopterin, Placebo oral tablet - COPD, Tetrahydrobiopterin Deficiency | Phase 1 | Withdrawn | University of Massachusetts, Amherst | 2021-04-01 | 2023-12-19 | |
| Effects of Olive Oil and Bran Oil on Antioxidant Levels, Glycemic Control, and Lipid Profile in Patient Type 2 DM olive oil, bran oil - Diabetes Mellitus, Type 2, Oxidative Stress | Phase 1 | Completed | Universitas Indonesia | 10 | 2018-07-02 | 2018-10-16 |
| Bioavailability and Impact of Coenzyme Q10 in Stressing Exercise in Senescence Athletes Administration of a product with Fitosomed Ubiquinone, Coenzyme Q10 level in muscle biopsies, Coenzyme Q10 level in plasma, blood cells, urine cells - Coenzyme Q10, Oxidative Stress | Phase 1 | Completed | Centre d'Alt Rendiment | 22 | 2018-03-01 | 2019-03-28 |
| Racial Differences in Vagal Control of Glucose Homeostasis, Chronic Study Galantamine, Placebo - Insulin Sensitivity, Oxidative Stress | Phase 1 | Withdrawn | Vanderbilt University Medical Center | 2017-01-01 | 2018-08-13 | |
| Xanthohumol and Prevention of DNA Damage 6 mg xanthohumol per day, 12 mg xanthohumol per day, 24 mg xanthohumol per day - Oxidative Stress | Phase 1 | Completed | Oregon State University | 64 | 2015-03-01 | 2018-11-06 |
| N-acetylcysteine to Reduce Oxidative Stress and Improve Endothelial Function in HIV-infected Older Adults PharmaNAC (N-acetylcysteine), Matching placebo - HIV, Endothelial Dysfunction | Phase 1 / Phase 2 | Completed | Indiana University | 24 | 2013-10-01 | 2016-02-08 |
| Once-Daily Oral Dose of BeneFlax to Healthy Older Adults secoisolariciresinol diglucoside, vitamin D - Oxidative Stress, Inflammation | Phase 1 / Phase 2 | Completed | University of Saskatchewan | 32 | 2013-04-01 | 2018-06-14 |
| Flaxseed Modulates Inflammation and Oxidative Stress in CF finely ground flaxseed powder - Cystic Fibrosis, Oxidative Stress | Phase 1 | Completed | University of Pennsylvania | 10 | 2012-07-01 | 2014-01-07 |
| Effect of an Iridoid Enriched Beverage on Skin Autofluorescence iridoid enriched mixed fruit beverage - Oxidative Stress, Quality of Life | Phase 1 | Completed | Tahitian Noni International, Inc. | 34 | 2012-05-01 | 2014-12-04 |
| Safety and Tolerability of Antioxidant (AT-001)for Reducing Brain Oxidative Stress AT-001, Placebo - Oxidative Stress | Phase 1 | Completed | Alltech Life Sciences Inc. | 24 | 2012-03-01 | 2014-01-23 |
| Investigations of Botanicals on Food Intake, Satiety, Weight Loss, and Oxidative Stress Microcrystalline Cellulose placebo pill, Garcinia cambogia-derived hydroxycitric acid (2800 mg/day), Garcinia Cambogia derived Hydroxycitric Acid - Obesity, Oxidative Stress | Phase 1 / Phase 2 | Terminated | University of Florida | 17 | 2011-07-01 | 2014-03-31 |
| Lime Powder Regimen in Healthy Volunteers Lime powder regime - Kidney Stone, Oxidative Stress | Phase 1 | Unknown | Chulalongkorn University | 15 | 2010-12-01 | 2011-01-10 |
| The Effects of a Glutathione Precursor (FT061452),on Serum and Intracellular Glutathione Levels Placebo low dose, N Acetyl cysteine, 600mg (low dose), Proimmune 200 (FT061452) 3000mg low dose - Oxidative Stress | Phase 1 | Completed | Charles Drew University of Medicine and Science | 24 | 2010-12-01 | 2014-04-14 |
| Pentriox - Induction of Oxidative Stress Penicillin V, Trimethoprim, Placebo - Oxidative Stress | Phase 1 | Completed | Henrik Enghusen Poulsen | 90 | 2010-11-01 | 2014-07-11 |
| Physiological Effects of Grape Seed Extract in Diastolic Heart Failure grape seed extract (MegaNatural BP, Polyphenolics, Inc.) - Diastolic Heart Failure, Hypertensive Heart Disease | Phase 1 | Completed | University of Michigan | 15 | 2010-10-01 | 2017-06-06 |
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Inflammation (6) · Insulin Resistance (3) · Stroke (3) · Heart Failure (2) · Hyperlipidemias (2) · Lipid Metabolism Disorders (2) · Motor Activity (2) · Obesity (2) · Alzheimer Disease (1) · Arrhythmias, Cardiac (1) · Atherosclerosis (1) · Atrial Fibrillation (1) · Body Weight (1) · Cardiovascular Diseases (1) · Cystic Fibrosis (1)
Pathological Conditions, Signs and Symptoms (13) · Nutritional and Metabolic Diseases (11) · Metabolic Diseases (10) · Pathologic Processes (9) · Nervous System Diseases (6) · Brain Diseases (5) · Cardiovascular Diseases (5) · Central Nervous System Diseases (5) · Glucose Metabolism Disorders (5) · Signs and Symptoms (5) · Vascular Diseases (5) · Endocrine System Diseases (4) · Hyperinsulinism (4) · Cerebrovascular Disorders (3) · Female Urogenital Diseases and Pregnancy Complications (3)
Acetylcysteine (3) · Thioctic Acid (2) · Anthocyanins (1) · Antioxidants (1) · CD2 Antigens (1) · Capsules (1) · Cellulose (1) · Cerebrovascular Circulation (1) · Clarithromycin (1) · Core Binding Factors (1) · Fatty Acids, Omega-3 (1) · Fish Oils (1) · Flavonoids (1) · Flavonols (1) · Galantamine (1)
Universitas Indonesia (2) · Alltech Life Sciences Inc. (1) · Centre d'Alt Rendiment (1) · Charles Drew University of Medicine and Science (1) · Chulalongkorn University (1) · Copenhagen University Hospital, Rigshospitalet (1) · Deeptankar DeMazumder (1) · Henrik Enghusen Poulsen (1) · Indiana University (1) · Oregon Health and Science University (1) · Oregon State University (1) · Poznan University of Physical Education (1) · Tahitian Noni International, Inc. (1) · University of Calgary (1) · University of California, San Francisco (1)
United States (12) · Canada (3) · Indonesia (3) · Denmark (2) · Algeria (1) · China (1) · Poland (1) · Spain (1) · Thailand (1)
A V Rao, PhD (1) · Claude J Jensen, MS (1) · Cyndya A Shibao, MD (1) · Deeptankar DeMazumder, MD, PhD (1) · Denis Hadjiliadis, MD (1) · Dwirini R Gunarti, DR (1) · Gregory A Jicha, MD, PhD (1) · Henrik E Poulsen, MD (1) · Henrik E Poulsen, dr. med. (1) · Ira Goldfine, MD (1) · Jan Frederik Stevens, PhD (1) · Jane Alcorn, DVD, PhD (1) · Jason B Turowski, MD (1) · Jennifer Jones, MD, FRCPC (1) · Kerry Mansell, BSP, PharmD (1)
PMID 20307398, PMID 21593349, PMID 22088584, PMID 24077434, PMID 25963404, PMID 28159728
K23AT004251 (1), M01RR000334 (1), R21AG023805 (1), R21AT003892 (1)